Medical Forum / General / Dentistry / November 2005
Streptomycin changed the world's health
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The Webby - 07 Nov 2005 05:19 GMT Another thread was getting a bit lost in the confusion. So I cut and pasted its most recent reply and my comments into a new thread.
Streptomycin
http://ur.rutgers.edu/focus/article/Albert+Schatz,+co-discoverer+of+strep tomycin,+dies+at+84/1504/
> Albert Schatz, co-discoverer of the antibiotic streptomycin as a graduate > student at Rutgers, died Jan. 17 at age 84. Selman Waksman, with whom Schatz > studied, is credited as the other co-discoverer. While working with Waksman, > Schatz demonstrated that streptomycin was active against the bacterium that > causes tuberculosis. http://www.guardian.co.uk/weekend/story/0,3605,823114,00.html
> People called TB the white plague, and feared it more than the bubonic > plague. Highly contagious, essentially incurable and capable of causing death > decades after infection, it has decimated mankind since the time of the > pharaohs. In the past two centuries alone, it has killed more than one > billion people - more than every war, famine and other epidemic put together. > Chopin, Orwell, Emily Brontë, DH Lawrence and Chekhov all died of the > disease. Without the discovery and usage of streptomycin, what would have happened to the population of this planet? Whether or not anyone agrees with the ideas and opinions of any particular person of science, one can not dispute the benefits of streptomycin. And ... neither can one dispute the serious side effects of that same antibiotic; a particularly strong reason why he recognized the value of "that book", "The TMJ Iatroepidemic". Dr. Schatz was perfectly aware of the impacts humanity faces when handling the double edged sword of technology. And whether or not people agreed with his research in various areas of science and medicine, people should know that his heart was in the "right" place.
Carefully and with serious concern, strolling amongst the masked (and somewhat anonymous) patients in a TB ward during the 1970s after the Vietnam Refugees ("The Boat People") arrived in the USA ... I had no idea that one day I would have a direct connection to the man who saved the lives of so many who suffered from tuberculosis ... it simply amazes me that my ever so ordinary life has been touched by so many incredibly extraordinary people. And every once in a while, I am reminded that my seemingly ordinary life is really not so ordinary at all.
Sincerely, The Webby
In article <Tuwbf.8858$dU6.6266@trnddc03>, "ares" <ares@verizon.net> wrote:
> Darn..........yeah, I'm having a problem with dentistry; I just don't > believe in much of what is going on. The office I'm at was bought by > someone else and they seem to be focused on 'fear of the dentist', and > offering sedation, which I don't do except for a Rx for valium and tell them > to have someone drive them. Well, I didn't have cases like that on a > regular basis, and my attitude is get over it or go to someone who > specializes in that, with the possible exception of children, and they go to > a pedo, and I don't even know if they do sedation here on kids. We now have > Zoom and I'm scared of the darn thing; nobody's mentioned if devitalizing a > pulp is a possibility with this thing. I'm so disillusioned. And then > there's people placing veneers on teeth that have class 3's in them and I > often then find decay in the class 3's. And then there's the posterior > class 2 composites; I rarely see one that looks right. > Oh well, I can retire any time I want but I'm just trying to keep busy > while I still have the ability to work a bit more. > The name sounds familiar but not sure I'd heard of Dr. Schatz. > ares > > "The Webby" <nospamattmjiatroepidemicnospam@san.rr.com> wrote in message > news:nospamattmjiatroepidemicnospam-64049B.08082306112005@news-lb-01.socal.r > r.com... > > > > I was deeply saddened to learn that Albert Schatz, Ph.D. died on Jan. > > > 17, 2005. > > > > > > Webby > > > > Albert Schatz discovered streptomycin. Many of you probably thought the > > distinction belonged to Waksman (widely taught) but that was not really > > true. > > > > If many of today's young people had a better understanding of how recent > > it was that we didn't have answers to so many of the infectious diseases > > that were killing people in numbers too incredible to grasp -- maybe we > > would be concerning ourselves with matters more important that > > ultra-white teeth. > > > > Webby Vaughn - 07 Nov 2005 11:25 GMT > http://www.guardian.co.uk/weekend/story/0,3605,823114,00.html > >> People called TB the white plague, and feared it more than the bubonic >> plague. And it is amazing how quickly it was forgotten. It is only in this generation that TB was mastered, yet nobody seems to remember the effect it had on on our lives. We had a nationwide network of public hospitals dedicated to that one disease. I live less than a mile from the last one remaining in is original use.
