> > A periodontist recommended that I have the innermost left lower molar
> > removed because of infection and bone loss. When I went in to have the
[quoted text clipped - 20 lines]
>
> Steve
And John wrote in his recent reply:
> Osteonecrosis of the jaw is well documented in patients who have taken
> bisphosphonates, although it is a relatively new cause of osteonecrosis as
[quoted text clipped - 8 lines]
>
> Good topic for discussion.
I raised this issue in smd when it "first" hit the "news" in March (?)
two years ago.
~~~~~~~~~~~~
Newsgroups: sci.med.dentistry, alt.support.jaw-disorders
From: The Webby [address deleted]
Date: Wed, 23 Mar 2005 00:00:07 GMT
Local: Tues, Mar 22 2005 5:00 pm
Subject: Avascular necrosis of TMJ
http://www.niams.nih.gov/hi/topics/avascular_necrosis/
In my case, it was (later) determined that I suffered bilateral
avascular necrosis of the temporomandibular joints as a result of
surgical complications from surgical error (orthognathic surgery). The
joints were destroyed and thus began the saga of my chronic and
permanent TMJ disability and disease.
If you search Google Groups for "osteonecrosis jaw" you'll discover
posts that you may not have paid attention to in the past -- or maybe it
was even *you* who put the posts up! Either way, it's an interesting
review.
The subjects of TMJ avascular necrosis and osteonecrosis of the
maxillofacial area (jaw/jawbone) are or should be matters of interest to
dental related newsgroups.
II'm just tossing these topics out to see if there's any interest in
getting a discussion going. Turn on your television and count how many
times you see an advertisement for Fosamax (alendronate) in one evening.
I watch relatively little television but I sure see a lot of Fosamax
pushing.
Webby
~~~~~~~~~~~~~
I believe it is a very good topic for discussion!!!
There is the old saying that if it happens 1% of the time and it happens
to you ... it happens 100% of the time. Nancy not only needs to know
what the risks are *if* she has the tooth extracted ... she also needs
to know what sort of risks are associated with treatment options *if*
she ends up with the worst case scenario.
Unfortunately, the problem as I see it is more like this:
When doctors want their patients to be treated with these drugs, they
need to not only mention the dental risks ... they need to get the
information to their patients about how their Humpty Dumpties will be
put back together again if they fall off the wall... and what the risks
of *that* might be.
Webby
Derek Lawler - 08 Jun 2007 16:23 GMT
Steve and Webby,
Thanks for your replies to my query. You have all been quite helpful.
Nancy
Steven Bornfeld - 08 Jun 2007 21:46 GMT
>>> A periodontist recommended that I have the innermost left lower molar
>>> removed because of infection and bone loss. When I went in to have the
[quoted text clipped - 88 lines]
>
> Webby
Sadly, there are no good answers to the problem of bisphosphonate
related osteonecrosis (BON) that I have heard of. Treatment is
palliative. Some patients tolerate it well, some not well at all.
It is easy to wonder why a drug with these potential sequellae is used
so widely. To grossly oversimplify, on the one hand the magnitude of
the problem is often not appreciated until considerably later (as you
know from personal experience) or there is actual malfeasance in the
dispensing of available information (see Vioxx). On the other hand, the
conditions being treated are significant. The morbidity associated with
hip fractures in the osteoporosis patient are very serious.
Furthermore, since the bulk of the BON cases seen so far are patients
receiving intravenous bisphosphonates for metastatic breast, prostate
and other bone cancers, the calculus for risk of treatment is not only
very complicated, but also changing continually.
Finally, an increasing number of BON cases are arising in patients with
no apparent history of trauma, so the benefit of avoiding necessary
dental treatment is even harder to know.
Unfortunately, the surgeon has to think not only of the medication, the
reason it is being administered, the dental treatment, and the patients'
needs and desires, but also of the lawyer lurking around the corner.
They learned about BON very quickly.
Steve