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Medical Forum / General / Dentistry / January 2006

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A Migraine Treatment Patients Can Really Sink Their Teeth Into

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Tim Dixon - 28 Dec 2005 16:13 GMT
From Practical Neorlogy, October 2005

By Andrew Blumenfeld, MD and James Boyd, DDS

Conventional pharmacotherapies for migraine headache can have undesirable
systemic side effects, and medications currently accepted for prophylactic
treatment (e.g., propranolol, amitriptyline, verapamil) rarely have a better
than 55 percent efficacy. Furthermore, the potential teratogenic effects of
some migraine prophylactic agents (e.g., divalproic sodium) make birth
control a necessity in women of childbearing age. Along with these
shortcomings, compliance becomes an issue; frequently, transformation to
chronic daily headache occurs.

A new non-pharmacologic method for prophylactic treatment of medically
diagnosed migraine pain as well as tension-type headaches, called the
Nociceptive Trigeminal Inhibition Tension Suppression System, is an
intra-oral device that reduces trigeminally-mediated muscular activity and
the resultant noxious afferent input. In patients with migraine and
tension-type headache, pericranial muscle tenderness (specifically of the
temporalis) is a common complaint, frequently detectable upon palpation.
Intraoral devices have been used to protect teeth from the intense
hyperactivity of the trigeminally-innervated muscles of mastication,
primarily the temporalis and masseter muscles.

These devices have no systemic effects and are thus safe in pregnancy,
lactation and in elderly patients on multiple other medications. There are
two types of intraoral devices now currently available: the traditional
full-occlusal splints and dis-occlusion splints. The full-occlusal splint
covers all of the teeth. Such splints still allow hyperactivity to
perpetuate or intensity for as least 50 percent of patients by providing the
necessary resistance to clench on. A dis-occlusion splint allows only
reciprocating anterior incisor contacts, thereby inhibition
trigeminally -innervated pericranial muscular contraction (most notably, of
the temporalis) to less than a third of maximum.

Nocturnal trigeminal motor hyperactivity and the resultant noxious afferent
input can be interrupted by a dis-occlusion splint such as the NTI and
allows the practitioner to give his patient a non-pharmaceutical option for
migraine prevention. The NTI device is essentially a prefabricated matrix
which a dentist custom fits to the patient. When used during times of
muscular parafunction (i.e., during nocturnal jaw clenching, a common trait
of migraineurs) the NTI device has been shown to reduce migraine events by
77 percent in 82 percent of subjects.
Mark & Steven Bornfeld - 28 Dec 2005 16:18 GMT
> From Practical Neorlogy, October 2005
>
[quoted text clipped - 39 lines]
> of migraineurs) the NTI device has been shown to reduce migraine events by
> 77 percent in 82 percent of subjects.

    Best to you and yours, Stovie--keep that pipe warm!!

Steve

Signature

Mark & Steven Bornfeld DDS
http://www.dentaltwins.com
Brooklyn, NY
718-258-5001

Mark & Steven Bornfeld - 28 Dec 2005 16:19 GMT
>> From Practical Neorlogy, October 2005
>>
[quoted text clipped - 45 lines]
>
> Steve

    Sorry Tim--I replied to the wrong post!

Happy New Year!

Steve

Signature

Mark & Steven Bornfeld DDS
http://www.dentaltwins.com
Brooklyn, NY
718-258-5001

Tim Dixon - 28 Dec 2005 16:37 GMT
>>> From Practical Neorlogy, October 2005
>>>
[quoted text clipped - 50 lines]
>
> Steve

Thats ok Steve, i'll keep my pipe warm too.

For those of you who are NTI providers that might be interested, I will be
happy to provide you with a DVD I produce of Dr. Blumenfeld, free of charge
if you send me your postal mailing instructions to my private e-mail. (just
take out the nospam stuff).

The DVD runs one hour in duration and Dr. Blumenfeld will walk you through
the medical world of medically diagnosed migraine using the FDA approved NTI
for the prevention of migraine.  He will show you how to make the diagnosis,
the kinds of treatments currently available, and how the NTI fits into that
model.  He also covers marketing of the NTI to Neurologists.

This DVD footage was filmed by me during the May 2005, ABC's of TMD's, put
on by Dr. Boyd and Dr. Glassman and sponsored by Keller Labs and is usually
only available to attendees of those courses.  However, feeling generous and
because I think highly of all of you I have decided I will offer you this so
that perhaps it may enhance your practice and open your eyes and mind to the
world of neorolgy.

