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Medical Forum / Diseases and Disorders / Diabetes / October 2005

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Getting Paleolithic levels of Vit C in a modern diet

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Quentin Grady - 22 Oct 2005 01:47 GMT
G'day G'day Folks,

We have had Spring rains here making it a good day to crunch a few
numbers and see if we can get Paleolithic levels of Vit C on a modern
T2 friendly diet.

Basic assumptions.   The Paleolithic diet provided 600 mg of Vit C in
a 3000 kcal/day diet.  A 2000 kcal/day diet is probably more
appropriate for many of us.

The Paleolithic diet was thought to comprise 35% animal products and
65% vegetable products by weight. As a rough approximation I'll aim at
getting half the daily calories from vegetables and fruit.  

This gives me a calorie limit of 1000 kcal.
My Vit C target is 400 to 600 mg.

Sweet peppers,  1 large             312 mg   44 kcal
Broccoli,       1 cup cooked        101 mg   55 kcal
Strawberries    1 cup, whole         94 mg   46 kcal  
Snow peas       1 cup,boiled         76 mg   67 kcal    
Brussel sprouts 1 cup                70 mg   56 kcal
Asparagus       1 cup                43 mg   40 kcal

Totals                              696 mg  308 kcal

Comment:-
A bit of over run is cool since most items are seasonal.
This is a typical Spring/Summer selection.  

There is still 700 kcal unspent to allow for having to substitute
vegetables with lower Vit C content.

A Winter Paleolithic menu would be harder.

Surprising to many people, sweet peppers and broccoli out perform most
fruit. While fruit is often advocated by nutritionists for T2
diabetics it is wise to remember sweet peppers are fruit and IMHO make
a more sensible choice for many people.

One kiwi fruit                       96 mg    61 kcal  
Tangerine, manderin orange, medium   26 mg    45 kcal

BTW.  The RDA, is currently about 60 to 80 mg.
Someone can no doubt find an official figure.

Best wishes,

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Quentin Grady - 22 Oct 2005 05:36 GMT
G'day G'day Folks,

Since this is a diabetic support group I have extended the chart to
include two other items of interest, available carb and magnesium.

                                                Available
                                  VitC   Energy   Carb    Magnesium
                                  (mg)   (kcal)  (grams)     (mg)
Sweet peppers,  1 large             312     44       7         20
Broccoli,       1 cup cooked        101     55       6         33
Strawberries    1 cup, whole         94     46       8         19
Snow peas       1 cup,boiled         76     67       7         42
Brussel sprouts 1 cup                70     56       7         31
Asparagus       1 cup                43     40       4         26

Totals                              696    308       39       171
Average                             116     51        7        29

Comment.  

Vit C content varies so much the average is meaningless.  
The other averages have less variation.

As a rough rule for these T2 friendly vegetables.
 
Energy = 50 kcal  carb = 7 grams and magnesium = 30 mg

Note.  
The glycemic load for vegetables is often quoted as half the grams of
available carb. Available carb is simply total carb less fibre.

Even followers of ultra low carb sticking to 30 grams of carb per day
can easily reach 400 mg of Vit C per day. Its not the path I choose to
follow but the data shows it is easy to do if you like sweet peppers
and broccoli.

Chalk up another big plus for sweet peppers. I took my figures for red
sweet peppers since orange peppers are not listed.  The big plus for
orange peppers is that the orange is zeaxanthin that protects the most
sensitive regions of the eyes from ultraviolet, violet and blue light
damage.

Someone might want to hack out a more complete list for "free"
vegetables.

Best wishes,

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

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Chris J. - 24 Oct 2005 04:50 GMT
>G'day G'day Folks,

Greetings, Quentin.

Thank you for your excellent post. I have long been a fan of peppers
of all kinds, and eat them daily. What I had not known about was how
high Broccoli is in C. I'd been considering a supplement due to my
post-Dx drastic reduction in fruit intake, but I now see I don't need
it.
Thanks!
Quentin Grady - 24 Oct 2005 05:24 GMT
This post not CC'd by email
On Sun, 23 Oct 2005 20:50:31 -0700, Chris J. <chris@noadress.com>
wrote:

>>G'day G'day Folks,
>
[quoted text clipped - 6 lines]
>it.
>Thanks!

