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Medical Forum / Diseases and Disorders / Diabetes / March 2006

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Things are getting worse, rather than better

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LizardQueen - 05 Mar 2006 14:31 GMT
I don't know what's going on, I'm shaking around the clock now.  Got
almost no sleep last night because of bouts of the shakes plus night
sweats (could be female hormones but who knows).

Snacks don't seem to be enough to stop the shakes.  And the shakes are
not correlating to the meter as much. I'm getting them when I first get
up in the AM not even after eating.

If I cut down the carbs I feel worse. If I raise them my bg goes up.
I'm at a loss as to how to make myself feel better until I can get in
to the docs (Wednesday).

The best I felt was Friday at work. It was busy there so ate a can of
soup for lunch (all I had around) that had 40 g carbs in it (and fast
ones at that).  I spiked at 162 at a half hour (could feel the heat and
dizziness so I tested) then dropped 40 pts 10 minutes after that, went
up a little at the 2 hour (127), then dropped again, but then my bg was
ok the rest of the afternoon and my anxiety went away.

I'm wondering if the relative lack of carbs compared to my previous
life is screwing up the serotonin in my brain.

This is horrible, I can't continue like this.

LQ
Cheri - 05 Mar 2006 15:29 GMT
I wish I had some advice to give you but I don't since so many foods
affect us differently. I have very little tolerance for fast acting
carbs and can go quite high fairly fast. I don't get shaky when I'm
high, but I do get shaky when I'm low. Hopefully, when you see the doc
on Wednesday you'll get some answers.

--
Cheri
Take the best, and disregard the rest.

LizardQueen wrote in message
<1141569108.119287.227240@t39g2000cwt.googlegroups.com>...
>I don't know what's going on, I'm shaking around the clock now.  Got
>almost no sleep last night because of bouts of the shakes plus night
[quoted text clipped - 21 lines]
>
>LQ
Susan - 05 Mar 2006 15:36 GMT
> I don't know what's going on, I'm shaking around the clock now.  Got
> almost no sleep last night because of bouts of the shakes plus night
> sweats (could be female hormones but who knows).

Yes, it could be peri.  Non stop trembling, along with other stuff
(insomnia, waking with chills and sweats, and other stuff) accompanied
onset for me.

You should be evaluated medically, maintain a diet you know to be healthy.

Susan
LizardQueen - 05 Mar 2006 16:11 GMT
I'm pretty sure it's a serotonin thing (whether from the sudden lack of
dietary starch or the female hormone thing, I don't know).

In desperation this AM I emptied half a capsule of 50 mg 5-HTP (had it
around from the last time I tried going off the Zoloft) into a glass of
water and drank it. 1 hour later the shakes have mostly stopped.
I don't feel great but better than I have for the last 24 hours.

I don't like 5 HTP and don't think it's safe (it's an intermediary
metabolite of the l-tryptophan --> serotonin process that usually isn't
found on this side of the blood/brain barrier) but as an experiment it
was an interesting one and that little bit is unlikely to hurt me.

I just hope Doc 2.0 knows his stuff......

This all makes sense in the abstract - high carbs = high levels of
tryptophan entering brain, raises serotonin. Sudden low carbs = lower
levels of brain serotonin, brain gets pissed off because it's used to
the high levels and I start shaking.

I'm paying a heavy price for years of self-medicating with starch,
apparently.

Thanks for listening.
LQ
Susan - 05 Mar 2006 16:21 GMT
> I'm pretty sure it's a serotonin thing (whether from the sudden lack of
> dietary starch or the female hormone thing, I don't know).

I don't know how you can be sure; you have so many things going on; bg
issues, perimenopause and extreme anxiety.  All can produce your symptoms.

> In desperation this AM I emptied half a capsule of 50 mg 5-HTP (had it
> around from the last time I tried going off the Zoloft) into a glass of
[quoted text clipped - 5 lines]
> found on this side of the blood/brain barrier) but as an experiment it
> was an interesting one and that little bit is unlikely to hurt me.

