Medical Forum / Diseases and Disorders / Diabetes / April 2006
Inhalable insulin -- Exubera
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Noguru - 06 Apr 2006 07:07 GMT I'm a T2, and as something of a control fanatic I've used Starlix (nateglenide) to boost insulin production after meals. My diabetologist suggests that I'd make a good First Patient for Exubera.
Has anyone else heard that from his/her physician? The idea is that this would reduce postprandial peaks - which, of course, is what do the damage.
Control freak
ted rosenberg - 06 Apr 2006 16:06 GMT > I'm a T2, and as something of a control fanatic I've used Starlix > (nateglenide) to boost insulin production after meals. My diabetologist [quoted text clipped - 4 lines] > > Control freak Like most meds, you have to try it to see how (and if) it will jelp you.
Beware of lung problems, a real risk - I have also heard that it isn't as accurate, but cant confirm that.
Flying Rat - 06 Apr 2006 19:12 GMT > > I'm a T2, and as something of a control fanatic I've used Starlix > > (nateglenide) to boost insulin production after meals. My diabetologist [quoted text clipped - 8 lines] > Beware of lung problems, a real risk - I have also heard that it isn't > as accurate, but cant confirm that. I remain of the opinion that this product has more value as a novelty and lack of needles than it is effective. I cannot believe that any kind of dosing accuracy is possible when one persons' body and respiratory setup is different to the next.
Certainly it would never be any good for a T1 who needs fine dosing control, and I really can't see how it would help an insulin-treated T2 more than an injection of bolus insulin. I saw some initial research findings that takeup of the drug could be as low as 10% in some cases.
Maybe it's one of those products which will just die on the vine after a while, like that Glucowatch thing
Ratty
David - 06 Apr 2006 17:40 GMT > I'm a T2, and as something of a control fanatic I've used Starlix > (nateglenide) to boost insulin production after meals. My diabetologist [quoted text clipped - 4 lines] > > Control freak ah, a willing guinea pig. I love those who dare to tread where hardly anyone else is foolhardy enough to preceed them. You go, freak!
Dave
hilbert - 06 Apr 2006 18:41 GMT Did anyone tell you, Dave, that you are an a.shole ?
This guy wants advice and all you do is to abuse him. Maybe he has tried other things and it did not work for him. No reason for him not to try an FDA approved medication. Of course, there is the risk of a future complication - but it is a personal choice is it not?
David - 06 Apr 2006 18:50 GMT > Did anyone tell you, Dave, that you are an a.shole ? > [quoted text clipped - 3 lines] > is the risk of a future complication - but it is a personal choice is > it not? LOL! Considering the source, I'm not going to take your rude comments to heart.
The only "abuse" is yours of me, and Exubera on unsuspecting patients. Did you know the inhaler is EIGHT inches long?? do you know there's a minimum of 3U dose? Do you know if the dosing will be accurate? do you know the patient still needs to stick themselves with those great big, awful needles [sarcasm] for a basal insulin? Yeah, right; you may have forgotten about that in your haste to bitch about me, rather than discuss the topic at hand with any modicum of intelligence.
do you know ANYTHING of value to add to this thread, or are you content to chastise me as if you were some sort of boorish net cop?
Now run along...
dave
Paul M. Cook - 06 Apr 2006 19:02 GMT > > Did anyone tell you, Dave, that you are an a.shole ? > > [quoted text clipped - 17 lines] > do you know ANYTHING of value to add to this thread, or are you content > to chastise me as if you were some sort of boorish net cop? You could have said all that in your first reply. Instead you chose to launch an attack. So put away the hair shirt already.
Paul
David - 06 Apr 2006 19:07 GMT > You could have said all that in your first reply. Instead you chose to > launch an attack. So put away the hair shirt already. > > Paul Is there an unwritten rule that I need to provide every last bit of information on a topic, in the first post? Do you know how utterly ridiculous you sound??