G'day G'day Chris,

Glad you liked it.  It can be a bit of chore preparing the tables.

 Vit C is something I haven't looked at much in the past. Vit C is a
water soluble antioxidant, whilst Vit E is fat soluble.  To form an
antioxidant network where Vit C can recycle Vit E intermediaries are
required.  The most obvious are the polyphenols.  Put simply, less
antioxidants vitamins are required when the polyphenols are present
since recycling occurs so I wasn't concerned about getting enough.  

What people don't often realise is that vitamin supplements typically
provide the antioxidant vitamins abeit in the wrong stereoisomers
forms but omit the polyphenols to get the whole thing working
coherently.  

As far as I can see there are three major reasons why food is a better
source than supplements.

A.  The vitamins are the correct stereoisomers.

B.  Food comes with intermediaries that allow the vitamins to function
properly together.

C.  The unexpected risks associated with excessive doses appear
diminished. This may be because food sources are less prone to
suppressing the functioning of closely related compounds.  For example
a food that contains alpha and beta carotene is unlikely to the
suppress the action of alpha carotene whereas a supplement containing
beta carotene without alpha carotene is more likely to do so.

Best wishes,

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Annette - 24 Oct 2005 17:53 GMT
> This post not CC'd by email
>  On Sun, 23 Oct 2005 20:50:31 -0700, Chris J. <chris@noadress.com>
[quoted text clipped - 6 lines]
> antioxidants vitamins are required when the polyphenols are present
> since recycling occurs so I wasn't concerned about getting enough.

Hi there Quentin,

I have always known, even if intuitively, that fresh ordinary foods just had
to be the best way to obtain all the necessary items needed to promote good
health. I mean, it's simply logical, after all, the human race evolved
without supplements!  Less helpful though, was knowing just which foods were
more nutritious and health-promoting, especially given the metabolic
disorder we call T2 diabetes. We have to make choices based on availabilty
and cost, let alone the limited capacity of just how much we can eat in one
day!

You initiated my interest in seeking to find out all I could about just what
is in our food, what it did for us, and so on. I'm still struggling to
understand a lot of the info I've collected!

BUT, I had not come across the term polyphenols, or more likely, had not
noticed that particular name for this subset of micronutrients.

So I went Googling, and found out a lot of interesting things, and not only
about polyphenols.

For those other than yourself, who would also like to learn a little more
about this fascinating area of nutrition that is less commonly discussed by
dieticians, here are some of the major sites I found. Do feel free to
correct any errors I may have made in writing this.

For those who just want something fairly easy to read and follow;
http://www.ars.usda.gov/Aboutus/docs.htm?docid=4142
Phytonutrient FAQs

For those who want something a bit more scientific and more in detail,
including a very nice little chart;
http://encyclopedias.families.com/bioactive-food-components-201-205-efc
Bioactive food components.

Finally, for the really clever people who like to really get into scientific
studies, here is an abstract about current studies on polyphenols in
particular. Since I did not wish to pay for the full article, I did not go
any further with this one;
http://www.ajcn.org/cgi/content/abstract/79/5/727
Polyphenols: food sources and bioavailability1,2

Anyway, here's a small idea of what this is all about, for the majority of
folk who simply want a bit of and idea on what to eat.

1. Phytonutrients, which include the polyphenols, are found naturally in all
ordinary fresh foods. You'll notice that they are also called MICRO
nutrients. That's because they are such a small part of what we eat, yet are
extremely important in maintaining good health, or even healing us of damage
done to our bodies.

MACRO-nutrients are the Big 3 stuff, like protiens, fats and carbohydrates,
that provide the energy all living things need. We need lots and lots of
that stuff, but it simply is not enough by itself to keep the complicated
system (our metabolism) working smoothly.
Actually, one of the items included in these studies that *does* come in
large, obvious amounts, is fiber. It just looks kind of useless, seeing as
it contributes nothing (or very little) to our daily energy needs. So it
doesn't make the Big 3. But it is still very important for a number less
obvious metabolic reasons.
Somewhere in the middle are the vitamins and minerals we have come to know
and love in modern times.

