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Medical Forum / Diseases and Disorders / Diabetes / January 2006

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Evelyn Ruut - 17 Jan 2006 23:27 GMT
Hi Everybody,

I went to the Dr. today for the results of the blood test I took last week
and here are the results I said I'd report back with.

Been taking Pantethine for three months 300 mg Jarrows every night.  No
change in my cholesterol at all, not even a couple of points.  Doc is
insisting I need to go on Pravachol because he says it has less of the side
effects that made me so miserable with the other ones.

Unfortunately I guess I am not one of the lucky ones for whom this
supplement works.  I will probably keep on taking it since I have it anyway,
and perhaps it will be beneficial in some way, but the numbers did not bear
out the expectations.

I didn't get a copy of the full report on the breakdown of the cholesterol,
but he said there was no change there either.

A1-C was 6.3  :-)

Lost 5 lbs :-)

Cholesterol 259 :-(

Acetyl L. Carnitine, Coenzyme Q-10, Jarrows ALA time release, are the only
other supplements I take

Synthroid, Diovan HCL, Actos

:-(

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

wmmckee@cox.net - 17 Jan 2006 23:34 GMT
> A1-C was 6.3  :-)
>
> Lost 5 lbs :-)
>
> Cholesterol 259 :-(

Hi Evelyn,

Congratulations on two out of three! Not bad.... We just have to come up
with a strategy on that cholesterol. Have you tried red yeast rice? That was
one of the things I took that helped me knock mine down by around 55 points.
Although, I have to admit that was not the only thing I did....  You can
beat this problem, though, I do know that.

Please let us know however we can support you.

Will, T2
Susan - 17 Jan 2006 23:50 GMT
>>A1-C was 6.3  :-)
>>
[quoted text clipped - 9 lines]
> Although, I have to admit that was not the only thing I did....  You can
> beat this problem, though, I do know that.

William, red yeast rice *is* a statin.

Susan
W.M.McKee - 18 Jan 2006 03:38 GMT
>>>A1-C was 6.3  :-)

I sort of knew that, Susan, but it is cheaper...:-)

Will, T2
Loretta Eisenberg - 18 Jan 2006 00:21 GMT
Will, one of my favoriite songs,  Two out of three aint bad by meat
loaf.  love it.

loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
Cheri - 18 Jan 2006 01:01 GMT
Great singer IMO, not a bad actor either. I love his Bat out of Hell CD.

--
Cheri

Loretta Eisenberg wrote in message
<27717-43CD89FD-1487@storefull-3233.bay.webtv.net>...
Will, one of my favoriite songs,  Two out of three aint bad by meat
loaf.  love it.

loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
W.M.McKee - 18 Jan 2006 03:49 GMT
>Will, one of my favoriite songs,  Two out of three aint bad by meat
>loaf.  love it.
>
>loretta

You are singing my music, Loretta!

By the way, did you know that you have a very ancient and
distinguished name? Lauretta was one of the young ladies at the heart
of Boccacio's " Decameron". If you did not already know, I thought you
might like to.

I really like that song, by the way! I just hope Evelyn knows that and
takes heart.

Will, T2
Evelyn Ruut - 18 Jan 2006 12:00 GMT
>>Will, one of my favoriite songs,  Two out of three aint bad by meat
>>loaf.  love it.
[quoted text clipped - 12 lines]
>
> Will, T2

I am Will..... thanks to all my friends here on asd!

You guys are the greatest :-)
Signature


Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Loretta Eisenberg - 18 Jan 2006 16:25 GMT
Will, Lauretta is not Loretta.  Is that the same.  I was named after
Loretta Young but because my grandfather was named Louis

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
wmmckee@cox.net - 18 Jan 2006 17:22 GMT
> Will, Lauretta is not Loretta.  Is that the same.  I was named after
> Loretta Young but because my grandfather was named Louis

Hi, Loretta, I just happened to think of that last night... I have stray
thoughts ricocheting around in my skull all the time! It occurred to me that
"Loretta" might be a variation of the Italian Florentine name of "Lauretta",
or vice-versa, who by the way seems to represent "justice" in the way "The
Decameron" is organized, as written by Boccacio.

