My Dr put me on the Metformin XR yesterday. The prescription states 2
metformin tabs per day. Does that mean I take both tablets at once or twice
a day like I did the regular metformin? They should have said horse pills:)

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jacquie
I don't suffer from insanity....
I enjoy every minute of it!
Loretta Eisenberg - 02 Nov 2005 18:16 GMT
Jacquie, two metformin XR, at one time after dinner is what I believe.
I take three at one time after dinner.
Loretta
--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
pverburgh - 02 Nov 2005 18:28 GMT
Jacquie, when I was put on the Metformin, I was told to take one in the
morning with breakfast and then one at supper time. What you should do is
call and ask your doctor about it as he/she will be able to explain it to
you.
Jeannette
> My Dr put me on the Metformin XR yesterday. The prescription states 2
> metformin tabs per day. Does that mean I take both tablets at once or
> twice a day like I did the regular metformin? They should have said horse
> pills:)
Terry Stone - 02 Nov 2005 18:45 GMT
I was told two a day of the XR - one in the morning and one at
night. Check with the doctor and see what he/she prescribed.
Terry
> My Dr put me on the Metformin XR yesterday. The prescription states 2
> metformin tabs per day. Does that mean I take both tablets at once or twice
> a day like I did the regular metformin? They should have said horse pills:)
BJ in Texas - 02 Nov 2005 19:31 GMT
|| My Dr put me on the Metformin XR yesterday. The prescription
|| states 2 metformin tabs per day. Does that mean I take both
[quoted text clipped - 4 lines]
|| I don't suffer from insanity....
|| I enjoy every minute of it!
Nobody here is qualified to answer your question, we can only
tell you what our experience is. For medical advise, call your
doctor, he is qualified, that is what you pay him for.
BJ

