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Medical Forum / Diseases and Disorders / Diabetes / February 2006

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Metformin Results

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Alfred Kaufmann - 24 Feb 2006 04:23 GMT
I have been taking 2 500mg metformin tablets daily for a month now and
according to my glucose meter my trend over that period is going up.
That is not the result I want.

I have been reading some literature on the Internet that leads me to
believe I should increase my dosage to 1500mg per day for a week and
if that does not produce the desired results then go to 2000mg per
day.  According to the literature the maximum daily dose is 2250mg per
day.   If I don't notice any significant reduction in my blood glucose
reading over the next 2 weeks then I really think I should get off
Metformin.

If Metformin does not work for me maybe there is some other drug that
will work for me?

I want to hear if I am doing something that I should not be doing. A
lot of the Type II diabetes stuff, diet and exercise is trial and
error done by yourself and I think this falls into that category.
Please don't tell me to consult with my doctor, he is in Africa for 4
weeks and I do not want to wait that long.  I can give him the graphs
when he gets back.

Al

noneyabusiness - 24 Feb 2006 05:36 GMT
>I have been taking 2 500mg metformin tablets daily for a month now and
>according to my glucose meter my trend over that period is going up.
[quoted text clipped - 19 lines]
>
>Al

I think you've just barely given the metformin enough time to get
started. If you've become used to it so far, maybe start taking 3 a
day for a month THEN see where you are at.

It takes time.

I assume you ARE trying to keep your diet under control and are
exercising, right?

...
Alfred Kaufmann - 24 Feb 2006 06:50 GMT
>>I have been taking 2 500mg metformin tablets daily for a month now and
>>according to my glucose meter my trend over that period is going up.
[quoted text clipped - 28 lines]
>I assume you ARE trying to keep your diet under control and are
>exercising, right?

Yes I am controlling my diet and I am exercising.  I have cut down on
food and doubled my exercise time.  Right now my blood sugar is what I
consider excellent for the night 5.8.  Of course now I don't know if
the increased Metformin dosage had anything to do with this.

Al
Alan S - 24 Feb 2006 08:30 GMT
>>I assume you ARE trying to keep your diet under control and are
>>exercising, right?
[quoted text clipped - 5 lines]
>
>Al

Exactly which food have you cut down on? Fats, Protein,
Carbohydrates?

What was your reading an hour after breakfast this morning?
I think you'll find this link very interesting:
http://www.alt-support-diabetes.org/NewlyDiagnosed.htm

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
Signature

Everything in Moderation - Except Laughter.

Alfred Kaufmann - 25 Feb 2006 21:53 GMT
>>>I assume you ARE trying to keep your diet under control and are
>>>exercising, right?
[quoted text clipped - 8 lines]
>Exactly which food have you cut down on? Fats, Protein,
>Carbohydrates?

I just eat less in general.  I am not about to eat things I don't like
or avoid foods I do like, although I have stopped buying some foods. I
would rather exercise more.

>What was your reading an hour after breakfast this morning?

Usually I only test before eating and before bedtime but you caught me
at the correct time - 1 hour after breakfast it was 9.2.  It tells me
I had a good breakfast - 3 slices of bacon, 1 eggs, 1 slice of toast,
small glass of orange juice and 2 cups of black coffee.  By lunch time
it will probably be just above 6.2.

>I think you'll find this link very interesting:
>http://www.alt-support-diabetes.org/NewlyDiagnosed.htm

Thanks for the link but I have been dieting and exercising for 10
years now, just newly on drugs.

Al
Ozgirl - 26 Feb 2006 00:17 GMT
> Usually I only test before eating and before bedtime but you caught me
> at the correct time - 1 hour after breakfast it was 9.2.  It tells me
> I had a good breakfast - 3 slices of bacon, 1 eggs, 1 slice of toast,
> small glass of orange juice and 2 cups of black coffee.  By lunch time
> it will probably be just above 6.2.

A good breakfast? A 9.2 after breakfast is a shocking
number. You should have been less than the 6.2 after
breakfast not before lunch.

>>I think you'll find this link very interesting:
>>http://www.alt-support-diabetes.org/NewlyDiagnosed.htm
>
> Thanks for the link but I have been dieting and exercising for 10
> years now, just newly on drugs.

From that breakfast, I hate to say it, but you haven't a
real clue about diet. Expecting drugs to compensate for a
diabetic unfriendly diet is pie in the sky. Nothing short of
insulin is going to help you if you don't want to modify
your diet. Some of the most serious complications start with
blood sugars of 7.0. I am not blaming you, you have clearly
been misinformed, but it is never too late to start
learning. That above link would help both newly diagnosed
AND longer term diabetics who have been misinformed.

At breakfast we are at our most insulin resistant (carb
sensitive), the juice is a big no no. Juice is used to get
someone out of hypo territory, fast! At breakfast a lot of
us can't eat more than just protein. A rise to 9.2 (which
could even have gone higher if you had kept testing) is just
plain and simply way too high.  What are your lab numbers.
for cholesterol, triglycerides etc?
David - 26 Feb 2006 01:18 GMT
> Usually I only test before eating and before bedtime but you caught me
> at the correct time - 1 hour after breakfast it was 9.2.  It tells me
> I had a good breakfast - 3 slices of bacon, 1 eggs, 1 slice of toast,
> small glass of orange juice and 2 cups of black coffee.  By lunch time
> it will probably be just above 6.2.

> Al

[tough love "on"] You are "controlling" your diet AND YOU DRINK OJ?  go
back to the dietician and get retrained!  You can't drink OJ and not
expect your bg's to go UP!  [Tough love off]

Dave
Alan S - 26 Feb 2006 04:31 GMT
>>>>I assume you ARE trying to keep your diet under control and are
>>>>exercising, right?
[quoted text clipped - 28 lines]
>
>Al

Hi Alfred

"10 years now, just newly on drugs." What are your lipid
numbers like? What is your BP?

It's your life mate. I accept that I may be a totally wrong
alarmist. If I am, at worst I will prick myself a few times
more than I really needed to for tests, and restrict my diet
and lifestyle a little. If I'm not, I'm going to live a lot
more complication free-years than I would have. That's the
choice I've made.

When you say "I am not about to eat things I don't like or
avoid foods I do like" you have made a personal choice.
That's fair enough - we all have to make such choices in
life.

But everything has a price. When we make choices, it's wise
to have all the facts first, if you can.