If you have not read The Decameron" you might try it sometime... It is
fascinating reading, bearing in mind that it comes from the peiod of about
1350, and relates to a great plague that swept Florence and all that part of
Italy. The year of the Black Death was 1348.... As the work begins, a group
of privileged young men and women flee Florence to escape the Black Death,
and travel in the surrounding countryside to different villas for a number
of days, entertaining themselves at intervals by telling stories to their
group. In all, as I recall, there are 100 stories, hence the name
"Decameron". The character, "Lauretta", was one of the young story tellers
in the party, known as the "brigata". Shakespeare and many others of
literary import are known to have taken inspiration at times from the
"Decameron".

If you already had thought of all this in relation to your name, of if you
already knew all this stuff, please feel free to discard. Sometimes, I just
get carried away on useless tangents.... On the other hand, if it is of
interest to you, or anyone else, maybe it will help someone, somewhere, to
connect the dots, as it were, and have a deeper appreciation of what has
gone before us in our civilization and our common humanity.

I hope you are having a fine day!

Will
Evelyn Ruut - 18 Jan 2006 00:35 GMT
>> A1-C was 6.3  :-)
>>
[quoted text clipped - 15 lines]
>
> Will, T2

Hi Will,

Thanks :-)

I am going to increase the amount of Pantethine and see if that and the
Pravachol in a very low dose helps.

Did you know that Red yeast rice is actually the same thing as a statin
drug?

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Alan S - 18 Jan 2006 00:50 GMT
>>> A1-C was 6.3  :-)
>>>
[quoted text clipped - 25 lines]
>Did you know that Red yeast rice is actually the same thing as a statin
>drug?

Hi Evelyn

Congrats on the results; can't help on the lipids. I tried
most of the alternatives to a statin and some supplements
but had to accept that the only thing that works for me is
lipitor. Good luck in your search.

When you said "he says it has less of the side effects that
made me so miserable with the other ones" were you referring
to all the statins or one in particular?

Cheers, Alan, T2, Australia.
Signature

Everything in Moderation - Except Laughter.

Evelyn Ruut - 18 Jan 2006 11:57 GMT
> Hi Evelyn
>
[quoted text clipped - 8 lines]
>
> Cheers, Alan, T2, Australia.

I've tried them all Alan :-(
Was on Lipitor the longest and in the strongest dosages.

The Pravachol is supposedly the newest and the one with the least side
effects.
Signature


Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

oldal4865 - 18 Jan 2006 02:21 GMT
Evelyn Ruut wrote in message ...
>. . .(snip). .
>
[quoted text clipped - 9 lines]
>
>Evelyn

    Red Yeast = Lovastatin

 I had encouraging results with 300 mg/day Pantethine.    I am currently
testing 600 mg/day.     The cites provided by Susan talked about 900 mg/day.

Regards
 Old Al
Susan - 17 Jan 2006 23:50 GMT
> Hi Everybody,
>
[quoted text clipped - 8 lines]
> Unfortunately I guess I am not one of the lucky ones for whom this
> supplement works.

Evelyn, the dose in the research that I took for excellent results was
450mg twice per day.  I don't think you gave it an adequate trial.
There's nothing to say you couldn't take even more than that, but
nothing to say that the dose you took is effective.

 I will probably keep on taking it since I have it anyway,
> and perhaps it will be beneficial in some way, but the numbers did not bear
> out the expectations.

You didn't take the well studied therapeutic dose.  :-(

I won't tell you what you should do, but I will say that there's no good
reason to believe pantethine has failed you.

I hope you'll consider trying to up the dose, it's atoxic even in end
stage renal and hepatic patients.

Susan
Evelyn Ruut - 18 Jan 2006 00:33 GMT
> x-no-archive: yes
>
[quoted text clipped - 29 lines]
>
> Susan

Susan I will "up" the dosage if it isn't toxic.

