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Medical Forum / Diseases and Disorders / Diabetes / March 2006

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Dairy and calcium consumption and inverse relation to colon cancer risk

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Susan - 27 Mar 2006 19:48 GMT
http://www.medscape.com/viewarticle/528420?sssdmh=dm1.186557&src=nldne

"    * Milk was the dairy product most associated with a reduced risk
for colorectal cancer. Subjects who consumed more than 1.5 glasses of
milk per day had a 33% lower risk for colorectal cancer vs participants
who drank less than 2 glasses per week. The benefit of milk appeared
regardless of milk fat content. The authors note that cheese and yogurt
may not have improved colorectal cancer risk on their own because these
foods accounted for a much smaller fraction of dietary calcium
consumption compared with milk.

Pearls for Practice

    * A pooled analysis of prospective trials demonstrated that
consumption of both dairy products and calcium consumption had an
inverse relationship on the risk for colorectal cancer. The benefits of
milk consumption were limited to cancer of the distal colon and rectum.
    * The current study found that dietary consumption of both calcium
and dairy products reduces the overall incidence of colorectal cancer in
men, with no significantly different effects on specific colonic sites
of cancer. Milk was the most effective dairy product in reducing the
risk for colorectal cancer, and there was little added preventive
benefit above a daily intake of 1400 mg of dietary calcium per day."

Note, fat content did not alter risk.

Susan
Quentin Grady - 27 Mar 2006 23:27 GMT
G'day G'day Susan,

Thanks for posting.  Colorectal cancer is one cancer that is thought
to have a high risk associated with dietary factors.  The problem has
been that each time excellent sounding hypotheses have been advanced
to warrant large scale INTERVENTION trials the hot contenders for
reducing the risk have not worked.  The situation regarding fibre
intake was most embarrassing for its proponents.  I wish all those
working in this field the best of luck in choosing the right specifics
to trial.  We all need them to find a satisfactory working model to
make intelligent food choices.  

Best wishes,
Quentin.

This post not CC'd by email
On Mon, 27 Mar 2006 13:48:15 -0500, Susan <nevermind@nomail.com>
wrote:

>x-no-archive: yes
>
[quoted text clipped - 25 lines]
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>Susan

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Susan - 28 Mar 2006 00:06 GMT
> G'day G'day Susan,
>
[quoted text clipped - 7 lines]
> to trial.  We all need them to find a satisfactory working model to
> make intelligent food choices.  

I think the confounding results in the fiber trials may've had to do
with the fact that they didn't control for the source and how
insulinogenic the whole diet was.  Where fiber was alleged to be
protective, it may've simply lowered the total metabolizable carb load
to produce the effect.  I would guess that if the fiber came from more
leafy stuff and less starch, all the phytonutrients might've been
protective against ca.

In checking Medline, a few cancers leap out as having tight relations
with hyperinsulinemia.  Off the top of my head, breast, colon, prostate,
ovarian and pancreatic cancers.

Forest, trees, all that.  :-/

Susan
 
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