Medical Forum / Diseases and Disorders / Diabetes / March 2006
Type 2 Diabetes--The Cause??
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Peanutjake - 28 Feb 2006 23:07 GMT My sister-in-law is studying to be a Registered Nurse. She sent me the following question. I don't have the answer for her. Can you help?
PJ ---------------------------------------------------------------- What is the actual cause of type 2 Diabetes? I am looking for information on a scientific study that proves the cause. PLEASE GIVE ME THE NAME AND WEB ADDRESS OF THE SCIENTIFIC STUDY.
I am not looking for a description of the disease. I am not looking for someone's opinion. I am not looking for your opinion on what causes the disease. I am not looking for information about the prevention of the disease. I am not looking for information on the treatment of Diabetes. I am not looking for the cure.
I am looking for the actual cause. I would like the url of the scientific study that proves the cause.
Sarah - 28 Feb 2006 23:31 GMT > My sister-in-law is studying to be a Registered Nurse. > She sent me the following question. I don't have the answer for her. [quoted text clipped - 15 lines] > I am looking for the actual cause. > I would like the url of the scientific study that proves the cause. I am waiting with bated breath for the replies to this question.
If you insisted on an answer from me it would be "unknown". There are some statistically identified risk factors but no definitive answers. To compound the problem, Type 2 diabetes can take many different forms. Be prepared to take any answer with a grain of salt.
Sarah
wmmckee@cox.net - 28 Feb 2006 23:38 GMT > What is the actual cause of type 2 Diabetes? > > I am looking for information on a scientific study that proves the > > cause. Hi Sarah,
Maybe I am the ignorant one, but I don't think you are going to find anyone who will be able to identify a single definitive cause. Appears to arise from a group, or combination of factors, not the least of which is genetic predisposition.
I wish it were something so easy to address as BO, or clogged pores.....
Will, T2
Alan S - 28 Feb 2006 23:47 GMT >> My sister-in-law is studying to be a Registered Nurse. >> She sent me the following question. I don't have the answer for her. [quoted text clipped - 24 lines] > >Sarah The answer is simple. Nobody knows for sure. When they do, it will be a defining point in the development of a cure.
And, as other answers will note - first you have to agree on a definition of type 2 and it's multiple forms.
Cheers, Alan, T2, Australia. d&e, metformin 2x500mg
 Signature Everything in Moderation - Except Laughter.
Cheri - 01 Mar 2006 00:32 GMT :) -- Cheri
Sarah wrote in message ...
>> My sister-in-law is studying to be a Registered Nurse. >> She sent me the following question. I don't have the answer for her. [quoted text clipped - 24 lines] > >Sarah Ma¢k - 28 Feb 2006 23:33 GMT On 1 Mar 2006 00:07:25 +0100, "Peanutjake" <peanutjakeNO@SPAM.nonesuch.net> Huffed and Puffed the following into the madness of usenet:
>My sister-in-law is studying to be a Registered Nurse. >She sent me the following question. I don't have the answer for her. [quoted text clipped - 15 lines] >I am looking for the actual cause. >I would like the url of the scientific study that proves the cause. the single cause?
aint no such beast.
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"To announce that there must be no criticism of the President, or that we are to stand by the President right or wrong, is not only unpatriotic and servile, but is morally treasonable to the American public." ...Theodore Roosevelt
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Jesus never hated anyone.
Jennifer - 28 Feb 2006 23:48 GMT What is the actual case of cancers? Or of MS? Or of many diseases?
And if she's studying to be an RN, she should have access to research libraries where she can try to answer her own question.
Jennifer
> My sister-in-law is studying to be a Registered Nurse. > She sent me the following question. I don't have the answer for her. [quoted text clipped - 15 lines] > I am looking for the actual cause. > I would like the url of the scientific study that proves the cause. David - 28 Feb 2006 23:50 GMT > What is the actual case of cancers? Or of MS? Or of many diseases? > > And if she's studying to be an RN, she should have access to research > libraries where she can try to answer her own question. > > Jennifer for once we agree!
David - 28 Feb 2006 23:49 GMT > I am looking for the actual cause. > I would like the url of the scientific study that proves the cause. There is no "actual" cause, per se. BY THE TIME SHE BECOMES AN RN, SHE WILL HAVE ALREADY FOUND THAT OUT. let her do her studying. You don't need to interfere.
dave
Beav - 01 Mar 2006 00:15 GMT > My sister-in-law is studying to be a Registered Nurse. > She sent me the following question. I don't have the answer for her. [quoted text clipped - 3 lines] > ---------------------------------------------------------------- > What is the actual cause of type 2 Diabetes? IOf she has the answer to this, it's not a nurses job she should be entertaining, it's a full blown professorship of doctoring.
> I am looking for information on a scientific study that proves the cause. There isn't one, and this is beginning to look VERY troll like!
> PLEASE GIVE ME THE NAME AND WEB ADDRESS OF THE SCIENTIFIC STUDY. have you trid www.justfuckinggoogleit.com?
> I am not looking for a description of the disease. God.
> I am not looking for someone's opinion. What the f.ck ARE you looking for then?
> I am not looking for your opinion on what causes the disease. Well well, a man who knows what he doesn't want. Not often you fond one of those.
> I am not looking for information about the prevention of the disease. > I am not looking for information on the treatment of Diabetes. > I am not looking for the cure. > > I am looking for the actual cause. Good "look" finding it. I know, ask Andrew Chung
> I would like the url of the scientific study that proves the cause. I'm sure you would. You want information, but you won't get it number 2. You won't get it
 Signature Beav OMF#19 VN 750 Zed Thou
mail is beavis dot original at ntlworld dot com (with the obvious changes)
Evelyn Ruut - 01 Mar 2006 00:17 GMT > My sister-in-law is studying to be a Registered Nurse. > She sent me the following question. I don't have the answer for her. [quoted text clipped - 15 lines] > I am looking for the actual cause. > I would like the url of the scientific study that proves the cause. Hi Jake,
Wouldn't it be nice if there were a nice simple cause with a simple definition? A link we could just click on and know all the mysteries about what causes this and other illnesses?
Unfortunately there are too many people in this world who imagine it is caused by being overweight. Those of us who have the disease know it isn't all that simple. People like to find something or someone to blame. Sometimes there isn't any one thing to blame.
All I know is that living with it isn't a lot of fun. Having no energy, feeling tired a lot of the time, having to watch what we eat so carefully and still not being able to be carefree and what we call "normal" again.
The only answers I have been able to come up with are that there is something genetic about it, something goes haywire in our body chemistry which is aggravated by being overweight, and that it can be controlled but not ever really cured.
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Best Regards,
Evelyn (to reply to me personally, remove 'sox')
Cheri - 01 Mar 2006 00:40 GMT ITA Evelyn. I know some have said it's the best thing that's ever happened to them, but I've never agreed with that. I've had lots of things happen to me that I've enjoyed a Hell of a lot more. Would I sooner have lung cancer or something equally ugly? No, I'd rather not have any of them. :-)
-- Cheri
Evelyn Ruut wrote in message <7K5Nf.27$nB6.11@news-wrt-01.rdc-nyc.rr.com>...
>All I know is that living with it isn't a lot of fun. Having no energy, >feeling tired a lot of the time, having to watch what we eat so carefully [quoted text clipped - 4 lines] >Evelyn >(to reply to me personally, remove 'sox') Jenny - 01 Mar 2006 00:37 GMT > My sister-in-law is studying to be a Registered Nurse. > She sent me the following question. I don't have the answer for her. [quoted text clipped - 5 lines] > I am looking for information on a scientific study that proves the cause. > PLEASE GIVE ME THE NAME AND WEB ADDRESS OF THE SCIENTIFIC STUDY. Here's the best journal article about the current understanding of some of the different causes of type 2 diabetes.
http://edrv.endojournals.org/cgi/content/full/19/4/491
But your question is simplistic. Type 2 diabetes is not a single disorder. There are dozens if not hundreds of studies that identify specific genetic flaws that cause Type 2 diabetes in different populations. They are all different.
