I was diagnosized with type 2 diabetic in 2004 with a1c 6.5 and my a1c
for 2005(one year later) is about the same level. In order to reduce
a1c, I went on dieting. As result of dieting
1. I lost 30lbs (normal BMI after weight loss),
2. my lipid profile is normal(used to have triglyceride 355 and it is
108).
3. my a1c is within normal range during past 10 months.
4. my 2hr glucose tolerance test is normal (108 before glucose in the
morning and
97 two
hours later).
I developed symmetric polyneuropathy symptom nov. 2005 with following
symptoms
1. pins/needle and numbness all over my body legs,feet, arms, hands,
faces, body.
2. burning sensations on my feet and buttock(especially after sitting).
3. weakness in my hands and foot.
4. weakness in my waist area and I have problem sitting for long with
lean against
back of the chair and standing for long.
5. dizziness(not because of abnormal blood pressure).
Here are my questions,
1. why my neuropathic symptoms are getting worse, while glycemic
control is getting better,
if neuropathy is caused by diabetic conditions.
2. Have any one experience weakness in waist area due to diabetic
peripheral neuropathy ?
3. All neuro tests/mri/ct turned out to be negative. My neurologist
tells me it is probably
caused by prior diabetic condition and endocriologist think there is
something else
is going on and I am at lost.
thanks a lot lee
Susan - 11 Aug 2006 17:38 GMT
> Here are my questions,
>
[quoted text clipped - 10 lines]
> something else
> is going on and I am at lost.
Lee, it's entirely possible to be diabetic and to have another condition
that causes problems, as your endocrinologist suggests.
There are infectious diseases that can cause symptoms like yours, among
them tick borne diseases, which are treatable with antibiotics, or viral
diseases which may have other treatments.
Perhaps a broad medical evaluation along with a thorough infectious
disease screening might be wise? Maybe ask your endo what he/she thinks
about this course of action?
Sorry you're having such problems.
Susan
lee - 11 Aug 2006 18:21 GMT
susan,
thanks for the inputs.
all infectious disease(lyme, hepatitis etc) and nutritional(b12 etc)
and emg are negative.
I have small fiber peripheral neuropathy(not detected by emg).
> x-no-archive: yes
>
[quoted text clipped - 27 lines]
>
> Susan
Susan - 11 Aug 2006 19:13 GMT
> susan,
> thanks for the inputs.
>
> all infectious disease(lyme, hepatitis etc) and nutritional(b12 etc)
> and emg are negative.
> I have small fiber peripheral neuropathy(not detected by emg).
It's possible to have certain infectious diseases undetected by serology.
I'm not saying that's what you have, just saying that it's possible to
have it and to come out negative on all diagnostic serology. :-/
Whatever it is, I hope you find out the cause and feel better soon.
Susan
lee - 11 Aug 2006 21:53 GMT
susan,
can you tell me more about diagnostic serology ?
> x-no-archive: yes
>
[quoted text clipped - 13 lines]
>
> Susan
Susan - 11 Aug 2006 22:03 GMT
> susan,
> can you tell me more about diagnostic serology ?
That's just a term for blood tests. They aren't 100% accurate, and in
the case of tick borne diseases, particularly Lyme, they are notoriously
inaccurate for a whole host of reasons. The western blot, for example,
is based upon a protein expressed by only 80 of about 300 genetic
strains of the bacterium, and if you get bit by the wrong tick it misses
the antibodies. There's a lot of peer reviewed literature demonstrating
cases of seronegative Lyme disease, for example.
I know most about tick borne infections, which cause huge neurological
problems, often indistinguishable from ALS and MS, for example. I'm
sure there are other infections that can do similar things, though I
can't name them.
Susan
Emmett Galsworthy - 12 Aug 2006 00:16 GMT
Hi, I'm a lurker, but I remember just this syndrome described in a medscape
article about a year and a half to two years ago. It was identified as
neuropathy in the "girdle" area, with an unusually early onset in Type II
diabetics.
I'm not sure if Medscape articles are archived.
HTH
Em
>I was diagnosized with type 2 diabetic in 2004 with a1c 6.5 and my a1c
> for 2005(one year later) is about the same level. In order to reduce
[quoted text clipped - 37 lines]
>
> thanks a lot lee
Susan - 12 Aug 2006 01:05 GMT
> Hi, I'm a lurker, but I remember just this syndrome described in a medscape
> article about a year and a half to two years ago. It was identified as
> neuropathy in the "girdle" area, with an unusually early onset in Type II
> diabetics.
> I'm not sure if Medscape articles are archived.
I just read that case study, today! It's archived on medrant.com, I
can't find it now, but it was written in a rant under the "clinical"
link on the right side in a rant about clinical judgment.
Susan