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Medical Forum / Diseases and Disorders / Diabetes / October 2005

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Newly diagnosed, have a question...

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Mo - 22 Oct 2005 05:40 GMT
Hi.  My name is Laurie, and I am newly diagnosed with type 2 diabetes.  I am
51 years old.  I am now on Prandin and Avandamet, plus insulin at night,
trying to get the BG under control.  I live in Louisiana, and my family all
live in the Greater New Orleans area, and have all suffered terrible losses
due to the recent hurricanes Katrina and Rita, so I have been under real
stress, which I am told is not good for this condition.  I also have
Fibromyalgia, and struggle daily with sleep issues.

My question is now that I am on all this new stuff, I am ALWAYS starving.  I
mean belly gnawing hungry!  What's up with that, does anyone know?  What can
I do to stop it?  I just lost 45 pounds, and don't want to gain it back.

Thanks in advance for any help,
Laurie
Patti - 22 Oct 2005 06:25 GMT
Hi Laurie,

I had that gnawing hunger too when I was first dx'd, and my doctor told
me that extreme hunger happens when your blood sugar is high. I found
that once I got mine under control, the extreme knawing hunger went
away.

You might need to talk to your doctor about medication adjustments.

Good luck.

Patti

Dx 01-2002/T2/Lantus & Humalog
pinecone - 22 Oct 2005 09:24 GMT
Hi, Laurie.

Sorry to see you here, if you know I mean!

I find that if my glucose is very high, I get very hungry, sometimes
overwhelmingly fatigued, and I also have aches and pains (especially my
head and feet!).  When my sugar is in control all of these are
diminished or even disappear.  I hope you also reach a point where this
occurs.

Please keep us posted on how the meds work for you and the side effects
over time.  Some of us get cycled through meds over time, and I like to
know what to expect.

pc
oldal4865 - 22 Oct 2005 14:38 GMT
>Hi.  My name is Laurie, and I am newly diagnosed with type 2 diabetes.  I am
>51 years old.  I am now on Prandin and Avandamet, plus insulin at night,
[quoted text clipped - 10 lines]
>Thanks in advance for any help,
>Laurie

  Newly-diagnosed diabetics often suffer from a condition called "Glucose
Toxicity" caused by extended exposure to high blood sugars before diagnosis.
Glucose Toxicity further messes up your already messed up glucose metabolism
and makes it very, very, difficult to regain control over your blood sugars.
Since the only way to "cure" Glucose Toxicity is to gain control over your
sugars and stay there for a while,   Early Days can be quite difficult for a
newly-diagnosed diabetic.

Some docs just let their patients "flounder",  some docs hit the Glucose
Toxicity with high doses of temporary meds.   Looks like your doc is one of
the latter kinds  (I'll vote for his approach)     That also means you are
subjecting your body to high doses of insulin in order to knock out the
Toxicity.    High doses of insulin  (you are taking insulin shots and
Prandin which forces your pancreas to churn out extra insulin) can make you
crave food,  especially carbohydrate.

You should be aware of your blood sugars throughout the day,  especially at
2 hours after eating.   When you normalize   (below 140 after eating,  below
110 upon awakening),   time to start talking to the doc about dropping some
of the insulin augmentation.    If you start seeing low sugars during the
day. . .. 70 or lower. . .it's really time to talk to the doc.

Many of the better docs would consider Prandin as the first candidate to
drop.

It would be useful if you could measure your blood sugars at those times of
intense craving.    If they are high  (above 140),   your doc should also
know about that.   You can knock those down with a fast insulin before
eating.    If they're low,  it's back to "cutting meds".

Of course that means that you have to test your blood sugar a lot.    That's
the way Early Days goes.    You need a lot of information about your
particular version of our disease really fast  so you have to test a lot.