2. Most studies concentrate on the ones from the vegetable kingdom, since
there are so many of them. In short, fruit and vegetables are wonderful
sources of these very important yet comparitively minor parts of our food.

3. Polyphenols are also known as flavinoids or similar, with those funny
names you often see Quentin writing about in this group. Like lutein,
quercetin, hesperidin, zeaxanthin, or that real tongue twister, astaxanthin,
one of the ones that comes from sea animals like salmon or prawns. There's a
zillion of them, many that appear to do nothing, and heaps that are not
understood at all, one way or the other.

So eat lots of veges and some fruit, and anything else you see Quentin
recommending as being important.  It probably is!
If at all possible, always try to meet your nutritional needs from natural
food sources. It the best way to ensure you get a balanced amount, and have
included things you need, including those that even the scientists still
don't know about.
Variety is not only more interesting, but gives you a larger range of
possibilities, as well.

Annette
Munching her way through life!
Jefferson - 24 Oct 2005 20:14 GMT
> Finally, for the really clever people who like to really get into scientific
> studies, here is an abstract about current studies on polyphenols in
> particular. Since I did not wish to pay for the full article, I did not go
> any further with this one;
> http://www.ajcn.org/cgi/content/abstract/79/5/727
> Polyphenols: food sources and bioavailability1,2

The full article is accessible for free and has some articles citing it
that maybe of interest. ;)
http://www.ajcn.org/cgi/content/full/79/5/727

Frank Roy
Jefferson, Maryland
Annette - 25 Oct 2005 14:30 GMT
> > Finally, for the really clever people who like to really get into scientific
> > studies, here is an abstract about current studies on polyphenols in
[quoted text clipped - 9 lines]
> Frank Roy
> Jefferson, Maryland

Thank you so much, Frank!

I admit to having you in mind when I referred to the abstract. I just knew
you'd know how to find the whole article!

Now all I have to do is find time to read and try to follow all the
information in there. Still, I guess it keeps me off the streets!

As I learn more and more about the wonders to be discovered in living
organisms and their systems, it always fills me with awe at the complex
intricacy of it all. As a great line in the classic TV show "MASH" says:
"The glory of it all!"

Life is truly a divine dance.

Annette
Quentin Grady - 24 Oct 2005 21:16 GMT
This post not CC'd by email
On Mon, 24 Oct 2005 16:53:48 GMT, "Annette" <acianthus@bigpond.com>
wrote:

>Hi there Quentin,
>
>I have always known, even if intuitively, that fresh ordinary foods just had
>to be the best way to obtain all the necessary items needed to promote good
>health. I mean, it's simply logical, after all, the human race evolved
>without supplements!

G'day G'day Annette,

 Sure did ... well almost.  Many civilizations added spices which
often turn out to be pretty power supplements.  Cloves for instance
have a huge antioxidant capacity.  That said, such "supplementing" is
too recent to have played much part in natural selection.

Have _we_ evolved to fit cosily into the beneficent cradle of
evolution?  That is a more disturbing question.  Basically I view
myself and other T2 diabetics as damaged goods.  Our metabolic
pathways don't all behave in the carefully fashioned manner laid down
by evolution.  Put simply, we MIGHT need some supplementation.  While
research has firmly established that non-diabetic Australians can
convert alpha linolenic acid, a slightly shorter chain omega-3 into
the longer chain EPA and DHA with reasonable efficiency after a couple
of weeks the situation with T2 diabetics is more problematic.  We
might need supplementing with fish oil.

[snip]

>1. Phytonutrients, which include the polyphenols, are found naturally in all
>ordinary fresh foods. You'll notice that they are also called MICRO
[quoted text clipped - 13 lines]
>Somewhere in the middle are the vitamins and minerals we have come to know
>and love in modern times.