Try adding this information to your knowledge base:
http://www.phlaunt.com/diabetes/14045678.php
I notice you don't actually read links, so I'll presume
Jenny's permission and repeat a little bit from that:
"These studies, some of which are not cited in the AACE
guidelines, make a cogent case that post-meal blood sugars
of 140 mg/dl (7.8 mmol/L) and higher and fasting blood
sugars over 100 mg/dl (5.6 mmol/L) cause permanent organ
damage and cause diabetes to progress."

For example, if it was me, I wouldn't be complacently saying
"1 hour after breakfast it was 9.2.  It tells me I had a
good breakfast".

What it tells me is that you ate a bloody terrible breakfast
which spiked you to 9.2 mmol/L or 166 mg/dl. A number that
was totally unnecessary and you've probably been getting
similar numbers for ten years. I will absolutely guarantee
you that simply by dropping the "small" orange juice you'll
drop that by at least a mmol(18), probably more, for
starters. However, I do accept that if you have no
complications, no cardio-vascular problems and are in fine
health - then you've proved in a scientific experiment on
yourself that you, personally, can do that for ten years
without harm.

The bacon and egg were fine - but the toast may not be. You
could test to find out.

As I said, it's your choice to continue in the "ostrich"
method of management or not. If you do, I have to wonder why
you test at all if you aren't going to change anything when
you see a bad result, or even accept that it WAS a bad
result.

Again, I'll suggest that you read Jennifer's advice at
http://jennifer.flyingrat.net/

I'll leave it at that, and honestly wish you the very best
of health.

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
Signature

Everything in Moderation - Except Laughter.

Nicky - 26 Feb 2006 11:58 GMT
> Usually I only test before eating and before bedtime but you caught me
> at the correct time - 1 hour after breakfast it was 9.2.  It tells me
> I had a good breakfast - 3 slices of bacon, 1 eggs, 1 slice of toast,
> small glass of orange juice and 2 cups of black coffee.  By lunch time
> it will probably be just above 6.2.

Good grief! It tells me you need to drop the OJ altogether (you do know it's
pretty well the fastest way to treat a hypo? - your 15 min reading would
probably have been even higher) and possibly throw the toast away too. You
may get away with a lower carb bread?

My 1hr pp after a 2-egg and cheese omelette this morning was 5.6.

You start to damage yourself around the 7.8 mark. An occasional foray is
probably OK - but you've likely been up that way for years.

If your doctor is telling you a 6+ A1c is OK, btw, he's behind the times.
The American college of endocrinologists - AACE - moved the goalposts to 6-
a couple of years ago.

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

Slap - 26 Feb 2006 14:54 GMT
> If your doctor is telling you a 6+ A1c is OK, btw, he's behind the times.
> The American college of endocrinologists - AACE - moved the goalposts to 6-
> a couple of years ago.
>
> Nicky.

The AACE sounds like some kind of radical group.  I call them "subtractors".
You take well researched data pull a point or so off it and make the world a
better place.

The CDA still says at least <7 (2005 Diabetes Report).  A small quote from
the 45 page report...

"Healthcare professionals are asked to get their patients with diabetes to
the A1C target of 7 percent or lower as soon as possible.The best available
research strongly indicates that A1C levels of lower than 7 percent
significantly prevents the onset of serious complications, including heart
attack, stroke, blindness, amputation or kidney disease."

Does the AACE have better research data than the CDA.  Where does your
Diabetes Association stand on this?  What are they recommending?

--
Dave, T2, Canada
Alan S - 26 Feb 2006 20:59 GMT
Was "Metformin Results"

>> If your doctor is telling you a 6+ A1c is OK, btw, he's behind the times.
>> The American college of endocrinologists - AACE - moved the goalposts to
[quoted text clipped - 17 lines]
>Does the AACE have better research data than the CDA.  Where does your
>Diabetes Association stand on this?  What are they recommending?

Hi Dave

The AACE is "some kind of radical group"? In that case we
need more radicals.

You call them "subtractors"? I call them professionals - as
against bureaucrats.

Their history page is at http://www.aace.com/org/history.php
Some snippets:

"The American Association of Clinical Endocrinologists
(AACE) was founded in 1991 by a visionary group of leaders
to serve as the active voice for clinical endocrinologists."

"The impetus behind AACE's efforts has always been quality
and cost-effective patient care for those with endocrine
diseases and disorders. The need for AACE was evidenced by
the phenomenal growth in membership in the first year with
the receipt of 1,162 membership applications."

"Today, AACE has over 5200 members throughout the United
States and in 84 foreign countries."

How many clinical endocrinologists do you think are actually
involved in the decision-making process for setting the
guidelines for the management of diabetes at the CDA, or the
ADA, or Diabetes Australia or the NHS? Which organisations
must remain most mindful of government policies and/or
sponsor's wishes, and which is an organisation of specialist
professionals? If I was forced to make a decision on which
organisation I'd listen to first, it would be a no-brainer.

Incidentally - they all have sponsors, so form your own
opinion there by comparing:
AACE:
http://www.aace.com/org/cap/capdirectory.php
ADA:
http://www.diabetes.org/support-the-cause/our-national-corporate-sponsors.jsp
I couldn't find the list for the others - I'd be interested
to see it if you can find it. I do know that the CEO of
McDonalds was invited to the board of Diabetes Australia.

Now, on A1c, if you go to
http://www.aace.com/public/awareness/stateofdiabetes/index.php
and download the Adobe pdf fact sheet titled Facts About A1C
http://www.aace.com/public/awareness/stateofdiabetes/FactsAboutA1C.pdf
You'll find this in the detail:

"What is the target level for A1C?
The American Association of Clinical Endocrinologists (AACE)
recommends that people with type 2 diabetes reach an A1C
goal of 6.5% or less. Achieving this goal is important,
since every 1% increase above 6% elevates the risk of
diabetes-related complications such as stroke, heart attack
and loss of limbs. It is important, however, that people
with type 2 diabetes speak with their doctor or other
healthcare professional about setting their own personal A1C
goal."

Those changes appeared after the AACE 14th Annual Meeting
and Clinical Congress in May 2005.

Nicky may have prematurely moved the goalposts from 6.5% to
6% - but I'm sure that's only a matter of time too.

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
Signature

Everything in Moderation - Except Laughter.

Slap - 26 Feb 2006 23:07 GMT
> Was "Metformin Results"
>
[quoted text clipped - 58 lines]
> http://www.aace.com/org/cap/capdirectory.php
> ADA:

http://www.diabetes.org/support-the-cause/our-national-corporate-sponsors.jsp
> I couldn't find the list for the others - I'd be interested
> to see it if you can find it. I do know that the CEO of
[quoted text clipped - 16 lines]
> healthcare professional about setting their own personal A1C
> goal."