>>Highly contagious, essentially incurable and capable of causing death >> decades after infection, it has decimated mankind since the time of the >> pharaohs. In the past two centuries alone, it has killed more than one >> billion people - more than every war, famine and other epidemic put together. >> Chopin, Orwell, Emily Brontë, DH Lawrence and Chekhov all died of the >> disease. ...as well as my mother. For years at a time I was only allowed to see her from a distance; her locked up inside the hospital waving out the window to us kids sitting outside on the lawn.
All communicable diseases have a profound socal effect. Fortunately, I was young enough to be oblivious to that effect on my own life. Having TB in your house effectively made you a social outcast. Would you allow your kid to play with a kid whose mother had AIDS? It was the same deal then.
I don't remember the problem coming up for my mother, but I wonder how TB patients got dental care?
Vaughn
Steven Bornfeld - 07 Nov 2005 14:23 GMT >>http://www.guardian.co.uk/weekend/story/0,3605,823114,00.html >> [quoted text clipped - 4 lines] > generation that TB was mastered, yet nobody seems to remember the effect it had > on on our lives. If only...
http://www.priory.com/cmol/TBMultid.htm
Steve
We had a nationwide network of public hospitals dedicated to
> that one disease. I live less than a mile from the last one remaining in is > original use. [quoted text clipped - 19 lines] > > Vaughn
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Vaughn - 08 Nov 2005 11:15 GMT >> And it is amazing how quickly it was forgotten. It is only in this >> generation that TB was mastered, yet nobody seems to remember the effect it [quoted text clipped - 3 lines] > > http://www.priory.com/cmol/TBMultid.htm Yes, perhaps "mastered" is a bit strong, but at least I avoided the word "cured". The article you posted mentioned that we progressed from a 50% to a 98% cure rate; that is pretty damn good! That said, new drug-resistant strains remain a threat.
I am fascinated by the three-way collision of science, politics, and public policy. We see it every day here on smd (you know, fluoride and the "a" word). It is amazing that by law, a person in the US is generally not allowed to "have" TB. Your doctor must report your case, you must receive treatment, and your contacts will be traced to see if you have infected anyone else. Yet we give AIDS a very different treatment; don't ask, don't tell. It is the curious interaction of plague and politics.
Vaughn
Tim Dixon - 08 Nov 2005 14:10 GMT >>> And it is amazing how quickly it was forgotten. It is only in this >>> generation that TB was mastered, yet nobody seems to remember the effect [quoted text clipped - 18 lines] > > Vaughn And yet yesterday I saw an ad on TV for some new drug, and when they got to the side-effects, one was TB. So we almost knock it out, and along comes some drug company making drugs that can cause it. I don't get it. Witth all the problems lately with drugs gone bad, I wouldn't be surprised if we saw an increase of TB cases. Sorry I can'tt recall the name of the drug, but if I see it again I'll post it.
Amatus Cremona - 08 Nov 2005 14:49 GMT > And yet yesterday I saw an ad on TV for some new drug, and when they got > to the side-effects, one was TB. So we almost knock it out, and along > comes some drug company making drugs that can cause it. I don't get it. > With all the problems lately with drugs gone bad, I wouldn't be surprised > if we saw an increase of TB cases. Sorry I can't recall the name of the > drug, but if I see it again I'll post it. Since TB is an infectious process, they must be listing a side effect where inactive TB becomes active again.
There is a serious problem in some regions where TB is on the increase again. The problem is that many TB Patients stopped taking their antibiotics once they began to feel better. They had a small nexus of more resistant bugs still sitting in the lower lobes of the lungs. That colony can remain dormant for decades. Then, as the patient gets older or becomes ill, the colony becomes active and causes full blown TB again. Only this time with more resistant bugs.
I was told that some US cities have passed laws that allow the police to incarcerate infected individuals (with TB) until they finish taking their full dosage of antibiotics.
