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Medical Forum / Diseases and Disorders / Diabetes / March 2006Can exercise and weight loss increase insulin resistance, in the short term?
I know this sounds like a bizarre question but I've been wondering about a few aspects of the exercise/weight loss/insulin resistance equation. When you lose fat, it has to get mobilized to be burned which, I presume, would increase the amounts of free fatty acids floating around in the bloodstream. Since FFAs have a negative impact on pancreas response and insulin resistance, could the mobilization of all that fat actually make bg numbers get worse while the weight loss is occurring? Also, exercise can make the liver dump glucose. If you don't exercise long enough to blot it all up, or if the "blotting" isn't working well enough, you could provoke an insulin response to pick it all up. High levels of insulin response increases insulin resistance, right? Also stress - if stress can increase IR, could exercise and weight loss cause enough stress hormones (cortisol) to increase the IR until the stress goes away? The reason I ask all this is because I've been doing everything right (exercise, lost 27 lbs) yet my tolerance for even minor amounts of carbohydrates seems to be decreasing, rather than increasing, and my numbers are getting worse. Any thoughts on this would be welcome as I try to figure this out (and as I beg for an appt with an endo). LQ > I know this sounds like a bizarre question but I've been wondering > about a few aspects of the exercise/weight loss/insulin resistance [quoted text clipped - 23 lines] > Any thoughts on this would be welcome as I try to figure this out (and > as I beg for an appt with an endo). Exercise and low carb will reduce hyperinsulinemia and IR eventually, if not quickly enough to satisfy you. :-) Keep exercising, keep carbs moderate to low, and stop thinking so damned much. It's too soon to know what your results will be; this is a process, not an instant reward for good behavior. And get that endo appt, 'kay? Susan All I'm trying to do is try to figure out if there's an optimal level of exercise and weight loss where it's enough to drop IR but not so much to increase it because of stress and a too-fast release of FFAs. If I'm overdoing it and it's making my symptoms worse then I want to know. I went into this great guns thinking that the faster I got the weight off and got in shape the sooner the symptoms would be gone. Unfortunately I feel worse now and I'm trying to understand why. It's very easy to say "stop thinking so much" but being up at 3 AM every night I have a LOT of time to think since sleeping is impossible once the shakes start. LQ > All I'm trying to do is try to figure out if there's an optimal level > of exercise and weight loss where it's enough to drop IR but not so [quoted text clipped - 9 lines] > every night I have a LOT of time to think since sleeping is impossible > once the shakes start. You know I've been there and I understand. I also tend toward extreme attention to detail, bordering on obessive at times, and wanting to control what's happening to me NOW, so I am not dismissing your concerns, I'm just offering the benefit of my experience and my best advice. There are times when uncertainty is the only answer we get, and we have to be okay with that while we're on the way to other, slower to develop answers. Sorry if you felt dismissed, that's not my intention. Susan Sorry if I came across as snappy, I do really appreciate all the help you've given me. I'm just right on the ragged edge of completely flipping out since I haven't slept well in nearly 2 months. At this point I don't even care much about the bg numbers, the reason I worry about them is because from the numbers come my symptoms and I'm finding the symptoms both intolerable and unmanageable. For instance, the "6 small meals a day" concept would be great except for the fact that I shake after all of them so eating more frequently makes me shake more often. What else can I do, I've done everything I can and STILL feel like sh.t! And it's not like this has been going on a week or two, this is week 7 with no letup in sight. At this point full blown diabetes would almost be a relief as then my BG would at least be stable. LQ > Sorry if I came across as snappy, I do really appreciate all the help > you've given me. > I'm just right on the ragged edge of completely flipping out since I > haven't slept well in nearly 2 months. I get that. > At this point I don't even care much about the bg numbers, the reason I > worry about them is because from the numbers come my symptoms and I'm [quoted text clipped - 4 lines] > can and STILL feel like sh.t! And it's not like this has been going on > a week or two, this is week 7 with no letup in sight. Some stuff has improved, though, right? You can sleep a little longer without waking up when you have protein. Weren't you waking a lot more often before? There is letup occurring. You also have to consider that the wakefulness and shakes can be peri related, and may not be fixed completely by diet and exercise. > At this point full blown diabetes would almost be a relief as then my > BG would at least be stable. Not necessarily. Don't buy trouble; you're in a state of flux and you need some good medical evaluation and guidance. Becoming diabetic isn't your best option, trust me. Susan >I know this sounds like a bizarre question but I've been wondering >about a few aspects of the exercise/weight loss/insulin resistance [quoted text clipped - 25 lines] > >LQ Hi LQ, I have never heard of anything but positive benefit for a T2 resulting from exercise and weight control. Having said that, I would caution that if there is ketoacidosis present, or even very high levels of BG (over 250), I would say that a person ought to consult with their doctor, before entering upon a sustained exercise program. In my own case, the outcome of a coordinated exercise program and diet change was a stupendous improvement of the numbers, across the board... I am sure I am not the exception. As an initial target, I would suggest a FBG of less than 120.. If you have already achieved that, ratchet it down to less than 100.... Remember, exercise, watch the carbs, and test, test, test. If you are a nascent T1, none of that will work... You will ultimately need insulin. I always did like Zena! :-) Wishing you all the best, Will, T2 :: On 29 Mar 2006 06:41:48 -0800, "LizardQueen" <GreenRaven@att.net> :: wrote: [quoted text clipped - 52 lines] :: :: Will, T2 She's not diabetic. >:: On 29 Mar 2006 06:41:48 -0800, "LizardQueen" <GreenRaven@att.net> >:: wrote: [quoted text clipped - 54 lines] > >She's not diabetic. Hi Roger, if you meant LQ is not diabetic, I guess that could be true, but she obviously is having problems, and she is posting in this group looking for advice and suggestions. If you meant Zena is not diabetic, I guess we'll have to ask Lucy Lawless about that. :-) The reason I mentioned Zena is because LQ described herself as somewhat resembling Zena.... Will, T2 :: On Wed, 29 Mar 2006 21:19:53 -0500, "Roger Zoul" :: <rogerzoul2@hotmail.com> wrote: [quoted text clipped - 63 lines] :: true, but she obviously is having problems, and she is posting in :: this group looking for advice and suggestions. From the many posts of her's that I've read, she seem so to be suffering from RH, and isn't yet diabetic, but wants to head it off. I don't think she has the high FBG that you mentioned or the high BG levels either. But she apparently suffers from quick drops that seem to make her feel bad a lot. I can't help but feel for her. I was just trying you some info about her, not being critical. :: If you meant Zena is not diabetic, I guess we'll have to ask Lucy :: Lawless about that. :-) The reason I mentioned Zena is because LQ :: described herself as somewhat resembling Zena.... I like the Zena types! :) ps...well, actually, I like most types...only a few 'types' that don't attract me...well.... "Also, exercise can make the liver dump glucose. If you don't exercise long enough to blot it all up, or if the "blotting" isn't working well enough, you could provoke an insulin response to pick it all up. High levels of insulin response increases insulin resistance, right? " Actually your liver accounts for only 20% of your capacity to store gluocse. The other 80% is in your muscles. So when you use what is in your muscles and draw upon the sugar in your blood, by the time the liver dumps sugar, your muscles will be looking to replenish their stores, over the next 24 hours approximately. And their stores are much more than the liver can dump. Any increase in blood sugar is thus temporary and you would not have high levels of insulin for more than a very short period unless you did something else to provoke it. Morris |
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