Your comments here got me thinking.  Are polyphenols present in small
amounts than vitamins?  IMHO polyphenols are more like vitamins who
missed out on the titles.  To take a simple example think of
betacarotene.  It exists naturally in two forms, cis beta-carotene and
trans-betacarotene.  Only the trans form converts to Vit A.  The cis
form is a very useful antioxidant.  People typically regard Vit A as a
vitamin and include beta-carotene, its precursor as also being a
vitamin.  What of its close cousins, lutein and zeaxanthin?  Do they
deserve vitamin status?   Are they "essential" to life as is required
in some definitions of vitamins?  Well seeing is pretty essential and
the retina in eyes don't function without lutein and zeaxanthin.  Even
hens have evolved to acknowledge this simple fact of life.  Of the
thousands of bioflavonoids they have in their diet the two they insist
on passing on to their offspring, if they get the chance, are lutein
and zeaxanthin.  Some like beta-cryptoxanthin may well cut the risk of
arthritis and cervical cancer but is this essential?  Essential tends
to defined in rather cruel terms ... surviving to produce offspring.

>2. Most studies concentrate on the ones from the vegetable kingdom, since
>there are so many of them. In short, fruit and vegetables are wonderful
>sources of these very important yet comparitively minor parts of our food.

Polyphenols are typically present in equal or LARGER amounts that
vitamins.
               Polyphenols     Vit C  
Apples            187            7  
Apricot            66            8
Apricot,dried     307            1
Avocado           148            8
Banana            120           10
Blackcurrant     1150          160
Blueberry         740           12
Boysenberry       630            9
Cherry            178           15
Date              317            0
Grapefruit         46           37
Kiwifruit         108           97
Melon              23           33
Orange             39           52
Peach              112           9
Raisin             400           3
Raspberry          300          19    
Strawberry         159          51
Watermelon          12           8

Large variation in composition of some antioxidants depending on
colour (in most cases the stronger the colour the higher the
antioxidants) Although they do not always have strong overall
antioxidant activity, these fruits are excellent sources of
carotenoids

Polyphenols are no light weights either. It is NOT as though Vit C is
better than polyphenols weight for weight.  The polyphenols in an
apple recycle the Vit C that is present and make the EQUIVALENT Vit C
about 1000 mg. IMHO polyphenols are the way to get a the efficacy of
large doses of Vit C without the downside of overdosing.

>3. Polyphenols are also known as flavinoids or similar, with those funny
>names you often see Quentin writing about in this group. Like lutein,
>quercetin, hesperidin, zeaxanthin, or that real tongue twister, astaxanthin,
>one of the ones that comes from sea animals like salmon or prawns. There's a
>zillion of them, many that appear to do nothing, and heaps that are not
>understood at all, one way or the other.

The special thing about those unfamiliar names is that they represent
essential substances for the health of bodily organs and other bits
and pieces with familiar names.

Alpha carotene     -> lungs
Beta cryptoxanthin  -> cervix
Astaxanthin        -> beta-cells in pancreas
Hesperidin         -> raising HDL -> clear arteries
Quercetin          -> eyes

>So eat lots of veges and some fruit, and anything else you see Quentin
>recommending as being important.  It probably is!
[quoted text clipped - 7 lines]
>Annette
>Munching her way through life!

Best wishes, must go.

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Annette - 25 Oct 2005 14:37 GMT
Hi there Quentin,

Thanks for the info. As is patently obvious, I am not all that familiar with
this subject, and am grateful for the knowledgable input you have provided.

So when you say, "must go", just don't go too far away, or for too long,
will you?

Annette

> This post not CC'd by email
>  On Mon, 24 Oct 2005 16:53:48 GMT, "Annette" <acianthus@bigpond.com>
[quoted text clipped - 132 lines]
>
> Best wishes, must go.
Quentin Grady - 25 Oct 2005 20:02 GMT
This post not CC'd by email
On Tue, 25 Oct 2005 13:37:02 GMT, "Annette" <acianthus@bigpond.com>
wrote:

>Thanks for the info. As is patently obvious, I am not all that familiar with
>this subject, and am grateful for the knowledgable input you have provided.

G'day G'day Annette,

Nah,  you had it pretty right. It's just one of my personal things
that polyphenols etc don't get the press they deserve because for too
long they haven't been listed.  The situation is a bit like fibre.
There are polyphenols just as there are fibres. They aren't singular,
simple or as easy to study as some vitamin that can be synthesised in
a lab.

>So when you say, "must go", just don't go too far away, or for too long,
>will you?

I was rushing off to a meeting at work ... and I'm about to do so
again ... right now.