Dr. Boyd currently practices with Andrew Blumenfeld, MD, (a neurologist
specializing in migraine) at The Headache Center, part of the Neurology
Center at the Scripps Hospital campus in Encinitas, California and lectures
throughout the U.S. and internationally.

Dr Blumenfeld is a member of the American Academy of Neurology and the
American Headache Society. He has published widely in areas of headache and
has been an active researcher in headache and multiple sclerosis. He has
wide experience in botulinum toxin therapy, and is director of the Headache
Center of Southern California
Amatus Cremona - 28 Dec 2005 17:55 GMT
Tim,

I don't believe I have that one in my collection.  Could you send me a copy
?

Signature

/

Amatus

/

>
>>>> From Practical Neorlogy, October 2005
[quoted text clipped - 84 lines]
> has wide experience in botulinum toxin therapy, and is director of the
> Headache Center of Southern California
Tim Dixon - 28 Dec 2005 18:02 GMT
> Tim,
>
> I don't believe I have that one in my collection.  Could you send me a
> copy

No you don't have this one and of course I'll send one, just send me your
addie since I can't seem to locate it at the moment.

This DVD is definitely worth the hour of your time to watch it.  I guarantee
you will not look at migraine the same way you use to.
JanD - 28 Dec 2005 19:14 GMT
>> Tim,
>>
[quoted text clipped - 6 lines]
> This DVD is definitely worth the hour of your time to watch it.  I
> guarantee you will not look at migraine the same way you use to.

Jim got in touch with me when he learned I had been a patient of Diamond
Headache Clinic for years. He was working with my doctor, Dr. Fritag, to get
the NTI FDA approved. Unfortunately, the NTI didn't help my headaches. GOD
BLESS ALL OF THOSE IT DID HELP. It does not help everyone. I wish it were
so.

Sadly, just my experience.

Jan
stephanieplum@iloveagoodbook.com - 29 Dec 2005 07:54 GMT
>Jim got in touch with me when he learned I had been a patient of Diamond
>Headache Clinic for years. He was working with my doctor, Dr. Fritag, to get
>the NTI FDA approved. Unfortunately, the NTI didn't help my headaches. GOD
>BLESS ALL OF THOSE IT DID HELP. It does not help everyone. I wish it were
>so.

I've had mine for nearly 2 weeks. My use of NSAIDS is down to zero,
(they make me dizzy and puke anyway). However, now that the NTI has
reduced my daily pain and headache I am less dizzy and less anxious.
PAIN can make you dizzy and anxious DOH!

I *love* taking the NTI off my teeth in the morning, I can then
clearly feel the teeth that are *used to* clenching and grinding.

Here's a question for dental types (please use plain English okay?)
why do my clenching teeth feel numb and weird when I take the NTI off
and start daytime clenching?

Stopping the nightime clenching is FAB - my pain is reduced therefore
I clench less during the day, but I still clench whenever I'm
concentrating, really happy or really pissed off.

PS I thought that the teeth on the lower jaw under my incisors were
getting worn because I'm nearly 40 and that was just par for the
course. My new dentist had one look and told me I was grinding them. I
didn't believe her at first. Then she asked me to think about it. THEN
I remembered actually waking myself up by clashing the lower teeth
with the upper teeth and freaking out about it because the lower teeth
were out in front of the upper teeth and supposedly my jaw was way too
forward. That has happened a few times a year for many years. As well
as the nocturnal dreams I have that all my teeth are falling out and
hurting. Btw, two fillings, straight teeth - high strung 39 year old
woman :)

I LOVE my NTI.
Tim Dixon - 29 Dec 2005 15:08 GMT
> I've had mine for nearly 2 weeks. My use of NSAIDS is down to zero,
> (they make me dizzy and puke anyway). However, now that the NTI has
> reduced my daily pain and headache I am less dizzy and less anxious.
> PAIN can make you dizzy and anxious DOH!

Thats great news to hear.

> I *love* taking the NTI off my teeth in the morning, I can then
> clearly feel the teeth that are *used to* clenching and grinding.
>
> Here's a question for dental types (please use plain English okay?)
> why do my clenching teeth feel numb and weird when I take the NTI off
> and start daytime clenching?

Probably because you had previously been compacting your teeth within their
sockets on a regular basis.  This should resolve itself as you acclimate to
the appliance.

> Stopping the nightime clenching is FAB - my pain is reduced therefore
> I clench less during the day, but I still clench whenever I'm
> concentrating, really happy or really pissed off.

You may need to also have a day time appliance made.