In fact, it's almost better to think of Type 2 diabetes as a combination of symptoms--insulin resistance and abnormally high blood sugar--rather than a specific disease, because failures at many different points in the body--insulin receptors, insulin producing cells, insulin storing cells etc, all can cause it.
--Jenny
http://www.phlaunt.com/diabetes Diabetes Info
http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood Sugar Under Control
>^;^< Great-Granny Grayfur - 01 Mar 2006 01:57 GMT Plus the outside influence of the steroid dependent patient.
Billie in AR
: In fact, it's almost better to think of Type 2 diabetes as a combination : of symptoms--insulin resistance and abnormally high blood sugar--rather : than a specific disease, because failures at many different points in : the body--insulin receptors, insulin producing cells, insulin storing : cells etc, all can cause it. Anil - 08 Mar 2006 12:20 GMT Jenny,
>> http://edrv.endojournals.org/cgi/content/full/19/4/491 That is very good research on your part. Peanutjack if your sister-in-law was looking for pointers to good research Jenny made your job one heck of an easy assignment. So at least say thank you to her.
While we all have interest in knowing why-the-hell-this-happened-to-me-syndrome, my own interest lies in trying to I guide my kids (I have to two boys 20 and 18 yrs old, both are Ultimate Frisbee players and hence in great shape). So trying to get a grip on environmental factors and genetic disposition is a key to set the right guide lines. The last thing I want them to feel is "What the heck, sooner or later I am going to get it any way so might as well have my sugar load now".
Thanks again Jenny for that pointer.
Anil
Yolande Smith - 08 Mar 2006 13:33 GMT > Jenny, > [quoted text clipped - 4 lines] > job one heck of an easy assignment. So at least say thank you to her. > SNIP> Hi Peanutjack
My impression when studying diabetes with the Open University along with many nurses was that their opinion was pretty firmly fixed on type 2 being a self-inflicted disease caused by dietary ignorance and gluttony. If your sister-in-law is looking for confirmation of this, I suspect this is the wrong place to search.
 Signature Yolande Type 2
Pete - 09 Mar 2006 13:38 GMT >My impression when studying diabetes with the Open University along with >many nurses was that their opinion was pretty firmly fixed on type 2 being a >self-inflicted disease caused by dietary ignorance and gluttony. If your >sister-in-law is looking for confirmation of this, I suspect this is the >wrong place to search. Although "dietary ignorance and gluttony" are not believed to be the sole cause - just a couple of the many other 'additional' factors that influence eventual outcome, there can be little doubt that these 2 things do make matters worse.
There are many people with personal experience in here who will testify that loosing weight, adjusting diet have indeed helped them manage their condition. There are also those who are on the verge of becoming medicated and who delay that eventuality by the same means.
I personally believe that it all starts from a very young age - if you are genetically predisposed. the candle that burns twice as bright lasts half as long or in other words - abuse of the body will over time reduce its efficiency.
It would be interesting to see some honest and complete lifestyle comparrisons compared to daibetics [T2] and non-diabetics. But I suppose even then there will be too many variables to draw any conclusive answers.
JMO
Alan S - 09 Mar 2006 21:40 GMT >>My impression when studying diabetes with the Open University along with >>many nurses was that their opinion was pretty firmly fixed on type 2 being a [quoted text clipped - 25 lines] > >JMO I don't make any pretence of it. I was obese when I was diagnosed. And that was totally my own responsibility.
I was quite surprised when I arrived here and discovered the hostility by some to any mention that weight may be a factor. I agree that the genetic aspects are a probable component and that a proportion of new diabetics are slim - but let's face it, many of us would not be posting here if we had been a little more active away from the table and a lot less active while sitting at the table.
I don't really care whether diabetes assisted my weight gain or vice versa - I was the prime reason for being fat, and I'm now the prime reason for no longer being fat. No-one force-fed me.
Cheers, Alan, T2, Australia. d&e, metformin 2x500mg
 Signature Everything in Moderation - Except Laughter.
Just - 10 Mar 2006 00:17 GMT > I don't make any pretence of it. I was obese when I was > diagnosed. And that was totally my own responsibility. [quoted text clipped - 11 lines] > I'm now the prime reason for no longer being fat. No-one > force-fed me. Same with me. I have been overweight for more than half of my life - starting from age 8. I think I caused my obesity not diabetes.
Nicky - 10 Mar 2006 08:39 GMT > Same with me. I have been overweight for more than half of > my life - starting from age 8. I think I caused my obesity > not diabetes. Think about that again as the weight comes off with normal blood sugars.
I don't believe excess weight was a particularly contributory factor for my diabetes; I'm certain uncontrolled diabetes made it easier to put weight on and made it impossible to take it off.
Having a dicky thyroid didn't help either.
Nicky.
 Signature A1c 10.5/5.4/<6 T2 DX 05/2004 1g Metformin, 100ug Thyroxine 95/74/72Kg
Just - 10 Mar 2006 14:32 GMT >> Same with me. I have been overweight for more than half of >> my life - starting from age 8. I think I caused my obesity [quoted text clipped - 5 lines] > for my diabetes; I'm certain uncontrolled diabetes made it easier to > put weight on and made it impossible to take it off. You think I had uncontrolled T2 diabetes at age 8 & I was diagnosed a few decades later?
> Having a dicky thyroid didn't help either. > > Nicky. Nicky - 10 Mar 2006 16:38 GMT >>> Same with me. I have been overweight for more than half of >>> my life - starting from age 8. I think I caused my obesity [quoted text clipped - 8 lines] > You think I had uncontrolled T2 diabetes at age 8 & I was diagnosed > a few decades later? I failed one GTT, then passed the followup after a low-carb diet, at age 10. At age 11 my Mum was feeding me up because I was too skinny. Either I have an amazingly delayed LADA - that's responding to metformin - or my uncontrolled diabetes only became symptomatic several decades after it was first found.
Nicky.
 Signature A1c 10.5/5.4/<6 T2 DX 05/2004 1g Metformin, 100ug Thyroxine 95/74/72Kg
Just - 10 Mar 2006 16:48 GMT >>>> Same with me. I have been overweight for more than half of >>>> my life - starting from age 8. I think I caused my obesity [quoted text clipped - 14 lines] > metformin - or my uncontrolled diabetes only became symptomatic > several decades after it was first found. Maybe that's so in your case, but not mine. There is absolutely no way I have had diabetes at age 8.
My weight problem wasn't because of sugar levels. It's rather silly to say that all people overeat & don't exercise enough because of diabetes. I overate because I like to overeat. I am a greedy pig, glutton, whatever. Note that I say "am" & not "was". Even now with fully controlled T2, I would love to eat & overeat, and it takes every inch of my will power to not do it. My craving for food hasn't diminished through different levels of a1c's from 10.5 to 5.4. If someone cured my diabetes tommorow, then the day after tommorow, I would spend eating nothing but Tim's Jalapeno Potato Chips through the day. I hate this disease like no other, because it uses up every bloody inch of my willpower to eat less to control my sugars & also come down from a 31 BMI to a 25 BMI.
Alan S - 11 Mar 2006 04:23 GMT >>>>> Same with me. I have been overweight for more than half of >>>>> my life - starting from age 8. I think I caused my obesity [quoted text clipped - 27 lines] >to not do it. My craving for food hasn't diminished >through different levels of a1c's from 10.5 to 5.4. Congratulations!