What do I need to say to have you KF me, twit? There, how about because I called you a twit? I could say more, but I don't want to appear rude.
dave
Paul M. Cook - 06 Apr 2006 19:27 GMT > > You could have said all that in your first reply. Instead you chose to > > launch an attack. So put away the hair shirt already. [quoted text clipped - 4 lines] > information on a topic, in the first post? Do you know how utterly > ridiculous you sound?? Not as ridiculous as you sound when you launch attacks. In fact had you done what I suggested you would have come across as an intelligent, helpful and knowledgeable person. What does that sound so unsavory to you?
> What do I need to say to have you KF me, twit? There, how about because > I called you a twit? I could say more, but I don't want to appear rude. Been called worse. And you already have appeared rude so you can't claim that defense.
Paul
David - 06 Apr 2006 19:31 GMT >>What do I need to say to have you KF me, twit? There, how about because >>I called you a twit? I could say more, but I don't want to appear rude. [quoted text clipped - 3 lines] > > Paul I was being sarcastic, but you, being a dimwit, are unable to process the meaning of my words. Should I use smaller words and include a dictionary for you? I have no need or desire for a "defense" as you ignorantly presumed.
Dave
Paul M. Cook - 06 Apr 2006 20:52 GMT > >>What do I need to say to have you KF me, twit? There, how about because > >>I called you a twit? I could say more, but I don't want to appear rude. [quoted text clipped - 8 lines] > dictionary for you? I have no need or desire for a "defense" as you > ignorantly presumed. Does it get lonely up on that pedestal?
Paul
Loretta Eisenberg - 06 Apr 2006 19:37 GMT gee, David, did I make a mistake. Were you insulting the man.
Loretta
-- In tribute to the United States of America and the State of Israel, two bastions of strength in a world filled with strife and terrorism.
David - 06 Apr 2006 19:51 GMT > gee, David, did I make a mistake. Were you insulting the man. > [quoted text clipped - 4 lines] > of Israel, two bastions of strength in a world filled with strife and > terrorism. NO! read on for more posts.
Dave
David - 06 Apr 2006 19:52 GMT > gee, David, did I make a mistake. Were you insulting the man. > [quoted text clipped - 4 lines] > of Israel, two bastions of strength in a world filled with strife and > terrorism. look at how I address "ozgirl"..."oz". i like to keep it short.
Dave
David - 06 Apr 2006 19:53 GMT > gee, David, did I make a mistake. Were you insulting the man. > [quoted text clipped - 4 lines] > of Israel, two bastions of strength in a world filled with strife and > terrorism. or "LQ" for lizard queen.
(I think I made my point now)
dave
hilbert - 06 Apr 2006 19:11 GMT This is precisely my point. Knowledge does not justify imbecility like you demonstrate.
Instead of calling him a freak, you could have *nicely* told him essentially all the negative things you know about Exubera (I know nothing about it and will freely and gratefully admit you know more) and told him that maybe it was a risk.
You need a good spanking. Maybe your mother did not raise you correctly ?
David - 06 Apr 2006 19:29 GMT > This is precisely my point. Knowledge does not justify imbecility like > you demonstrate. [quoted text clipped - 7 lines] > You need a good spanking. Maybe your mother did not raise > you correctly ? I didn't call him a freak in the usual sense!
He signed his post "control freak", so I shortened it like I shorten many names.
apologize right now or go to hell.
Dave
hilbert - 06 Apr 2006 19:38 GMT Indeed, you are right about that and I apologize.
However, I still stand by my opinion that your first post to the OP was unnecessarily rude. Perhaps a little less rude than I thought before.
You have my apology for my misunderstanding of the "freak" comment. Given that life is too short to waste on bitter acrimony, please do not be offended if I close this chapter and ignore you from now on - if only to attend to more pressing needs (the word "killfile" is very suggestive but too harsh in my opinion).
My best regards.