That sounds quite similiar to the CDA quote.

> Those changes appeared after the AACE 14th Annual Meeting
> and Clinical Congress in May 2005.
>
> Nicky may have prematurely moved the goalposts from 6.5% to
> 6% - but I'm sure that's only a matter of time too.

From your posted date above she also moved the time line by 1-1/2 years.
The CDA report (December 7/05) suggests <7.

I'll have to read up on your supplied links but what I see...

The CDA gets together with ADA and all the other GOV. agencies.  They
probably pool their research and come up with some numbers.

What is a group such as the AACE supposed to do?  They want to justify their
existence... no?  They want to be/appear better... such as a University that
tightens up the criteria to gain entrance.  A new town council has to do
something so they make new laws, even tho the town has done great for the
past 10 years.

Anyway there can't possibly be anything wrong with getting your A1C <6
(mines at 6.1) I just wonder why the numbers posted on this group by a dozen
or so are always tightened up some what.  We go from 2 hr. after meal
testing to 1 hr.  From testing 4 times a day to 8 or more times a day.
Common sense (I guess that's OK) is often the reason given for tightening up
these figures.

I live in Edmonton, Alberta Canada and we have a leading edge Diabetes
Research Team here. I'll have to go see what they are up to but I can't see
us being behind and in fact they are probably right up front.

--
Dave
TigerLily - 26 Feb 2006 23:16 GMT
Dave....... i'm just south of you in Calgary,
Alberta

my endo purports that 2 hour pp testing is
required

my GP wants my A1c to be below 6.0

i'm sure we aren't that far off from each
other...... it's just that our Dr's only Rx what
they think we will reach for

my endo, does have a variation on the 10 times per
day testing to still get the 2 hour pp
readings........ with 4 to 6 tests per day

kate
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"Slap" <> wrote in message o...

> Anyway there can't possibly be anything wrong with getting your A1C <6
> (mines at 6.1) I just wonder why the numbers posted on this group by a dozen
[quoted text clipped - 9 lines]
> --
> Dave
Slap - 26 Feb 2006 23:48 GMT
> Dave....... i'm just south of you in Calgary,
> Alberta
[quoted text clipped - 3 lines]
>
> my GP wants my A1c to be below 6.0

I was just at the Clinical Practice Guidelines site.  If you look at #3...
well they suggest Nicky and Alan are with it.

Recommendations
1. Glycemic targets must be individualized; however, therapy in most
patients with type 1 or type 2 diabetes should be targeted to achieve an A1C
?7.0% in order to reduce the risk of microvascular [Grade A, Level 1A (1,3)]
and macrovascular complications [Grade C, Level 3 (5)].

2. To achieve an A1C ?7.0%, patients with type 1 or type 2 diabetes should
aim for FPG or preprandial PG targets of 4.0 to 7.0 mmol/L and 2-hour
postprandial PG targets of 5.0 to 10.0 mmol/L [Grade B, Level 2 (1-3)].

3. If it can be safely achieved, lowering PG targets toward the normal range
should be considered [Grade C, Level 3 (4,5,8,10)]:

·      A1C ?6.0% [Grade D, Consensus];

·      FPG/preprandial PG: 4.0 to 6.0 mmol/L [Grade D, Consensus]; and

·      2-hour postprandial PG: 5.0 to 8.0 mmol/L [Grade D, Consensus].
Alan S - 27 Feb 2006 00:11 GMT
>> Was "Metformin Results"
>>
[quoted text clipped - 121 lines]
>Research Team here. I'll have to go see what they are up to but I can't see
>us being behind and in fact they are probably right up front.

Just on a couple of your points. I never implied that any of
our countries are ahead or behind - we all have our good
research people. I don't forget Banting and Best. A lot of
cutting-edge research is happening in the smaller countries
where there is sometimes more freedom to utilise areas like
stem-cell research, and different emphasis because of local
needs.

If you google you'll see a lot of previous discussions here
on 2hr vs 1hr post-prandial. To put it simply, my view is
that we should test for the peak spike, not the resting
level, which for many of us is closer to one-hour than two.
But that's another discussion.

And I don't think the AACE has any need to justify their
existence - read that history page link.

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
Signature

Everything in Moderation - Except Laughter.

Jennifer - 27 Feb 2006 01:18 GMT
I guess I don't understand.

If you're not a T1 or insulin using T2 who is struggling with possibly
dangerous hypos... why wouldn't you aim for non-diabetic numbers?

You may not get there, but if you reach that goal, it can only benefit
your continued health.

Jennifer

>>Was "Metformin Results"
>>
[quoted text clipped - 141 lines]
> --
> Dave
Slap - 27 Feb 2006 01:28 GMT
> I guess I don't understand.
>
[quoted text clipped - 16 lines]
> > Research Team here. I'll have to go see what they are up to but I can't see
> > us being behind and in fact they are probably right up front.

Yes, that's what I said.
Nicky - 27 Feb 2006 17:46 GMT
> I live in Edmonton, Alberta Canada and we have a leading edge Diabetes
> Research Team here. I'll have to go see what they are up to but I can't
> see
> us being behind and in fact they are probably right up front.

They may well be, Dave - but how long before the general practitioner down
the road catches up? What do your guys do, a 7-year training like ours?
That's AFTER the research is accepted into the curriculum.

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

Slap - 27 Feb 2006 18:29 GMT
> > I live in Edmonton, Alberta Canada and we have a leading edge Diabetes
> > Research Team here. I'll have to go see what they are up to but I can't
[quoted text clipped - 6 lines]
>
> Nicky.

This is true.

I did check, and what they have being doing is the transplanting islet cells
from 'baby' pigs.

In 2000 the Edmonton team pioneered islet cell transplants (from the
pancreas of a dead body into the liver of a diabetic, where they take root
and begin producing insulin).  About 90 people  have received this treatment
at the U of A in Edmonton.

Back to the 'baby' pigs.  Today's newspaper...
"University of Alberta researchers Ray Rajotte and Greg Korbutt have just
published a study showing that insulin-producing islet cells from 'baby'
pigs can be successfully transplanted into diabetic macaque monkeys and cure
their diabetes."

This is NOT the study published a week ago that was done at the University
of Minnesota.  They used 'adult' pigs in that study.  'Baby' cells could
continue to produce more cells after transplant; adult cells won't do that.

Full story is here...
http://www.canada.com/edmontonjournal/news/story.html?id=5bef8d1e-77f9-4d7d-8eaf
-7abbba82319c


There is a bit to go but when Diabetes is beat, the Edmonton research team
will be there in some way, shape or form.