>If someone cured my diabetes tommorow, then the >day after tommorow, I would spend eating nothing [quoted text clipped - 3 lines] >less to control my sugars & also come down >from a 31 BMI to a 25 BMI. And congratulations again! How long do you think that iron resolve will last? I hope, honestly, all your life.
Do you remember Crosby, Stills and Nash?
"if you can't be with the one you love it's alright Go ahead and love the one, love the one, love the one you're with"
It may not be an ode to fidelity, but I've used that logic with my body. I was comfortable in my old body, fat and all, I enjoyed my old lifestyle, but it's all gone forever now. So I have to love the body I have, and learn to love the lifestyle rules that let that body continue a while longer. Like seeing Mississippi mud-cake as poisonous.
Love the one you're with. It's amazing what you can learn to like once you realise that your life depends on it.
Even broccoli.
Cheers, Alan, T2, Australia. d&e, metformin 2x500mg
 Signature Everything in Moderation - Except Laughter.
Just - 11 Mar 2006 04:54 GMT >>>>>> Same with me. I have been overweight for more than half of >>>>>> my life - starting from age 8. I think I caused my obesity [quoted text clipped - 40 lines] > And congratulations again! How long do you think that iron > resolve will last? I hope, honestly, all your life. I hope so too. Because I have no other alternative I know of.
> Do you remember Crosby, Stills and Nash? > [quoted text clipped - 9 lines] > lifestyle rules that let that body continue a while longer. > Like seeing Mississippi mud-cake as poisonous. I never have had too much craving for the sweet stuff, so that's not a big problem for me. I have hardly eaten any cakes even when I was overweight & before I was dx'ed.
> Love the one you're with. It's amazing what you can learn to > like once you realise that your life depends on it. I haven't learnt to like my current diet, especially the quantities, even after 6 years. But I know that I have no other alternatives.
Trinkwasser - 19 Mar 2006 21:50 GMT >>>> Same with me. I have been overweight for more than half of >>>> my life - starting from age 8. I think I caused my obesity [quoted text clipped - 14 lines] >uncontrolled diabetes only became symptomatic several decades after it was >first found. I've been having a succession of revelations about my medical history.
I have basically been buggered by getting a psychiatric diagnosis young, it's a well-known phenomenon particularly for female patients that a psychiatric diagnosis can hinder diagnosis of other diseases.
Now one revelation is the link between BG and not pissing immediately but *nocturia*, the higher my BG the more I retain water and the more I piss it out later, the relationship is pretty linear, eg. 5+ and I can pretty much last the night, 8+ means at least one nocturnal pee, 10+ guarantees two or three journeys to the loo.
Why did I first get a psychiatric diagnosis? I thought I was around 5-6 but mother tells me I was around 7-8 when I restarted wetting the bed. I was diagnosed with "neurosis" and "anxiety". Now I suspect they'd have dipped my pee and might even have done a fasting glucose, neither of which would have showed anything untoward.
But thinking about it, it was always in the wee small hours (sic) that I wet, in fact sometimes I'd have got up, gone into my parents' bed, fallen asleep again after they got up, and wissed.
The "cure" was to avoid drinking in the evening, pee straight before going to bed and again immediately on waking, which has stood me in pretty good stead until a few years back when I again became unable to last the night but at least managed to wake up and pee in the correct order.
In view of what I've learned about the familial histiory of diabetes and the particular way mine works, I have to wonder if in fact this was the first diabetic symptom . . .
Beav - 12 Mar 2006 14:46 GMT >> Same with me. I have been overweight for more than half of >> my life - starting from age 8. I think I caused my obesity [quoted text clipped - 5 lines] > my diabetes; I'm certain uncontrolled diabetes made it easier to put > weight on and made it impossible to take it off. Uncontrolled diabetes usually results in a LOSS of weight, not a gain. A medicated (actually OVER medicated) diabetic will put weight on at every oportunity though.
> Having a dicky thyroid didn't help either. Well it wouldn't would it? :-)
 Signature Beav OMF#19 VN 750 Zed Thou
mail is beavis dot original at ntlworld dot com (with the obvious changes)
Just - 12 Mar 2006 16:36 GMT > Uncontrolled diabetes usually results in a LOSS of weight, not a > gain. When exactly does weight loss happen with diabetes in type 2's? I have heard proximal neuropathy is usually accompanied by weight loss - but proximal neuropathy usually happens with high but not out of control sugar levels.
> A medicated (actually OVER medicated) diabetic will put weight > on at every oportunity though. That's only true with Sulfonylureas, I thought. Metformin helps you lose around 10 lbs. Byetta is supposed to make you lose even more.
Nicky - 12 Mar 2006 17:28 GMT > Uncontrolled diabetes usually results in a LOSS of weight, not a gain. Nah, the OP's T2 - remember it's very rare for us to get ketoacidosis.
Nicky.
 Signature A1c 10.5/5.4/<6 T2 DX 05/2004 1g Metformin, 100ug Thyroxine 95/74/72Kg
Ma¢k - 14 Mar 2006 01:39 GMT On Sun, 12 Mar 2006 13:46:25 -0000, "Beav" <beavis.original@ntlwoxoorld.com> Huffed and Puffed the following into the madness of usenet:
>>> Same with me. I have been overweight for more than half of >>> my life - starting from age 8. I think I caused my obesity [quoted text clipped - 9 lines] >medicated (actually OVER medicated) diabetic will put weight on at every >oportunity though. that's not true with type 2 diabetes.
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"To announce that there must be no criticism of the President, or that we are to stand by the President right or wrong, is not only unpatriotic and servile, but is morally treasonable to the American public." ...Theodore Roosevelt
(o ô) --ooO-(_)-Ooo--------------------
"I don't know half of you half as well as I should like; and I like less than half of you half as well as you deserve." ....Bilbo Baggins
Jesus never hated anyone.
Yolande Smith - 10 Mar 2006 13:37 GMT >>>My impression when studying diabetes with the Open University along with >>>many nurses was that their opinion was pretty firmly fixed on type 2 [quoted text clipped - 45 lines] > Cheers, Alan, T2, Australia. > d&e, metformin 2x500mg I am a little saddened by the misunderstanding of my posting. Of course any additional weight can be a problem and I accept that - although I do not accept gluttony in my case. I followed very closely the "balanced diet regime" advocated by the "experts" but still put on weight after the age of 65 and was diagnosed with type 2 at the age of 70. I have only been able to lose some weight since diagnosis and reduction of carbs.
But the attitude of NHS nurses which I encountered was that - all type 2's had to do was to eat less and follow the "balanced diet regime" and there would not have been a problem. Testing was for fanatics and most type 2's were too thick or lazy to alter their lifestyle. I don't think this is the ethos of this group. If it is, then I am in the wrong place.
 Signature Yolande Type 2
Ma¢k - 10 Mar 2006 14:51 GMT On Fri, 10 Mar 2006 13:37:03 GMT, "Yolande Smith" <Yolande@ntlworld.com> Huffed and Puffed the following into the madness of usenet:
>>>>My impression when studying diabetes with the Open University along with >>>>many nurses was that their opinion was pretty firmly fixed on type 2 [quoted text clipped - 58 lines] >were too thick or lazy to alter their lifestyle. I don't think this is the >ethos of this group. If it is, then I am in the wrong place. the NHS nurses were wrong, but that is not surprising. It sounds like you were a typical type 2 diabetic. You developed insulin resistance and as a result started gaining weight, and as a result of that the insulin resistance increased and again so did the weight gain. Until diagnosis and a change in diet and or the addition in meds. Allowing you to reduce BG and reduce insulin resistance and then start to lose the weight.
