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Medical Forum / Diseases and Disorders / Diabetes / March 2006

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For Alan S

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Ozgirl - 02 Mar 2006 23:30 GMT
Is this of interest to you? Possibly you already know
anyway:

http://www.hypoglycemia.asn.au/articles/research_hypoglycemia.html

"AVOCADO EXTRACT: "The article suggests controlling blood
glucose sugar levels in order to "help starve the cancer and
bolster the immune system." It also suggests that
mannoheptulose, a purified avocado extract, may help.
Researchers at Britain's Oxford University Department of
Biochemistry found that mannoheptulose inhibits tumor cell
glucose uptake and also inhibits glucokinase, the enzyme
used in glycolysis. In laboratory tests, mannoheptulose
inhibited growth in cultured tumor cells as well as reducing
tumor size in animal subjects." Townsend Letter June 2002,
"Partial replacement of complex digestible carbohydrates
with monounsaturated fatty acids (avocado as one of its main
sources) in the diet of patients with non-insulin-dependent
diabetes mellitus improves the lipid profile favorably,
maintains an adequate glycemic control, and offers a good
management alternative." Lerman-Garber I, et als. 1994,"
Alan S - 03 Mar 2006 02:59 GMT
I changed the title, Jan. Read the final bit to see why.

>Is this of interest to you? Possibly you already know
>anyway:
[quoted text clipped - 17 lines]
>maintains an adequate glycemic control, and offers a good
>management alternative." Lerman-Garber I, et als. 1994,"

Hi Ozgirl

Thanks. Interesting. I eat an average of half an avocado a
day, in one form or another, and this just reinforces other
things I've read.

However, it got a little odd as I followed the links and
couldn't find the original paper, so the source is a little
suspect - I ended up here http://cat007.com/ - hardly a site
to fill you full of confidence.

So I did a little searching on Highwire and Scholar and
found the original abstract here:
http://care.diabetesjournals.org/cgi/content/abstract/17/4/311

The conclusions were as shown and I'll keep eating avocados
daily.

But something equally interesting developed. Below the
abstract is the list of "This article has been cited by
other articles:". The final citer is:

http://atvb.ahajournals.org/cgi/content/full/18/5/773
Differences in the Metabolism of Postprandial Lipoproteins
After a High-Monounsaturated-Fat Versus a High-Carbohydrate
Diet in Patients With Type 1 Diabetes Mellitus

And in their discussion this little gem is hidden:

"The present studies cannot exclude the possibility that
there are differences in the response to the two diets
between the two types of diabetes. Type 1 diabetes is
present in younger people and is not associated with
excessive insulin resistance, obesity, and dyslipidemia,
which are frequently seen in type 2 diabetes. Age, insulin
resistance, and dyslipidemia could affect the metabolic
response to a diet and could account for the differences
between our results and those reported in patients with type
2 diabetes. Our study raises the question whether the
dietary recommendations for the two types of diabetes may
need to be different."

They do recommend more studies  - but one wonders if the
ADA, Diabetes Australia or the NHS have come across this
one.

It is only 8 years old, after all.

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
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Everything in Moderation - Except Laughter.

Ozgirl - 03 Mar 2006 04:21 GMT
"Alan S" <loralweightandcarbs@optusnet.com.au> wrote in

> "The present studies cannot exclude the possibility that
> there are differences in the response to the two diets
[quoted text clipped - 12 lines]
> ADA, Diabetes Australia or the NHS have come across this
> one.

ADA was possibly one of the research funders (is that a
word?).
Jefferson - 03 Mar 2006 14:37 GMT
Hi Alan:

> But something equally interesting developed. Below the
> abstract is the list of "This article has been cited by
[quoted text clipped - 4 lines]
> After a High-Monounsaturated-Fat Versus a High-Carbohydrate
> Diet in Patients With Type 1 Diabetes Mellitus
(snipped)

> They do recommend more studies  - but one wonders if the
> ADA, Diabetes Australia or the NHS have come across this
> one.

Other studies have been done since then.

> It is only 8 years old, after all.

See the links at the end of the article for some subsequent articles.

Dietary cis-monounsaturated fatty acids and metabolic control in type 2
diabetes - http://www.ajcn.org/cgi/content/full/78/3/617S
(Note: The title to this one would perk Quentin's interest, but he has
probably read it already.) See table 1 for a list of foods containing a
high level of cis-monounsaturated fatty acids -
http://www.ajcn.org/cgi/content/full/78/3/617S/T1.

Dietary Fat as a Risk Factor for Type 2 Diabetes -
http://www.annalsnyas.org/cgi/content/abstract/967/1/324
(scholar.google.com: Dietary+Fat+as+a+Risk+Factor+for+Type+2+ Diabetes -
http://tinyurl.com/pzel2 and http://tinyurl.com/m3fcs - from find
articles: articles with similar topic.)

Frank
Alan S - 03 Mar 2006 21:05 GMT
<snip>

>> They do recommend more studies  - but one wonders if the
>> ADA, Diabetes Australia or the NHS have come across this
>> one.
>
>Other studies have been done since then.

<snip>

>Frank

Hi Frank, and Jan

I intended sarcasm, but failed to communicate:-)

I was implying that if they had read "The present studies
cannot exclude the possibility that there are differences in
the response to the two diets between the two types of
diabetes" then the bodies I mentioned were certainly taking
no notice of it.

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
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Everything in Moderation - Except Laughter.

 
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