David - 06 Apr 2006 19:42 GMT > Indeed, you are right about that and I apologize. > [quoted text clipped - 11 lines] > > My best regards. apology accepted. I've no quarrel with someone who admits an honest mistake. KF or not, is fine, too. cheers!
dave
Ma¢k - 07 Apr 2006 19:07 GMT >> Did anyone tell you, Dave, that you are an a.shole ? >> [quoted text clipped - 9 lines] >The only "abuse" is yours of me, and Exubera on unsuspecting patients. >Did you know the inhaler is EIGHT inches long?? are you saying that eight inches has to go up the person's nose?
do you know there's a
>minimum of 3U dose? The OP is a T2, they will most likely use a lot more than 3 Units.
>Do you know if the dosing will be accurate? Do you?
do
>you know the patient still needs to stick themselves with those great >big, awful needles [sarcasm] for a basal insulin? The OP is a type 2 who said they were using starlix before to boost meal time natural insulin production. They were not injecting insulin. So they won't be using a basal insulin as well. And the added insulin will give their beta cells a rest instead of pushing them in the direction of early burn out. which is suspected with starlix and other drugs like it.
Yeah, right; you may
>have forgotten about that in your haste to bitch about me, rather than >discuss the topic at hand with any modicum of intelligence. You didn't discuss the topic at all. you mocked the original poster. Directly breaking a promise you made to the entire group NOT to behave in this manner and to listen to people when they called you on it like hilbert just did, thus breaking your promise a second time with this nasty sniping reply to hilbert.
>do you know ANYTHING of value to add to this thread, or are you content >to chastise me as if you were some sort of boorish net cop? you have not added anything of value to this thread in any post so far. you broke your promise, twice, to the group, not to behave in this manner.
>Now run along... > >dave The story of the scorpion and the frog was about you Dave. You cannot defy your nature.
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Susan - 06 Apr 2006 19:13 GMT > Did anyone tell you, Dave, that you are an a.shole ? Yeah, some have, most just quietly think it as they kill file him, which I highly recommend.
Susan
David - 06 Apr 2006 19:32 GMT > x-no-archive: yes > [quoted text clipped - 4 lines] > > Susan Susan isn't having a good day unless she exhorts others to KF me. Do you know what's funny? I have begged more miscreants to KF me, than she has! You gotta love ignorance!
Dave
Kurt - 06 Apr 2006 20:45 GMT > > x-no-archive: yes > > [quoted text clipped - 7 lines] > you know what's funny? I have begged more miscreants to KF me, than she > has! You gotta love ignorance! Susan is worried that you'll win the "Rudest Poster in ASD" contest and snatch the trophy away from her!!
Best, Kurt
David - 06 Apr 2006 21:35 GMT >>>x-no-archive: yes >>> [quoted text clipped - 14 lines] > Best, > Kurt LOL! She can keep it. My problem is I tell the truth too much! :)
Dave
Loretta Eisenberg - 06 Apr 2006 19:36 GMT Sorry Hilbert, but I have a different thought on Davids response to Exubera. I thought he was praising him for being willing to help science and be a guinea pig. To me, his post was positive.
Loretta
-- In tribute to the United States of America and the State of Israel, two bastions of strength in a world filled with strife and terrorism.
David - 06 Apr 2006 19:39 GMT >> I'm a T2, and as something of a control fanatic I've used Starlix >> (nateglenide) to boost insulin production after meals. My [quoted text clipped - 10 lines] > > Dave FOR THOSE OF YOU WHO ARE AS STUPID AS PAUL M. COOK, WHEN I WROTE, "YOU GO, FREAK", IT WAS A SHORTENED VERSION OF HIS SIGNATURE. GET A CLUE, PEOPLE! IT WAS NOT A RUDENESS!
Dave
Loretta Eisenberg - 06 Apr 2006 19:34 GMT Exubera, I myself wouldnt want to be a guinea pig for inhalable insulin. My case is not bad enough. I dont think it should be for people who already have tight control, but for those who are floundering and cant get it right. It could be of great value to them. My doctor has never mentioned it. I have pretty good control myself
Loretta
-- In tribute to the United States of America and the State of Israel, two bastions of strength in a world filled with strife and terrorism.
