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Medical Forum / Diseases and Disorders / Diabetes / March 2006

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Fasting Glucose & Cardiac Risk: Differs by Gender

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Jenny - 01 Mar 2006 13:10 GMT
Our ever-alert friends at http://www.diabetesincontrol.com discuss this
study this week:

http://aje.oxfordjournals.org/cgi/content/abstract/163/4/342

The short version:  Analysis of the Framingham Heart Study data comes up
with the information that for men, heart attack risk triples as FPG
rises from 70 to 100 mg/dl, then it flattens out.

For women, they found the risk is flat until FPG reaches 100 mg/dl, then
it rises steeply.

The authors conclude that 100 mg/dl is a good target for women, but not
men, but add that it isn't possible to know from this data whether
reducing FPG would reduce cardiac risk--a subject that would have to be
studied further.

From the abstract:
 "For men, adjusted mortality risk increased very rapidly through the
normal range (from 4.12% at 3.89 mmol/liter (70 mg/dl) to 12.26% at 5.55
mmol/liter (100 mg/dl)) and was flat at 12.26% thereafter. For women,
risk was flat at 3.65% through the normal range and then increased
rapidly, reaching 8.34% at 6.99 mmol/liter (126 mg/d), but increased
much more slowly thereafter."

--Jenny

http://www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
Loretta Eisenberg - 01 Mar 2006 14:14 GMT
Jenny, I would have thought that a blood glucose level of 100 would be a
fabulous number if maintained all the time, or is that only fbg.  I cant
comprehend too well.  What about the cholesterol /hdl ratio and the
homocystein levels. Do they factor into the risk .  mine was 2.7 which
is below the average and homocystein level was 6.91.  My fbgs range from
110 in the morning to 75 before lunch and about 90 before dinner.Do they
average these numbers or are they taken into account separately

Quentin are you there :-)

Loretta.

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
Jenny - 01 Mar 2006 18:53 GMT
> Jenny, I would have thought that a blood glucose level of 100 would be a
> fabulous number if maintained all the time, or is that only fbg.

While they didn't make it crystal clear in the summary of the article,
I'm almost certain it is only fasting blood glucose. The Framingham
study is one where a large group people were examined at set intervals
for many years--once a year, I think, so it wouldn't be likely they
would measure anything but the morning fasting glucose that is part of
the usual physical.

  What about the cholesterol /hdl ratio and the
> homocystein levels. Do they factor into the risk .  mine was 2.7 which
> is below the average and homocystein level was 6.91.

In this case, they said, if I recall correctly that they had factored
out the cholesterol, smoking, and other known risk factors when
analyzing the data, so the fasting blood sugar alone would be the issue
here.

--Jenny

http://www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
 
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