Three 300's a day maybe?  (since that is the size I have on hand already)
Hmmm... I could take two at night and one in the morning.

But meanwhile I think I need to also try the Pravachol.  He is starting me
on the 10, which I hope won't give me too much trouble.   The Lipitor was
awful stuff.   It lowered the cholesterol just fine, but I never felt worse
in my life.  He says this one has the least amount of side effects.  I will
absolutely refuse to take anything any stronger than ten even if it doesn't
get the numbers down enough.

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Susan - 18 Jan 2006 01:18 GMT
> Susan I will "up" the dosage if it isn't toxic.

It's described as a well known "atoxic" medication in at least one of
the abstracts I've posted.  No AEs even in dialysis and hepatitis
patients.  Recently, an abstract indicated that in vitro, it improves
the function of hepatocytes.

> Three 300's a day maybe?  (since that is the size I have on hand already)
> Hmmm... I could take two at night and one in the morning.

Can you split them into halves and take 450 twice per day?

> But meanwhile I think I need to also try the Pravachol.  He is starting me
> on the 10, which I hope won't give me too much trouble.   The Lipitor was
> awful stuff.   It lowered the cholesterol just fine, but I never felt worse
> in my life.  He says this one has the least amount of side effects.  I will
> absolutely refuse to take anything any stronger than ten even if it doesn't
> get the numbers down enough.

Evelyn, I wish the best for you, and if you try it, I hope you have
better luck with it.  My concern is that if you do both things at the
same time and get results, how do you decide which to stick with?

Susan
Evelyn Ruut - 18 Jan 2006 12:05 GMT
> x-no-archive: yes
>
[quoted text clipped - 4 lines]
> Recently, an abstract indicated that in vitro, it improves the function of
> hepatocytes.

That's good.

>> Three 300's a day maybe?  (since that is the size I have on hand already)
>> Hmmm... I could take two at night and one in the morning.
>
> Can you split them into halves and take 450 twice per day?

Unfortunately they are enclosed in a gel type cap.   Not splittable.  But I
don't think it would be a problem taking more, if as you say, it is really
non toxic even in very sick people.   I could go more conservatively and
just take two a day with the small dose of Pravachol.

>> But meanwhile I think I need to also try the Pravachol.  He is starting
>> me on the 10, which I hope won't give me too much trouble.   The Lipitor
[quoted text clipped - 6 lines]
> luck with it.  My concern is that if you do both things at the same time
> and get results, how do you decide which to stick with?

Susan the truth is I won't exactly know.   But I really can't wait or
continue with my cholesterol so high anymore.  He is going to check me again
in another three months.   I will continue with the pantethine anyway since
I believe there is good reason to think it is beneficial.

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Alan S - 18 Jan 2006 22:45 GMT
>  But I really can't wait or
>continue with my cholesterol so high anymore.  He is going to check me again
>in another three months.   I will continue with the pantethine anyway since
>I believe there is good reason to think it is beneficial.

You said "Cholesterol 259". That's highish, but the
breakdown is important to see what's bad and what's not
before you get too concerned. Do you know the individual
breakdown - HDL, LDL and trigs? In particular, what is the
trigs/HDL ratio?

Cheers, Alan, T2, Australia.
Signature

Everything in Moderation - Except Laughter.

Evelyn Ruut - 18 Jan 2006 23:19 GMT
>>  But I really can't wait or
>>continue with my cholesterol so high anymore.  He is going to check me
[quoted text clipped - 8 lines]
> breakdown - HDL, LDL and trigs? In particular, what is the
> trigs/HDL ratio?

He said the bad cholesterol was well over a hundred and it should be below.
I cannot remember the exact numbers.   I really should've gotten a copy.
Signature


Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Susan - 18 Jan 2006 23:34 GMT
> He said the bad cholesterol was well over a hundred and it should be below.
> I cannot remember the exact numbers.   I really should've gotten a copy.

Mine was well over 100 (126) and my doctor was thrilled because my
ratios were good and my VLDL was low.

You need more information, Evelyn.