It's very safe, from all I've read, as a serotonin precursor.  I'm not
sure it's safe to add it to an rx SSRI, however.

> I just hope Doc 2.0 knows his stuff......
>
[quoted text clipped - 8 lines]
> Thanks for listening.
> LQ

Good luck.

Susan
Jennifer - 05 Mar 2006 17:27 GMT
It could be many things.

It may have nothing to do with carbs or diabetes.

See the doctor.

Jennifer

> I'm pretty sure it's a serotonin thing (whether from the sudden lack of
> dietary starch or the female hormone thing, I don't know).
[quoted text clipped - 21 lines]
> Thanks for listening.
> LQ
Alan S - 05 Mar 2006 23:28 GMT
>It could be many things.
>
[quoted text clipped - 3 lines]
>
>Jennifer

Beat me to it. I wouldn't wait until Wednesday.

And if the doc doesn't have the answer - ask advice on which
specialist the doc thinks you should see.

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
Signature

Everything in Moderation - Except Laughter.

Nicky - 05 Mar 2006 18:43 GMT
> Thanks for listening.

Keep talking, if it helps! It sounds awful, you have my full sympathy. The
only thing I can think of is chocolate and other serotonin stimulators!

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

Ozgirl - 05 Mar 2006 20:29 GMT
> I'm pretty sure it's a serotonin thing (whether from the sudden lack
> of dietary starch or the female hormone thing, I don't
know).

> In desperation this AM I emptied half a capsule of 50 mg 5-HTP (had it
> around from the last time I tried going off the Zoloft) into a glass
> of water and drank it. 1 hour later the shakes have mostly
stopped.
> I don't feel great but better than I have for the last 24 hours.
>
> I don't like 5 HTP and don't think it's safe (it's an intermediary
> metabolite of the l-tryptophan --> serotonin process that usually
> isn't found on this side of the blood/brain barrier) but
as an
> experiment it was an interesting one and that little bit
is unlikely
> to hurt me.
>
[quoted text clipped - 7 lines]
> I'm paying a heavy price for years of self-medicating with starch,
> apparently.

How often are you eating? When I first became symptomatic I
was having to eat half hourly, that changed after a while
but it made life a heck of a lot easier while I was doing it
ont the half hour.
LizardQueen - 05 Mar 2006 22:36 GMT
Every 2 1/2, which I think is ok. Bg has been stable as a rock doing
that with what I'm eating. As I get near the eating time I get a
different feeling which is the "running out of gas" feeling.
It's so damn hard to explain and sounds really stupid but there have
been 3 or 4 different kinds of shaking I've gotten from this.  The
"omigod I'm going to climb out of my skin" anxiety went away after 5
days, then I got the fast "blood sugar tanking" one after eating
something too carby but I think I've licked that one by figuring out
the menu, then there's the "running out of gas" feeling that I still
get before I need to eat again, but this new bit is non-meter-or-food
correlated.  I'll have it before and after I eat without eating making
a difference in it.

Maybe this is still the aftershocks of cutting down the carbs, or it
could be the lovely perimenopause thing that I am squarely in. Who
knows at this point.

I agree with all you guys, I need to get this looked at by a competent
doc. I just hope the one that I have an appt with on Wed is competent,
unlike my current PCP.

Who knew that eating so well could make me feel so shitty? ;)

It's better this PM, I managed to get a nap in after the AM's 5-HTP
experiment.  I've also been trying to eat more stuff that has a lot of
tryptophan in it (cottage cheese was part of lunch and snack) which may
be playing a part.

And no worries, I won't be taking any more of the HTP, I know it
doesn't mix with SSRIs.

Thanks for being here, sorry if I sound like a nutcase, I just feel
like crap.
LQ

P.S. on the bright side, I'm 12 lbs lighter today, without even really
trying to lose it.
Susan - 05 Mar 2006 23:31 GMT
> Every 2 1/2, which I think is ok. Bg has been stable as a rock doing
> that with what I'm eating. As I get near the eating time I get a
[quoted text clipped - 12 lines]
> could be the lovely perimenopause thing that I am squarely in. Who
> knows at this point.