For an idea of what other docs do in this case,  here's what happened to one
of our posters.  Gary's doc threw about every type of med available at him,
then started cutting the meds when he normalized.    (FWIW,  your Prandin is
similar to Glyburide,  your Avandamet is a mix of Avandia and metformin)

"From: Gary Pewitt
Newsgroups: alt.support.diabetes
Date: Tuesday, February 25, 2003 11:46 PM

>. . .My doctor caught my diabetes on the first visit and had me in
> the hospital the same day for multiple tests including x-ray
[quoted text clipped - 3 lines]
> glyburide by half four times, discontinued the Avandia (due to
> swollen legs) and started me on Glucophage [metformin]. . ."

Good luck and keep coming back.    This is an odd disease in which the
patient does all the work and most of the management.   The more you learn
about the disease and the faster you learn about it,  the better your
chances of a long and pain-free life.   Reading these diabetes newsgroups
every night has resulted in significant improvements in my health,   the
quality of my life,  and,  I'm certain,  my life expectancy.

Regards
 Old Al
autoclaveman2000@yahoo.com - 22 Oct 2005 22:05 GMT
I agree with Old Al, ".    This is an odd disease in which the patient
does all the work and most ofthen management.   The more you learn
about the disease and the faster you learn about it,  the better your
chances of a long and pain-free life."

I call diabetes an individual desease. What works for you may not work
for others Visa/versa.
The main issues are medication, diet, and exercise. Those three work
together for control.
My moto is "Diabetes does not control me but I control diabetes.

Ira Jamison
T2
Diag. Dec. 2000
Metformin (glucophage) 750mg twice a day
Glipizide 2.5mg once a day
pinecone - 23 Oct 2005 08:50 GMT
Ira,

Do you have any specific side effects from combining glipizide with
metformin?  I'm certain I'll have to go back on meds eventually--I
notice when I'm sick, no diet or exercise controls my sugar.

have to eat like a military strategist to keep my sugar in control,
and it's not as low as it was when I was on the LAF237 study (where I
took either metformin and placebo or metformin and LAF237--and they
won't tell us which until the entire study ends).

Interestingly, ibuprofen seems to wreak havoc with my sugar--but not
Tylenol.  

pc
autoclaveman2000@yahoo.com - 23 Oct 2005 10:11 GMT
Hi PC,  The only side effect I had with the combination was 20 lb
weight loss. But that was only temporary :-(

Glipizide helps the Metformin.  I was going hypo a lot with Metformin
(it is not supose to do that) When the Dr. perscribed the Glipizide I
became more in control.

With the Metformin the only side effect I have is flatuance (layman
terms the FARTS)  I tell my grandkids I have old peoples disease.Hee
Hee.

I hate taking pills so I sure watch my food intake and exercise.  

Ira
None Given - 23 Oct 2005 02:03 GMT
> My question is now that I am on all this new stuff, I am ALWAYS starving.  I
> mean belly gnawing hungry!  What's up with that, does anyone know?  What can
> I do to stop it?  I just lost 45 pounds, and don't want to gain it back.

I was always hungry until I threw away that diet they gave me.
http://www.alt-support-diabetes.org/Newly%20Diagnosed.htm

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No Husband Has Ever Been Shot While Doing The Dishes

Andrew B. Chung, MD/PhD - 23 Oct 2005 18:30 GMT
> Hi.  My name is Laurie, and I am newly diagnosed with type 2 diabetes.  I am
> 51 years old.  I am now on Prandin and Avandamet, plus insulin at night,
[quoted text clipped - 6 lines]
> My question is now that I am on all this new stuff, I am ALWAYS starving.  I
> mean belly gnawing hungry!

As long as you feeling hungry, you are NOT starving.

> What's up with that, does anyone know?

The healthier you become, the hungrier you will be.

>  What can I do to stop it?

By eating ore.

>  I just lost 45 pounds, and don't want to gain it back.

Then you will have to choose to befriend your healthy appetite (aka
hunger).

> Thanks in advance for any help

You are welcome, Laurie.

In Christ's love and service forevermore,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
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