>Annette

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Chris J. - 25 Oct 2005 23:01 GMT
>G'day G'day Chris,
>
>Glad you liked it.  It can be a bit of chore preparing the tables.

I'm sure it must have been. Thanks for doing it.

>  Vit C is something I haven't looked at much in the past. Vit C is a
>water soluble antioxidant, whilst Vit E is fat soluble.  To form an
>antioxidant network where Vit C can recycle Vit E intermediaries are
>required.  The most obvious are the polyphenols.  Put simply, less
>antioxidants vitamins are required when the polyphenols are present
>since recycling occurs so I wasn't concerned about getting enough.  

>What people don't often realise is that vitamin supplements typically
>provide the antioxidant vitamins abeit in the wrong stereoisomers
>forms but omit the polyphenols to get the whole thing working
>coherently.  

I knew about the wrong stereoisomers, but not about the polyphenols.
Thanks!

BTW, I find it very interesting that as flavonoids, isoflavones and
ellagic acid are all Polyphenols, and thus anti-oxidants, a google on
ellagic acid turned up a great many claims that it's an anti-cancer
agent too.

It's found in quantity in blueberries, blackberries, raspberries, red
grapes, and strawberries.

I'm not sure, but I think that would make red wine a good source of it
too.

>As far as I can see there are three major reasons why food is a better
>source than supplements.
[quoted text clipped - 6 lines]
>C.  The unexpected risks associated with excessive doses appear
>diminished.

Unless, of course, you decide to dine on Polar Bear liver... :-)

>This may be because food sources are less prone to
>suppressing the functioning of closely related compounds.  For example
>a food that contains alpha and beta carotene is unlikely to the
>suppress the action of alpha carotene whereas a supplement containing
>beta carotene without alpha carotene is more likely to do so.

And that could, perhaps, be the reason for the results in that
beta-carotine cancer test that you mentioned a while back?  
Alan S - 26 Oct 2005 00:27 GMT
>>G'day G'day Chris,
>>
>>Glad you liked it.  It can be a bit of chore preparing the tables.
>
>I'm sure it must have been. Thanks for doing it.

I'd be interested to know how you set up the spaces Quentin.
I usually have to resort to filling all the gaps with dots.

Cheers, Alan, T2, Australia.
Signature

Everything in Moderation - Except Laughter.

Quentin Grady - 26 Oct 2005 09:02 GMT
This post not CC'd by email
On Wed, 26 Oct 2005 09:27:55 +1000, Alan S
<loralweightandcarbs@optusnet.com.au> wrote:

>>>G'day G'day Chris,
>>>
[quoted text clipped - 4 lines]
>I'd be interested to know how you set up the spaces Quentin.
>I usually have to resort to filling all the gaps with dots.

I used spaces.  

Tab spacings vary in .txt formats.  

>Cheers, Alan, T2, Australia.

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Alan S - 26 Oct 2005 00:30 GMT
>I knew about the wrong stereoisomers, but not about the polyphenols.
>Thanks!
[quoted text clipped - 9 lines]
>I'm not sure, but I think that would make red wine a good source of it
>too.

Puts a new slant on the benefits of elderberry wine; just
watch the additives if drinking with little old ladies who
keep it in the cellar.
Cheers, Alan, T2, Australia.
Signature

Everything in Moderation - Except Laughter.

Chris J. - 26 Oct 2005 06:28 GMT
>>I knew about the wrong stereoisomers, but not about the polyphenols.
>>Thanks!
[quoted text clipped - 14 lines]
>keep it in the cellar.
>Cheers, Alan, T2, Australia.

ROFL!!!!!!!!!!!!!!!!!!!!

My Grandmother used to make Elderberry wine, and used to a generous
amount of Vodka to, as she would say, "give it some body".

Hmmmm... Thanks to your post, I'm thinking of making a batch (sans
vodka!!!) after my trip. It's been quite a while since I've made wine,
but I still have my gear.
Quentin Grady - 26 Oct 2005 09:09 GMT
This post not CC'd by email
On Wed, 26 Oct 2005 09:30:22 +1000, Alan S
<loralweightandcarbs@optusnet.com.au> wrote:

>>I knew about the wrong stereoisomers, but not about the polyphenols.
>>Thanks!
[quoted text clipped - 6 lines]
>>It's found in quantity in blueberries, blackberries, raspberries, red
>>grapes, and strawberries.