> PS I thought that the teeth on the lower jaw under my incisors were
> getting worn because I'm nearly 40 and that was just par for the
[quoted text clipped - 9 lines]
>
> I LOVE my NTI.

Glad to hear you love your NTI.  I would suggest you ask your treating
dentist about a daytime appliance.  You may not need it all the time, but
can easily pop it in when you feel yourself clenching.

Keep us posted.
JanD - 29 Dec 2005 19:44 GMT
I have both the night time and day time NTI. You might want to try that.

Good luck to you. Happy you have found relief!

Jan

>>Jim got in touch with me when he learned I had been a patient of Diamond
>>Headache Clinic for years. He was working with my doctor, Dr. Fritag, to
[quoted text clipped - 32 lines]
>
> I LOVE my NTI.
Tim Dixon - 29 Dec 2005 19:50 GMT
"JanD" <JanD@insightbb.com> wrote in message
news:t0Xdsf.658245$x96.407361@attbi_s72...

No one asked you.
JanD - 29 Dec 2005 20:26 GMT
> "JanD" <JanD@insightbb.com> wrote in message
> news:t0Xdsf.658245$x96.407361@attbi_s72...
>
> No one asked you.

I don't need to be asked to post here.
Tim Dixon - 29 Dec 2005 20:28 GMT
"JanD" <JanD@insightbb.com> wrote in message
news:QDXsf.6258362$x96.51395@attbi_s72...

ignore
Robert  Morien - 31 Dec 2005 09:39 GMT
> don't

re: Jan loves Tim Dixon   Thread Hijacking in progress
pellmellwillynilly@hotmail.com - 31 Dec 2005 21:28 GMT
> "JanD" <JanD@insightbb.com> wrote in message
> news:t0Xdsf.658245$x96.407361@attbi_s72...
>
> No one asked you.

Hm. Stephanie asked the "dental types" to reply. How does "dental
types" include you but not Jan? Am I unaware of some degrees you've
earned since getting better from the AGELK? In fact, if you're really
all better, why ARE you back in this newsgroup if it's not for dental
groupies? If you're not here to learn or get better, you must also be a
groupie. Last I heard, you sho warn't no dentist.
Tim Dixon - 31 Dec 2005 23:10 GMT
<pellmellwillynilly@hotmail.com> wrote in message
news:113606ds4536.354316.188770@g14g2000cwa.googlegroups.com...

cut some insane rant
stephanieplum@iloveagoodbook.com - 31 Dec 2005 05:28 GMT
How are the nightime and the daytime NTI different? How does the
dentist know how to make them different? What do they do to the NTI to
make it different to the nightime NTI?

I got my nightime NTI made during the day, not sleeping of course. How
would it be different to any made for me for daytime use?

Would like some more info before I lay out more $$$$$.

Stephie

>I have both the night time and day time NTI. You might want to try that.
>
>Good luck to you. Happy you have found relief!
>
>Jan
Tim Dixon - 31 Dec 2005 15:28 GMT
> How are the nightime and the daytime NTI different? How does the
> dentist know how to make them different? What do they do to the NTI to
[quoted text clipped - 6 lines]
>
> Stephie

While the Standard NTI-tss device can be worn indefinitely (while sleeping),
the NTI-tss Daytime Device is recommended for the migraine sufferer (in
addition to the use of the Standard Device) for 4 to 8 weeks during waking
hours (but still impossible to use while eating, thereby preventing
supraeruption).  The Daytime Device takes advantage of the naturally
protective nociceptive trigeminal inhibition reflex which suppress the
powerful temporalis muscles. It is the protective reflex experienced when
biting down, expecting something soft, but encountering something hard.

Migraine and tension-type headaches are both medically diagnosed benign
conditions.  These conditions are confirmed to be benign only after thorough
medical tests have confirmed that there are no disease processes that are
the cause of the patient's pain.   An NTI-tss device should only be used for
migraine and/or tension-type headache reduction after the condition has been
medically diagnosed.

The protocol for delivery of an NTI-tss device for a migraine and/or
tension-type headache sufferer is identical to that for the muscular
parafunction (bruxism/TMD) patient.  However, unlike the bruxism/TMD
patient, where the use of a standard NTI-tss device during sleep alone is
highly effective, the migraine and/or tension-type headache sufferer will
most likely require a "daytime" NTI-tss device as well, for the most stable
and predictable results.

