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Medical Forum / General / Dentistry / February 2005

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Osteo Necrotic Jaws ... (?)

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Joel M. Eichen - 06 Feb 2005 00:39 GMT
If you mean NICO, there is absolutely no record of that disease on Pub
Med, the Natrional Library of Medicine! Do we accept the word of
established researchers, or do we accept the word of alternative,
quack, money-grubbing practitioners?

Joel M. Eichen DDS

Sarah's Email <ser46@cox.net> wrote:
Dear Doctor,



Your posts about Osteo necrotic jaws, are very disturbing to a patient
who has suffered chronic OM in my mandible for 17months now! Here “we”
are, sick as dogs, and you dentists make jokes and act like children.
I am a 58yr old grandmother, and am a medical care giver, as a
Physical Therapist, and I’ve never read such disrespectful attitudes
toward a group of people who are ill, and hurting!



My husband also has Prostate Cancer, and on our support forum alone,
we have had three men who have contracted ONJ due to taking
bisphosphonates, and having dental procedures during their treatments.
Treatmentes aimed at keeping them from getting osteoporosis while on
Hormone therapy. World renowned prostate researcher and oncologist,
Dr. “Snuffy” Myers has warned all of his patients, that while taking
Fosamax, or other brands of bishphosphonates, they should NOT have any
dental surgery, or invasive dental treatments!  WE are not amused with
the lack of help, knowledge, and zero research being done by the ADA
to help patients with ONJ/ Osteo Necrotic Jaws!!



Sadly,

Sarah Raber

NW Arkansas

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Joel M. Eichen - 06 Feb 2005 00:43 GMT
What do you guys suggest we do?

Make up diseases and treat you for same, just so you will be
h-a-a-a-a-p-p-p-p-y?

Sounds like redecorating the family room, not anything to do with
dentistry!

Joel

>If you mean NICO, there is absolutely no record of that disease on Pub
>Med, the National Library of Medicine! Do we accept the word of
[quoted text clipped - 29 lines]
>
>NW Arkansas
clintonz@prodigy.net - 06 Feb 2005 03:43 GMT
> What do you guys suggest we do?
>
[quoted text clipped - 5 lines]
>
> Joel

Where is J Boquot?

Jawbone cavities and trigeminal and atypical facial neuralgias.

Ratner EJ, Person P, Kleinman DJ, Shklar G, Socransky SS.

Oral Surg Oral Med Oral Pathol 1979 Jul;48(1):3-20

http://www.ncbi.nlm.nih.gov/entrez/PubMed&list_uids=287984&dopt=Abstract

The possible role of dental and oral disease in the etiology of
idiopathic trigeminal and atypical facial neuralgias has been examined.

Among thirty-eight patients with idiopathic trigeminal neuralgia and
twenty-three patients with atypical facial neuralgia, there was in
nearly all instances a close relationship between pain experienced and
the existence of cavities in alveolar bone and jawbone of the patients.

The cavities were at the sites of previous tooth extractions and,
although at times more than 1 cm. in a given diameter, were usually not

detectable by x-rays. A new method for their detection and localization

was developed empirically, based on the observation that peripheral
infiltration of local anesthetic into or very close to the bone cavity
rapidly abolished trigger and pain perception by patients during
persistence of the anesthetic action. Histopathologic examination of
bone removed from cavities by curettage revealed, in both idiopathic
trigeminal and atypical facial neuralgias, a similar pattern
characterized by a highly vascular abnormal healing response of bone.
Some lesions presented a mild chronic inflammatory (lymphocytic)
infiltration. Preliminary microbiologic studies of material from the
walls of the cavities showed the existence within them of a complex,
mixed polymicrobial aerobic and anaerobic flora. Treatment consisted of

vigorous curettage of the bone cavities, repeated if necessary, plus
administration of antibiotics to induce healing and filling-in of the
cavities by new bone. Responses of patients to the above treatment
consisted of marked to complete pain remissions, the longest of which
has been for 9 years. Complete healing leads to complete and persistent

pain remissions. It was concluded that in both idiopathic trigeminal
and atypical facial neuralgias, dental and oral pathoses may be major
etiologic factors.

I'd be very interested to hear your scientific respone to this
Joel M. Eichen - 06 Feb 2005 13:27 GMT
>> What do you guys suggest we do?
>>
[quoted text clipped - 7 lines]
>
>Where is J Boquot?

West Virginny.

Another guy is Kularz who is in Mt. Kisco, New York.

