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Medical Forum / Diseases and Disorders / Diabetes / March 2006

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Speaking of family medical history.........

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naneklund@aol.com - 28 Mar 2006 16:25 GMT
When diagnosed in 1990 I thought the only other Type 2 diabetic in my
family was my mother's aunt (who eventually died of it in the 1930s).
Last summer I was invited to a "reunion" of my father's side, in
Montana, all descendents of a Swedish immigrant in 1862.  I'd lost
touch with that side (no one closer than a second cousin) for almost 60
years.
Wow.......every third person was diabetic!
(Slight exaggeration there.......but it seemed like that many!
Testers all over, careful eaters all over - except for the beer.  I
think Swedes have a special dispensation for beer.)
Anyway, it goes to support the genetic tie to the disease - and I also
noticed that the physical appearance was........stocky.  Also
inherited.  Not necessarily fat, although there were a few fatties, but
a thick build.  Tall, heavy bones, wide shoulders, wide hips.
Just an interesting sidelight and one that more of us should explore.
I told my doctor when I got back and he (guess what HIS ancestry is?)
said, "of course".  
Nan, Type 2
Alan S - 29 Mar 2006 00:41 GMT
>When diagnosed in 1990 I thought the only other Type 2 diabetic in my
>family was my mother's aunt (who eventually died of it in the 1930s).
[quoted text clipped - 14 lines]
>said, "of course".  
>Nan, Type 2

I wasn't aware of any in my family. Then, I found my Aunt
was a "secret" diabetic. You know - something that wasn't
talked about until I turned up with my meter.

Then I realised that old photos of my maternal grandfather
looked like me pre-dx - from the bald top (not relevant I
know - but also genetic) to the well-rounded middle. He went
at 74, although Gran went on until 102.

Now, my cousin, daughter of that aunt, has been diagnosed.
and lately I hear indirectly of other cousins who "have to
watch their sugars".

So, we've found the cure. Change your parents:-)

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
Signature

Everything in Moderation - Except Laughter.

Opal - 29 Mar 2006 04:32 GMT
> When diagnosed in 1990 I thought the only other Type 2 diabetic in my
> family was my mother's aunt (who eventually died of it in the 1930s).
[quoted text clipped - 3 lines]
> years.
> Wow.......every third person was diabetic!

heh    I've come to the conclusion that it is the odd numbered family
members who get it.

I am the youngest of 7 kids.  However, I was also the FIRST in my family to
be diagnosed T2, back when I was 26. (my siblings at the time ranged from 46
down to 35).   2 of my sisters had since been diagnosed, and I found out
today a 3rd one was, too.  But, get this.... of us kids, it was numbers 1,
3, 5 and 7 (me) who have it.   2, 4 and 6 are fine.

And, following the genetics, we're ALL "stocky and/or heavily built".   My
dad was overweight most of his life (he died of cancer at age 56), but my
mom was no more than 130 lbs (at 9 months pregnant) until she retired at
which time she started to gain.  She is up to 165 pounds at age 76, very
apple-shaped, but still isn't diabetic.  To my knowledge, there STILL isn't
any diabetes anywhere else in my family. (and we have LOTS of cousins,
second cousins, etc, plenty of whom are stocky and/or overweight, too)

------

Kelly, T2, yada, yada.
louisejoi - 29 Mar 2006 13:54 GMT
>> Anyway, it goes to support the genetic tie to the disease - and I also
> noticed that the physical appearance was........stocky.  Also
> inherited.  Not necessarily fat, although there were a few fatties, but
> a thick build.  Tall, heavy bones, wide shoulders, wide hips.
> Just an interesting sidelight and one that more of us should explore.

Same in my family.  Most of us first cousins have diabetes and all of us are
"stocky" and most of us when diagnosed were probably 10-20 pounds
overweight.  Mind you, all of the  men are over 6 ft, so nobody who was
diagnosed was grossly obese.  However the one first cousin who is grossly
obese, probably by at least 100 pounds has not been diagnosed.  Now she is
the youngest, but most of us had been diagnosed by her age.  Time will
tell...maybe she just got lucky.

