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Medical Forum / Diseases and Disorders / Diabetes / January 2006

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Almost OT:  Urinalisis and Ketones

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acoftil - 10 Jan 2006 22:26 GMT
Hello group-

I'm back for a bit.  :)

Last Friday I came down with a raging UTI.  Actually, it was four days after I'd
finished anti-biotics for a UTI, so it had come back worse than ever.

Some of the lab results confuse me.  I"ve been to many sites that explain lab
results, but none can help me be specific to my situation, as there are no
standard reference ranges.  (according to the material I've read today)

The reason I'm asking here, is it is the Ketone results that perplex me.

I am in the best control I could dream of.  My numbers are all in the "normal"
ranges now.  My normal FBG is 99.  :)  I've come very far since diagnosed in
2-2004.

The results read:  Component:  Ketones, UA
                               Value (result):  50mg%
                                Flag:  A (meaning abnormal)
                                 Range:  Negative (or none)

I did not find that an infection could cause ketones in the urine.  The only
thing I could come up with to explain this is that I hadn't eaten in quite a
while--mainly because the infection came on so fast, I had to just go to the
doctor.  

Is the % sign a typo?  What does it mean?

Other findings, just in case it is useful:

Hemoglobin, UR, QL, PH, UA; LARGE (Abnormal)  (reference is NEGATIVE)
Protein, UA: 100 mg% (Abnormal) (reference is NEGATiVE)
Leukocyte Esterase, UA:  LARGE (Abnormal) (reference is NEGATIVE)

Here's the good part.  ;)

WBC, Urine:  Value:  25-50, Flag: (abnormal) (reference 0-5/HPF)
RBC, Urine:  Value >100, Flag (abnormal) (reference 0-5/HPF)

Yes, it is a really bad infection.  I'm taking Cipro for 10 days, not the usual
7 days.

Thanks for any insight anyone has.
TIA,
Nancy :)
Jenny - 10 Jan 2006 23:10 GMT
> Hello group-
>
[quoted text clipped - 42 lines]
> TIA,
> Nancy :)

Nancy,

If you are eating a low carb diet--as defined as under 100 grams of
carbohydrate a day, you may have ketones in your urine. As long as this
occurs along with normal blood sugars, this is usually not a problem.

When your blood sugar is high, like, say, over 300 mg/dl and you have
ketones in your urine, there is a  problem.

Not eating for a while could conceivably put you into a fasting state,
and that too will generate ketones.

I'm not sure what the % means, but the lab tests consider any ketones
abnormal, because they assume everyone is eating their 300 grams of carb
a day.

--Jenny

http://www.geocities.com/lottadata4u  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
bj - 11 Jan 2006 01:36 GMT
> If you are eating a low carb diet--as defined as under 100 grams of
> carbohydrate a day, you may have ketones in your urine. As long as this
[quoted text clipped - 3 lines]
> abnormal, because they assume everyone is eating their 300 grams of carb a
> day.

There's a *lot* of territory between 100 & 300 grams!
bj
Ma¢k - 11 Jan 2006 04:16 GMT
>> Hello group-
>>
[quoted text clipped - 60 lines]
>
>--Jenny

Jenny is partially correct.  she is wrong in thinking that ketones
only with a high BG of say 300+ is dangerous.  A type 1, not sure
about a type 2, can easily go into full blown dangerous DKA with a
near normal BG and an infection.

However you are not describing any signs of DKA.  you should go back
to your doc and tell him/her that you want that 50mg% explained to
you.  And if the doc doesn't know that you want the doc to look it up
and get back to you with the correct answer.

one thing you could do is to check you ketones with the ketodiastix
from any pharmacy.  They are not expensive.  Trace amounts of ketones,
especially in a low carb diet are nothing to worry about.  moderate to
high readings need to be looked into by your doc.

Signature

Mâck©®
Type 1 since 1975
http://www.alt-support-diabetes.org
http://www.diabetic-talk.org
http://www.insulin-pumpers.org

"To announce that there must be no criticism of the
President, or that we are to stand by the President
right or wrong, is not only unpatriotic and servile,
but is morally treasonable to the American public."
...Theodore Roosevelt

        (o o)  
--ooO-(_)-Ooo--------------------

"I don't know half of you
half as well as I should like;
and I like less than half of you
half as well as you deserve."

Jesus never hated anyone.

acoftil - 11 Jan 2006 17:37 GMT
>However you are not describing any signs of DKA.  you should go back
>to your doc and tell him/her that you want that 50mg% explained to
>you.  And if the doc doesn't know that you want the doc to look it up
>and get back to you with the correct answer.

I intend to.  I'm just too busy this week.  I have a new doctor and so far he is
wonderful!  When I whined about something fairly normal for a 50 yr old woman,
he said, Oh, you are still 25, see your chart!  LOL  He's a sweetheart.  I can
email my doctor questions like this.  If he doesn't know the answer, I can call
the lab directly.  

