Has anyone ever had a reaction to metformin? Two days ago I started taking
1000mg Metformins 2x per day. Last night I felt as if I couldn't breathe
and had a severe pressure in my chest. I also take 35u of NovoLog
injections 2x daily and percocets and motrin for pain. Last night I
eventually vomited and felt better almost immediately. Anyone else
experience this?
Thanks
Cuz - 26 Oct 2005 14:23 GMT
|| Has anyone ever had a reaction to metformin? Two days ago I
|| started taking 1000mg Metformins 2x per day. Last night I
[quoted text clipped - 5 lines]
||
|| Thanks
I've experienced it, but not due to Metformin.
Ozgirl - 26 Oct 2005 14:33 GMT
> Has anyone ever had a reaction to metformin? Two days ago I started
> taking 1000mg Metformins 2x per day. Last night I felt as
if I
> couldn't breathe and had a severe pressure in my chest. I
also take
> 35u of NovoLog injections 2x daily and percocets and
motrin for pain.
> Last night I eventually vomited and felt better almost
immediately.
> Anyone else experience this?
Hi waitingmore. People will jump in soon with any
experiences they may have had with metformin but in the mean
time...
I have never taken metformin but I do know it is a med that
should be started at lower doses and ramped up over time. I
am not sure by your post whether the first time you took
metformin was 2 days ago or whether two days ago was the
time you took the higher doses.
Second, regardless of a new med or not I wouldn't have let
those severe symptoms go unchecked. They could be totally
unrelated to the med and quite possibly a heart attack.
Let's hope the pressure was from gastric disturbance. But
lactic acidosis is a big concern also:
This is a condition that can be a side effect of metformin
and often rears it's head after a dose ramp-up and more
likely to occur in someone with underlying kidney or liver
problems. Kidney problems are a possibility with diabetics,
especially if they have been running high numbers for a
while. Symptoms are: nausea, vomiting, abdominal pain, lack
of appetite, feeling really "off", weakness and difficulty
breathing. It is a serious side effect and it is recommended
going off the drug immediately and reporting to your doctor.
So, sounds like a talk with the doc pretty soon is in order.
Good luck, let us know.
Uncle Enrico - 26 Oct 2005 14:44 GMT
> Has anyone ever had a reaction to metformin? Two days ago I started taking
> 1000mg Metformins 2x per day. Last night I felt as if I couldn't breathe
[quoted text clipped - 4 lines]
>
> Thanks
Symptoms of chest pressure and difficulty breating warrant an emergency
room visit. Get in to see your doctor pronto. This could be a simple
gastric disturbance which new users of Metformin experience. And I agree
with Ozgirl that this dose is too big for a starter dose. I was started
with one 500 mg dose a day. But we're not doctors!!!! Go see yours. Your
ticker is too important.
Jenny - 26 Oct 2005 16:44 GMT
> Has anyone ever had a reaction to metformin? Two days ago I started taking
> 1000mg Metformins 2x per day. Last night I felt as if I couldn't breathe
[quoted text clipped - 4 lines]
>
> Thanks
Metformin can cause a chest pain that can be very scary. My doc told me
that. However, you are taking MUCH too much. You need to start at a
lower dose and work up.
My doctor had me try the max dose last month and I ended up with the
same kind of symptom you experienced despite years of taking 1500 mg a
day with no problem at all. I almost ended up in the emergency room as
I couldn't breath and was having sharp left sided pains.
But because you are new to this, you should contact your doc and see
what he says. The symptoms of heart attack and Met overdose are too
similar for comfort.