I recall that 1.5 - 2 hours was my shaky time til I lost the
hypoglycemia.  Now it's more like 5 or 6 hours til I realize i NEED to eat.

> I agree with all you guys, I need to get this looked at by a competent
> doc. I just hope the one that I have an appt with on Wed is competent,
> unlike my current PCP.

I hope so, too.

> Who knew that eating so well could make me feel so shitty? ;)

Who knew that recovering from eating shitty would take this long!?  ;-)

> It's better this PM, I managed to get a nap in after the AM's 5-HTP
> experiment.  I've also been trying to eat more stuff that has a lot of
[quoted text clipped - 10 lines]
> P.S. on the bright side, I'm 12 lbs lighter today, without even really
> trying to lose it.

You're not sounding nutty, just overwhelmed and anxious.

Susan
Chakolate - 05 Mar 2006 21:22 GMT
"LizardQueen" <GreenRaven@att.net> wrote in news:1141575085.292961.76180
@v46g2000cwv.googlegroups.com:

> I don't like 5 HTP and don't think it's safe (it's an intermediary
> metabolite of the l-tryptophan --> serotonin process that usually isn't
> found on this side of the blood/brain barrier) but as an experiment it
> was an interesting one and that little bit is unlikely to hurt me.

I've been using 5-HTP, 300 mg/day, for nearly a year now, and I love it.  
Combined with L-tyrosine, it has improved and stabilized my mood and
improved my short-term memory and focus tremendously.

Chak

Signature

In science, 'fact' can only mean 'confirmed to such a degree that it
would be perverse to withhold provisional assent.' I suppose that apples
might start to rise tomorrow, but the possibility does not merit equal
time in physics classrooms.
 --Stephen Jay Gould

Mr. Gantlet - 05 Mar 2006 16:41 GMT
please see a  doctor if you didn't trust the one you worked with see
another.
and another and another and another until you find one you trust.
if you don't find a doctor that agrees with what you think your treatment
should be
perhaps it is time to rethink your treatment.

Signature

Tom
Exercise Today = Life Tomorrow
Information you can trust from the diabetes experts...
Your American Diabetes Association
http://www.diabetes.org/home.jsp
the American Diabetes Association's Message Boards
http://community.diabetes.org/n/pfx/forum.aspx?webtag=amdiabetesz&nav=index

ADA's Diabetes Learning Center
http://diabetes.org/about-diabetes.jsp
Joslin Center Beginner's Guide.
http://www.joslin.org/Beginners_guide.asp
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>I don't know what's going on, I'm shaking around the clock now.  Got
> almost no sleep last night because of bouts of the shakes plus night
[quoted text clipped - 21 lines]
>
> LQ
W.M.McKee - 05 Mar 2006 18:55 GMT
>I don't know what's going on, I'm shaking around the clock now.  Got
>almost no sleep last night because of bouts of the shakes plus night
[quoted text clipped - 3 lines]
>not correlating to the meter as much. I'm getting them when I first get
>up in the AM not even after eating.

Hi LQ,

I am so sorry to hear of your continuing distress. Seriously, it
sounds like you may be approaching the time for a trip to the ER. If
it is as bad as you seem to describe, something is goin on, and it is
not good....

Please take care, and keep us posted.

Will, T2
Michelle - 05 Mar 2006 19:50 GMT
LQ,

I agree with the others--this thing needs to be evaluated by a
competent medical professional.  Your description hits me as being a
combination of things--perhaps even something that hasn't been kicked
around here.  But that's just me thinking off the top of my head.

As for the 5HTP, it is very safe, albeit it is not recommended for use
with serotonin reuptake inhibitors or MAO inhibitors.  There was a
study (that unfortunately I cannot locate at the moment) which shows
that it performed as effectively as the SSRI's without as many
side-effects (the study was done in Europe, I believe).  I take it
occasionally.

Michelle
Loretta Eisenberg - 06 Mar 2006 00:02 GMT
LQ, I dont understand what is going on with you.  I dont read very low
numbers so I am wondering why you have the shakes.  