>one thing you could do is to check you ketones with the ketodiastix
>from any pharmacy.  They are not expensive.  Trace amounts of ketones,
>especially in a low carb diet are nothing to worry about.  moderate to
>high readings need to be looked into by your doc.

Chit!  And I have the strips sitting on a shelf above the toilet.  I just have
to use them!  What is the best time of day for this?  Morning?

Thank you Mack and everyone.  I knew this was the place to ask such a question.
:)
Nancy :)
Ma¢k - 11 Jan 2006 21:45 GMT
>>However you are not describing any signs of DKA.  you should go back
>>to your doc and tell him/her that you want that 50mg% explained to
[quoted text clipped - 18 lines]
>:)
>Nancy :)

any time of the day.  for a fairly accurate reading I was told to void
my bladder, then drink some water and test the next time I could go.
This way you are not getting readings based on what's been sitting in
your bladder until the urge to urinate hits you.

Signature

Mâck©®
Type 1 since 1975
http://www.alt-support-diabetes.org
http://www.diabetic-talk.org
http://www.insulin-pumpers.org

"To announce that there must be no criticism of the
President, or that we are to stand by the President
right or wrong, is not only unpatriotic and servile,
but is morally treasonable to the American public."
...Theodore Roosevelt

        (o o)  
--ooO-(_)-Ooo--------------------

"I don't know half of you
half as well as I should like;
and I like less than half of you
half as well as you deserve."

Jesus never hated anyone.

acoftil - 17 Jan 2006 20:05 GMT
>any time of the day.  for a fairly accurate reading I was told to void
>my bladder, then drink some water and test the next time I could go.
>This way you are not getting readings based on what's been sitting in
>your bladder until the urge to urinate hits you.

Thanks for the tip.  I just took the last anti-biotic today.  So, I'll test
tomorrow, to ensure I'm cured!  :)
Nancy :)
acoftil - 11 Jan 2006 17:34 GMT
>If you are eating a low carb diet--as defined as under 100 grams of
>carbohydrate a day, you may have ketones in your urine. As long as this
[quoted text clipped - 5 lines]
>Not eating for a while could conceivably put you into a fasting state,
>and that too will generate ketones.

I should have mentioned that I'm not on a low carbohydrate diet.  Until the
Holidays I avoided simple carbohydrates, but did not count my carbs.  I've eaten
way too many carbohydrates over the Holidays, but that is getting back to normal
now.  :)

I believe I'm only eating about 1,000 calories/day right now--which is up from
825 a year ago this time.  So, slowly but surely I'm gaining a bit back and
eating a bit more.  :)

I'm also a pre-diabetic for now.  

I suspect the readings are from a lack of eating and a raging infection.

Thank you so much,
Nancy :)
J.C. Hartmann - 10 Jan 2006 23:28 GMT
> Hello group-
>
[quoted text clipped - 42 lines]
> TIA,
> Nancy :)

The term "mg%" is just another way of saying mg/dL, the same way we
measure BG. It is a % weight/volume measure, pronounced "milligram percent".

Leukocyte Esterase is a test for an enzyme that indicates leukocytes
(white blood cells) in the urine. This is a definitive test for a UTI
when there is no indication of elevated WBCs in the urine. Of course,
you have both WBCs and RBCs in your urine. You also have blood (from the
hemoglobin test) and are spilling protein in your urine, meaning that
the filters which normally prevent protein from escaping in urine are
inflammed and leaking protein.

Ketones are a byproduct of catabolizing fat in the Kreb's Cycle. The
most likely cause is that you hadn't eaten enough carbs in the recent
past, and your body had switched to burning fat. This should not be a
problem for a Type-2.

Everything points to a nasty UTI. Drinking lots of fluids should help,
and once you get rid of the infection, your BG and other important
diabetic measurements should return to normal.

Jim
acoftil - 11 Jan 2006 17:53 GMT
>> Hello group-
>>
[quoted text clipped - 45 lines]
>The term "mg%" is just another way of saying mg/dL, the same way we
>measure BG. It is a % weight/volume measure, pronounced "milligram percent".

AH!  That's easy to understand.  :)

>Leukocyte Esterase is a test for an enzyme that indicates leukocytes
>(white blood cells) in the urine. This is a definitive test for a UTI
[quoted text clipped - 3 lines]
>the filters which normally prevent protein from escaping in urine are
>inflammed and leaking protein.

What a mess and it all happened within one hour!  Hopefully the Cipro will clear
it all up.  :)

>Ketones are a byproduct of catabolizing fat in the Kreb's Cycle. The
>most likely cause is that you hadn't eaten enough carbs in the recent
>past, and your body had switched to burning fat. This should not be a
>problem for a Type-2.