Susan
Evelyn Ruut - 19 Jan 2006 03:32 GMT
> x-no-archive: yes
>
[quoted text clipped - 8 lines]
>
> Susan

Yes, I can see that.   Of course most of the time I think I should trust the
professional, but as Jenny pointed out, most of what the professionals know
comes from drug salesmen.   Sucks, doesn't it?

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Jefferson - 19 Jan 2006 19:30 GMT
Hi Susan and Evelyn:

>> Been taking Pantethine for three months 300 mg Jarrows every night.  
>> No change in my cholesterol at all, not even a couple of points.  Doc
[quoted text clipped - 21 lines]
> I hope you'll consider trying to up the dose, it's atoxic even in end
> stage renal and hepatic patients.

I know that Susan has posted numerous references to pantethine in the
past.  I did a scholar.google.com search using pantothenic+cholesterol+
human+dose and came up with 533 finds - http://tinyurl.com/boo88.

I also know of a person that doses at Pantothenate (B5), 7.6 gm/day and
has done so for some time. He is a big man - about 6' 6" tall and 207
pounds (2.04m height, 94kg weight).  If he had a problem with toxicity
using pantothenate it would have cropped up already.  I am not
suggesting this man's dosage, but just citing it as a case in point of
an extreme dose.

Evelyn: I notice in another post in this thread that you take CoQ10.

"CoQ10—A Brief Review
Food sources of CoQ10 include beef heart, sardines, anchovies,mackerel,
salmon, broccoli, spinach, and nuts. Although CoQ10 can be obtained from
these foods (only about 3-5 mg per day), it would require consuming
large quantities to be the equivalent of taking a CoQ10 supplement.
CoQ10 is biosynthesized from tyrosine through a cascade of aromatic
precursors, which indispensably require certain vitamins: vitamins B2,
B6, B12, folic acid, niacin, pantothenic acid, and vitamin C. CoQ10
functions as a carrier to transfer electrons across the membrane of
mitochondria (the energy generator in the body’s cells) to drive the
production of adenosine triphosphate (ATP), the fuel that energizes
cells in our body. Heart muscle cells have the greatest concentration of
mitochondria—5,000 per cell. Prior to supplementation, the basal plasma
CoQ10 concentration in healthy individuals has been reported in
various studies to range from 0.3 µg/ml to 1.0 µg/ml. A decrease in
the levels of coenzyme Q10 in our bodies is associated with aging and
as a result of certain medications, such as statin drugs."

Frank
Cheri - 17 Jan 2006 23:57 GMT
Congratulations on the weight loss Evelyn. :-)

--
Cheri

Evelyn Ruut wrote in message ...
>Hi Everybody,
>
[quoted text clipped - 33 lines]
>Evelyn
>(to reply to me personally, remove 'sox')
Evelyn Ruut - 18 Jan 2006 00:34 GMT
> Congratulations on the weight loss Evelyn. :-)
>
> --
> Cheri

Thanks so much Cheri :-)
Signature


Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Grandpa Chuck - 18 Jan 2006 00:43 GMT
Congratulations on those first two numbers.
We strive for progress, not perfection.

>Hi Everybody,
>
[quoted text clipped - 26 lines]
>
>:-(

Signature

Grandpa Chuck
-ô¿ô-
 ~

The following information is given with the utmost respect
for the armed forces and civilians who have died in the
current war in Iraq. According to http://icasualties.org/oif/
The number of Americans killed in Iraq as of Jan. 16, 2006 is 2,220.
United Kingdom = 98 Other = 103  Iraqi deaths in excess of 30,000
according to President Bush - probably many more.

Chief - 18 Jan 2006 02:30 GMT
> Hi Everybody,
>
[quoted text clipped - 26 lines]
>
>:-(

Great going. Since this ugly old head of mine cointains no helpful
knowledge I'll contribute a laugh.

I tried begging out of my wife's office party Christmas and she
graciously relented.

I asked her how she had put up with me all these years.

She said because I reminded her of Cary Grant.

I said, "How so dear, is it my good looks, silver sideburns and smooth
moves?"