I hope you get to the doctor and get some answers.

Are you panicking over what is happening with your blood glucose.

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
Julie Bove - 06 Mar 2006 06:45 GMT
> I don't know what's going on, I'm shaking around the clock now.  Got
> almost no sleep last night because of bouts of the shakes plus night
[quoted text clipped - 19 lines]
>
> This is horrible, I can't continue like this.

It sounds like you have some sort of other medical problem aside from
diabetes.  Have you mentioned these symptoms to your Dr.?  162 is hardly
what I'd call a spike, especially at 1/2 an hour after eating.  I don't
think there are very many of us who test then.

 --
See my webpage:
http://mysite.verizon.net/juliebove/index.htm
Quentin Grady - 06 Mar 2006 09:01 GMT
This post not CC'd by email
On 5 Mar 2006 06:31:48 -0800, "LizardQueen" <GreenRaven@att.net>
wrote:

>The best I felt was Friday at work. It was busy there so ate a can of
>soup for lunch (all I had around) that had 40 g carbs in it (and fast
>ones at that).  I spiked at 162 at a half hour (could feel the heat and
>dizziness so I tested) then dropped 40 pts 10 minutes after that, went
>up a little at the 2 hour (127), then dropped again, but then my bg was
>ok the rest of the afternoon and my anxiety went away.

G'day G'day LQ,

 Reactive hypoglycemia might be one of the things going on.  Reactive
hypoglycemia is one of scariest things going. Sometimes there are few
symptoms that are recognizable to others.  All they might notice at
first is some flaccidness of the complexion.  My point is that
sometimes there is little that portrays the inner turmoil and
distress.

Some of the regulars might recall that when I was diagnosed with
reactive hypoglycemia it happened when a replacement locum sent me to
a specialist who ordered twelve blood tests. I actually had to ask if
it included the glucose tolerance test.  He said most people didn't
volunteer for that test because it could be stressful for some people.
Never the less he added the glucose tolerance test. The only test that
showed an abnormality was the extra test I had asked for.  

Now, there are a couple of lessons for all of us in this situation.

The first and most important is that symptoms can be very deceptive as
a basis for diagnosis.  The doctor was a respected specialist.  He
recognised the possibility of at least a dozen different causes that
fitted the presenting symptoms.  He followed the standard medical
procedure of elimination ie checking for a selection of possible
abnormalities and then crossing off the ones that turned out to be
normal.  

The second lesson is more subtle.  If I hadn't asked for the glucose
tolerance test then the probable diagnosis would have been that the
illness was not physiological and it would have been labeled as
psychosomatic and I would most likely have been treated
inappropriately.  

What I guess I am suggesting is to take good care to avoid a short
circuit diagnosis ... get a referral to a specialist if you can.  Find
the real cause.  A mistaken diagnosis will often lead to treatment
that makes things worse.

Best wishes,

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Michelle - 06 Mar 2006 21:17 GMT
Although Quentin didn't go so far as to recommend that you ask for a
glucose tolerance test, there is much wisdom in his personal
experience.  I was a lab tech, and it's the one test that will show
exactly how your body is reacting to glucose and how soon after
ingestion.  Ideally, the test should be done in conjunction with
insulin levels to get the fullest picture possible.  However, much can
be inferred about insulin levels from a person's reaction to the
glucose challenge.  I will warn you, though, (and I suspect this why
Quentin didn't go so far as to actually recommend the test) the test is
uncomfortable because it will bring on the symptoms you dread so much.
So from a scientific standpoint, the test is excellent; from a personal
standpoint that may not be true.  You have to make the call.

Michelle

P.S.  Have you considered thyroid problems?  I just did a review of
symptoms of hyperthyroidism, and some of what you describe fits.  I
know that you said that you needed to lose weight, so you probably
thought that would rule out being hyperthyroidism.  However, the
article I read said that someone who is hyperthyroid may be very skinny
OR the hyperthyroidism can increase appetite to the point that people
can gain lots of weight.  Something to consider?
Nicky - 06 Mar 2006 21:32 GMT
>  I was a lab tech

Michelle, could I ask your advice? I've been refused a fasting insulin test,
on the basis the lab doesn't do it. How complicated is that test? The lab is
a medium-sized hospital one. I'm fairly sure I'm being lied to...