Signature
--Jenny
http://www.geocities.com/lottadata4u/ Type 2 Diabetes info
http://www.geocities.com/jenny_the_bean/ Low Carb info
Donna Evleth - 27 Oct 2005 14:31 GMT
> From: Jenny <lottadatacarbs@hotmail.com>
> Reply-To: lottadatacarbs@hotmail.com
[quoted text clipped - 14 lines]
> that. However, you are taking MUCH too much. You need to start at a
> lower dose and work up.
I started with half the dosage you are on. I did not have chest pains, but
I had acute chronic diarrhea, flatulence that was so bad it woke me up at
night, weakness and dizziness. I am a thin diabetic, and I lost two and a
half kilos in three weeks, which I could ill afford. I gave the stuff up.
It just wasn't right for me.
I don't know why my GP prescribed it for me, as he knew I had delicate
intestines because I am coeliac, and my BGs were not really bad enough to
warrant it in the first place. He didn't want me to test - "you're not
there yet," he said - but he wanted me to take this stuff that made me so
ill. I now have a different GP, who agrees with the endocrinologist that I
saw after the metformin debacle: I don't have to take any medication right
now. Just test faithfully, exercise and watch my diet.
Donna Evleth
>
> http://www.geocities.com/lottadata4u/ Type 2 Diabetes info
> http://www.geocities.com/jenny_the_bean/ Low Carb info
Uncle Enrico - 27 Oct 2005 15:34 GMT
> I started with half the dosage you are on. I did not have chest pains, but
> I had acute chronic diarrhea, flatulence that was so bad it woke me up at
[quoted text clipped - 11 lines]
>
> Donna Evleth
I've been taking Metformin for years, but after losing 45 pounds,
through exercise and diet, and consistently getting good A1C's, 5.3 time
after time, I'm thinking of maintaining my insulin regimen but cutting
back on Metformin to see what will happen. I've already reduced the
dosage from 2000 mg a day to 1500 with no adverse effects. I'm curious
to see if I can do with less, say 1000 mg, or eliminate it entirely.
I don't recommend anyone else do this, but I would love to reduce the
drug load on my body.
Andrew B. Chung, MD/PhD - 30 Oct 2005 20:59 GMT
> Has anyone ever had a reaction to metformin? Two days ago I started taking
> 1000mg Metformins 2x per day. Last night I felt as if I couldn't breathe
> and had a severe pressure in my chest. I also take 35u of NovoLog
> injections 2x daily and percocets and motrin for pain. Last night I
> eventually vomited and felt better almost immediately. Anyone else
> experience this?
Would suggest you notify your doctor(s) ASAP. Would be concerned about
drug-induced lactic acidosis.
> Thanks
You are welcome.
All praises belong to God, Whom I love with all my heart, soul, mind,
and strength :-)
In Christ's love and service forevermore,
Andrew
--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
**
Suggested Reading:
(1) http://makeashorterlink.com/?G1D5217EA
(2) http://makeashorterlink.com/?W13A4250B
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
Alan S - 31 Oct 2005 00:42 GMT
>Would suggest you notify your doctor(s) ASAP.
The problem with a kook like chung is that when he says
something valid, it may be ignored. In this case he's
correct.
See your doctor ASAP.
Cheers, Alan, T2, Australia.

Signature
Everything in Moderation - Except Laughter.
Andrew B. Chung, MD/PhD - 31 Oct 2005 02:15 GMT
> >Would suggest you notify your doctor(s) ASAP.
>
> The problem with a kook like chung is that when he says
> something valid, it may be ignored.
The problem here resides in those who choose to judge others as kooks.
Matthew 7 comes to mind.
To redirect this thread back on-topic:
ASD participants who have type 2 diabetes and are overweight can lose
weight safely and permanently thereby possibly achieving a cure by using
the diabetic 2PD-OMER Approach as described here:
http://www.HeartMDPhD.com/wtloss.asp
Would be more than happy to chat about this and other things that
interest you here:
http://tinyurl.com/cpayh
For those who are put off by the signature, my advance apologies for how
the Lord has reshaped me:
http://tinyurl.com/bgfqt
In Christ's love and service forevermore,
Andrew

Signature
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
**
Suggested Reading:
(1) http://makeashorterlink.com/?G1D5217EA
(2) http://makeashorterlink.com/?W13A4250B
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
autoclaveman2000@yahoo.com - 31 Oct 2005 02:31 GMT
I have taken Metformin er for several years now and have found it works
a little faster then Glucophage xr. I am one of the lucky ones and
have had very little problems with this med.
If you experience chest pains and gastric pains with a new med, stop
taking it and get to the ER. This could be a cardiac reaction to the
meds.
Ira
T2
Metformin er 750mg twice a day
Glipizide 2.5 once a day
Diag. Dec. 2000
Loretta Eisenberg - 30 Oct 2005 23:28 GMT
Waiting I have never experienced a reaction as you describe. Perhaps is
completely unrelated or maybe it is related. I think you should talk to
your doctor.
Loretta
--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.