What they describe as a "balanced diet regime" is probably far too high in carbs for a type 2 diabetic and may even be questionable for a non-diabetic at your age.
by the way you are cross posting to 2 separate diabetes groups. ASD (alt.support.diabetes) and ASDUK (alt.support.diabetes.uk) there are some differences between the groups but as far as I know neither supports the idea of blaming the individual for something that is beyond their control. Hint if weight were the cause of type 2 diabetes, every over weight person on the planet would be type 2. That is simply not the case. Genetics still plays a deciding role in who becomes and does not become a diabetic. Weight is only a contributing factor and symptom, not "the" cause. Anyone in the medical profession who believes that weight is "the" cause as your NHS nurses appear to should get another job say in something like waste disposable, at least then they would feel comfortable working with the materials they normally live with in their heads.
 Signature Mâck©® Deltec CoZmore Pumper Type 1 since 1975 http://www.alt-support-diabetes.org http://www.diabetic-talk.org http://www.insulin-pumpers.org
"To announce that there must be no criticism of the President, or that we are to stand by the President right or wrong, is not only unpatriotic and servile, but is morally treasonable to the American public." ...Theodore Roosevelt
(o ô) --ooO-(_)-Ooo--------------------
"I don't know half of you half as well as I should like; and I like less than half of you half as well as you deserve." ....Bilbo Baggins
Jesus never hated anyone.
Pete - 10 Mar 2006 15:57 GMT >>>>My impression when studying diabetes with the Open University along with >>>>many nurses was that their opinion was pretty firmly fixed on type 2 >>>>being a >>>>self-inflicted disease caused by dietary ignorance and gluttony. If your >>>>sister-in-law is looking for confirmation of this, I suspect this is the >>>>wrong place to search.
>>>Although "dietary ignorance and gluttony" are not believed >>>to be the sole cause - just a couple of the many other >>>'additional' factors that influence eventual outcome, there >>>can be little doubt that these 2 things do make matters >>>worse.
>>>There are many people with personal experience in here who >>>will testify that loosing weight, adjusting diet have indeed >>>helped them manage their condition. There are also those who >>>are on the verge of becoming medicated and who delay that >>>eventuality by the same means.
>>>I personally believe that it all starts from a very young >>>age - if you are genetically predisposed. the candle that >>>burns twice as bright lasts half as long or in other words - >>>abuse of the body will over time reduce its efficiency.
>>>It would be interesting to see some honest and complete >>>lifestyle comparrisons compared to daibetics [T2] and >>>non-diabetics. But I suppose even then there will be too >>>many variables to draw any conclusive answers. >>>JMO
>> I don't make any pretence of it. I was obese when I was >> diagnosed. And that was totally my own responsibility.
>> I was quite surprised when I arrived here and discovered the >> hostility by some to any mention that weight may be a [quoted text clipped - 3 lines] >> we had been a little more active away from the table and a >> lot less active while sitting at the table.
>> I don't really care whether diabetes assisted my weight gain >> or vice versa - I was the prime reason for being fat, and >> I'm now the prime reason for no longer being fat. No-one >> force-fed me. >> Cheers, Alan, T2, Australia. >> d&e, metformin 2x500mg
>I am a little saddened by the misunderstanding of my posting. Of course any >additional weight can be a problem and I accept that - although I do not >accept gluttony in my case. I followed very closely the "balanced diet >regime" advocated by the "experts" but still put on weight after the age of >65 and was diagnosed with type 2 at the age of 70. I have only been able to >lose some weight since diagnosis and reduction of carbs.
>But the attitude of NHS nurses which I encountered was that - all type 2's >had to do was to eat less and follow the "balanced diet regime" and there >would not have been a problem. Hence my [and others] lack of enthusiasm for most of that ilk. However their fault is in not furthering their education but just accepting what has been spoon fed to them.
> Testing was for fanatics I s'pose many would have viewed my activities in the early days as being fanatical. But as they say 'the proof of the pudding is in the toilet'. [It worked for me simply as a device for enlightenment]
> and most type 2's were too thick or lazy to alter their lifestyle. The sad fact is that this is the case. Well so far as I have experienced in my locality.
> I don't think this is the ethos of this group. If it is, then I am > in the wrong place. no it is definately not.
Alan S - 11 Mar 2006 04:30 GMT >>>>My impression when studying diabetes with the Open University along with >>>>many nurses was that their opinion was pretty firmly fixed on type 2 [quoted text clipped - 58 lines] >were too thick or lazy to alter their lifestyle. I don't think this is the >ethos of this group. If it is, then I am in the wrong place. I'm becoming confused - but that happens easily - I think you may have misunderstood my comment on Pete's comment. By the time a thread goes through a few posts the original emphasis can change.
However, I certainly agree with your final comments.
Cheers, Alan, T2, Australia. d&e, metformin 2x500mg
 Signature Everything in Moderation - Except Laughter.
Russ - 11 Mar 2006 05:22 GMT Hi Yolande. The NHS nurses you describe are simply ignorant. There is a spectrum of insulin resistance which runs from the fairly innocuous Syndrome X on the far left, through [dys]metabolic syndrome and on to type 2 diabetes at the far right side of the spectrum. Insulin resistance starves our muscles and liver of glucose, so people who are insulin resistant feel bad much of the time. The more insulin resistant they are, the worse they feel. Most insulin resistant people soon learn that they can chase those bad feelings away by eating, and especially by eating carbohydrates. If you are both rich and insulin resistant, you can spend time at health resorts, hire personal nutritionists, and probably cope with your insulin resistance pretty well. If you are an ordinary person with a job to go to, or children to take care of, you will often feel like you just can't cope for another five minutes without a soda, a candy bar, a banana, etc. The extra carbohydrates raise your blood sugar so high that a little extra glucose gets into your liver and muscles and you feel capable of dealing with life again for a short while. When an insulin resistant person forces her glucose high enough to cope with life for another hour or two, some of that extra glucose is converted to fat. Insulin resistant people tend to burn more fat and less glucose, but they never burn as much fat as they gain. Cruelly, it turns out that burning more fat year after year poisons our liver and muscle cells with oxidized fat. The oxidized fat then makes us more insulin resistant. This starts a vicious cycle that very few people are able to break out of. Gluttony and will power are not issues in this process. If insulin resistant people live long enough, they will be come type 2 diabetics--most, however, die of something else first. Russ Farris http://www.potbellysyndrome.com =======================
> I am a little saddened by the misunderstanding of my posting. Of course any > additional weight can be a problem and I accept that - although I do not [quoted text clipped - 8 lines] > were too thick or lazy to alter their lifestyle. I don't think this is the > ethos of this group. If it is, then I am in the wrong place. Trinkwasser - 19 Mar 2006 21:39 GMT >> My sister-in-law is studying to be a Registered Nurse. >> She sent me the following question. I don't have the answer for her. [quoted text clipped - 21 lines] >the body--insulin receptors, insulin producing cells, insulin storing >cells etc, all can cause it. Hey thanks, that's an excellent paper.
If nothing else it proves I'm not as stupid as I look, I'd come to much the same conclusions as you, now I know why.
Beav - 01 Mar 2006 00:46 GMT > My sister-in-law is studying to be a Registered Nurse. > She sent me the following question. I don't have the answer for her. > Can you help? Are you going to post this EVERYWHERE?
 Signature Beav OMF#19 VN 750 Zed Thou
mail is beavis dot original at ntlworld dot com (with the obvious changes)
Paul - 03 Mar 2006 18:01 GMT >> My sister-in-law is studying to be a Registered Nurse. >> She sent me the following question. I don't have the answer for her. >> Can you help? > >Are you going to post this EVERYWHERE? He hasn't posted it to uk.rec.cycling.