Loretta Eisenberg - 06 Apr 2006 19:39 GMT I am sorry , but the man who started this thread called himself control freak. Freak was part of his name as far as I thought. Am I that naive.
Loretta
-- In tribute to the United States of America and the State of Israel, two bastions of strength in a world filled with strife and terrorism.
David - 06 Apr 2006 19:50 GMT > I am sorry , but the man who started this thread called himself control > freak. Freak was part of his name as far as I thought. Am I that [quoted text clipped - 6 lines] > of Israel, two bastions of strength in a world filled with strife and > terrorism. No, Loretta you aren't being naive. I called him freak because of his sig. It wasn't derogatory as hilbert thought.
oh, I posted a big mistake a few minutes ago and I cancelled the post. I wrote that Paul M. Cook was the one who mistook my "freak" mention as rudeness, when it actually hilbert. Hilbert just apologized for his mistake, but I think he also just KF me. what a day! :)
dave
Jenny - 06 Apr 2006 20:44 GMT > I'm a T2, and as something of a control fanatic I've used Starlix > (nateglenide) to boost insulin production after meals. My diabetologist > suggests that I'd make a good First Patient for Exubera. > > Has anyone else heard that from his/her physician? The idea is that this > would reduce postprandial peaks - which, of course, is what do the damage. Do you really want to gamble with your lung tissue? There is no long term safety history with this stuff and there is a real potential that you could develop a permanent reaction in the lung, similar to the skin problems people develop with insulin. If I have a reaction problem, I'd rather it be in the skin, rather than my two, irreplaceable lungs.
Plus, the size of the dose with Exubera only allows for very large steps making it very tough to match your food with the insulin.
Shots are No Big Deal. I've been using insulin for more than 3 months now and the injection is no bigger of an issue than using a lancet for a test. No pain. I can take exactly the amount I need, down to a 1/4 unit, rather than the 3 unit increments of the inhaled stuff.
--Jenny
http://www.phlaunt.com/diabetes Diabetes Info
http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood Sugar Under Control
bj - 06 Apr 2006 20:54 GMT >> I'm a T2, and as something of a control fanatic I've used Starlix >> (nateglenide) to boost insulin production after meals. My diabetologist [quoted text clipped - 17 lines] > No pain. I can take exactly the amount I need, down to a 1/4 unit, rather > than the 3 unit increments of the inhaled stuff. What she said (except I haven't tried shots)
But I'm curious -- are you having problems with Starlix? Maxed Out? Is the Exubera being proposed as an alternative to shots? if so, are you reluctant to use injections? Or is the doctor just looking for someone to be "first"? IOW, do you need to change what you're doing for a *reason*?
Prandin works fine for me, but I'm not averse to trying insulin by injection. bj
Ozgirl - 07 Apr 2006 02:54 GMT > > I'm a T2, and as something of a control fanatic I've used Starlix > > (nateglenide) to boost insulin production after meals. My diabetologist [quoted text clipped - 16 lines] > test. No pain. I can take exactly the amount I need, down to a 1/4 unit, > rather than the 3 unit increments of the inhaled stuff. I think I would be the same. Shots have never bothered me, but I guess there are some people who would prefer anything other than shots.
David - 07 Apr 2006 03:00 GMT >>>I'm a T2, and as something of a control fanatic I've > [quoted text clipped - 57 lines] > but I guess there are some people who would prefer anything > other than shots. Oz, I did a shot tonight because the reservoir in my pump was empty and I had a hot pizza to eat, so I grabbed a syringe and stuck 10 U in my tummy. I pushed it in nice a slow and thought, "how can ANYBODY think that these tiny needles hurt?" I can't even FEEL them, much less feel any pain. I remember when I took 3-4 shots a day, once in a while I'd hit a nerve, and then sure, it would sting for a bit, but the rest of the time there's no sensation during injecting. When I first started on shots in 1978 I'd break out in a sweat before each shot, and it was all in my head. Maybe it's not even an issue of pain; it's just revolting like spiders and snakes?