I stopped gathering information about Ketones, because I'm type 2 and it
appeared it didn't apply to me.  But, I bought the strips, because to me
diabetes is a science experiment, so why not test everything possible.  ;)

What you say explains one other thing.  One theory of Fibromyalgia is that we
have a broken Kreb's Cycle.  This is why I started taking alpha lipoic acid long
before I ever had a clue I was pre-diabetic.  I don't have much fat to burn
these days.  My weight concern is loosing too much, not gaining weight.  

In any case, if Ketones aren't being processed properly, it could affect my
Fibromyalgia by making me even more sore and can put me into a flare.  I'm in a
flare right now.  Icky.

If you are reading, what do Julie Bove and Evelyn think about this?

The people with diabetes on AMF (fibro group) do not seem to be open to this
type of discussion, or maybe they just don't have enough information to discuss
it?

Another note:  I've been taking the time released form of alpha lipoic acid for
the last year.  I do believe that it is lowering my bg numbers.  At least it is
helping with my control.  I did not start taking the time released form for this
reason, so I'm fairly certain this is an accurate conclusion.

>Everything points to a nasty UTI. Drinking lots of fluids should help,
>and once you get rid of the infection, your BG and other important
>diabetic measurements should return to normal.

Yup.  I'll do some testing starting tomorrow.  I find it pointless for ME to
test under the current circumstances.  It just gets me all worked up.

I think there is a live spring under my couch!  LOL  I can't believe how much
I'm drinking.  And I'm taking cranberry pills, rather than the juice.

I'm going shopping with Mom today--she gave me a shopping spree for Christmas
and today is pay off.  :D  I'm going to drive her nuts going potty all the time.
<eg>

Nancy :)
Gary - 11 Jan 2006 01:50 GMT
To prevent further UTI's use Cranberry extract.  It's well known to
help prevent them.
It's cheap, natural, and has no bad side effects.
73  Gary
Ozgirl - 11 Jan 2006 10:45 GMT
> To prevent further UTI's use Cranberry extract.  It's well known to
> help prevent them.
> It's cheap, natural, and has no bad side effects.

And drink lots of water, pee straight after sex, wipe from
front to back after using the toilet (for women) and don't
have bubble baths... UTI's are so easy to catch and so easy
to prevent (most of the time). It used to be called
Honeymoon cystitis - i.e. women often get them when they
have just got married (or these days after more sex than
usual etc). A doctor told me all this advice more than 35
years ago and I have never forgotten it ;) I strongly urge
anyone who thinks they have one, to start straight away on
lots of water with urinary alkaliser (can get them from the
pharmacy in sachets - keep them ready) and go the same day
to the doc for antibiotics. Kidney infection is not the best
way to go after an ignored "bladder" infection. In other
words, don't treat one at home. A persistent one may need to
be tested further to get the exact bacteria type.
acoftil - 11 Jan 2006 18:04 GMT
>And drink lots of water, pee straight after sex, wipe from
>front to back after using the toilet (for women) and don't
[quoted text clipped - 11 lines]
>words, don't treat one at home. A persistent one may need to
>be tested further to get the exact bacteria type.

Hi Ozgirl!  You haven't said anything I didn't know, but it's been a very long
time and I appreciate the reminders.  :)

I think the sex thing may be part of the problem.  But, the fix makes sex not as
fun.  :(

Actually, I had just finished a course of sulfa (3 days) for a UTI.  About 4
days later (last Friday), it came back.  I felt fine, almost totally well.  I
took a shower and had that urge that you can't ignore.  I peed out straight
bright red blood with clots.  ACK!  I called the doc's office at 1 PM and I was
seen by 1:50 PM.  My HMO is very good when the problem is this urgent.

I was pretty lucky, the infection had not spread to my kidneys.  :)  But, my
experience just demonstrates that Ozgirl is right on.  At the least hint of a
UTI, call the doctor.  I did not wait even one minute and I still had a nasty
infection raging.
Nancy :)
acoftil - 11 Jan 2006 17:58 GMT
>To prevent further UTI's use Cranberry extract.  It's well known to
>help prevent them.
>It's cheap, natural, and has no bad side effects.
>73  Gary

I do take cranberry pills.  I don't remember being recommended the extract.  I
respect the advice of my local health food store--so I just did what they
advised.  I'll go back and ask them which would be best for me.  :)

The UTI thing is new to me.  I've had 4 in the last year (3 mild) and none for
almost 20 years prior.  There are a number of things that might have led to this
one.  It's just a matter of figuring details out.

UTI's are not my biggest problem right now.  There were findings on my lung
x-rays and that is what I want to pursue right now.  The scary thing is that the
apparently more serious finding has nothing to do with smoking at all.  We think
we know what caused it (building fires and scooping cat litter), but have not
done a formal investigation yet.  In the meantime, DH scoops and I use a mask to
tend fire.

Thanks for the advice.  I'll check out the extract.
Nancy :)
 
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