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> >>>> And it is amazing how quickly it was forgotten. It is only in [quoted text clipped - 26 lines] > if we saw an increase of TB cases. Sorry I can'tt recall the name of the > drug, but if I see it again I'll post it. The Webby - 08 Nov 2005 15:27 GMT > > And yet yesterday I saw an ad on TV for some new drug, and when they got > > to the side-effects, one was TB. So we almost knock it out, and along [quoted text clipped - 17 lines] > incarcerate infected individuals (with TB) until they finish taking their > full dosage of antibiotics. If our immune system is compromised, we can't fight off illnesses as our bodies were intended. AIDS is responsible for much of the TB outbreak globally. I think its been reported that 5000 people die each day (around the world) from TB.
As for Amatus' comment about the police, we need only remember this word:
quarantine
n 1: enforced isolation of patients suffering from a contagious disease in order to prevent the spread of disease 2: isolation to prevent the spread of infectious disease v : place into enforced isolation, as for medical reasons; "My dog was quarantined before he could live in England" Source: WordNet 2.0, 2003 Princeton University Source: On-line Medical Dictionary, 1997-98 Academic Medical Publishing & CancerWEB
Webby
> / > > [quoted text clipped - 27 lines] > > if we saw an increase of TB cases. Sorry I can'tt recall the name of the > > drug, but if I see it again I'll post it. W_B - 08 Nov 2005 19:33 GMT > AIDS is responsible for much of the TB outbreak >globally. AIDS is not even in the top 10 causes of death in the world. Last I checked it was ~#13. (WHO)
>I think its been reported that 5000 people die each day >(around the world) from TB. Find this hard to believe, can you cite a reference ?
Malaria is likely a cause of death resulting in such numbers.
Don't have time to research this, let me know what you find out. --
W_B Take out the G'RBAGE wubbabubbazG@RBAGEyahoo.com
The Webby - 11 Nov 2005 21:53 GMT > > AIDS is responsible for much of the TB outbreak > >globally. [quoted text clipped - 15 lines] > Take out the G'RBAGE > wubbabubbazG@RBAGEyahoo.com www.stoptb.org (WHO site)
Webby
The Webby - 13 Nov 2005 01:04 GMT In article <nospamattmjiatroepidemicnospam-376927.13535011112005@news-lb-01.socal.r r.com>,
> > > AIDS is responsible for much of the TB outbreak > > >globally. [quoted text clipped - 19 lines] > > Webby W_B, did you visit the website (www.stoptb.org)? Were your questions addressed adequately by the content?
TW
Mark & Steven Bornfeld - 08 Nov 2005 15:05 GMT >>> And it is amazing how quickly it was forgotten. It is only in this >>>generation that TB was mastered, yet nobody seems to remember the effect it [quoted text clipped - 18 lines] > > Vaughn I think Mark may even have written something about that somewhere on our website. That has to do with the fact that HIV disease has been legislated out of the "infectious disease" department and into the "disabling condition" department. There are ways to rationalize this--even ways that may seem to make a modicum of sense. But it's still intellectually dishonest and cynical.
Steve
 Signature Mark & Steven Bornfeld DDS http://www.dentaltwins.com Brooklyn, NY 718-258-5001
kureforcrohns@sbcglobal.net - 07 Nov 2005 15:00 GMT The Webby and Vaughn. Several parts of the posts from The Webby and Vaughn share incidences of which I am very aware. Though late, I must express sympathy to Vaughn for the plight of his mother and the impact it must have had on the children, even if subconsciously and curiosity as to who raised the children. Tuberculosis was indeed a dreaded disease. The tuberculosis facility in our area is now a senior complex with the old and newly built apartments. I share this because before any antibiotics my mother died young of an illness that today would be nothing. A mastoid ear infection. Cannot recall ever seeing her face. and other unrelated images come to mind. Read a book about the Roosevelts, and seeing a picture of Franklin Delano Roosevelt as a young, tall and athletic man, and being crippled by polio, is hard to think that could happen. to a man so important to the world. The clear and meaningful way in which The Webby describes Dr. Albert Schatz and the discovery of Streptomycin is a tribute to all persons dedicated to the betterment of mankind. I am sure that the memory to be recognized by him will remain awesome. Is the book "The TMJ Iatroepidemic" the one you have written, I would love to read it. Your method of expressions are beyond my capabilities. You say the sword of technology is a two edged sword. So aptly does it describe what I feel about anti-depressants and stimulants. That has yet to be affirmed. Scientific or not, it is very real. It doesn't fall into the category of discovering a medication for cure Some things in life do not fit the conventional mode. and I do believe it is a factor in the possible failure of implants. Thank you for so meaningful a post. Gail Also, I think pain is best expressed in words. mild, bearable, severe. Always or occasionally. In what ways is a person incapacitated by the pain. Are some days spent lying down. What function of the body or mind does it impact on. etc.