Dave
Ozgirl - 07 Apr 2006 04:07 GMT > >>>I'm a T2, and as something of a control fanatic I've > > [quoted text clipped - 63 lines] > that these tiny needles hurt?" I can't even FEEL them, much less feel > any pain. The only time I have ever felt shots was when my pregnant tummies were so big and tight I had to inject in the thighs, there was pain there but not enough do more than wince a bit.
I remember when I took 3-4 shots a day, once in a while I'd
> hit a nerve, and then sure, it would sting for a bit, but the rest of > the time there's no sensation during injecting. When I first started on > shots in 1978 I'd break out in a sweat before each shot, and it was all > in my head. Maybe it's not even an issue of pain; it's just revolting > like spiders and snakes? Possible, I have a dreadful fear of spiders. Snakes don't bother me.
Noguru - 07 Apr 2006 04:43 GMT Wow! I felt a bit like the Archduke Ferdinand, although he died starting that war...
My idea - endorsed by my physician, was that T2s who really work hard to suppress postprandial peaks might find Exubera a useful new tool. I have difficulty with Starlix, often use injectable insulin when my food plan demands it, and wanted to experiment with something different. Nothing very dangerous, nothing long term, nothing too wild, just an evaluation... and of course I'd be obligated to keep good data.
Control freak
Alan S - 07 Apr 2006 08:00 GMT >Wow! >I felt a bit like the Archduke Ferdinand, although he died starting that [quoted text clipped - 8 lines] > >Control freak As a control freak - like me - the easiest thing to control is what you eat.
Cheers, Alan, T2, Australia. d&e, metformin 2x500mg
 Signature Everything in Moderation - Except Laughter.
Noguru - 07 Apr 2006 14:58 GMT >> Wow! >> I felt a bit like the Archduke Ferdinand, although he died starting that [quoted text clipped - 14 lines] > Cheers, Alan, T2, Australia. > d&e, metformin 2x500mg I want to eat my cake, and have low bg too.
Chakolate - 07 Apr 2006 19:25 GMT > I want to eat my cake, and have low bg too. At least you're honest.
Chak
 Signature Any sufficiently advanced bureaucracy is indistinguishable from molasses.
Alan S - 07 Apr 2006 23:26 GMT >I want to eat my cake, and have low bg too. It'll work for a while. Maybe for a long while. Maybe not. I try to remove the maybes. That's why I'm also a control freak:-)
Everything has a price.
Cheers, Alan, T2, Australia. d&e, metformin 2x500mg
 Signature Everything in Moderation - Except Laughter.
Jenny - 07 Apr 2006 14:48 GMT > Wow! > I felt a bit like the Archduke Ferdinand, although he died starting that [quoted text clipped - 6 lines] > very dangerous, nothing long term, nothing too wild, just an > evaluation... and of course I'd be obligated to keep good data. Can you handle the fact that the smallest dose available is 3U and that the dosage doesn't increase linearly when you add more?
If you can, then maybe it might work, but you still have to ask yourself how good an idea it is to introduce a growth hormone into your lung tissue.
--Jenny
http://www.phlaunt.com/diabetes Diabetes Info
http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood Sugar Under Control
Jenny - 07 Apr 2006 14:47 GMT > Oz, I did a shot tonight because the reservoir in my pump was empty and > I had a hot pizza to eat, so I grabbed a syringe and stuck 10 U in my > tummy. I pushed it in nice a slow and thought, "how can ANYBODY think > that these tiny needles hurt?" I can't even FEEL them, much less feel > any pain. Yet another couple bits of advice for which I'm very grateful to Dr. Bernstein were:
1. His suggestion that I use a very short needle. My doctor's "diabetes" nurse demonstrated how to inject with a 1 inch needle that would have scared braver folks than me, to say nothing of the fact it could have gone right into my intestines even injecting diagonally . I don't have that much abdominal fat!
To be charitable I have to assume most of the patients for whom they prescribe insulin are very fat. To be uncharitable, based on other things she told me, I'm pretty sure this nurses "diabetes education" such as it was was last updated in 1990. She didn't even know there were short needles on the market.