She replied, "No dear, I loved you both so much when ya'll were alive."

Needless to say, we went to the party.
Evelyn Ruut - 18 Jan 2006 11:59 GMT
>> Hi Everybody,
>>
[quoted text clipped - 43 lines]
>
> Needless to say, we went to the party.

LOL!  That was a cute one!

:-)

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

W.M.McKee - 18 Jan 2006 13:15 GMT
>Hi Everybody,
>
[quoted text clipped - 26 lines]
>
>:-(

Hi Evelyn,

Sorry I did not realize about your issue with Statins and the
connection with red yeast rice as one of the things that would make
you have bad side effects. I guess I was not thinking, or in a brain
fog, when I mentioned I had tried red yeast rice. I certainly did not
mean to be so thoughtless.

We will just have to find a way without statins, or anything like
them, that's all...

I hope you have a great day.

Will, T2
Evelyn Ruut - 18 Jan 2006 13:58 GMT
>>Hi Everybody,
>>
[quoted text clipped - 45 lines]
>
> Will, T2

Hi Will, no apology necessary :-)   I am increasing the pantethine and
taking the lowest dose of Pravachol available.  Hopefully it will improve
things by next time around.

We are having lots of high winds and heavy rain today.   Hope it doesn't
knock down any trees like the last storm did!

Have a great day too!

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

wmmckee@cox.net - 18 Jan 2006 16:26 GMT
> We are having lots of high winds and heavy rain today.   Hope it doesn't
> knock down any trees like the last storm did!

Hi Evelyn,

Yes, we are having very high winds and rain here, too... Right now, they
seem to have died down a little, but they are still blowing at about 33 mph.
I was awakened at 4:00 A.M. this morning by the storm.

Hope you can manage to have a good, in spite of the storm.

Will, T2
Nicky - 18 Jan 2006 13:22 GMT
> A1-C was 6.3  :-)
>
> Lost 5 lbs :-)

Nice going : )

> Cholesterol 259 :-(

What was the breakdown last time? Total chol really doesn't tell you much...
if you can, ask him for the full panel (including whether LDL was measured
or calculated), you might be seeing something of a swing just from that
weight loss.

Nicky.

Signature

A1c 10.5/5.4/<6  T2 DX 05/2004
1g Metformin, 100ug Thyroxine
95/73/72Kg

Evelyn Ruut - 18 Jan 2006 21:41 GMT
>> A1-C was 6.3  :-)
>>
[quoted text clipped - 10 lines]
>
> Nicky.

The numbers were exactly the same as last time, good and bad cholesterol.
I didn't get a copy, but he did tell me what they were.   Again, same as
last September.

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

up2trouble - 18 Jan 2006 20:07 GMT
I also had problems with those cholesterol meds.  I'm not taking
anything now because the dr wants to try getting my weight down first.
A while back I was taking something I got from my Chiropractor balled
Cholarest.  It didn't help my bad cholestrol but the good doubled.
Maybe you'll do better than I did.
Evelyn Ruut - 18 Jan 2006 21:40 GMT
>I also had problems with those cholesterol meds.  I'm not taking
> anything now because the dr wants to try getting my weight down first.
> A while back I was taking something I got from my Chiropractor balled
> Cholarest.  It didn't help my bad cholestrol but the good doubled.
> Maybe you'll do better than I did.

Thanks for the advice.

Last night I took the damned Pravachol, and all day today my legs ached.
First time in months!
Signature


Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Susan - 18 Jan 2006 21:54 GMT
> Last night I took the damned Pravachol, and all day today my legs ached.
> First time in months!

Evelyn, the rx info for those drugs says to stop taking it immediately
if you experience aches from it.

Susan
Evelyn Ruut - 18 Jan 2006 23:18 GMT
> x-no-archive: yes
>
[quoted text clipped - 5 lines]
>
> Susan

I stop taking them and the doctor throws a fit, telling me that I am in a
very high risk group for heart attack.   I am going to try it for a week and
if it continues I will stop it again.   It could've been coincidental, but I
don't know......