> "The Webby" <nospamattmjiatroepidemicnospam@san.rr.com> wrote in message news:nospamattmjiatroepidemicnospam-D09CFB.21191206112005@news-lb-01.socal.r r.com...
> > http://www.guardian.co.uk/weekend/story/0,3605,823114,00.html > > [quoted text clipped - 27 lines] > > Vaughn Sue - 07 Nov 2005 16:06 GMT TB- Yes, highly contagious. My dad 's sister died at 6 mo from bacterial meningitis (mycobacterium tuberculosis).
My grandma was walking her in a stroller. A neighbor lady who had been released from TB quarantine ... picked up the baby, cooed and aahhed... for some time.
Little did anyone know that she was still infectious. Within the next 2-3 weeks (I am not sure of the exact time frame, but soon thereafter), Maryanna (the baby) came down with high fever. She was diagnosed with tubercular meningitis. She died.
-Sue
Amatus Cremona - 07 Nov 2005 19:52 GMT > Little did anyone know that she was still infectious. Within the next > 2-3 weeks (I am not sure of the exact time frame, but soon thereafter), > Maryanna (the baby) came down with high fever. She was diagnosed with > tubercular meningitis. She died. As I watched Mimi die on stage of Consumption this past weekend. I could not help but think that the 4 other people in the apartment would be dead of it before year's end. Amazing how powerfully a lady can sing and then die of TB two minutes later.
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> TB- Yes, highly contagious. My dad 's sister died at 6 mo from > bacterial meningitis (mycobacterium tuberculosis). [quoted text clipped - 9 lines] > > -Sue Mark & Steven Bornfeld - 07 Nov 2005 20:02 GMT >>Little did anyone know that she was still infectious. Within the next >>2-3 weeks (I am not sure of the exact time frame, but soon thereafter), [quoted text clipped - 5 lines] > before year's end. Amazing how powerfully a lady can sing and then die of > TB two minutes later. Are you implying that Mimi is a fraud?
Steve
 Signature Mark & Steven Bornfeld DDS http://www.dentaltwins.com Brooklyn, NY 718-258-5001
W_B - 07 Nov 2005 21:18 GMT >> As I watched Mimi die on stage of Consumption this past weekend. I could not >> help but think that the 4 other people in the apartment would be dead of it [quoted text clipped - 4 lines] > >Steve I hear her new album is pretty good.
The Emancipation Of Mimi --
W_B Take out the G'RBAGE wubbabubbazG@RBAGEyahoo.com
Amatus Cremona - 08 Nov 2005 12:44 GMT > Are you implying that Mimi is a fraud? No fraud can sing high "C" like that and still manage to die moments later.
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> >>>Little did anyone know that she was still infectious. Within the next [quoted text clipped - 10 lines] > > Steve Mark & Steven Bornfeld - 08 Nov 2005 15:06 GMT >>Are you implying that Mimi is a fraud? > > No fraud can sing high "C" like that and still manage to die moments later. I think I'd need exceptionally tight underwear.
Steve
 Signature Mark & Steven Bornfeld DDS http://www.dentaltwins.com Brooklyn, NY 718-258-5001
Amatus Cremona - 08 Nov 2005 16:04 GMT > I think I'd need exceptionally tight underwear. Yeah, ladies do much better in tight underwear than we do.
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> >>>Are you implying that Mimi is a fraud? [quoted text clipped - 5 lines] > > Steve W_B - 08 Nov 2005 18:00 GMT >> Are you implying that Mimi is a fraud? > >No fraud can sing high "C" like that and still manage to die moments later. What is this all about ?
