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Medical Forum / Diseases and Disorders / Diabetes / October 2005

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Effect of therapeutic steroids on BG

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Ofsted - 24 Oct 2005 22:16 GMT
Can anyone advise what sort of BG readings I should
expect with a daily dose of 30mg prednisolone for
polymyalgia rheumatica?  Am on it for 5 days.

Any input appreciated.

David

T2 Sept04  gliclazide40mg Hbca1 5.4 also lisiprol, atenolol and amlodipine
oldal4865 - 25 Oct 2005 03:04 GMT
Ofsted wrote in message ...
>Can anyone advise what sort of BG readings I should
>expect with a daily dose of 30mg prednisolone for
[quoted text clipped - 5 lines]
>
>T2 Sept04  gliclazide40mg Hbca1 5.4 also lisiprol, atenolol and amlodipine

  Type 2 diabetes is a disease marked by abnormally high Insulin Resistance
in most folks,  and a substantial amount of dead beta cells.
The effect of prednisolone will depend on how high your Insulin Resistance
actually is,  and how many live beta cells you actually have left.    That's
a balance which is almost impossible to predict.

The prednisolone will induce your liver to start manufacturing glucose and
releasing it into your blood.  That means your bG can skyrocket even though
you don't eat any carbs at all.  How high it will go and how many carbs can
you eat are questions you answer by trial and error.  You might have enough
beta cells left to handle the prednisolone or your sugars may go through the
roof.   If your bG goes too high,  you will need insulin injections to
control it.

BTW,  the better docs are now saying that the first med for a T2 ought to be
metformin.   It protects beta cells,  offers protection against the very
high tendency for T2 to suffer premature heart attack,  and,  btw, helps
with blood sugar.

Regards
 Old Al
Andrew B. Chung, MD/PhD - 25 Oct 2005 12:19 GMT
> Can anyone advise what sort of BG readings I should
> expect with a daily dose of 30mg prednisolone for
> polymyalgia rheumatica?  Am on it for 5 days.

This will vary depending on your level of insulin resistance and
pancreatic sufficiency (and medications).

> Any input appreciated.

You are welcome, David :-)

I personally invite you and all other ASD participants to an on-line
chat where one of the topics covered will be diabetes:

http://www.OurMableton.net/ParadiseChat

Hope to see you in Paradise this Thursday from 6-7 pm EST :-)


In Christ's love and service now and forevermore,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
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Ofsted - 25 Oct 2005 12:31 GMT
Thanks -

rose to 7.9  before meal
was back at 5.5 this am FBG

Will persevere and cut back hard on carbs.
When will the prednisolone effect tail off
after the five days of treatment?

David

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David A. Green
Weston s Mare
BS23 3EB
UK

www.davidagreen.com
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common sense not guaranteed

>>
>> Can anyone advise what sort of BG readings I should
[quoted text clipped - 32 lines]
> (6) http://makeashorterlink.com/?I24E5151A
> (7) http://makeashorterlink.com/?I22222129 
Dennis Rekuta - 27 Oct 2005 05:02 GMT
> Thanks -
>
[quoted text clipped - 6 lines]
>
> David

Are you only taking the 30 mg daily for 5 days? The chances are that it
will subside in a week, at most two weeks. That is a very short time and
allows for no tapering. Just watch for any jitters or mood swings the
first couple of days after stopping. Some people are more sensitive than
others. Just test often and adjust accordingly.

Dennis (Type 2)
Ofsted - 29 Oct 2005 17:50 GMT
Thanks for that Dennis
such practical advice is so helpful

I started taking PRED on Monday last (30mg) and
had the last dose of five yesterday.

My morning readings of 5.whatever stay around that
figure and then inexplicably rise at about 5pm despite having
eaten nothing.   This happened again today when I have had
had no Pred.   It is somewhat reassuring to note that it can
take a week or two. I find it so hard to account for the
late afternoon rise.   (There are times when I wish I had
no meter - I know that sounds irrresponsible) will continue
to test and am presently on the lowest carbs ever. I note
what you say about mood swings!!  I'm not entirely sure
what adjustments I can make with my carb intake so low.
Although exercise is now more feasible - it isn't so easy
with the residual aches and pains.

The last time I had this treatment they tailed it off gradually
and it took a very long time.

Once again thank you for your help.

David

>> Thanks -
>>
[quoted text clipped - 14 lines]
>
> Dennis (Type 2)
 
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