I have a friend who is a doctors wife.   Believe me she gets the best care.
Anyway she has the same problem and she's on the Pravachol too.  :-(

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Susan - 18 Jan 2006 23:33 GMT
> I stop taking them and the doctor throws a fit, telling me that I am in a
> very high risk group for heart attack.

Is it possible that he hasn't read the prescribing information?  Even
the TV commercials say to STOP if you develop body aches!  My mother's
doc told her to ignore them, too, and she ended up debilitated and on
steroids for a year to recover.  She didn't even have a bad lipid
profile or any hx of CVD.  Her only geriatric illness was caused by statins.

  > I am going to try it for a week and
> if it continues I will stop it again.   It could've been coincidental, but I
> don't know......
>
> I have a friend who is a doctors wife.   Believe me she gets the best care.
> Anyway she has the same problem and she's on the Pravachol too.  :-(

We'll agree to disagree about what constitutes "best care."  :-/

Susan
Evelyn Ruut - 19 Jan 2006 03:29 GMT
> x-no-archive: yes
>
[quoted text clipped - 18 lines]
>
> Susan

But I don't really disagree, Susan.  I hate the stuff.  I feel like I am
taking poison every time I go on them, and the doctor pushes me to go back
on.   Last time I said "screw it" and never took them at all and had the
best few months ever.   I got the new blood test and the party was over.   I
am going to take more pantethine but am still very conflicted about the
statin.

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

Susan - 19 Jan 2006 15:28 GMT
> But I don't really disagree, Susan.  I hate the stuff.  I feel like I am
> taking poison every time I go on them, and the doctor pushes me to go back
> on.   Last time I said "screw it" and never took them at all and had the
> best few months ever.   I got the new blood test and the party was over.   I
> am going to take more pantethine but am still very conflicted about the
> statin.

Here's the deal, Evelyn.  The research on pantethine says it inhibits
HMG-CoA, same as statins.  It also says it has an anti-inflammatory
effect (inhibits thrombaxane A2), same as statins.  The biggest diff is
that it has no known toxic level or adverse reaction reports, even at
doses way higher than you are taking and in end stage renal and
hepatitis patients.

You haven't given it a real trial, and you seem more afraid of possible
CVD than you are of clearly evident statin damage occurring in your
case.  Those consistent and reproducible muscle aches you get on statins
mean you, like my mother, probably can't take any of them.

You can increase the pantethine, try the Zetia that Jenny recommended,
but you should think long and hard about the risks of a drug that gives
you a very clear warning every time you take it.

BTW, when I looked up HMG-CoA inhibition, I found that ascorbic acid,
garlic, vitamin E, certain pre and probiotics, and berries and cherries
all inhibit it, too.  Add the anti-inflammatory effects of olive oil and
it explains a lot about the benefits of certain Med diets, I think.

Susan
Jenny - 18 Jan 2006 23:37 GMT
> I stop taking them and the doctor throws a fit, telling me that I am in a
> very high risk group for heart attack.   I am going to try it for a week and
> if it continues I will stop it again.   It could've been coincidental, but I
> don't know......

Your doctor has "benefited" from hundreds of hours of "education" from
the people who sell these drugs which has convinced him and his peers
that his patients will all die without them.

Here are the facts. Muscle pain suggests that the drug is causing muscle
breakdown.  Left unchecked it can be fatal. Even worse, the heart, too,
is a muscle. If the drug is causing muscle breakdown in the heart, you
could be on your way to heart failure.

Doctors ignore known drug side effects all the time. They don't read the
prescribing information and get all their information about the drugs
from the pretty girls who the drug companies send out as salespeople.

Go read the complete prescribing information from Pravacol. This is the
information that the FDA insists the drug company must publish about the
drug. Any warning in it must be taken seriously.