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

Michelle - 06 Mar 2006 22:59 GMT
Hi Nicky,

I worked in a rural hospital, and although our lab didn't perform the
insulin test either, we sent it out to reference lab.  A reference lab
here in the States is a commercial lab that performs the more unusual
tests that smaller (or even medium sized) hospitals don't do because it
is cost prohibitive to keep the supplies and/or equipment on hand for
tests that are rarely requested.

As for the complication of it, although I've never performed the test,
it comes under the purview of a chemistry or radioimmunoassay analysis.
Depending on the technology, the test may require several steps (not
difficult) and reading by a machine, or may be as easy as plunking your
sample onto the machine and pressing "start".

Anyway, surely your local hospital uses a reference lab for more rare
tests?  That would be the question I'd ask.

Hope this helps!
Michelle
Nicky - 07 Mar 2006 12:36 GMT
> As for the complication of it, although I've never performed the test,
> it comes under the purview of a chemistry or radioimmunoassay analysis.
[quoted text clipped - 6 lines]
>
> Hope this helps!

Certainly does - thanks!

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

LizardQueen - 06 Mar 2006 21:34 GMT
I'm afraid of the GTT for that very reason - scared that I'll crash so
bad that I black out or get sick or whatever. Plus it will trash me for
the next 3 days, if the cinnamon heart episode is any indication (about
2 oz of cinnamon candy hearts on an empty stomach sent me from 109 ->
162 -> 111 in 45 minutes).

I'm also scared that if I blow a 200 on it for one early blood pull
(even if I'm well under that by the 2 hour mark) that it will be enough
to diag me as T2 which I don't want on my record for insurance reasons.

I have been wondering about thyroid, but all Dr. McQuacky (prior one)
did was run a TSH which came out fine (.89), not the full thyroid panel
that includes the T3 and T4.

I'm going to ask Doc 2.0 about this all on Wednesday.

I'm having a decent afternoon, after a shaky AM. Lunch was a chicken
and chickpea salad on lettuce. Tasted like crap :lol: but I had made it
in desperation and could easily calculate from the cans involved if it
had the 40/30/30 proportions that I would like to stick to. No wheat or
dairy in it either.
Ate it at 1:15, so far no crash, bg is dead level and I'm not hungry at
all, and I only ate a half cup of it.

Whereas this AMs eggs & flax bread breakfast had me shaking at 2 hours
and the cottage cheese snack only lasted a half hour.

Looks like it'll be the chickpea salad for breakfast :lol: - anyone
have a vomiting emoticon I can borrow?

LQ
Nicky - 07 Mar 2006 12:39 GMT
> Looks like it'll be the chickpea salad for breakfast :lol: - anyone
> have a vomiting emoticon I can borrow?

Ewwww : )   So what's so good about the chickpea salad, then - OK, it's got
the right ratios, but is there anything else about it? I'm thinking it's a
pretty good mix of fast and slow carbs, with plenty of protein. Fruit,
cheese and yoghurt on half a slice of rye might be similar, maybe?

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

tog - 06 Mar 2006 10:54 GMT
Dear LQ,

I hope when you visit the doctor he gives you a thorough examination and a
full blood test, including potassium levels etc.

Good luck for Wednesday,

sue

Signature

type2  A1c 5.6/5.8 Metformin1g

>I don't know what's going on, I'm shaking around the clock now.  Got
> almost no sleep last night because of bouts of the shakes plus night
[quoted text clipped - 21 lines]
>
> LQ
Sleepyman - 06 Mar 2006 22:48 GMT
>I don't know what's going on, I'm shaking around the clock now.  Got
>almost no sleep last night because of bouts of the shakes plus night
[quoted text clipped - 21 lines]
>
>LQ
I don't know kiddo, I am no doc, but it sounds like something
Neurological to me. JMO of course.

Sleepy

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