2. His suggestion that I throw the needle at the injection site "like a dart." The first time I did it, it was so painless I thought it hadn't gone into the skin. It had.
The only problem I have is that I occasionally hit a capillaries close to the surface which results in unsightly bruises which can show when I wear shrinky tops with low cut jeans.
BTW, Dave. I know you are always bashing us non-Type 1s for obsessing about what you think are modestly elevated blood sugars. But after finally getting my blood sugars into 80s and 90s after being mostly 110-140 the difference in my energy level and feeling of wellbeing I'm getting is startling. In fact, I did not realize how lousy I had always until I started feeling good.
Given the nature of my diabetes and the fact that I was testing abnormal even 30 years ago, I'm not sure my blood sugar has EVER been in the normal range. I was getting full blown hypo symptoms with shakes etc for weeks when I first started dropping into the 80s and even now a dose that puts me into the 70s at night will still wake me up and cause a rebound release of glucose that takes me up to 110 or more.
--Jenny
http://www.phlaunt.com/diabetes Diabetes Info
http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood Sugar Under Control
Alexander Arnakis - 07 Apr 2006 15:45 GMT >BTW, Dave. I know you are always bashing us non-Type 1s for obsessing >about what you think are modestly elevated blood sugars. But after >finally getting my blood sugars into 80s and 90s after being mostly >110-140 the difference in my energy level and feeling of wellbeing I'm >getting is startling. In fact, I did not realize how lousy I had always >until I started feeling good. Oh, boy. This truly illustrates the point that "your mileage may vary." When I (a Type 1) am in the 110-140 range, my energy level and feeling of well-being are at the peak. On the other hand, when I'm in the 80's and 90's, I start to get anxious and weak, and feel that a hypo is coming. My target is about 130. Any lower, and I get all sorts of scary hypos.
I just don't understand people who worry about "spikes" in the 140's. Maybe the body reprograms itself based on what you're used to.
Susan - 07 Apr 2006 16:06 GMT >>BTW, Dave. I know you are always bashing us non-Type 1s for obsessing >>about what you think are modestly elevated blood sugars. But after [quoted text clipped - 9 lines] > hypo is coming. My target is about 130. Any lower, and I get all sorts > of scary hypos. It's not at all uncommon for folks who are used to running high to feel crappy with lower, normal numbers until the body adjusts. Pre diagnosis, I used to feel low at 96, now I don't get any bad effects til under 70.
> I just don't understand people who worry about "spikes" in the 140's. > Maybe the body reprograms itself based on what you're used to. Those of us who want to remain below 140 at all times are paying attention to research demonstrating cellular damage at those levels, and beta cell destruction much lower.
Susan
Alexander Arnakis - 08 Apr 2006 06:31 GMT >It's not at all uncommon for folks who are used to running high to feel >crappy with lower, normal numbers until the body adjusts. Pre >diagnosis, I used to feel low at 96, now I don't get any bad effects til >under 70. Question: How did you know what your BG numbers were before you were diagnosed with diabetes? Were you testing just for the heck of it?
>Those of us who want to remain below 140 at all times are paying >attention to research demonstrating cellular damage at those levels, and >beta cell destruction much lower. Well, my beta cells are totally destroyed anyway, so I don't have to worry about that.
It's nice to avoid long-term cellular damage, but my immediate concern is not to be found unconscious from a hypo.
Keep in mind also that simply getting older causes "cellular damage."
Anyway, I've had Type 1 for more than 40 years now with no significant complications other than treatable retinopathy. In the early years, the tight control you're talking about simply wasn't possible, because we didn't have home BG testing, A1c tests, and modern insulin analogues. I probably went about 15 years on one shot a day of NPH.
Jenny - 08 Apr 2006 13:49 GMT Dave wrote:
>What I don't understand is that because 110 is considered a non-DM >number I wonder if you didn't have DM, how you would feel at that >level? :) I have no clue. I doubt I've ever had fasting blood sugars in the normal range. My daughter who is only 23 and exceeding fit already has fasting blood sugars in the mid to upper 90s and higher than normal post meal readings which is one reason the doctor thinks she's inherited the same MODY I seem to have.