G'day G'day Alan,

The stand out best source of ellargic acid is reported to be black
raspberries. There is a wine maker who uses them here, in another
province, but I've never seen any. I try to persuade my friendly berry
growers to put some in but as yet without success.

BTW my black mulberry has an incredible amount of fruit on this year.

>>I'm not sure, but I think that would make red wine a good source of it
>>too.
>
>Puts a new slant on the benefits of elderberry wine; just
>watch the additives if drinking with little old ladies who
>keep it in the cellar.

While it is a bit off topic, if Asian bird flu strikes I'll be
queuing up for Tamiflu like everyone else. If none is available I'll
be into the blackcurrant jam, elderberry wine and ginger to ease the
aches and pains not to mention nausea.

>Cheers, Alan, T2, Australia.

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Alan S - 26 Oct 2005 15:48 GMT
>G'day G'day Alan,
>
[quoted text clipped - 4 lines]
>
>BTW my black mulberry has an incredible amount of fruit on this year.

Hi Quentin

We've had a glut of strawberries here recently, they were
selling at AU$5 kg. I zapped them in the food processor and
filled up several ice-block trays for future use. They are
great in thickish yoghurt because a couple of strawberry
blocks turn a half cup of yoghurt into a sort of frozen
yoghurt by the time they thaw. Frozen blueberries have a
similar effect.

Maybe you could do the same with your mulberries. I used to
have a bush as a kid (I was really popular when we had to
feed silkworms in a school experiment:-), but haven't tasted
them since.

Maybe I'll try some in early February in Hawke's Bay:-)
Cheers, Alan, T2, Australia.
Signature

Everything in Moderation - Except Laughter.

Quentin Grady - 26 Oct 2005 09:00 GMT
This post not CC'd by email
On Tue, 25 Oct 2005 15:01:47 -0700, Chris J. <chris@noadress.com>
wrote:

>>C.  The unexpected risks associated with excessive doses appear
>>diminished.
>
>Unless, of course, you decide to dine on Polar Bear liver... :-)

LOL.

Natural doesn't make food safe. Yes. It needs saying.

>>This may be because food sources are less prone to
>>suppressing the functioning of closely related compounds.  For example
[quoted text clipped - 4 lines]
>And that could, perhaps, be the reason for the results in that
>beta-carotine cancer test that you mentioned a while back?  

The researchers weren't keen to find fault with their technique. In
consequence many explanations were published for the adverse result.
My own thoughts were that by using synthetic beta-carotene that is
trans beta-carotene which the body converts to Vit A, the functioning
of cis beta-carotene from dietary sources was obstructed in some way.
Recently I saw a suggestion that beta-cryptoxanthin is a bioflavonoid
that protects the lungs.  Perhaps the supplementing interfered with
its action. IMHO when it comes to bioflavonoids, variety is a good
thing.

Best wishes,

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Chris J. - 27 Oct 2005 07:54 GMT
>This post not CC'd by email
>
[quoted text clipped - 6 lines]
>
> Natural doesn't make food safe. Yes. It needs saying.

Hmmm.. does this mean that Castor beans, even organically grown, might
be unhealthy? Or even Castor Bean extract (otherwise known as Ricin)?
:-)

On a serious note, I have seen people taking all kinds of mega-doses
of herbs and supplements, claiming that "it's natural, so it's safe".
Ugh...

>>And that could, perhaps, be the reason for the results in that
>>beta-carotine cancer test that you mentioned a while back?  
[quoted text clipped - 4 lines]
>trans beta-carotene which the body converts to Vit A, the functioning
>of cis beta-carotene from dietary sources was obstructed in some way.

I'd certainly agree with that.
Quentin Grady - 27 Oct 2005 08:46 GMT
This post not CC'd by email
On Wed, 26 Oct 2005 23:54:17 -0700, Chris J. <chris@noadress.com>
wrote:

>> Natural doesn't make food safe. Yes. It needs saying.
>
>Hmmm.. does this mean that Castor beans, even organically grown, might
>be unhealthy? Or even Castor Bean extract (otherwise known as Ricin)?
>:-)

LOL.  I cracked up at the thought of some one suggesting ORGANICALLY
GROWN castor beans would be safe.  