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"A pessimist is correct oftener than an optimist, but an
optimist has more fun." -- Robert A. Heinlein - Time Enough For
Love
Jenny - 02 Nov 2005 21:18 GMT
> My Dr put me on the Metformin XR yesterday. The prescription states 2
> metformin tabs per day. Does that mean I take both tablets at once or twice
> a day like I did the regular metformin? They should have said horse pills:)
By all means, call up the doctor or the pharmacist and ask them what the
dosing schedule should be.
HOWEVER, metformin can cause intense gastric upset in some people, so
many people find it best to start out with one Metformin, take it for a
few days until the side effects calm down and only then add the second
one. Taking the two tabs together the first time might be more than your
body can handle.
I felt poisoned the first week I took Metformin and it was very
worrying. But it passed, and I started feeling fine and losing weight
without dieting while my post-meal blood sugars dropped to much more
reasonable levels. That was enough to make me a fan for life
--Jenny
http://www.geocities.com/lottadata4u/ Type 2 Diabetes info
http://www.geocities.com/jenny_the_bean/ Low Carb info
Priscilla H. Ballou - 02 Nov 2005 21:21 GMT
> My Dr put me on the Metformin XR yesterday. The prescription states 2
> metformin tabs per day. Does that mean I take both tablets at once or twice
> a day like I did the regular metformin? They should have said horse pills:)
I have taken mine at the same time and also split them up. My
understanding is that the timing of this med is adjusted to avoid GI
side-effects and doesn't affect the efficacy of the drug. I've noticed
no difference in my response between the times when I took the doses
together and the times when I split them up. Your clinician is the one
to check with for the definitive instructions for how you should take
the med.
Priscilla
pverburgh - 02 Nov 2005 21:50 GMT
I looked at my prescription bottle and mine is Co-Metformin. Suppose to be
better than the other one I was taking. The taste of the pill is what I was
told.
Jeannette
> My Dr put me on the Metformin XR yesterday. The prescription states 2
> metformin tabs per day. Does that mean I take both tablets at once or
> twice a day like I did the regular metformin? They should have said horse
> pills:)
Larry - 04 Nov 2005 03:03 GMT
Never heard of Co-Metformin.. Is it a combo with Avandia by chance??
larry
pverburgh - 07 Nov 2005 15:51 GMT
I am just taking the Co-Metformin. I am not taking the Avandia.
Jeannette
> Never heard of Co-Metformin.. Is it a combo with Avandia by chance??
>
> larry
W. Baker - 03 Nov 2005 00:22 GMT
: My Dr put me on the Metformin XR yesterday. The prescription states 2
: metformin tabs per day. Does that mean I take both tablets at once or twice
: a day like I did the regular metformin? They should have said horse pills:)
: I don't suffer from insanity....
: I enjoy every minute of it!
I don't know wht your doctor wants, but I take 1000mgs in the AM and
1000mgs in the PM, breakfast an dinner, and all XR. It works for me,
keeping me free of the trots most of the time unless i eat some sugar
alcohols!
Wendy
jacquie - 04 Nov 2005 00:53 GMT
Thanks Guys, I called the Dr's office today and they said take two at once.
The info sheet suggest it is taken with the evening meal....:)
RB - 08 Nov 2005 03:09 GMT
>Thanks Guys, I called the Dr's office today and they said take two at once.
>The info sheet suggest it is taken with the evening meal....:)
You received the correct info from your doctor.
For extended release metformin the prescribing info says to take at
one time.
For regular metformin split doses are recommended.
http://www.rxlist.com/cgi/generic/metformi_ids.htm
or the PDR if you have access.
RB
Jenny - 08 Nov 2005 15:14 GMT
> For extended release metformin the prescribing info says to take at
> one time.
>
> For regular metformin split doses are recommended.
>
> http://www.rxlist.com/cgi/generic/metformi_ids.htm
RB,
Despite what it says in the prescribing information, I have found that
for me there is a slight difference in the effect of the ER when the
dose is split. Despite claims of it reaching a steady state, there seems
to be some peaking.
Bernstein says on P. 229 of "Dr. Bernstein's Diabetes Solution" that
the timed release Metformin seems to have a peak 7 hours after you take
it. I have noticed slightly lower morning blood sugars if I split my
dose and take a dose at night. Unfortunately, I have also noticed that
it seems to make me pee more, which makes me wake up more, which rules
out a night dose as a useful strategy.
The other thing about Metformin ER is that different companies' versions
may vary in potency. When my pharmacy changed manufacturers and gave me
a different shaped pill of the same dosage, I developed gastric symptoms
for a few days just like what I get if I boost my dosage. Other people
have reported similar things.
What I have found over the years about Prescribing Information is that
the data is based on statistical findings drawn from group studies done
with people with very high blood sugars. Sometimes individual variations
in metabolism or maintaining a much lower blood sugar than the average
will cause a person to experience different results than what the PI
states.
--Jenny
http://www.geocities.com/lottadata4u/ Type 2 Diabetes info
http://www.geocities.com/jenny_the_bean/ Low Carb info
Larry - 08 Nov 2005 15:59 GMT
Hi Jenny: I'm thinking of switching to the BMS product (glucophage)
rather than the metformin generic I'm taking now. Recently I changed
from metformin ER (PAR Co.) to regular metformin with no change in
dose. I thought I was seeing a real change in FBG down to 110 range.
This lasted only a week and then back up to the 140+ range again. It
was a real but transitory effect. It seems the body kicks in
compensitory mechanisms to keep the status quo.
Larry
> > For extended release metformin the prescribing info says to take at
> > one time.
[quoted text clipped - 34 lines]
> http://www.geocities.com/lottadata4u/ Type 2 Diabetes info
> http://www.geocities.com/jenny_the_bean/ Low Carb info
jacquie - 08 Nov 2005 18:23 GMT
I don't seem to have problems taking it in the evenings...I will keep an eye
on my afternoon numbers to see if there is a problem. One reason I wanted to
go to ER was because I had a hard time remembering to take that second
pill....plus the regular Metformin made me really nauseous...the other
gastro stuff went away after the first few months of taking it. I am so far
having no gastro problems with the ER(knock on Wood) I am in my 50's so get
up in the middle of the night to pee anyways, and have seen no change. Now
when I take my lasix in the morning that is another story : )

Signature
jacquie
I don't suffer from insanity....
I enjoy every minute of it!
Jenny - 09 Nov 2005 00:06 GMT
I am in my 50's so get
> up in the middle of the night to pee anyways, and have seen no change. Now
> when I take my lasix in the morning that is another story : )
Jacquie,
I took all 3 Metformin ER tabs together at once for a long time and it
worked fine for me. I have the same problem with not remembering them if
they get split up. The getting up at night problem is worse for me than
most people as I have a damaged bladder which can react to medications
pretty strongly. Most people probably wouldn't experience that
difference. As it is, I already wake up 2 times every night. The third
time is killer. . .

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--Jenny
http://www.geocities.com/lottadata4u/ Type 2 Diabetes info
http://www.geocities.com/jenny_the_bean/ Low Carb info
jacquie - 09 Nov 2005 23:59 GMT
Before I had my adrenal gland removed I was up all night...it seemed when I
was in the prone position my adrenal would shoot out some hormone that made
me pee more. Sorry about your bladder problem...I had to have bladder repair
in my 30's it wasn't fun. I like taking the Metformin at one time...and so
far am not having any side effects at all...now if they could just make them
a little bit smaller...LOL..:)

Signature
jacquie
I don't suffer from insanity....
I enjoy every minute of it!
> I am in my 50's so get
>> up in the middle of the night to pee anyways, and have seen no change.
[quoted text clipped - 9 lines]
> As it is, I already wake up 2 times every night. The third time is killer.
> . .