Signature

Best wishes,
Louise

Type 2 since 2000
Controlling by exercise and diet
and metformin!

W. Baker - 29 Mar 2006 23:15 GMT
: When diagnosed in 1990 I thought the only other Type 2 diabetic in my
: family was my mother's aunt (who eventually died of it in the 1930s).
[quoted text clipped - 14 lines]
: said, "of course".  
: Nan, Type 2

Nan,

Nce to see you posting now.  I thought you would not be able to get yur
head up from the tax forms:-)  

iInteresting about your family.  I still have not found anyone o neither
side who is diabetic.  Only the wife of a second cousin and that doesn't
count:-)  My D-I-L, both of whose parents are diabetic, has "officially"
been diagnosed adn it sruggling to lower her bg's while trying to folow
her dieticians recomendtions(60 carbs at dinner, including a class of skim
milk).  I did send her jennifer's wonderful post.  

Well, enough chit-chat- get that nose back to the grindstone:-)

Wendy
Jenny - 30 Mar 2006 14:36 GMT
> iInteresting about your family.  I still have not found anyone o neither
> side who is diabetic.  

My researches into the history of diabetes diagnosis came up with the
information that before the advent of the first oral drugs, doctors
often did not diagnose type 2 diabetes until it was very severe. Even 15
years ago a fasting blood sugar of 135 mg/dl would have been treated as
normal.

So it is quite possible that your relatives with diabetes never got a
formal diagnosis.

Is there a strong history of heart attacks at relatively young ages
(50-65)?  Kidney failure?

--Jenny

http://www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
naneklund@aol.com - 30 Mar 2006 16:42 GMT
My parents (neither diabetic) both died of heart failute, my mother at
74 and my dad, the stocky Swede (6'2" and 160 to 220 pounds at various
times) at 77.  No kidney failures.
The second cousins in Montana had a lot of over-70 members and I didn't
hear of any early deaths.
Nan, Type 2
W. Baker - 30 Mar 2006 18:40 GMT
: > iInteresting about your family.  I still have not found anyone o neither
: > side who is diabetic.  

: My researches into the history of diabetes diagnosis came up with the
: information that before the advent of the first oral drugs, doctors
: often did not diagnose type 2 diabetes until it was very severe. Even 15
: years ago a fasting blood sugar of 135 mg/dl would have been treated as
: normal.

: So it is quite possible that your relatives with diabetes never got a
: formal diagnosis.

: Is there a strong history of heart attacks at relatively young ages
: (50-65)?  Kidney failure?

: --Jenny

No there is no history of that.  there were heart attacks ad strokes among
some of the men, but these were generally in their 70's, also some high
plood pressure and the occasionalheart attack, also reletively late in
life.  There, also was not a lot of obesity among theolder folks, which
may, well, be a factor.  No one was skinny, but all of reasonable size.  
My brother, who also was heavy, never developed either diabetes of a heart
condition.  He died at 75, just two yers ago, of a fall down his cellar
stairs, comething I still am dealing with.  

Something I have been ewanting to ask, particularly you, Jenny, as I know
you wer on precose, My DIL, recently diagnosed was put o Slyct, which she
said was to prevent digestion of carbs.  I had never heard of it, so I
wondered what yu know about it and its effectivelness.  she has
subsequently been put on metforming, which I am pleased with adn she is
losign weight and actually listened to me about testing after meals to
find out whar she can eat.  I have. also, sent her ennifer's post.  Her
dieician has put her on one of those 200 carbs a day diets, with a glass
of skim milk at every mel.  (she is lactose intolerant and very kosher!)
She finds she cannot eat that man  carbs at all.  

Wendy
W. Baker - 30 Mar 2006 23:36 GMT
: Something I have been ewanting to ask, particularly you, Jenny, as I know
: you wer on precose, My DIL, recently diagnosed was put o Slyct, which she
: said was to prevent digestion of carbs.  I had never heard of it, so I

Anoeher oops from me.  That should read Glycet for her med.

Wendy-still learning to type and read
Jenny - 31 Mar 2006 00:35 GMT
> Something I have been ewanting to ask, particularly you, Jenny, as I know
> you wer on precose, My DIL, recently diagnosed was put o Slyct, which she
> said was to prevent digestion of carbs.