One thing you were forgetting when you wrote this message, was that my fasting level of 110 was achieved while eating a LOW CARB diet with per meal carb intake rarely over 20 grams--and often much lower--while maxed out on metformin.
Over the years of reading here, I began to notice that most people with type 2 who began with very high A1cs but then started eating at the carb level I eat at were getting fasting bgs in the normal range, while mine were still in the impaired range and creeping higher.
A very well-conducted study of the pattern of development of type 2 diabetes in people with normal and impaired fasting blood sugar came up with the discovery that type 2 dysfunction doesn't proceed in a linear manner. Fasting blood sugars stay near normal for many years, and then suddenly, within a three year period, massive deterioration takes place--with fasting bgs skyrocketing from near normal to levels like 180 mg/dl.
At that point control becomes far more difficult.
Since I am low carbing, my 110-120 fasting numbers make it likely that eating a more normal diet (which would put my blood sugars into the 200s after ever meal) I'd already be seeing fasting numbers significantly above the diabetic diagnostic range, and that, more over, they'd likely start rocketing much higher.
--Jenny
http://www.phlaunt.com/diabetes Diabetes Info
http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood Sugar Under Control
David - 08 Apr 2006 17:04 GMT > Dave wrote: > >What I don't understand is that because 110 is considered a non-DM [quoted text clipped - 39 lines] > http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood > Sugar Under Control Jenny, I appreciate the reply and info. I think that the sentence of mine that you quoted MIGHT have been misunderstood, IF you inferred that I was suggesting that you aren't diabetic. Is that what you thought I meant? It wasn't. What I meant was that the number itself, 110, shouldn't be causing symptoms if it was a stable number and would be identical to a non diabetic. I never thought for one second that you aren't DM! Hope that clears up any possible confusion. Then again, maybe you weren't inferring that? could you clarify? thanks!
Dave
Jenny - 08 Apr 2006 21:56 GMT I never thought for one second that you
> aren't DM! Hope that clears up any possible confusion. Then again, > maybe you weren't inferring that? could you clarify? thanks! Actually, I thought your question of was a very good one, which is why I was pondering it for a while. A near normal blood sugar and cycles up and down of only 40 mg/dl shouldn't feel as bad as they do.
It probably does have something to do with whatever my oddball genetic diabetes is caused by. My dad. who I seem to have got my diabetes gene from, ate almost no food for as long as I knew him claiming it was the only way he could feel good, so he may have experienced something similar.
One glass of booze will make me feel an exaggerated version of the same kind of yukky and then put me into a sound sleep, too. Always has.
--Jenny
http://www.phlaunt.com/diabetes Diabetes Info
http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood Sugar Under Control
Billie - 07 Apr 2006 19:10 GMT As my bg is beginning to even out since I've been on the pump, I do not feel the "low-effect" until below 70 now. My over-200's are fewer and farther between now, and am using less insulin. I'm also taking Symlin for pp spikes (meaning 200-400 spikes), but my doctor has the high bar at maximum 140 pp. With the illnesses, and the Prednisone, it is a real juggling act for me regardless of what I eat. *Sometimes* it doesn't seem worth the effort (but I know it is :)
Billie T2, pumping MM 715, Humalog Symlin 20u
 Signature bh-wages at swbell.net ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
: Oh, boy. This truly illustrates the point that "your mileage may : vary." When I (a Type 1) am in the 110-140 range, my energy level and [quoted text clipped - 5 lines] : I just don't understand people who worry about "spikes" in the 140's. : Maybe the body reprograms itself based on what you're used to. Alan S - 07 Apr 2006 23:31 GMT >I just don't understand people who worry about "spikes" in the 140's. >Maybe the body reprograms itself based on what you're used to. Think about that. We've had many cases of newby type 2's here giving examples of that. On diagnosis I used to get the shakes under 5(90); these days I see tests at 4(72) and I'm surprised - because I have no symptoms and feel fine.