And we're all feeling a little hurt.
Beav - 06 Mar 2006 20:34 GMT > On Wed, 1 Mar 2006 00:46:06 -0000, "Beav" > <beavis.original@ntlwoxoorld.com> [quoted text clipped - 9 lines] > > And we're all feeling a little hurt. Give us the addy, I'll send it ;-))
 Signature Beav OMF#19 VN 750 Zed Thou
mail is beavis dot original at ntlworld dot com (with the obvious changes)
Sleepyman - 01 Mar 2006 00:59 GMT >My sister-in-law is studying to be a Registered Nurse. >She sent me the following question. I don't have the answer for her. [quoted text clipped - 15 lines] >I am looking for the actual cause. >I would like the url of the scientific study that proves the cause. The wrong parents.
Sleepy
------------------------------------------------------------------ It is easier to make a saint out of a libertine than out of a prig. -George Santayana (1863-1952) ------------------------------------------------------------------
Susan - 01 Mar 2006 01:02 GMT > My sister-in-law is studying to be a Registered Nurse. > She sent me the following question. I don't have the answer for her. [quoted text clipped - 15 lines] > I am looking for the actual cause. > I would like the url of the scientific study that proves the cause. At the risk of sounding schoolmarmish, she could really put a tad more personal effort and thought into the subject.
Susan
Stratman - 01 Mar 2006 09:46 GMT | x-no-archive: yes | [quoted text clipped - 22 lines] | | Susan Or put "nurse" and "sister" into a search engine ;-)
MaryL - 01 Mar 2006 01:16 GMT > My sister-in-law is studying to be a Registered Nurse. > She sent me the following question. I don't have the answer for her. [quoted text clipped - 15 lines] > I am looking for the actual cause. > I would like the url of the scientific study that proves the cause. This is only my opinion (despite the clear statement in the question), but I believe your sister is asking the impossible. There are risk factors associated with T2, but I do not believe a specific "cause" has been identified -- and may not exist. Here is an article (definitely *not* a scientific study) that you sister may want to read: http://diabetes.about.com/od/type2diabetes/a/type2causes.htm
MaryL
rleone@hotmail.com - 01 Mar 2006 12:31 GMT Dear Peanutjake: Hiya! Last time I checked (American Diabetes Association 65th annual scientific session, June 2005) the best I could come up with as to the actual, unitary cause of type 2 DM is that, down in the deep biochemical heart of the matter, where the homocystine meets the mitochondria, the minds of the day are still playing "My hormone is better than your hormone." And it's getting really rough on the poor rats. If you REALLY want, contact me backchannel and i'll postally mail you a spare CD of the abstract book IF I can find one.
Robert Leone rleone@hotmail.com
SNIP> What is the actual cause of type 2 Diabetes?
> I am looking for information on a scientific study that proves the cause. > PLEASE GIVE ME THE NAME AND WEB ADDRESS OF THE SCIENTIFIC STUDY. SNIP
Zozzer - 01 Mar 2006 22:35 GMT Your joking.
Since WHEN did the medical staff demand the patience provide scientific evidence of causation of a condition. or disease.
I'm totally shocked at this LAZY attitude.
Learn to study, or choose another carear.
-- Zozzer
Peanutjake - 01 Mar 2006 23:36 GMT Thanks to everyone who answered the question in an intelligent and thoughtful manner.
The answer does seem to be that we do not yet know the actual cause or method of prevention for type 2 Diabetes.
Hopefully it will not be long before we do have a better answer.
PJ
Chris Malcolm - 02 Mar 2006 09:20 GMT In alt.support.diabetes Peanutjake <peanutjakeNO@spam.nonesuch.net> wrote:
> Thanks to everyone who answered the question in an intelligent and > thoughtful manner.
> The answer does seem to be that we do not yet know the actual cause or > method of prevention for type 2 Diabetes.
> Hopefully it will not be long before we do have a better answer. I doubt it, since the problem is in the question.
 Signature Chris Malcolm cam@infirmatics.ed.ac.uk +44 (0)131 651 3445 DoD #205 IPAB, Informatics, JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK [http://www.dai.ed.ac.uk/homes/cam/]
Beav - 03 Mar 2006 17:50 GMT > Thanks to everyone who answered the question in an intelligent and > thoughtful manner. [quoted text clipped - 3 lines] > > Hopefully it will not be long before we do have a better answer. I'm holding out for at least another 100 years. Any advance?
 Signature Beav OMF#19 VN 750 Zed Thou
mail is beavis dot original at ntlworld dot com (with the obvious changes)
Peter C - 04 Mar 2006 21:15 GMT > Thanks to everyone who answered the question in an intelligent and > thoughtful manner. [quoted text clipped - 3 lines] > > Hopefully it will not be long before we do have a better answer. There is a good chance the answers on the causes of Type 2 are already hidden in all the research that is going on ; it might just need another Pasteur to come along and put the pieces of the jigsaw puzzle together in a new way.
Chris Malcolm - 05 Mar 2006 13:21 GMT In alt.support.diabetes Peter C <peterc_2003@europe.com> wrote:
>> Thanks to everyone who answered the question in an intelligent and >> thoughtful manner. [quoted text clipped - 3 lines] >> >> Hopefully it will not be long before we do have a better answer.
> There is a good chance the answers on the causes of Type 2 > are already hidden in all the research that is going on ; > it might just need another Pasteur to come along and > put the pieces of the jigsaw puzzle together in a new way. If the history of science is any guide, when this Pasteur comes along with his new fangled ideas he may well at first be derided and mocked for years, possibly decades, by his fellow scientists. He might even now be struggling to find a peer-reviewed journal which will publish his work :-)
 Signature Chris Malcolm cam@infirmatics.ed.ac.uk +44 (0)131 651 3445 DoD #205 IPAB, Informatics, JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK [http://www.dai.ed.ac.uk/homes/cam/]
Bernard Peek - 05 Mar 2006 13:58 GMT >If the history of science is any guide, when this Pasteur comes along >with his new fangled ideas he may well at first be derided and mocked >for years, possibly decades, by his fellow scientists. He might even >now be struggling to find a peer-reviewed journal which will publish >his work :-) Only if you get your "history of science" from reading the News of the World. Most scientific advances are made by lots of people working on parts of a problem and eventually reaching a consensus. There are always lots of crackpot theories around and 99.999% of them are completely bogus. It's only the ones that are eventually proved right that get reported in the papers. So the tales of the plucky lone genius battling the establishment are newsworthy only because they are rare. If they happened more often you wouldn't hear about them unless you read the relevant journals. Which journals do you usually read?
 Signature Bernard Peek
W. Baker - 05 Mar 2006 17:37 GMT : >If the history of science is any guide, when this Pasteur comes along : >with his new fangled ideas he may well at first be derided and mocked : >for years, possibly decades, by his fellow scientists. He might even : >now be struggling to find a peer-reviewed journal which will publish : >his work :-)
: Only if you get your "history of science" from reading the News of the : World. Most scientific advances are made by lots of people working on [quoted text clipped - 5 lines] : happened more often you wouldn't hear about them unless you read the : relevant journals. Which journals do you usually read? What about H Pylori and ulcers? How long wsa the person who worked on that theory ostracised before anyone would listen? In science, as in most fields, if you go against the common wisdom you can easily have a very hard time.
Wendy
Bernard Peek - 05 Mar 2006 19:41 GMT >What about H Pylori and ulcers? How long wsa the person who worked on >that theory ostracised before anyone would listen? As far as I recall his theory took several years to be accepted, but nobody was ever ostracised. It's the way science works. Someone puts up a theory and everyone else tries to shoot it down. If they fail it gets accepted as probably true. With Helicobacter and ulcers the system worked perfectly. If you want to criticise the system find failures not successes.
