Not that I have heard of.  Are you taking anything for the pain like
ibuprofen/advil/aleve?  If the pain seems to be worsening, contact the
dentist.  There is always a slight chance of a flare-up (swelling related to
an infection), but it sounds to me like post-op inflammation.  The files
used to clean the canals sometimes extrude beyond the tooth into the
periodontal ligament.  The files can be rather sharp, so imagine someone
taking a needed and jabbing under your thumbnail over and over again.
Wouldn't feel too good, would it?  Same thing with the files going into the
periodontal ligament.  Again, some people react differently than others, but
I don't think your seizure medication has to do with it.