It may be different for type 1, but you may profit from having a chat with your endo and setting some new targets.
Cheers, Alan, T2, Australia. d&e, metformin 2x500mg
 Signature Everything in Moderation - Except Laughter.
David - 07 Apr 2006 16:52 GMT >> Oz, I did a shot tonight because the reservoir in my pump was empty >> and I had a hot pizza to eat, so I grabbed a syringe and stuck 10 U in [quoted text clipped - 45 lines] > http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood > Sugar Under Control Jenny, I can't possibly argue about how YOU feel at 110.
What I don't understand is that because 110 is considered a non-DM number I wonder if you didn't have DM, how you would feel at that level? :)
Dave
Billie - 07 Apr 2006 18:58 GMT Jenny, my endo has confirmed that my GGT in 71 was a firm dx, but it was missed at the time (200+ reading) because of the sudden drop in the 40's, with only the RH being noted. Therefore, I went untreated until 2001, and amassed multiple complications. We were in the Air Force with doctors changing every year or two, without continuity of care. :(
Billie
 Signature bh-wages at swbell.net ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
: Given the nature of my diabetes and the fact that I was testing abnormal : even 30 years ago, I'm not sure my blood sugar has EVER been in the [quoted text clipped - 5 lines] : --Jenny.htm Get Your Blood : Sugar Under Control Jenny - 07 Apr 2006 20:51 GMT > Jenny, my endo has confirmed that my GGT in 71 was a firm dx, but it was missed at the time > (200+ reading) because of the sudden drop in the 40's, with only the RH being noted. Therefore, > I went untreated until 2001, and amassed multiple complications. We were in the Air Force with > doctors changing every year or two, without continuity of care. :( What a shame!
I wish I knew what the actual numbers were for my GTT in the 70s. The doctor just told me that my blood sugar was very hypoglycemic and officially "pre-diabetic" but back then I didn't know enough to ask what that meant. I was in grad school at the time and when I finally got to where I had medical insurance my new doctor told me that hypoglycemia was a "fashionable diagnosis" that didn't mean anything and to ignore it.
Two diabetic pregnancies later they were still telling me I had nothing to worry about because I wasn't fat.
--Jenny
http://www.phlaunt.com/diabetes Diabetes Info
http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood Sugar Under Control
Ozgirl - 07 Apr 2006 21:45 GMT >> Oz, I did a shot tonight because the reservoir in my pump was empty >> and I had a hot pizza to eat, so I grabbed a syringe and stuck 10 U
>> in my tummy. I pushed it in nice a slow and thought, "how can
>> ANYBODY think that these tiny needles hurt?" I can't even FEEL
>> them, much less feel any pain. > [quoted text clipped - 3 lines] > 1. His suggestion that I use a very short needle. My doctor's > "diabetes" nurse demonstrated how to inject with a 1 inch needle that
> would have scared braver folks than me, to say nothing of the fact it
> could have gone right into my intestines even injecting diagonally .
> I don't have that much abdominal fat! I always shot at an angle. I wasn't fat but having had kids I was able to pick up a good bit of loose skin. The only pain was in latter months with the belly so tight. Shooting in the thighs was way bad ;)
Jenny - 07 Apr 2006 14:33 GMT > I think I would be the same. Shots have never bothered me, > but I guess there are some people who would prefer anything > other than shots. Including, of course, rotten control.
The only way bolus insulin makes sense is if you can match it to the food intake. Inhaled insulin is bolus insulin! If you can't match it to your food, you will get no significant control or you'll have to eat a lot of extra carbohydrate to keep from going hypo which will cause weight gain.
This stuff costs something like 3 times as much as the expensive injectable insulins, driving up health care expenses, while NOT improving health and quite possibly leading to a long slow death by suffocation.
The FDA has shown quite clearly over the past few years that it is the servant of the drug companies and will approve drugs without demanding the kinds of safety testing that prevent massive disasters.
--Jenny
http://www.phlaunt.com/diabetes Diabetes Info
http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood Sugar Under Control
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