> In science, as in most >fields, if you go against the common wisdom you can easily have a very >hard time. Well, yes. The system has been carefully designed over several hundred years to do just that.
 Signature Bernard Peek
Chris Malcolm - 05 Mar 2006 19:00 GMT In alt.support.diabetes Bernard Peek <bap@shrdlu.com> wrote:
>>If the history of science is any guide, when this Pasteur comes along >>with his new fangled ideas he may well at first be derided and mocked >>for years, possibly decades, by his fellow scientists. He might even >>now be struggling to find a peer-reviewed journal which will publish >>his work :-)
> Only if you get your "history of science" from reading the News of the > World. Most scientific advances are made by lots of people working on [quoted text clipped - 5 lines] > happened more often you wouldn't hear about them unless you read the > relevant journals. Which journals do you usually read? I regularly read New Scientist. I regularly dip into Scientific American, Nature, the British Medical Journal, and Behavioural and Brain Sciences. I keep an eye on the contents lists of the New England Journal of Medicine and the Journal of the American Medical Association. I read individual papers from a wide variety of journals and conference proceedings, covering the areas of philosophy of mind, cognitive science, artificial intelligence, computer science, medicine, psychiatry, ethology, evolution, anthrolopogy, and philosophy and history of science.
Before I retired I used to teach an introductory postgrad class in philosophy and history of science. Over the decades I accumulated copious teaching papers and notes some of which are likely to form the basis of a book.
In my own field of research I watched a novel revolutionary theory grow from an unpublishable idea communicated by photocopies between the revolutionaries to an accepted pardigm with its own journals and conferences, and in my own small way contributed to it.
How about you? From your comments I don't think there's much history of science on your own personal bookshelves, and I don't think you've read any of Kuhn's stuff on scientific revolutions.
I mention Kuhn because I think the sciences surrounding diabetes and nutrition are in the phase of growing controversy and unexpected and contradictory research results which presage a scientific revolution. It is that which I consider to be at the root of the controversy in this newsgroup between what me might call the orthodox and the exploratory.
 Signature Chris Malcolm cam@infirmatics.ed.ac.uk +44 (0)131 651 3445 DoD #205 IPAB, Informatics, JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK [http://www.dai.ed.ac.uk/homes/cam/]
Bernard Peek - 05 Mar 2006 20:38 GMT >In alt.support.diabetes Bernard Peek <bap@shrdlu.com> wrote: > [quoted text clipped - 28 lines] >copious teaching papers and notes some of which are likely to form the >basis of a book. You would be mistaken in thinking that there's not much history of science material on my bookshelves, there has been some since I became a scientist after reading a biography of Faraday at about the age of eight. I've done applied research in biochemistry, electronic engineering, metrology and my guess is that I'll end up doing research in management theory.
There are certainly theories that took years perhaps even centuries to be accepted. Evolution is still not universally accepted. But most theories get proposed, debated and either accepted or rejected without the man in the street either knowing or caring very much.
But the theories that do affect the man in the street are probably going to be harder to prove; extraordinary claims require extraordinary proof. That's how the scientific system has worked, mostly successfully, since at least the inception of the Royal Society. Pasteur's theories were mocked for years. But that isn't a failing of the scientific method or its practise, it is an example of its success. Proposed theories are roundly criticised and if they succeed they get accepted.
With 20:20 hindsight it's easy to point to some theories that took a long time to be accepted. But those theories are self-selecting. For you to quote them they need to meet several criteria. They have to have been accepted as true, they have to have had active opposition, and they have to have been publicised well enough to appear in the books on the history of science, they have to have entered the popular consciousness so that they resonate with the people who hear your comments. All of that makes them more visible than all of the other theories that were accepted with little or no comment and perhaps only token opposition.
So yes, Pasteur did face a lot of opposition, and a tabloid journalist would build a great human-interest story about that, while ignoring every other story that couldn't be used to support his point. It's true that Pasteur's theory was derided for years. It's true, but I think it is misleading to quote it selectively as an example.
[...]
>I mention Kuhn because I think the sciences surrounding diabetes and >nutrition are in the phase of growing controversy and unexpected and >contradictory research results which presage a scientific revolution. >It is that which I consider to be at the root of the controversy in >this newsgroup between what me might call the orthodox and the >exploratory. Contradictory evidence usually does presage some form of revolutionary change, which is quite predictable. I think it always presages a revolutionary change or a revelation of scientific fraud.
There is a significant amount of research that has produced repeatable results. But the fact that they appear contradictory is an artefact of the state of our knowledge. We do not have a Theory of Everything that explains all of the observations. The absence of such a theory is a prerequisite for the evidence to be classified as contradictory.
If all of the evidence was seen as consistent it would have been because there was already a theory that predicted it. So yes there may be a scientific revolution in the offing, but it is a predictable and routine revolution. Predicting it, if all of the evidence is genuine, is trivially easy.
 Signature Bernard Peek London, UK. DBA, Manager, Trainer & Author.
Chris Malcolm - 07 Mar 2006 02:06 GMT In alt.support.diabetes Bernard Peek <bap@shrdlu.com> wrote:
>>In alt.support.diabetes Bernard Peek <bap@shrdlu.com> wrote: >> [quoted text clipped - 28 lines] >>copious teaching papers and notes some of which are likely to form the >>basis of a book.
> You would be mistaken in thinking that there's not much history of > science material on my bookshelves, there has been some since I became a > scientist after reading a biography of Faraday at about the age of > eight. I've done applied research in biochemistry, electronic > engineering, metrology and my guess is that I'll end up doing research > in management theory. Applied research is a completely different kind of problem solving. Most importantly with respect to this discussion, there is nothing in applied research corresponding to the revolutionary changes which periodically and inevitably occur in pure research.
> There are certainly theories that took years perhaps even centuries to > be accepted. Evolution is still not universally accepted. There is as universal a consensus as you'll ever get amongst those working in the field. The people who so vocally don't accept it are those who will not accept contradictions of their religious dogma.
> But most > theories get proposed, debated and either accepted or rejected without > the man in the street either knowing or caring very much. The point is what kind of debate settled the issue amongst the scientists. Juries of the people do not decide scientific truth.
> But the theories that do affect the man in the street are probably going > to be harder to prove; extraordinary claims require extraordinary proof. Most of the theories which affect the man in the street do so without his knowledge. He uses technologies every day whose development depended on critical changes in thinking of which he knows nothing. I can't see any reason why the theories which affect the man in the street should be any more extraordinary than those which don't, unless by "extraordinary" you mean those theories which the man in the street thinks are extraordinary. However, since the man in the street does not play a part in the acceptance of scientific theories by the scientific community, I don't see what his judgments of extraordinariness have to do with anything.
> That's how the scientific system has worked, mostly successfully, since > at least the inception of the Royal Society. Pasteur's theories were > mocked for years. But that isn't a failing of the scientific method or > its practise, it is an example of its success. Proposed theories are > roundly criticised and if they succeed they get accepted. My remarks about a modern day Pasteur struggling to get his theories published wasn't a criticism of the way the scientific method worked, it was a description. The scientific method is a social invention whose processes tend in the long term towards the development of ever more accurate models of the way things work, despite the errors, biasses, and even cheating, of individual fallible human scientists.
It is not unusual for the dispute between a new and old theory to lack the ideal critical decisive experiment beloved of theorists. Sometimes there is much to be said for both sides, just a certain advantage of elegance and promise of future frutifulness in the new. In the minds of older scientists, that minor advantage is often outweighed by the advantages of the familiar and their expertise in it. In these cases we may have to wait for the older conservative scientists to die before a general consensus in favour of the new is possible. That sometimes seems to be the reason for the decades which sometimes elapse between the time the evidence and arguments for a new theory are all in place, and when it it is accepted by the general consensus of the most authoritative scientists.