--
Dave, T2, Canada
Nicky - 27 Feb 2006 18:37 GMT
> Full story is here...
> http://www.canada.com/edmontonjournal/news/story.html?id=5bef8d1e-77f9-4d7d-8eaf
-7abbba82319c

>
> There is a bit to go but when Diabetes is beat, the Edmonton research team
> will be there in some way, shape or form.

Cool!

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

Jefferson - 27 Feb 2006 22:55 GMT
Dave:

> Back to the 'baby' pigs.  Today's newspaper...
> "University of Alberta researchers Ray Rajotte and Greg Korbutt have just
[quoted text clipped - 5 lines]
> of Minnesota.  They used 'adult' pigs in that study.  'Baby' cells could
> continue to produce more cells after transplant; adult cells won't do that.

Pig beta cells were transplanted into humans in Mexico by a former New
Zealand doctor.  The problem is communication of diseases between species.

Frank
Slap - 27 Feb 2006 23:26 GMT
> Pig beta cells were transplanted into humans in Mexico by a former New
> Zealand doctor.  The problem is communication of diseases between species.
>
> Frank

Not if you read the article...  well to the monkeys anyway.  Also in the
article they are hoping for human stem cells but that is a touchy subject
that may take years.

"Another important finding of the U of A study, Rajotte says, is that the
transplants didn't transmit pig viruses into the monkeys."

http://www.canada.com/edmontonjournal/news/story.html?id=5bef8d1e-77f9-4d7d-8eaf
-7abbba82319c

Priscilla H. Ballou - 24 Feb 2006 21:22 GMT
> Yes I am controlling my diet and I am exercising.  I have cut down on
> food and doubled my exercise time.  Right now my blood sugar is what I
> consider excellent for the night 5.8.  Of course now I don't know if
> the increased Metformin dosage had anything to do with this.

What is your BG at 1 hour and 2 hours post-prandial?  That's a better
gauge.

Priscilla
Alfred Kaufmann - 25 Feb 2006 22:01 GMT
>> Yes I am controlling my diet and I am exercising.  I have cut down on
>> food and doubled my exercise time.  Right now my blood sugar is what I
[quoted text clipped - 3 lines]
>What is your BG at 1 hour and 2 hours post-prandial?  That's a better
>gauge.

I would think your blood sugar depends what you had to eat, how much
you ate and what sort of activity you had.  What would taking these
reading 1 and 2 hours after eating tell you?

I do know which foods will cause my blood glucose to jump up and I try
to cut down on them.

Al
 
Susan - 25 Feb 2006 22:05 GMT
> I would think your blood sugar depends what you had to eat, how much
> you ate and what sort of activity you had.

True.

  What would taking these
> reading 1 and 2 hours after eating tell you?

It would tell you how well you're controlling your diabetes, whether
you're spiking into the ranges that are known to cause cellular damage,
and exactly which foods or meals are interfering with the kind of
control that prevents diabetic complications.

Susan
Jennifer - 25 Feb 2006 23:03 GMT
> I would think your blood sugar depends what you had to eat, how much
> you ate and what sort of activity you had.  What would taking these
> reading 1 and 2 hours after eating tell you?

It would tell you EXACTLY what you're saying.

Did what you ate, how much you ate, and what sort of activity you had
keep your BG in line after your meal.

Or do you have to adjust that meal next time to acheive your goals.

It's like driving a car without looking at the speedometer.  Sure you
can look out the window and guess how quickly you're passing the
trees... and you can assume that the headwinds you're traveling into are
affecting your speed... but you can't really know unless you look at the
numbers on your dash.  Just as you can't REALLY know how the food you
eat and the exercise you do is affecting your blood glucose unless you
look at the numbers on your meter.  After the meal.

If you really want to know if your new med is doing anything, you'll
need to test a lot more often to see if it's having the affect your
doctor is after.

Here's the advice I give those that want to see how their current
treatment is working for them.  Which, after reading your posts you seem
to want to do.

You might want to try some  experiments.

First:  Eat whatever you've been
currently eating... but write it all down.
Test yourself at the following times:

Upon waking (fasting)
1 hour after each meal
2 hours after each meal
At bedtime

That means 8 x each day.  What you will discover by this is how long
after a meal your highest reading comes... and how fast you return to
"normal".  Also, you may see that a meal that included bread, fruit or
other carbs gives you a higher reading.

Then for the next few days, try to curb your carbs.  Eliminate breads,
cereals, rices, beans, any wheat products, potato, corn, fruit... get all
your carbs from veggies.  Test at the same schedule above.

If you try this for a few days, you may find some pretty damn good
readings.  It's worth a few days to discover.

Eventually you can slowly add back carbs until you see them affecting your
meter.

The thing about this disease... though we share much in common and we
need to
follow certain guidelines... in the end, each of our bodies dictate our
treatment and our success.

The closer we get to non-diabetic numbers, the greater chance we have of
avoiding horrible complications.  The key here is AIM... I know that
everyone is at a different point in their disease... and it is progressive.
But, if we aim for the best numbers and do our best, we give ourselves the
best shot at heath we've got.
That's all we can do.

Here's my opinion on what numbers to aim for, they are non-diabetic numbers.

FBG                          under 100
One hour after meals       under 140
Two hours after meals     under 120

or for those in the mmol parts of the world:

Fasting                              Under 6
One hour after meals         Under 8
Two hours after meals       Under 6.5

And an A1c of under 6.

Recent studies have indicated that the most important numbers are your
"after meal" numbers. They may be the most indicative of future
complications, especially heart problems.

Listen to your doctor, but you are the leader of your diabetic
care team.  While his /her advice is learned, it is not absolute.   You
will end up knowing much more about your body and how it's handling
diabetes than your doctor will.   Your meter is your best weapon.

Just remember, we're not in a race or a competition with anyone but
ourselves... Play around with your food plan... TEST TEST TEST.  Learn what
foods cause spikes, what foods cause cravings... Use your body as a science
experiment.

Best of luck!

Jennifer
Julie Bove - 24 Feb 2006 21:34 GMT
> Yes I am controlling my diet and I am exercising.  I have cut down on
> food and doubled my exercise time.  Right now my blood sugar is what I
> consider excellent for the night 5.8.  Of course now I don't know if
> the increased Metformin dosage had anything to do with this.

"Cut down on food?"  What does that mean?  And what does "for the night"
mean?  When exactly are you testing your BG?  And what are you eating?  Can
you give us a sample meal or two?