Although there is little, if any, intense pericranial muscular contraction
throughout the day, the presence of an NTI-tss daytime device (for the first
four to six weeks of treatment) is essential.  Stressful situations (that
is, a "trigger" for a migraine sufferer) can occur at any time.  A "trigger"
is really an activation of the patient's sympathetic nervous system. The
intrafusal fibers of spindle organs that reside within the fatigued
pericranial musculature are innervated by the SNS.  Until the musculature
has had adequate time to recover from its chronic intense nocturnal
parafunction (four to six weeks with regular nighttime NTI-tss use), the
intrafusal fibers of those spindles still reside within fatigue,
dysfunctional musculature and may hyper contract, which is highly painful
and may be the source of the migraine pain. (See:  Sympathetically
Maintained Spindular Dysfunction: A Model for the Etiology of Chronic
Tension-type Headache and Migraine.

The presence of a daytime NTI-tss allows the patient to gently "tap" their
lower incisors on the Discluding Element during stressful events, thereby
exploiting the nociceptive trigeminal inhibition (NTI) reflex, which serves
to suppress and relax the pericranial musculature and disrupt the
neuromuscular mechanism leading to the migraine pain.

A daytime NTI-tss is not necessarily the same as the patient's standard
nighttime device.  Since parafunctional excursive and protrusive activity
during the daytime is insignificant, the degree of vertical opening and
anterior extension of the Discluding Element can be reduced for the patient's
comfort (that is, it should NOT act as an irritant to the patient, thereby
becoming a trigger itself!).   A daytime device (above) would ideally
provide minimal posterior disclusion in centric and in slight excursive
movements.  A daytime NTI-tss device will typically provide for an incisal
occlusal stop on the lingual side of maxillary incisors, contacting with the
mandibular central incisors.

In moderate excursive or protrusive  movement, canine or posterior teeth may
contact each other(circled above), allowing for the perpetuation of
temporalis dysfunction (the patient usually has no awareness of the
activity, even in the daytime).  These potential contacts could allow for
intense muscular activity, making the daytime design contraindicated for
nighttime use.  If the patient complains of new symptoms during the day
following daytime use, it is most likely due to their excursive activiities.
If so, incease vertical slightly if tolerated.

A "daytime" NTI-tss is recommended for at least the first four to eight
weeks of treatment for the migraine and/or tension-type headache patient (in
addition to use of a nighttime NTI-tss), to be worn at all times, except for
when eating.  Following that time, daytime use is optional for the patient.
As long as the patient continues to remove the daytime device while eating
(which provides alveolar stimulation, thereby preventing posterior
supra-eruption), there are no adverse dental effects.  As the nocturnal
parafunctional intensity continues to be suppressed night after night, the
abilitiy to "trigger" a migraine during the day decreases.  After 6 to 8
weeks, the daytime NTI-tss is no longer necessary, because the
"pre-existing" condition (which was being prepertuated by nightly activity)
of pericranial spindular dysfunction, no longer exists.

The need for occlusal equilibration may become obvious during this time.
When the patient removes their daytime device, they may become highly aware
of occlusal interferences.  These are SNS irritants as well and should be
equilibrated!  Otherwise, the patient will find themselves always wanting to
wear the daytime device (because their teeth feel awkward).

Although the daytime design may be more pleasing to the patient, it is
important to stress to them that if canine or posterior clenching is
possible in protrusive or excursive movement, it is not to be worn while
sleeping (within a night or two,  the patient will "defeat" it, that is,
seek out and find teeth to clench on in excursive positions, thereby making
their condition  worse!)
stephanieplum@iloveagoodbook.com - 01 Jan 2006 08:38 GMT
>> How are the nightime and the daytime NTI different? How does the
>> dentist know how to make them different? What do they do to the NTI to
[quoted text clipped - 12 lines]
>hours (but still impossible to use while eating, thereby preventing
>supraeruption).  

Thanks Tim. I know that stuff is on a certain website. But, not being
a dental type, I don't get it. I don't want to get it kwim? Can you
explain your quote in plain English?

Also what does a daytime NTS look like? My nighttime one looks really
stupid. Are the day time NTI's any "cuter"? ;)

Also, please tell me what supra eruption means. I'm thinking it means
that a tooth goes nuts and grows longer than it ought to. If that is
the case, my molar on the upper right (only molar I have left after
wisom teeth removal) feels longer than the rest of the teeth. It is
also my latest and greatest favourite molar to clench.
Tim Dixon - 01 Jan 2006 13:22 GMT
>>> How are the nightime and the daytime NTI different? How does the
>>> dentist know how to make them different? What do they do to the NTI to
[quoted text clipped - 26 lines]
> wisom teeth removal) feels longer than the rest of the teeth. It is
> also my latest and greatest favourite molar to clench.