> With 20:20 hindsight it's easy to point to some theories that took a > long time to be accepted. But those theories are self-selecting. For you > to quote them they need to meet several criteria. They have to have been > accepted as true, they have to have had active opposition, and they have > to have been publicised well enough to appear in the books on the > history of science, That was true in the early days of the philosophy of science. Historians of science now try to avoid that by going back to the original source materials, such as the notebooks and correspondence of the scientists concerned.
> they have to have entered the popular consciousness > so that they resonate with the people who hear your comments. That would only be the case if truth depended on being accepted by the people. I think we're fortunate that it doesn't.
> All of > that makes them more visible than all of the other theories that were > accepted with little or no comment and perhaps only token opposition. You seem to be mounting a statistical argument which argues that although difficult scientific revolutions occur, they mostly don't, so those difficult ones don't matter so much. It's not a question of chance, a lottery of public fashion and opinons which decides whether or not a new idea fits in without controversy or requires a revolutionary change of thinking. It's a very important fundamental difference in the nature of the concepts. It's in the nature of scientific progress that unocontroverial piecewise improvement can't go on for ever. Its basic ideas and methods have a natural maximum scope, and sooner or later it reaches a ceiling where no further progress is possible. It's like a climber who has reached the summit of a small mountain among bigger ones. The only way to go higher is first of all to abandon that summit and go down again.
> So yes, Pasteur did face a lot of opposition, and a tabloid journalist > would build a great human-interest story about that, while ignoring > every other story that couldn't be used to support his point. It's true > that Pasteur's theory was derided for years. It's true, but I think it > is misleading to quote it selectively as an example. You are right that it is most misleadingly uncharacteristic of the uncontroversial piecewise progress which most of the history of science has been spent in. Kuhn called that normal science. The point you're missing is that these infrequent cataclysmic scientific revolutions are not aberrations, they are completely fundamental to the progress of science, and are guaranteed to turn up in the progress of any science.
>>I mention Kuhn because I think the sciences surrounding diabetes and >>nutrition are in the phase of growing controversy and unexpected and >>contradictory research results which presage a scientific revolution. >>It is that which I consider to be at the root of the controversy in >>this newsgroup between what me might call the orthodox and the >>exploratory.
> Contradictory evidence usually does presage some form of revolutionary > change, which is quite predictable. I think it always presages a > revolutionary change or a revelation of scientific fraud. Exactly.
> There is a significant amount of research that has produced repeatable > results. But the fact that they appear contradictory is an artefact of > the state of our knowledge. We do not have a Theory of Everything that > explains all of the observations. The absence of such a theory is a > prerequisite for the evidence to be classified as contradictory. Exactly.
> If all of the evidence was seen as consistent it would have been because > there was already a theory that predicted it. So yes there may be a > scientific revolution in the offing, but it is a predictable and routine > revolution. Predicting it, if all of the evidence is genuine, is > trivially easy. If it's trivially easy to predict these routine revolutions, how come so many intelligent scientists are on record as having very strongly and persistently resisted this trivially easy conclusion?
Perhaps the clue is to be found in your remark "if all the evidence is genuine". There is a an enormous can of worms there, both theoretically, and in terms of the historical record. I can't offhand think of any revolution in which anyone could possibly have known if all of the evidence was genuine. One of the difficult problems is that it is very hard to say what the results of any experiment are without making prior theoretical assumptions, and if those theoretical assumptions are being questioned, then so are the results.
Indeed it has sometimes happened that a long accepted uncontroversial experiment whose results supported the existing theories, can many decades later, in the light of the new theory now accepted, be re-interpreted as contradicting the old theory and showing the superiority of the new. Same experiment, same data, same numbers, but radically different results depending on theoretical context.
All of this discussion arose in the context of the suggestion that the theories underlying diabetes might be in this critical pre-revolutionary state. That's a very important point, because whether or not it's true changes the whole attitude with which we should view current experiments and controversies in the treatment of diabetes.
 Signature Chris Malcolm cam@infirmatics.ed.ac.uk +44 (0)131 651 3445 DoD #205 IPAB, Informatics, JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK [http://www.dai.ed.ac.uk/homes/cam/]
Jenny - 06 Mar 2006 00:20 GMT Chris Malcolm wrote:.
> I mention Kuhn because I think the sciences surrounding diabetes and > nutrition are in the phase of growing controversy and unexpected and > contradictory research results which presage a scientific revolution. > It is that which I consider to be at the root of the controversy in > this newsgroup between what me might call the orthodox and the > exploratory. I wonder how the openness of the web will impact the process that Kuhn described so well.
Just today, for example, I saw an article in the mainstream media pointing to a bunch of studies that make it very clear that the high intake of sodas filled with high fructose corn syrup is a major reason for the so-called obesity epidemic because unlike sucrose high fructose corn syrup doesn't turn off hunger signals. The researchers quoted came from Harvard and a bunch of similar "name brand" institutions and made it sound like this once fringe idea had become mainstream doctrine. (The article also gave equal space to the apologists for the soda industry, which could be the subject of a whole nother thread).
But what struck me was that I'd read speculations about sodas containing high fructose corn syrup being linked to the obesity epidemic least 5 years ago online along with well-reasoned arguments comparing the incidence of obesity before and after sugar had been replaced with corn syrup (and the politics of why that happened.) Others also mentioned that in some parts of Europe sodas still were made with sugar and that obesity was not as prevalent there.
Does the web discussion of these topics somehow leak through? We all know that there are hundreds of readers for everyone who posts online.
In a similar manner, the diet advice that has helped us diabetics get control was being posted online 7 years ago, at a time when those of us who raised the topic were routinely accused of attempting to murder diabetics. But the important thing is that our experiences and our logic was available, and I think it might be possible that the public discussion has had an impact on people more plugged into the science mainstream.
What do you think? to any thinking person who was reading the groups.
Granted that the scientists still have their rigid hierarchies and lineages to slow them down, but even so, just the fact that ideas are out in public and being discussed at levels that never happened within the public before (where could I have found anyone to discuss nutrition with at Quentin's level in my small rural village without the Internet?)
--Jenny
http://www.phlaunt.com/diabetes Diabetes Info
http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood Sugar Under Control
guy - 06 Mar 2006 04:44 GMT As far as I know we do not know the cause of most diabetes. Plenty of speculators. Studies are no more valid than the person in control of the group. Diabetes is a tough nUt. Probably many causes of the syndrome.
IN real science, demand all you want. speculate all you want. We have very few answers that are firm.
Come back in 50 years and ask again Speculation is for drunkS on his bar stool.
I have some doubt that we are serious about finding the causes of any diabetes I am leaning toward --- a serious effort to turn our misfortune into a cash cow. THis is based on some conversations with the medical community.
30 years ago I thought "no problem,". I had a lot to learn.
So easy to write crap---so hard to write about something that is so complex. SOMEDAY.
Guy
>Chris Malcolm wrote:. >> [quoted text clipped - 52 lines] >http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood >Sugar Under Control Chris Malcolm - 08 Mar 2006 12:26 GMT In alt.support.diabetes Jenny <lottadata@hotmail.com> wrote:
> Chris Malcolm wrote:. >> [quoted text clipped - 4 lines] >> this newsgroup between what me might call the orthodox and the >> exploratory.
> I wonder how the openness of the web will impact the process that Kuhn > described so well. An interesting question.
