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Medical Forum / General / Dentistry / March 2005

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question regarding enamel creation

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MAGIC5227@gmail.com - 24 Mar 2005 02:06 GMT
I was wondering how it is that enamel is created when a child is being
formed.  Is there no way to reproduce this process to add enamel to
teeth?  I dont understand how it can't be added if it's created
somehow, or is the process simply too difficult?
W_B - 24 Mar 2005 02:13 GMT
>I was wondering how it is that enamel is created when a child is being
>formed.  Is there no way to reproduce this process to add enamel to
>teeth?  I dont understand how it can't be added if it's created
>somehow, or is the process simply too difficult?

First you need some ameloblasts.

I doubt very much that you would find any donors.

--
W_B

wubbabubbazG@RBAGEyahoo.com
Take out the G'RBAGE
Joel M. Eichen - 24 Mar 2005 10:25 GMT
>>I was wondering how it is that enamel is created when a child is being
>>formed.  Is there no way to reproduce this process to add enamel to
[quoted text clipped - 4 lines]
>
>I doubt very much that you would find any donors.

...and Schein does not sell them .... YET!
Joel M. Eichen - 24 Mar 2005 10:25 GMT
>I was wondering how it is that enamel is created when a child is being
>formed.

Oh that's the amazing thing about life! The same applies to say, a
liver. How does that one cell ever develop into something known as a
liver?

The mysteries of life ....... that should be enough for any of us to
ponder once in a while .....

Joel

>  Is there no way to reproduce this process to add enamel to
>teeth?  I dont understand how it can't be added if it's created
>somehow, or is the process simply too difficult?

Too difficult for us 21st century mortals!
Mark & Steven Bornfeld - 24 Mar 2005 15:39 GMT
> I was wondering how it is that enamel is created when a child is being
> formed.  Is there no way to reproduce this process to add enamel to
> teeth?  I dont understand how it can't be added if it's created
> somehow, or is the process simply too difficult?

    The cells that form the enamel are lost when the tooth erupts.  The
cells that form the dentin however wind up lining the periphery of the
pulp in the center of the tooth.  If stimulated, they can create more
(secondary) dentin throughout the life of the nerve.

Steve

Signature

Mark & Steven Bornfeld DDS
http://www.dentaltwins.com
Brooklyn, NY
718-258-5001

MAGIC5227@gmail.com - 24 Mar 2005 22:33 GMT
Is there any way, potentially, to use stem cells to create these
ameloblasts for use in creating enamel?
Dr Steve - 24 Mar 2005 22:39 GMT
Enamel has to form before any of the rest of the tooth does.  Stem cell
research is under way to grow an entire tooth bud, but that is decades away
from real use.  If ever.

Signature

~+--~+--~+--~+--~+--
Stephen Mancuso, D.D.S.
Troy, Michigan, USA
....................................................

This posting is intended for informational or conversational purposes only.
Always seek the opinion of a licensed dental professional before acting on
the advice or opinion expressed here.  Only a dentist who has examined you
in person can diagnose your problems and make decisions which will affect
your health.
......................

> Is there any way, potentially, to use stem cells to create these
> ameloblasts for use in creating enamel?
Mark & Steven Bornfeld - 24 Mar 2005 23:04 GMT
> Is there any way, potentially, to use stem cells to create these
> ameloblasts for use in creating enamel?

    Hey--anything's possible.  My guess is that they'll try for treatments
for Parkinsons's d. or try for beta-islet pancreatic cells first.  But
hey--why not?
    As Dr. Steve alluded to, the formation of enamel has to be within the
framework of a functioning organ (tooth bud) to create a functioning
tooth.  I don't think you're going to sprinkle ameloblasts on tooth
enamel and create new enamel.
    The embryology of the tooth is actually quite fascinating.

Steve

Signature

Mark & Steven Bornfeld DDS
http://www.dentaltwins.com
Brooklyn, NY
718-258-5001

Joel M. Eichen - 24 Mar 2005 23:27 GMT
>Is there any way, potentially, to use stem cells to create these
>ameloblasts for use in creating enamel?

You might want to ask Jan if she can put in a good word with The Big
Guy ........ she is on first-name basis with Him.
W_B - 25 Mar 2005 00:09 GMT
>Is there any way, potentially, to use stem cells to create these
>ameloblasts for use in creating enamel?

Who knows.

Go get yourself a research grant.
--

W_B
Take out the G'RBAGE
wubbabubbazG@RBAGEyahoo.com
 
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