Who died on stage, what performance, etc... IOW what happened ? --
W_B Take out the G'RBAGE wubbabubbazG@RBAGEyahoo.com
W_B - 07 Nov 2005 20:51 GMT >> Little did anyone know that she was still infectious. Within the next >> 2-3 weeks (I am not sure of the exact time frame, but soon thereafter), [quoted text clipped - 5 lines] >before year's end. Amazing how powerfully a lady can sing and then die of >TB two minutes later. Whot ?!
I didn't hear of this, tell me more. --
W_B Take out the G'RBAGE wubbabubbazG@RBAGEyahoo.com
Amatus Cremona - 08 Nov 2005 12:47 GMT > I didn't hear of this, tell me more. Well, she broke Rodolfo's heart by dying. Worst of all, she died after he got up from her death bed and walked to the window in the hope that she was getting better.
Even Musetta's scream when she faked the twisted ankle was right on tone. Fabulous voices !
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> >>> Little did anyone know that she was still infectious. Within the next [quoted text clipped - 17 lines] > Take out the G'RBAGE > wubbabubbazG@RBAGEyahoo.com Mark & Steven Bornfeld - 08 Nov 2005 15:06 GMT >>I didn't hear of this, tell me more. > [quoted text clipped - 4 lines] > Even Musetta's scream when she faked the twisted ankle was right on tone. > Fabulous voices ! What opera company was this?
Steve
 Signature Mark & Steven Bornfeld DDS http://www.dentaltwins.com Brooklyn, NY 718-258-5001
The Webby - 08 Nov 2005 15:15 GMT > > I didn't hear of this, tell me more. > [quoted text clipped - 4 lines] > Even Musetta's scream when she faked the twisted ankle was right on tone. > Fabulous voices ! Which color cummerbund did you select?
TW
> / > > [quoted text clipped - 18 lines] > > Take out the G'RBAGE > > wubbabubbazG@RBAGEyahoo.com Amatus Cremona - 08 Nov 2005 16:09 GMT > Which color cummerbund did you select? I actually chose a gray checked vest with matching tie for my tuxedo that night. Mrs. Amatus had a fuchsia gown (with black lower half and semi-lace below the knees) which kept reminding our friends of the outfit Musetta had on--same color . I don't know how good it is having everyone compare your wife to a big flirt. At least Musetta seems to change her ways in the last act.
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> >> > I didn't hear of this, tell me more. [quoted text clipped - 43 lines] >> > Take out the G'RBAGE >> > wubbabubbazG@RBAGEyahoo.com W_B - 08 Nov 2005 19:28 GMT >> Even Musetta's scream when she faked the twisted ankle was right on tone. >> Fabulous voices ! > >Which color cummerbund did you select? > >TW The pink one with the candy stripe. --
W_B Take out the G'RBAGE wubbabubbazG@RBAGEyahoo.com
Amatus Cremona - 08 Nov 2005 19:29 GMT > The pink one with the candy stripe. Shhhhh !
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> >>> Even Musetta's scream when she faked the twisted ankle was right on [quoted text clipped - 11 lines] > Take out the G'RBAGE > wubbabubbazG@RBAGEyahoo.com W_B - 08 Nov 2005 18:01 GMT >> I didn't hear of this, tell me more. > [quoted text clipped - 4 lines] >Even Musetta's scream when she faked the twisted ankle was right on tone. >Fabulous voices ! Ok, so this is the story in the opera right ?
Mimi didn't really die, it was acting. --
W_B Take out the G'RBAGE wubbabubbazG@RBAGEyahoo.com
Amatus Cremona - 08 Nov 2005 19:28 GMT > Ok, so this is the story in the opera right ? > > Mimi didn't really die, it was acting. She looked pretty happy taking her bows after the curtain came down. Matter of fact, she took 3-4 bows. Well deserved.
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> >>> I didn't hear of this, tell me more. [quoted text clipped - 15 lines] > Take out the G'RBAGE > wubbabubbazG@RBAGEyahoo.com Vaughn - 07 Nov 2005 23:31 GMT > The Webby and Vaughn. > Several parts of the posts from The Webby and Vaughn share incidences of > which I am very aware. Though late, I must express sympathy to Vaughn > for the plight of his mother and the impact it must have had on the > children, Can't speak for the others, but I modestly think that I turned out OK.