> Just today, for example, I saw an article in the mainstream media > pointing to a bunch of studies that make it very clear that the high [quoted text clipped - 5 lines] > article also gave equal space to the apologists for the soda industry, > which could be the subject of a whole nother thread). They could have meant that the idea had now become accepted by all the researchers worth listening to, and the rest are old fogeys who can safely be ignored :-) If that is the case, it wouldn't surprise me if it took another several years before the grip of the old fogeys on positions of institutional authority had slackened off. A professor who sits on several research funding committees, reviews for many journals and is on the editorial baord of some of them, and who decides what research will and will not take place in his own department, is a very powerful opponent of a new idea he doesn't like. Quite apart from his official powers, he can pull many strings.
> But what struck me was that I'd read speculations about sodas containing > high fructose corn syrup being linked to the obesity epidemic least 5 [quoted text clipped - 3 lines] > that in some parts of Europe sodas still were made with sugar and that > obesity was not as prevalent there.
> Does the web discussion of these topics somehow leak through? We all > know that there are hundreds of readers for everyone who posts online. I worked in a science which has been using the web and newsgroups for longer than any other -- computer science and artificial intelligence. Whenever I've trespassed into other realms, I've been surpised by how many scientists scorned the web as something that their students wasted far too much of their time on. There's a lot less of that around today than there was five years ago, but there's still a lot of it.
I suspect that the time lags in the acceptance of a new idea, however, are far more to do with human psychology than the speed of publication and dissemination of the ideas. In my own field, highly populated with computer geeks who are always pushing the frontiers of computer technology, I've watched a revolutionary idea start being passed around by email and photocopy because it was so critical of established ideas nobody would publish it. That was in 1985. It took about ten years for it become widely enough established as a minority point of view that it had a conference and journal in which it featured heavily as the general view. Today it features less controversially in a number of conferences and journals and has become a reasonally respectable point of view, although there are still plenty who think it is misguided.
Having been part of that in my own small way, and knowing many of the main players, I think today's latest publication methods, such as fast-track on-line peer-reviewed web journals, blog of working lab notes and meetings, etc., might have speeded things up a little, but not much. The crucial delays were such things as young radical researchers acquiring tenured professorships and being able to support big research teams, host conferences, etc..
> In a similar manner, the diet advice that has helped us diabetics get > control was being posted online 7 years ago, at a time when those of us [quoted text clipped - 3 lines] > discussion has had an impact on people more plugged into the science > mainstream. Unfortunately by the time that many medical researches were beginning to look at newsgroups, AOL was starting its great experiment to see if millions of morons on connected keyboards might accidentally create a good idea. By the time that AOL got scared of being sued and pulled out of newsgroups, most scientists had been driven away from them. Even in CS and AI few scientists think of checking out a newsgroup, and although their students often romp about in the chattier newsgroups, few realise that some of them can be a useful scientific resource. They're now generally regarded as far too polluted by idiots and trolls to be any use.
But it only takes a local opinion former to spot something for it to become broadcast in his or her local group. So the influence of newsgroup debates is rather larger than you might expect from the number of scientists who make a point of consulting them, although a lot smaller than we might hope. But note that none of us here are original researchers in the field. The stuff we read and discuss is published and discussed elsewhere, in conferences, journals, and lab coffee rooms.
> Granted that the scientists still have their rigid hierarchies and > lineages to slow them down, but even so, just the fact that ideas are > out in public and being discussed at levels that never happened within > the public before (where could I have found anyone to discuss nutrition > with at Quentin's level in my small rural village without the Internet?) I agree. I think that newsgroups such as this one are due to begin having a new and much larger effect, because of the number of patients they are educating. Doctors are having to come to terms with a growing number of web savvy patients, who will turn up at the next meeting with three papers which contradict the doctor's advice. Cash strapped health sevices are thinking of ways of saving money by using computer-based patient support and information systems. Some of them are discovering that there are some existing good web sites and newsgroups. There are studies being done to help them decide whether they dare expose their patients to our amateurish advice :-)
That's why I did that recent survery, and why I wrote to them to correct their impression of what this newsgroup was useful for.
 Signature Chris Malcolm cam@infirmatics.ed.ac.uk +44 (0)131 651 3445 DoD #205 IPAB, Informatics, JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK [http://www.dai.ed.ac.uk/homes/cam/]
ted rosenberg - 06 Mar 2006 14:40 GMT > In alt.support.diabetes Bernard Peek <bap@shrdlu.com> wrote: > [quoted text clipped - 44 lines] > this newsgroup between what me might call the orthodox and the > exploratory. I am sorry, but you are WRONG Nutrition studies are almost university worthless, and, the inevitable results, after many many years of studies is that, except for the simplest items, all diet changes are meaningless. I am afraid I can't find the cite at the moment, but there is some serious mathematical work on the invalidity of diet studies in general.
We are full of the idiotic conclusions drawn from diet studies. 1) Chloresteral in your diet is bad - WRONG 2) Fiber in your diet helps prevent [insert here] - NOT 3) A low fat diet prevents [insert here] - in a pigs eye I could go on, but why bother
Yes, it SEEMS that trans fats may not be good for you, but the evidence is VERY thin. And, of course, it IS clear that deficiencies in lots of things, from salt to trace elements, WILL not be good for you.
Paul - 06 Mar 2006 18:57 GMT >Nutrition studies are almost university worthless, How true.
If you want to know whether or not a food is good for you, you simply need to pick the correct year in the learned journals and you will find the answer you want.
And if you had simply ignored all the advice and stuck to a properly balanced diet (i.e. variety in both food groups and food within groups), then assuming you had no other health problems you would have been fine (statistically).
>And, of course, it IS clear that deficiencies in lots of >things, from salt to trace elements, WILL not be good for you. That's something I always tell people when the start spouting about the latest health fad.
If we cut out all the things that they witter on about being bad for us, we would die of malnutrition.
Far more person-years have been gained by eating plenty of bread, meat and dairy products than have ever been lost because of complications caused by eating them.
Priscilla Ballou - 05 Mar 2006 19:09 GMT > >If the history of science is any guide, when this Pasteur comes along > >with his new fangled ideas he may well at first be derided and mocked [quoted text clipped - 11 lines] > happened more often you wouldn't hear about them unless you read the > relevant journals. Which journals do you usually read? Hoo boy, are you poking the wrong one! LOL
Go get 'em, Chris!
Priscilla
Susan - 05 Mar 2006 19:27 GMT > Hoo boy, are you poking the wrong one! LOL > > Go get 'em, Chris! ROFL! I'm gonna need a bowl of virtual popcorn to watch this one. :-)
Susan
Bernard Peek - 05 Mar 2006 20:27 GMT >x-no-archive: yes > >> Hoo boy, are you poking the wrong one! LOL >> Go get 'em, Chris! > >ROFL! I'm gonna need a bowl of virtual popcorn to watch this one. :-) I've just taken on an economics professor in another newsgroup. I've been practising :-)
 Signature Bernard Peek London, UK. DBA, Manager, Trainer & Author.
ted rosenberg - 06 Mar 2006 14:29 GMT >> If the history of science is any guide, when this Pasteur comes along >> with his new fangled ideas he may well at first be derided and mocked [quoted text clipped - 11 lines] > happened more often you wouldn't hear about them unless you read the > relevant journals. Which journals do you usually read? At the time, individual developments were more common. Pasteur was a genius, and he was untrained in medicine.
Science is SUPPOSED to resist miracle cures. New advances need to be proved and verified with independent tests, otherwise every crackpot idea would be adopted. By FAR, most are worthless, in fact, most ideas which look good in early trials, and which have a single positive study are worthless
ted rosenberg - 05 Mar 2006 14:07 GMT > In alt.support.diabetes Peter C <peterc_2003@europe.com> wrote: > [quoted text clipped - 3 lines] & |
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