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Medical Forum / General / Dentistry / October 2005

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grow new teeth practically possible?

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Hans - 23 Sep 2005 15:34 GMT
Hello,

This company is doing research on growing new teeth

http://www.odontis.co.uk/

How long do you think it will take before this becomes reality in dentist
practice?

How can you get an engineered tooth to grow into the jawbone?
CWatters - 23 Sep 2005 17:17 GMT
> How can you get an engineered tooth to grow into the jawbone?

and how do you stop it growing when it's the right size?
Stovepipe - 25 Sep 2005 03:07 GMT
>  >
> > How can you get an engineered tooth to grow into the jawbone?
>
> and how do you stop it growing when it's the right size?

.... and how many giga-Volts will it generate?

... and if it _does_ generate them, will the ensuing magnetic field
force two people, who happen to face each other on the tram, who have
front teeth growin' in their mugs, to crash into each others' faces due
to the overwhelming electromagnetic attractive force?

... and will they be able to drink liquids without frazzzing themselves?

... and if they go swimming, will every jellyfish in Odin's creation
seek them out in a love embrace?

Just wonderin'

SP
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Hans - 25 Sep 2005 12:49 GMT
Yes that's all possible if you take some more LSD.

> >  >
> > > How can you get an engineered tooth to grow into the jawbone?
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> --
> Take out the TRASH to reply
Joel M. Eichen - 25 Sep 2005 13:16 GMT
>Yes that's all possible if you take some more LSD.
>>
>> >  >
>> > > How can you get an engineered tooth to grow into the jawbone?
>> >
>> > and how do you stop it growing when it's the right size?

REPLY

Actually this is a huge problem. I saw this in a Woody Allen movie.
The tooth became huge and they had to call out a team of dentists to
drill out some space for a living room and a family room.

How did they finish the walls? Composite board of course.

Joel

>> .... and how many giga-Volts will it generate?
>>
[quoted text clipped - 13 lines]
>> --
>> Take out the TRASH to reply
Sue - 23 Sep 2005 23:29 GMT
Hans,

Have you heard of bone morphorgenic protein (BMP)?

We are currently using it in spinal surgery.

Sue (Medtronic)
Alexander Vasserman DDS - 24 Sep 2005 09:09 GMT
It has already been done at USC in vitro.

It involves using stem cells and a callogen scafolding shaped like a
tooth.
a tooth grows in this scafolding and can then be implanted in the
patient.
a crown will be required in the end.
This growing of teeth has not yet been packaged for private practice.
We are looking at another 10-15 years before it is ready for patients.

> Hello,
>
[quoted text clipped - 6 lines]
>
> How can you get an engineered tooth to grow into the jawbone?
Stovepipe - 25 Sep 2005 03:07 GMT
> It has already been done at USC in vitro.
>
[quoted text clipped - 5 lines]
> This growing of teeth has not yet been packaged for private practice.
> We are looking at another 10-15 years before it is ready for patients.

I have some other parts I wanna see grow... well at least one.... and
maybe some antennae...

SP
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Hans - 25 Sep 2005 12:50 GMT
I wonder what you need?

> > It has already been done at USC in vitro.
> >
[quoted text clipped - 12 lines]
> --
> Take out the TRASH to reply
Stovepipe - 25 Sep 2005 18:22 GMT
> > > It has already been done at USC in vitro.
> > >
[quoted text clipped - 12 lines]
> > --
> > Take out the TRASH to reply

> I wonder what you need?

..... This ain't the right forum fer that....

SP
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kureforcrohns@sbcglobal.net - 25 Sep 2005 17:36 GMT
Looking over old articles on dental possibilities for the future, this one
dated Dec 80, is titled "Serum to prevent tooth decay expected in 5 years".
Has it been overlooked by this consumer or like many predictions, never
materialized?     Short excerpts of the article.
A Federally sponsored program to produce vaccines against tooth decay is so
successful that immunization to prevent cavities can be expected in 5 to 10
years, the chief of the program said.
(Dr. William H. Bowen , chief of the caries prevention research branch of
the National Institute for Dental Research.)   Several types of vaccines are
being developed at research centers and trials in children are expected in
several years if  the vaccines continue to be proven safe , he said.
This would have a major impact on the nations oral health  and in dentistry.
Tooth decay is second only to colds as the most common affliction in the
country.   America's dental bill for treating cavities is 6 billion
annually.
One of the vaccines  made killed bacteria encased in capsules which are
swallowed.
etc. etc. etc.   Not even worth continuing.     Had to retrieve the article
from the garbage to quote it.
Names mentioned.
Dr. Bowen of the Royal College of Surgeons in London.
University of Alabama
State University of New York at Buffalo
Five monkey were injected with live bacteria.  In five years the monkeys
developed no cavities.    Lactic acid eats at tooth enamel causing cavities.

Has something been missed by consumers.
Gail
With such predictions, beginning to think my theory on the cause of crohns
may still have a chance.    The cost of research for crohns and loss of
productivity is 8 billion.
CWatters - 25 Sep 2005 19:06 GMT
> Looking over old articles on dental possibilities for the future, this one
> dated Dec 80, is titled "Serum to prevent tooth decay expected in 5 years".
> Has it been overlooked by this consumer or like many predictions, never
> materialized?

1998 - Scientists develop vaccine against tooth decay
The company hopes they can roll out a consumer product in 2001 or 2002
http://www.cnn.com/HEALTH/9804/29/tooth.decay/

http://www.markarkleiman.com/archives/microeconomics_and_policy_analysis_/2005/0
4/a_vaccine_against_tooth_decay.php

Quote: According to an NIH panel report, this is not work likely to be
funded by the pharmaceutical industry; the best time to do the immunization
is before teething, which means that the clinical trials to determine
whether the vaccine prevented caries in adults might last longer than the
patents.
Steven Bornfeld - 25 Sep 2005 21:40 GMT
> Looking over old articles on dental possibilities for the future, this one
> dated Dec 80, is titled "Serum to prevent tooth decay expected in 5 years".
[quoted text clipped - 27 lines]
> may still have a chance.    The cost of research for crohns and loss of
> productivity is 8 billion.

    Every couple of years a story about a caries vaccine floats about.
Most of those I've heard of come from the UK.  As long ago as my college
days (say, 1972 when I had decided to go to dental school) a dentist
speaking to us opined that the future didn't look too bright with a
caries vaccine in animal testing.
    What I had heard (perhaps not about that particular vaccine, is that
there was cross-sensitization with myocardium.  In English, that means
you develop an immune reaction to the bacteria responsible for caries
(S. mutans) AND a bonus immunity to heart muscle.  I'm guessing some
dentist planted that rumor.

Steve

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Stovepipe - 01 Oct 2005 20:26 GMT
>       Every couple of years a story about a caries vaccine floats about.
> Most of those I've heard of come from the UK.  As long ago as my college
[quoted text clipped - 8 lines]
>
> Steve

There _is_ enormous amounts of research being done to perfect the caries
vaccine. One of the Profs at U.Laval is in that group and they are
saying that it is really advancing by giant steps.

I'm lookin' for the company that comes out with it first and I'm bettin'
the farm on 'em when they make an IPO. If they give it to one of the
existing pharmacueuticals, I'm not bettin' a penny.

So sayeth the Pipe, back on the iBook with the Ethernet connection
plugged into it, because the @#$%?& rooter ain't workin' properly yet...

SP
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