G'day G'day Chris,

I'll store that gem for future use when we get one of the "it's all
natural so its healthy brigade."

>On a serious note, I have seen people taking all kinds of mega-doses
>of herbs and supplements, claiming that "it's natural, so it's safe".
>Ugh...

Added to that, the law is exceeding lenient in allowing supplement
manufacturers to claim a substance as natural.  The classic example is
Natural Vit E.  Naturally occurring Vit E is usually a mixture of
tocopherols with gamma tocopherol being present in the highest
amounts.  The regulations coerce the supplement manufacturers to state
amounts per capsule in IU which amounts to alpha-tocopherol
equivalents.  Currently the manufacturers are allowed to convert the
gamma tocopherol into alpha tocopherol and still call it natural.

Does the conversion give the correct stereoisomers for the tocopherol?
Well that is anyone's guess.

Best wishes,


Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

Chris J. - 28 Oct 2005 07:37 GMT
>This post not CC'd by email
>
[quoted text clipped - 6 lines]
>LOL.  I cracked up at the thought of some one suggesting ORGANICALLY
>GROWN castor beans would be safe.  

Well, you certainly wouldn't want the inorganic kind: all those
pesticides can be unhealthy.... :-)

>>On a serious note, I have seen people taking all kinds of mega-doses
>>of herbs and supplements, claiming that "it's natural, so it's safe".
[quoted text clipped - 11 lines]
>Does the conversion give the correct stereoisomers for the tocopherol?
>Well that is anyone's guess.

I've seen quite a bit of debate on Vitamin E, and the stereoisomer
issue seems to be a big one.

As for the conversion process, I can't back up what I'm about to say,
but for me it brings to mind the hydrogenation process that some
manufacturers put fats through, that gives us all those wonderful
triglycerides. Ugh.
Jefferson - 22 Oct 2005 07:04 GMT
> G'day G'day Folks,
>
[quoted text clipped - 41 lines]
> BTW.  The RDA, is currently about 60 to 80 mg.
> Someone can no doubt find an official figure.

The figures in the following article are developed from the Iowa Women's
Health Study.  I assume that the problem with vitamin C is that in some
tissue glucose and vitamin C compete for GLUT1.

Does supplemental vitamin C increase cardiovascular disease risk in
women with diabetes? -
http://www.ergogenics.org/ctox.html
The first quintile should be 71 rather than 171 mg/d since the total
from both food and supplements is only 85 mg/d in the first quintile.

I received the full report from Dr. Folsom. The relative risk for the
safest quintile for all vitamin C intake was a median of 139 mg/d for
diabetic women.

Relative risks (RRs) and 95% CIs for mortality from cardiovascular
disease, coronary artery disease, and stroke according to quintile of
vitamin C intake from food and supplements in postmenopausal women with
diabetes in the Iowa Women’s Health Study, 1986–2000

Quintile of median vitamin C intake from food and supplements (mg/d)
1 (85) 2 (139) 3 (189) 4 (279) 5 (667)

A thread on the topic - http://tinyurl.com/d2cqc.

Frank
Quentin Grady - 22 Oct 2005 09:08 GMT
This post not CC'd by email
On Sat, 22 Oct 2005 02:04:18 -0400, Jefferson
<croom1935@netscape.net> wrote:

>The figures in the following article are developed from the Iowa Women's
>Health Study.  I assume that the problem with vitamin C is that in some
[quoted text clipped - 21 lines]
>
>Frank

G'day G'day Frank,

Thanks.  It is great to see this study of 15 years duration shows
increased Vit C from diet is not detrimental.  

Supplements are however a different story. With supplements being
topical at the moment this provides an opportune example of the
hazards of supplementation.

It would appear that it is a bit like red wine and many other things
that illustrate the famous "J" curve.  Less than 100 mg is beneficial
but over that is detrimental.

Best wishes,

Signature

Quentin Grady       ^  ^  /
New Zealand,       >#,#< [
                   / \ /\    
"... and the blind dog was leading."

http://homepages.paradise.net.nz/quentin

 
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