Signature

See my webpage:
http://mysite.verizon.net/juliebove/index.htm

Alfred Kaufmann - 25 Feb 2006 22:14 GMT
>> Yes I am controlling my diet and I am exercising.  I have cut down on
>> food and doubled my exercise time.  Right now my blood sugar is what I
>> consider excellent for the night 5.8.  Of course now I don't know if
>> the increased Metformin dosage had anything to do with this.
>
>"Cut down on food?"  What does that mean?

It means eating less in general.

>  And what does "for the night" mean

Before bedtime.  If it is higher than 8 it means I will be exercising
to get it down.

> When exactly are you testing your BG?

Before meals and before bedtime.

>  And what are you eating?  Can
>you give us a sample meal or two?

Dinner last night was 4 slices of smoked ham wrapped around four
pickles, 9 little pieces of sacchetti with emmental cheese covered
with tomato pasta sauce and one glass of red wine.

The day before, large slice of meatloaf, potato, creamed spinach and
one glass of red wine.

Al
Ozgirl - 24 Feb 2006 08:25 GMT
> I have been taking 2 500mg metformin tablets daily for a month now and
> according to my glucose meter my trend over that period is going up.
[quoted text clipped - 12 lines]
>
> I want to hear if I am doing something that I should not be doing.

What is your current diet and exercise? No diabetic drug is
a magic pill. It takes a combination of diet, exercise and
meds. No one can say what you are doing wrong, if anything
until you supply more information. How often do you eat,
what do you eat (specifically carbs) what are your fasting
numbers, your pre meal numbers, your post meal numbers. Are
you overweight? Do you have high blood pressure and high
cholesterol levels? Are you on any other meds?
Alfred Kaufmann - 25 Feb 2006 22:22 GMT
>What is your current diet

I would have to write a book!

>  and exercise?

That is a bit easier, mainly fast walking 10,000 plus steps every
second day.  Now I try to get out everyday.  On nice days I have no
problem doing 25,000 plus steps.

> No diabetic drug is
>a magic pill. It takes a combination of diet, exercise and
[quoted text clipped - 4 lines]
>you overweight? Do you have high blood pressure and high
>cholesterol levels? Are you on any other meds?

A lot of questions and I did start three medications all at the same
time.  Metformin, a pill of high blood pressure and an
anti-inflammatory.

I was on the anti-inflammatory for 9 days and I had to quit taking it
because of the stomach problem it caused.

I have taken off 45 pound since I was first diagnosed which is what my
doctor recommended at the time.  For my height I have the correct
weight but I would not feel bad if I could convert another 20 pounds
of fat into muscle. :-)

Al
Ozgirl - 26 Feb 2006 00:23 GMT
>>What is your current diet
>
[quoted text clipped - 18 lines]
> time.  Metformin, a pill of high blood pressure and an
> anti-inflammatory.

I just posted a message regarding your breakfast.

I was put on a BP med at diagnosis - 6 years ago, that has
been the norm for quite a long time. I think I am getting a
picture of your treatment by your docotr. It is archaic,
old-fashioned, whatever. There has been a huge amount of
research done in the past 10 years and most doctors are on
the ball. Perhaps you haven't been to your doctor for a long
time until recently?

> I was on the anti-inflammatory for 9 days and I had to quit taking it
> because of the stomach problem it caused.
[quoted text clipped - 3 lines]
> weight but I would not feel bad if I could convert another 20 pounds
> of fat into muscle. :-)

That would be an enormous help. Weight loss and/or creating
muscle does marvellous things to insulin resistance.
Slap - 24 Feb 2006 08:35 GMT
> I have been taking 2 500mg metformin tablets daily for a month now and
> according to my glucose meter my trend over that period is going up.
> That is not the result I want.

Others will be around to discuss your diet.  Take the Metformin.  It is good
for you and your body.  Remember that.

Also it's not really magic.  Takes time and you can't, say, have a Metformin
and a piece of choclate cake.  Doesn't work that way.  You could have a
salad tho.

--
Dave, T2, Canada
Alfred Kaufmann - 25 Feb 2006 22:24 GMT
>> I have been taking 2 500mg metformin tablets daily for a month now and
>> according to my glucose meter my trend over that period is going up.
[quoted text clipped - 6 lines]
>and a piece of choclate cake.  Doesn't work that way.  You could have a
>salad tho.

Just a piece of chocolate cake? :-(  I do like salad too.

Al
Nicky - 24 Feb 2006 12:31 GMT
>I have been taking 2 500mg metformin tablets daily for a month now and
> according to my glucose meter my trend over that period is going up.
> That is not the result I want.

You could try increasing the metformin as you suggest. However, you don't
sound like you're doing post-meal testing - have you read this link? I found
it absolutely invaluable for controlling my diabetes.
http://www.alt-support-diabetes.org/Newly%20Diagnosed.htm

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

oldal4865 - 24 Feb 2006 12:37 GMT
Alfred Kaufmann wrote in message ...
>I have been taking 2 500mg metformin tablets daily for a month now and
>according to my glucose meter my trend over that period is going up.
[quoted text clipped - 19 lines]
>
>Al

The U.S. Physicians' Desk Reference recommends 1500 mg/day metformin as the
clinical maintenance dose and 2550 mg/day as the maximum prudent dose but
they also advice patients to "walk" the dose up to minimize G.I. problems.
I agree with your take on that  part  (that 2250 maximum dose  was a typo,
right?)

However,   but I disagree with some of your premises.

1.  From your other post:

". . . .Right now my blood sugar is what I consider excellent for the night
5.8. . ."

Sorry,  but if you are just checking fasting blood glucose  (FbG),  you are
missing a major part of the picture.    There is evidence that your
2-hour-after-eating blood glucose (2-hr-PP)     are more important than your
FbG.     IMO,   you cannot even start to evaluate the effectiveness of your
metformin until you have had a few weeks/months of charting 2-hr-PP.

2.  Another point of view that you haven't touched upon yet:

      About 80-90% of newly diagnosed T2 diabetics have high Insulin
Resistance

     High Insulin Resistance is associated with premature death from heart
attack

     Metformin is an anti-Insulin Resistance  Med

    Metformin reduces the very high risk of premature heart attack suffered
by many Type 2 diabetics.

IOW,   you are judging Metformin solely by its effect on your FbG when you
should also be very concerned about your risk of premature heart attack.

You can monitor that risk somewhat by following your cholesterol profiles.
High Insulin Resistance very often causes high triglycerides and low HDL
values in T2 Lipid panels.   That's a recipe for heart attack.     Metformin
improves those values.

Your Targets:    triglycerides/HDL ratio less than 3.0 in the U.S. mg/dL
system,   1.3 in the Rest-of-the-World mmol/L system

                        LDL/HDL ratio less than 4  (the lower the better)

                       Total Cholesterol/HDL  less than 4,   (the lower the
better)

(Umm. . . prudent diabetics keep records of their HbA1c,  blood pressure and
cholesterol profiles).