>even if subconsciously and curiosity as to who raised the > children. Our father of course.
In the years when she was in the sanatorium, Dad apparently enjoyed somewhat better access to my mother than was allowed us kids. My youngest brother was (apparently) concieved and ultimately delivered there.
Vaughn
Sue - 08 Nov 2005 00:13 GMT In the years when she was in the sanatorium, Dad apparently enjoyed somewhat better access to my mother than was allowed us kids. My youngest brother was (apparently) concieved and ultimately delivered there.
Vaughn
Reply. That is a very interesting childhood. I am really sorry that you did not have contact with your mom growing up. How did your dad and brother avoid getting TB? Are you sure is was not you that was brought up in a sanatorium whiel the rest were cozy at home? Your story sounds pretty lame; at the very least, fradulent.
And to all the smart-mouths, my story is true about my grandma's baby girl. She was hospitalized and she died. I do not know the exact time-frame.
Oh whatever... you buncha music-men...
mi mi mi mi mi... GARY Indiana, Gary Indiana, Gary Indiana... loo, loo, loo, loo, la, la. I do not believe a word you say... la ,la, la, mi, mi, mi....
Sue
Sue - 08 Nov 2005 00:33 GMT And if it is all true, then I am really sorry.
I believe Gail but not so much some of the others. The others never seem serious.. so...?.
Gail I am sorry about your mom too. My mom died unexpectedly from an asthma attack, but I was not without a mom growing up.
My dad would have had to hire someone to take care of us if she had died while we were young, because he was on the road 75% of the time.
I cannot imagine what it would be like without a mom growing up.
She was always there for us.. except for a few times when she could not take the stress any longer and checked into a hotel... or jumped in her camper trailer and took off for the north woods.
But that was only a couple times.
Take Care, Sue
Vaughn - 08 Nov 2005 01:05 GMT > And if it is all true, then I am really sorry. Too late...go away.
Vaughn
carabelli - 08 Nov 2005 02:51 GMT >> And if it is all true, then I am really sorry. > > Too late...go away. > > Vaughn Avon calling
carabelli
W_B - 08 Nov 2005 17:10 GMT >>> And if it is all true, then I am really sorry. >> [quoted text clipped - 5 lines] > >carabelli How about a free copy of "The Watchtower" ? --
W_B Take out the G'RBAGE wubbabubbazG@RBAGEyahoo.com
W_B - 08 Nov 2005 17:00 GMT >> And if it is all true, then I am really sorry. > > Too late...go away. > >Vaughn Sue is off of her meds again, so it seems.
What a dork.
Moratorium for me too.
--
W_B Take out the G'RBAGE wubbabubbazG@RBAGEyahoo.com
kureforcrohns@sbcglobal.net - 08 Nov 2005 05:58 GMT > I cannot imagine what it would be like without a mom growing up. > >Without turning this thread to be a "A story of One's Life" I appreciate your statement as most people do not have that much insight. They think they are self-made.
> And I thank Vaughn for sharing. Gail
Vaughn - 08 Nov 2005 01:02 GMT > In the years when she was in the sanatorium, Dad apparently enjoyed > somewhat better access to my mother than was allowed us kids. My [quoted text clipped - 21 lines] > > Sue Vaughn - 08 Nov 2005 01:03 GMT > Your story sounds pretty lame; at the very least, fradulent. I don't know where the hell you came from, but please go back <plonk>
Vaughn
Amatus Cremona - 08 Nov 2005 12:43 GMT > I don't know where the hell you came from, but please go back <plonk> She has that effect on people, I have noticed it.
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> >> Your story sounds pretty lame; at the very least, fradulent. > > I don't know where the hell you came from, but please go back <plonk> > > Vaughn Dartos - 08 Nov 2005 14:26 GMT >>I don't know where the hell you came from, but please go back <plonk> > > She has that effect on people, I have noticed it. She probably doesn't believe that you came over here on a boat or that I started out on a farm in the middle of nowhere without running water or a TV.
I don't notice that it is too difficult to tell the jokes from the serious posts. If I happen to be in doubt, I just let it slide.
Dartos
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