The DayTime NTI is smaller and less noticeable and is produced from a blank
matrix that is designed to be used just for daytime.  Your dentist will have
one on hand and knows how to make one.  Only he can decide if you really
need it, but if you tell him what you told us its likely he will make one
for you.

As far as supereruption goes, forgot about it.  You don't/won't have either
device in long enough for that to ever occur.
Amatus Cremona - 01 Jan 2006 21:46 GMT
>As far as supereruption goes, forgot about it.  You don't/won't have either
>device in long enough for that to ever occur.

But, you can get repositioning of the joint This feels like
super-eruption.

Amatus

>>>> How are the nightime and the daytime NTI different? How does the
>>>> dentist know how to make them different? What do they do to the NTI to
[quoted text clipped - 35 lines]
>As far as supereruption goes, forgot about it.  You don't/won't have either
>device in long enough for that to ever occur.
stephanieplum@iloveagoodbook.com - 03 Jan 2006 07:39 GMT
>>As far as supereruption goes, forgot about it.  You don't/won't have either
>>device in long enough for that to ever occur.
[quoted text clipped - 3 lines]
>
>Amatus

Thanks again.

But why does the only molar I have left on my bad side feel longer and
nastier than it ever did? I have molars on all the other sides. On my
bad side (upper right) this nasty molar is pissing me off. I thought
when I had the final wisdom tooth extracted on the bad side that this
irritation/pain would go. The NTI helps, but the TOOTH pisses me off.
It is my favourite daytime and nighttime clenching tooth.

Further, the wisom tooth extraction site which lies behind my most
hated tooth doesn't feel fully healed. I can feel a cleft like thing
on the gum on the underside. There is also a big chunk of bone left
behind that feels like a tooth is hiding in there somewhere.

And also, again, in plain Enlish what TF IS super eruption? Sounds
funky.
Amatus Cremona - 03 Jan 2006 12:35 GMT
> But why does the only molar I have left on my bad side feel longer and
> nastier than it ever did?

Once the muscle spasms go away, the joint will often re-position to a more
relaxed postion.  This postion is often higher and further back in the
socket.  Therefore, the entire jaw pivots around a different radius.  The
end result is usually a back tooth which hets too hard and needs adjustment.

> I have molars on all the other sides. On my
> bad side (upper right) this nasty molar is pissing me off. I thought
> when I had the final wisdom tooth extracted on the bad side that this
> irritation/pain would go. The NTI helps, but the TOOTH pisses me off.
> It is my favourite daytime and nighttime clenching tooth.

This tooth is likely your latero-protrusive bracing postion posterior
contact.  You probably need a minor occlusal adjustment to eliminate the
ability to clench in this positon.  Maybe not.

> Further, the wisom tooth extraction site which lies behind my most
> hated tooth doesn't feel fully healed. I can feel a cleft like thing
> on the gum on the underside. There is also a big chunk of bone left
> behind that feels like a tooth is hiding in there somewhere.

Has it been two years since the extraction , yet?  Those often take that
long to become smooth.

> And also, again, in plain English what TF IS super eruption? Sounds
> funky.

When the tooth erupts further than it would naturally do in function.
Occurs when the opposing tooth is absent, or the occlusion is way off.

BTW, I am not my sista, so you don't need the vulgarity when speaking to me.
[Even if it is just the initials].

Signature

/

Amatus

/

Tim Dixon - 30 Dec 2005 14:20 GMT
>>>> From Practical Neorlogy, October 2005
>>>>
[quoted text clipped - 83 lines]
> has wide experience in botulinum toxin therapy, and is director of the
> Headache Center of Southern California

I guess none of you are too interested in this offer, since I have only had
one taker.  Or maybe you didn't see it because it was buried in this post.
Come on boys what are waiting for?
Wham_B - 31 Dec 2005 21:05 GMT
>I guess none of you are too interested in this offer, since I have only had
>one taker.  Or maybe you didn't see it because it was buried in this post.
>Come on boys what are waiting for?

Check your mail again.
You should have one from me.

--
Whamatus
Take out the G'RBAGE
wubbabubbazG@RBAGEyahoo.com
Tim Dixon - 31 Dec 2005 21:16 GMT
>>I guess none of you are too interested in this offer, since I have only
>>had
[quoted text clipped - 3 lines]
> Check your mail again.
> You should have one from me.

I got one mail from you if thats the one in question?  To which I replied
;-)
 
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