3.  If you want to add another diabetes med to your therapy,  by all means
negotiate with your doctor.   However,  don't stop taking metformin until
you are certain you have your Insulin Resistance in check.

Also,   note that there is mounting evidence that the beta cell insulin
stimulators  (Glucotrol,  Glicizide,  Amaryl,  Starlix,  Prandin)  tend to
damage beta cells and ultimately intensify the severity of the disease down
the road.   Not too big a problem if you're 75,  but not something to
embrace if you're 55.

There is also evidence that the sulfonylurea types of beta cell insulin
stimulators increase your risk of heart attack.

4.  While you're about it,   consider that certain lifestyle changes
themselves count almost as a "Miracle Drug"  for Type 2 diabetics,  i.e.

        a.  Lose fat lb
        b.  Gain muscle lb  (ugh. . .weight lifting)
        c.  Exercise every day,  the more vigorously the better
        d.  Ration your carbohydrate,  eat slowly-digesting carb,  spread
your daily carb over several small meals

Regards
 Old Al
Alfred Kaufmann - 25 Feb 2006 22:40 GMT
>Alfred Kaufmann wrote in message ...
>>I have been taking 2 500mg metformin tablets daily for a month now and
[quoted text clipped - 96 lines]
>Regards
>  Old Al

Thanks for the detailed information.  I hardly ever test fasting blood
glucose but do test before my meals and bedtime.

My A1c is 6.3% (below target) Cholesterol LDL is 2.44 (below target)
HDL is 4.1 (slightly above target) and my blood pressure systolic is
160 but I have white coat syndrome :-) , at home it tests below 130.

Right now I am taking 1500mg Metformin and I will keep that up for
just over a month and then I go in to get all these test done again.

I figure that by taking Metformin I should see some results.  If I
can't see any results then I have to question why I am on it.

Al
Ozgirl - 26 Feb 2006 00:26 GMT
> My A1c is 6.3% (below target) Cholesterol LDL is 2.44 (below target)
> HDL is 4.1 (slightly above target) and my blood pressure systolic is
[quoted text clipped - 5 lines]
> I figure that by taking Metformin I should see some results.  If I
> can't see any results then I have to question why I am on it.

A better target is to be below 6% A1c. Your doctor must have
seen a problem to prescribe Metformin. What is your at home
diastolic?
Alan S - 26 Feb 2006 04:38 GMT
>Thanks for the detailed information.  I hardly ever test fasting blood
>glucose but do test before my meals and bedtime.
[quoted text clipped - 10 lines]
>
>Al

I think that may be a transcription error Alfred, try HDL
1.4 - which is still quite good. What are the trigs?

From the other posts you've made mentioning your menu and
diet - I suspect that breakfast is your only real problem.
You asked what a one-hour test will tell you? Simply whether
the meal you ate, and the exercise since, kept your BGs in
reasonable territory. If not you change something next time.
Simple as that.

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
Signature

Everything in Moderation - Except Laughter.

Larry - 26 Feb 2006 16:47 GMT
Hello Oldal: Just wondering about Avandia as an insulin sensitizer.
Does this mean it is not an anti-Insulin Resistance drug like metformin
is?  Is insulin sensitization and IR two different concepts and
measured in different ways? Thanks for an answer.

Larry

> Alfred Kaufmann wrote in message ...
> >I have been taking 2 500mg metformin tablets daily for a month now and
[quoted text clipped - 96 lines]
> Regards
>   Old Al
Loretta Eisenberg - 24 Feb 2006 13:32 GMT
Al, every doctor has a doctor covering for him.  I would not advise you
to self medicate.  We cant fool around with drugs.  Metformin may not be
enough for you and you might need to add another drug.  Or you might
need a change of meds altogether.

I dont know what you are eating.  Metformin takes time to build up in
the body.

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
Alfred Kaufmann - 25 Feb 2006 22:51 GMT
>Al, every doctor has a doctor covering for him.

Yes but I have found that I need to tell them what I want.

When I first moved to this little town I asked a doctor for a
prescription which I had gotten previously in the big city.  It wasn't
until the third time that I was asked what I am using it for.

> I would not advise you
>to self medicate.  We cant fool around with drugs.  Metformin may not be
[quoted text clipped - 3 lines]
>I dont know what you are eating.  Metformin takes time to build up in
>the body.

Sometime self medicating is the smart options.  For example my doctor
put me on blood pressure medication even after I told him I have white
coat syndrome.  A month later he doubled the dosage and again I told
him I test fine at home.

I know that high blood pressure can cause stroke but what happens when
blood pressure gets too low?

Al
Susan - 25 Feb 2006 22:56 GMT
> Sometime self medicating is the smart options.  [snip]

I agree.  Unfortunately, you don't have enough information to do so
wisely.  You need to know what your post meal numbers are, most
importantly.  You also need to read up on how much CVD risk increases
with each point above 5%; your target is rather high and outdated.  You
need to know what the peaks and valleys are that are adding up to that
HbA1c.  You need to know which foods cause them and which foods keep you
in a narrower, lower range.

Susan
Vicki Beausoleil - 26 Feb 2006 02:53 GMT
>>Al, every doctor has a doctor covering for him.
>
[quoted text clipped - 21 lines]
>
> Al

Blood pressure meds (ACE inhibitors or ARBs) do more for the diabetic
than just lower blood pressure. They also protect the kidneys and heart,
by a process my endo calls 'arterial modification'. Keeps the artery
walls supple and helps prevent kidney damage.

My endo's standard for bp is 120/70 or less for a diabetic regardless of
type. She believes diabetics should be treated as if they've already had
a heart attack.

Vicki
Jenny - 24 Feb 2006 13:50 GMT
> I have been taking 2 500mg metformin tablets daily for a month now and
> according to my glucose meter my trend over that period is going up.
[quoted text clipped - 7 lines]
> reading over the next 2 weeks then I really think I should get off
> Metformin.

If you are taking Metformin ER, the max dose is 2000 per day. The higher
dose is for the plain stuff.

> If Metformin does not work for me maybe there is some other drug that
> will work for me?

Insulin. When I took metformin, I saw a mild decrease in my post meal
spikes but no change in the too-high fasting blood sugar that had
started creeping up, and it continued creeping up. On the plus side, my
weight became easy to manage, but on the minus side after a year my A1c
had not changed even by 1% at the top dose.