Here's the prescribing information:
http://www.bms.com/cgi-bin/anybin.pl?sql=select%20PPI%20from%20TB_PRODUCT_PPI%20
where%20PPI_SEQ=56&key=PPI


Here's an excerpt:
Skeletal Muscle
Rare cases of rhabdomyolysis with acute renal failure secondary to
myoglobinuria have been reported with pravastatin and other drugs in
this class. Uncomplicated myalgia [muscle pain] has also been reported
in pravastatin-treated patients (see ADVERSE REACTIONS).
Myopathy, defined as muscle aching or muscle weakness in conjunction
with increases in creatine phosphokinase (CPK) values to greater than 10
times the upper limit of normal, was rare (<0.1%) in pravastatin
clinical trials. Myopathy should be considered in any patient with
diffuse myalgias, muscle tenderness or weakness, and/or marked elevation
of CPK. Patients should be advised to report promptly unexplained muscle
pain, tenderness or weakness, particularly if accompanied by malaise or
fever. Pravastatin therapy should be discontinued if markedly elevated
CPK levels occur or myopathy is diagnosed or suspected.

HAS YOUR DOCTOR DONE THE LIVER TESTS THAT THE PRESCRIBING INFORMATION
SAYS SHOULD BE DONE BEFORE PRESCRIBING THIS DRUG?  HAS HE TESTED CPK?

If not, they you might want to challenge him as to why he's ignoring the
guidelines the drug company has publicly stated for the use of this drug.

--Jenny

http://www.geocities.com/lottadata4u  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
Evelyn Ruut - 19 Jan 2006 03:33 GMT
Thanks Jenny.
This is important food for thought.
I saved your post and will continue studying.
You know I hate statins.   They make me feel like hell.

Signature

Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

>> I stop taking them and the doctor throws a fit, telling me that I am in a
>> very high risk group for heart attack.   I am going to try it for a week
[quoted text clipped - 49 lines]
> http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
> Sugar Under Control
Jenny - 19 Jan 2006 14:51 GMT
> Thanks Jenny.
> This is important food for thought.
> I saved your post and will continue studying.
> You know I hate statins.   They make me feel like hell.

Evelyn,

My endocrinologist told me quite a few of her older women patients have
had trouble with statins.  She put me on a non-statin drug which lowered
my cholesterol a lot. It was Zetia.

Why not ask your doctor if you can try the Zetia instead?

I had to stop the Zetia, because it worked TOO well for me. At "normal"
levels my body was acting as if it was completely deprived of the
cholesterol it needed to support vision and the manufacture of estrogen.
But that is probably because I have that genetic thing where my LDL
cholesterol molecules are huge and thus test very high when they are
actually at healthy levels.

--Jenny

http://www.geocities.com/lottadata4u  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
Evelyn Ruut - 19 Jan 2006 20:27 GMT
Jenny I tried Zetia and it gave me diarrhea.
Signature


Best Regards,

Evelyn
(to reply to me personally, remove 'sox')

>> Thanks Jenny.
>> This is important food for thought.
[quoted text clipped - 22 lines]
> http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
> Sugar Under Control
Jenny - 20 Jan 2006 14:56 GMT
> Jenny I tried Zetia and it gave me diarrhea.

So sorry to hear that. I hope you can find some solution that works for
you.

--Jenny

http://www.geocities.com/lottadata4u  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
noneyabusiness - 22 Jan 2006 20:33 GMT
>Hi Everybody,
>
[quoted text clipped - 26 lines]
>
>:-(

I had good luck (over a 2 month period) using Pantethine, plant
sterols, and niacin.

I took 2 300mg caps of the Pantethine, 2 500mg tabs of niacin, and 4
tabs of the plant sterols (half in the AM, the rest at night).

Just be careful with the niacin as it may bite you if you don't take
it with food ;-)

Also, none of this helped my HDL :(
The Doc said the best thing was a good workout.
I said I'd work on it <g>.

...
Susan - 22 Jan 2006 21:23 GMT
> I had good luck (over a 2 month period) using Pantethine, plant
> sterols, and niacin.
[quoted text clipped - 10 lines]
>
> ...

You may get better HDL results by raising the pantethine to 450 mg,
twice per day, the dose that's been studied and found effective.

My HDL went up to an all time high of 70 on it.

Susan
 
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