First of all, let me express my condolences on your brother's tragic
death. Such a sad thing to survive a beloved sibling!

Now, back to your question:

I'm assuming you meant Glycet. All I know about it is that it is another
drug that as always listed along with Precose as Alpha-glucosidase
inhibitor.

I used Precose for several years. My experience with it was this:

1. Used once a day it allowed me to up my carbs by another 15-20 grams,
max, without serious spiking. During the year when I stopped low carbing
(and packed on all the weight) taking Precose with each meal stopped the
weight gain cold, which was much appreciated.

Throughout the time I was using it, I had enough of a second phase
response that if I could postpone the spike, the second phase response
would mop up the delayed carbs.

2. When my blood sugar worsened significantly last spring, after the
doctor took me off the Diovan, I started seeing the spike which had been
delayed showing up a couple hours later.

So I conclude this is a drug that works best for people who still have a
 decent second phase response.

SIDE EFFECTS:

1. Horrible gas. I found the gas was negligible if I only used it once a
day. I started with the 25 mg dose and worked up to the 100 mg dose for
that reason.  But if I used it a couple times a day, eventually the gas
would be a big problem.

  I have. also, sent her ennifer's post.  Her
> dieician has put her on one of those 200 carbs a day diets, with a glass
> of skim milk at every mel.  (she is lactose intolerant and very kosher!)

OH, these dietitians! Has a single one of them ever tested their blood
sugar after a meal?

Hopefully she'll use her head. I don't think I ever ate 200 grams a day
after my mid 30s even when I was eating a so-called normal diet. That's
a lot of carb for a small middle aged lady.

--Jenny

http://www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
Nicky - 31 Mar 2006 08:54 GMT
> Her
> dieician has put her on one of those 200 carbs a day diets, with a glass
> of skim milk at every meal.  (she is lactose intolerant and very kosher!)

Even apart from the carbs stupidity, what on earth is the point in
prescribing a diet that doesn't fit in the patient's belief system? Sheesh!

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

Susan Adair - 31 Mar 2006 16:06 GMT
I'm amazed at the pattern of fairly long-lived families in this little
sub-sample. I'm 59; my parents are 90 and 83.  They have health
problems but mostly related to bone and muscle.  My dad has severe
hearing loss - probably related to noise in WW2 - he packed parachutes
for guys on bombers - and his eyesight is very poor, but he's the one
who has normal bg  whatever he eats. He has breathing difficulty from
time to time, but he was a heavy smoker until he was 50 when he stopped
cold.  My mother's chief problems are hip and knee - both knees and one
hip have been replaced.  She has osteoarthritis, but no heart or kidney
problems.   Older relatives have mostly lasted into their 80s unless
they had specific dieseases, like leukemia, or heavy smoking.

Since T2 is clearly a genetic disease that takes time to show up the
genes are passed on easily, but some sets of them seem to allow for a
long delay - long enough to let people live their lives without
diagnosis.  This may be changing as the diagnosis levels are reduced
and GPs get clued in to early signs of trouble.  On the other hand, I
still think the reason nothing really showed in my mother's family is
that their lives were active and their diets better.  I - and my
siblings - have much more sedentary lives than our parents and
grandparents, and we eat a lot more commercially prepared foods, with
much more bread and starch than I remember from my childhood.

Susan Adair
bj - 30 Mar 2006 17:26 GMT
>   I still have not found anyone o neither side who is diabetic.  Only the
> wife of a second cousin and that doesn't count:-)

Me neither (though I think a couple of my relatives are on their way....) --
but there was the husband of my father's cousin.
:-)

> My researches into the history of diabetes diagnosis came up with the
> information that before the advent of the first oral drugs, doctors
[quoted text clipped - 7 lines]
> Is there a strong history of heart attacks at relatively young ages
> (50-65)?  Kidney failure?

Nope. No heart attacks. No kidney failure.
No amputations or blindness.
A lot of "old age" general wearing out.
Most of my relatives lived longer than I expect to!
My dad died at 87 & my mom is going strong at 85.
:-)
bj
 
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