Turns out, that in my case, though I apparently had some mild IR which
it corrected, with it I am very insulin sensitive, but my insulin is not
able to control my blood sugar. Only by adding a basal insulin to my
regimen was I able to make a significant change in my overall blood
sugar status.

So if raising your metformin dose to 2000 mg/day does not improve
things, you need to consider whether, in fact, your problem is not
Insulin Resistance, but Insulin Deficiency.

--Jenny

http:www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
Larry - 24 Feb 2006 16:19 GMT
Jenny: I like your idea about "Insulin Deficiency". I even talked my
Doc into doing an fasting "insulin level". It came back normal.  I
heard somewhere that a "stimulated insulin level" ie. after meal is
more revealing. I propose that docs start thinking more about
subcategories of T2 patients as diabetes is a hetergeneous
disease..right ?

Larry
> > I have been taking 2 500mg metformin tablets daily for a month now and
> > according to my glucose meter my trend over that period is going up.
[quoted text clipped - 36 lines]
> http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
> Sugar Under Control
Jenny - 24 Feb 2006 17:23 GMT
> Jenny: I like your idea about "Insulin Deficiency". I even talked my
> Doc into doing an fasting "insulin level". It came back normal.  I
> heard somewhere that a "stimulated insulin level" ie. after meal is
> more revealing. I propose that docs start thinking more about
> subcategories of T2 patients as diabetes is a hetergeneous
> disease..right ?

"Insulin deficiency" is well understood by researchers who work with
type 2 diabetes. Check out John Gerich's articles on what causes type 2
diabetes.

http://scholar.google.com/scholar?q=Gerich%20Diabetes%20insulin%20deficiency

It would be wonderful if doctors thought about subcategories, but they
are very busy and if 98% of their diabetes patients appear to fit into
the obvious categories, and respond to common treatments, they don't
have the time to worry about that other 2%.

And because so much of what doctors "know" is driven by what drug
companies tell them, there has been an overemphasis on insulin
resistance being the central defect in Type 2 diabetes--because there
are some expensive patented drugs being very heavily promoted to
doctors--drugs that fight insulin resistance.

Now that we are getting the incretin hormone mimics, we'll start seeing
doctors attributing type 2 also to problems with those hormones. My
doctor has already started doing that.

But no one is putting money into educating doctors that there are all
kinds of other reasons why insulin might not be produced or if produced,
might not work properly, so doctors don't think of that until everything
else doesn't work. Except when they have a patient, like me, who demands
that they if nothing else, give me the tests and tools to figure out
what is going on.

Mostly, though, by the time a lot of doctors get to where they have an
established practice, their curiosity about what is going on in disease
and the use of treatments beyond the Drug of the Day  seems to have been
completely stamped out. <sigh>
--Jenny

http:www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
Nicky - 24 Feb 2006 22:27 GMT
> http://www.phlaunt.com/diabetes  Diabetes Info

Oo! Very smart : )  Made me go off for a re-read, thanks.

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

Jenny - 24 Feb 2006 22:40 GMT
>>http://www.phlaunt.com/diabetes  Diabetes Info
>
> Oo! Very smart : )  Made me go off for a re-read, thanks.
>
> Nicky.

Thanks! The Phlaunt.com gallery is so much easier to maintain and pretty
up than the geocities site was, and the annoying ads are gone.

But the geocities site has such good Google search placement on relevant
searches like "blood sugar targets", that I hope the move doesn't mess
that up.  The geocities site still has all it's content but people who
visit the old site get wafted to the new one  as soon as they click on
anything.

Any topics you'd like to see discussed there in future pages?

--Jenny

http:www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
Nicky - 24 Feb 2006 23:15 GMT
> Any topics you'd like to see discussed there in future pages?

Well, I think we need some info on speed of control, as soon as Chris's eye
doc comes up with something : )
Also perhaps something on all the new types, with their implications for
treatment?
A good links page, maybe? - although they're always such a pain to maintain.

> http:www.phlaunt.com/diabetes  Diabetes Info

You need to fix the link in your sig, btw.

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/74/72Kg

Alan S - 25 Feb 2006 02:16 GMT
Was Metformin Results

>>>http://www.phlaunt.com/diabetes  Diabetes Info
>>
[quoted text clipped - 14 lines]
>
>--Jenny

Hi Jenny

Looks good. I keep promoting your
http://www.geocities.com/lottadata4u/moreresearch.htm on the
ADA forum - should I be using
http://www.phlaunt.com/diabetes/14045678.php instead?

I'm still browsing through the new format - impressive.
You've done a lot of good work there. One minor point - I'm
not sure that Jennifer's asd testing advice is an FAQ, but
http://www.faqs.org/faqs/diabetes/faq/ certainly is - is
there a link to those that I missed?

For those who don't know what I'm talking about - start
here: http://www.phlaunt.com/diabetes/

Brilliant job Jenny - I keep learning from you (pity that I
can't remember it all:-)

Cheers, Alan, T2, Australia.
d&e, metformin 2x500mg
Signature

Everything in Moderation - Except Laughter.

Susan - 25 Feb 2006 02:33 GMT
> For those who don't know what I'm talking about - start
> here: http://www.phlaunt.com/diabetes/
>
> Brilliant job Jenny - I keep learning from you (pity that I
> can't remember it all:-)

I couldn't open it earlier today, but WOW, Jenny, brilliant it is.

You're an incredible asset and resource.

Susan
Jenny - 25 Feb 2006 14:43 GMT
> I couldn't open it earlier today, but WOW, Jenny, brilliant it is.
>
> You're an incredible asset and resource.
>
> Susan

Thanks!

--Jenny

http:www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
Robert Miles - 25 Feb 2006 16:33 GMT
> > I couldn't open it earlier today, but WOW, Jenny, brilliant it is.
> >
[quoted text clipped - 7 lines]
>
> http:www.phlaunt.com/diabetes  Diabetes Info

Some of us find our software works better if you make it:

http://www.phlaunt.com/diabetes
Jenny - 25 Feb 2006 17:38 GMT
Robert Miles wrote:>
>>--Jenny
>>
[quoted text clipped - 3 lines]
>
> http://www.phlaunt.com/diabetes

Thanks!  Nothing like a typo in the URL, eh? It's fixed.

Signature

--Jenny

http://www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control

Jenny - 25 Feb 2006 14:21 GMT
> Looks good. I keep promoting your
> http://www.geocities.com/lottadata4u/moreresearch.htm on the
> ADA forum - should I be using
> http://www.phlaunt.com/diabetes/14045678.php instead?

Yes. While I am maintaining the old site, because it has such good
Google placement, the new site is what I'll be updating.

It has none of those annoying ads. It's  very fast, extremely easy to
update, and it provides a lot of features for customizing the page's
visual look. I'm not visual (heck, I can barely see), but most site
visitors are, and the block-o'-print look of the old site was daunting
to a lot of people.

> I'm still browsing through the new format - impressive.
> You've done a lot of good work there. One minor point - I'm
> not sure that Jennifer's asd testing advice is an FAQ, but
> http://www.faqs.org/faqs/diabetes/faq/ certainly is - is
> there a link to those that I missed?

I guess it isn't, technically an FAQ as defined in newsgroup-speak. I'll
have to think of a better term for what it is.  OTOH, it does answer the
most important Type 2 diabetes FAQ.

> For those who don't know what I'm talking about - start
> here: http://www.phlaunt.com/diabetes/
>
> Brilliant job Jenny - I keep learning from you (pity that I
> can't remember it all:-)

I can't remember it all either, which is why it is nice to be able to
keep the information in a central place.  My memory is such that it is
only a matter of time until I'll be searching Google for my car keys. <g>

To repeat my question to Nicky, can you think of any other topics that
should be discussed there?

--Jenny

http:www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
Frank Roy - 25 Feb 2006 18:16 GMT
Hi Jenny:

> Yes. While I am maintaining the old site, because it has such good
> Google placement, the new site is what I'll be updating.

I know that Google is more sophisticated in it's placements than the old
search engines.  What are you doing to address this issue? I looked at
the page source code of your new site and your old one. You have put a
"link" html in the old page.

Frank
Jenny - 25 Feb 2006 19:14 GMT
> I know that Google is more sophisticated in it's placements than the old
> search engines.  What are you doing to address this issue? I looked at
> the page source code of your new site and your old one. You have put a
> "link" html in the old page.

All I've ever done to ensure excellent Google placement on any web site
I've built is to put up meaty pages full of content.  It takes at least
a year until anything happens, then one day the pages float up to the
top of the relevant Google searches.

I don't believe you can influence Google index placement with the kinds
of tricks that used to work on Alta Vista et. al. eight years ago
though a lot of people still make money convincing people they can do
just that.

--Jenny

http://www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
W.M.McKee - 25 Feb 2006 14:24 GMT
>Was Metformin Results
>
>>>>http://www.phlaunt.com/diabetes  Diabetes Info

Jenny, you are an amazing lady.... What a great site!

Will, T2
Larry - 24 Feb 2006 22:52 GMT
Jenny: I agree with your assessment. Thanks for the nice review article
by John Gerich.

Larry
> > Jenny: I like your idea about "Insulin Deficiency". I even talked my
> > Doc into doing an fasting "insulin level". It came back normal.  I
[quoted text clipped - 41 lines]
> http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
> Sugar Under Control
Alfred Kaufmann - 25 Feb 2006 22:58 GMT
>> I have been taking 2 500mg metformin tablets daily for a month now and
>> according to my glucose meter my trend over that period is going up.
[quoted text clipped - 29 lines]
>things, you need to consider whether, in fact, your problem is not
>Insulin Resistance, but Insulin Deficiency.

I'll  give Metformin another month or two and then I will discuss
"basal insulin" with my doctor.  Does this fall into the same category
as homeopathic insulin?

Al
Priscilla H. Ballou - 24 Feb 2006 21:19 GMT
> I have been taking 2 500mg metformin tablets daily for a month now and
> according to my glucose meter my trend over that period is going up.
[quoted text clipped - 17 lines]
> weeks and I do not want to wait that long.  I can give him the graphs
> when he gets back.

What are you eating?

Priscilla
Julie Bove - 24 Feb 2006 21:29 GMT
> I have been taking 2 500mg metformin tablets daily for a month now and
> according to my glucose meter my trend over that period is going up.
[quoted text clipped - 17 lines]
> weeks and I do not want to wait that long.  I can give him the graphs
> when he gets back.

Metformin takes several weeks to kick in.  It's not a fast acting drug.  And
once kicked in, it can take several more weeks to get the dose adjusted.
It's also possible that this drug won't work for you or that you might need
an additional drug along with it.  Just curious why you'd want to give him a
graph though.  The Drs. I've seen have wanted to see my log book.  Never a
graph.

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Susan - 24 Feb 2006 21:31 GMT
> Metformin takes several weeks to kick in.  It's not a fast acting drug.

And in my case, about 5 months!

Susan
Nicky - 24 Feb 2006 22:33 GMT
> Just curious why you'd want to give him a
> graph though.  The Drs. I've seen have wanted to see my log book.  Never a
> graph.

I'd put money on him only testing fasting. Nice and easy to graph, tells the
doc if he's progressing, but does nothing to allow him to control it
himself.

Nicky.

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A1c 10.5/5.4/<6  T2 DX 05/2004
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Alfred Kaufmann - 25 Feb 2006 23:08 GMT
>> Just curious why you'd want to give him a
>> graph though.  The Drs. I've seen have wanted to see my log book.  Never a
>> graph.
>
>I'd put money on him only testing fasting.

You would have lost that bet.  I almost never test fasting, I leave
that to the clinic.

> Nice and easy to graph, tells the
>doc if he's progressing, but does nothing to allow him to control it
>himself.

My computer reads my meter and then at the touch of a button I can get
reports and pretty graphs.  It can't get any easier.

Al
Hi_Therre - 24 Feb 2006 23:51 GMT
>> I have been taking 2 500mg metformin tablets daily for a month now and
>> according to my glucose meter my trend over that period is going up.
[quoted text clipped - 24 lines]
>graph though.  The Drs. I've seen have wanted to see my log book.  Never a
>graph.

Graphs are much easier to interpret.  Raw data is almost impossible to
correlate.
_____________________________________________
http://www.healthdiabeticsoftware.com/  Free
Alfred Kaufmann - 25 Feb 2006 23:06 GMT
>> I have been taking 2 500mg metformin tablets daily for a month now and
>> according to my glucose meter my trend over that period is going up.
[quoted text clipped - 24 lines]
>graph though.  The Drs. I've seen have wanted to see my log book.  Never a
>graph.

The graph is produced by One Touch software and is easier to see how
you are doing.  The log would be the next page. :-)

I am giving it another 8 weeks to kick in.

Al

Susan - 25 Feb 2006 23:07 GMT
> The graph is produced by One Touch software and is easier to see how
> you are doing.  The log would be the next page. :-)
[quoted text clipped - 3 lines]
> Al
>  

Al, it took 5 months for it to really kick in for me, I was very
severely insulin resistant.  When it did kick in, the results were very
obvious and sudden.

Susan
 
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