Joel

>Jawbone cavities and trigeminal and atypical facial neuralgias.
>
[quoted text clipped - 40 lines]
>
>I'd be very interested to hear your scientific respone to this
clintonz@prodigy.net - 06 Feb 2005 18:12 GMT
> >> What do you guys suggest we do?
> >>
[quoted text clipped - 11 lines]
>
> Another guy is Kularz who is in Mt. Kisco, New York.

On the study I posted. I thought you said they were
all done by JB. I'm beginning to understand how the
dental establishment works. They don't look for stuff
then say there is no proof its there. But they've been
at this since 1979?!
Joel M. Eichen - 06 Feb 2005 19:01 GMT
>> >> What do you guys suggest we do?
>> >>
[quoted text clipped - 17 lines]
>then say there is no proof its there. But they've been
>at this since 1979?!

Bouquot is the only researcher who publishes papers. Kularz as far as
I know has not published anything.

Check the publications and you will see no double-blind studies.

Its all observational.

This is like describing crop patterns attributed to aliens. I do not
mean from the Former Soviet Union, I mean interplanetary aliens.

Joel
clintonz@prodigy.net - 06 Feb 2005 19:30 GMT
1 cm area of mixed polymicrobial flora. I get it, If you observe
something not
sanctioned by the economic interestes of the ADA it can't be so?

I guess a plant could grow up through your nose, but  LOW and behold
the ADA sayeth it can't be!

Who the heck is going to do jaw surgery on someone who may not have
this condition, or not do surgery on someone who does have infection?

Yeah, your jaw is infected and it MAY be causing you pain, but we can't
tell you if we are actually going to do surgery or just drill into your
jaw
for the fun of it because your response may be psychosomatic.

NOte the existence of what the authors call cavitations or do you think
they fooled themselves into imaging those. BE CAREFUL they got
pictures..

On the other hand where are the studies done to rule out the condition.
Let's see any studies done on it.
Joel M. Eichen - 06 Feb 2005 20:38 GMT
>1 cm area of mixed polymicrobial flora. I get it, If you observe
>something not
>sanctioned by the economic interestes of the ADA it can't be so?

a.k.a. Ye Goode Olde Boye and Girle Clubbe ... according to the
Janster.

Joel

>I guess a plant could grow up through your nose, but  LOW and behold
>the ADA sayeth it can't be!

Yup, the ADA sayeth it cannoteth beeth.

>Who the heck is going to do jaw surgery on someone who may not have
>this condition, or not do surgery on someone who does have infection?
[quoted text clipped - 10 lines]
>On the other hand where are the studies done to rule out the condition.
>Let's see any studies done on it.
MC60614 - 07 Feb 2005 02:55 GMT
Hey Joel, I will take several room makeovers if you got em. I need a partial
because of tooth lose from Vanna Whites tooth witening junk and two new
permanant teeth and a crown.. I want everything porcelein vennered and i need
it for free. Expert work only please...MC
Joel M. Eichen - 07 Feb 2005 13:44 GMT
>Hey Joel, I will take several room makeovers if you got em. I need a partial
>because of tooth lose from Vanna Whites tooth witening junk and two new
>permanant teeth and a crown.. I want everything porcelein vennered and i need
>it for free. Expert work only please...MC

You got it!
Joel M. Eichen - 06 Feb 2005 00:46 GMT
Six studies ,,, all from Jerry Bouquot!

Joel

1:  Adams WR, Spolnik KJ, Bouquot JE. Related Articles, Links  
Maxillofacial osteonecrosis in a patient with multiple "idiopathic"
facial pains.
J Oral Pathol Med. 1999 Oct;28(9):423-32.
PMID: 10535367 [PubMed - indexed for MEDLINE]
2:  Glueck CJ, McMahon RE, Bouquot JE, Triplett D, Gruppo R, Wang P.
Related Articles, Links  
Heterozygosity for the Leiden mutation of the factor V gene, a common
pathoetiology for osteonecrosis of the jaw, with thrombophilia
augmented by exogenous estrogens.
J Lab Clin Med. 1997 Nov;130(5):540-3.
PMID: 9390643 [PubMed - indexed for MEDLINE]
3:  Gruppo R, Glueck CJ, McMahon RE, Bouquot J, Rabinovich BA, Becker
A, Tracy T, Wang P. Related Articles, Links  
The pathophysiology of alveolar osteonecrosis of the jaw:
anticardiolipin antibodies, thrombophilia, and hypofibrinolysis.
J Lab Clin Med. 1996 May;127(5):481-8.
PMID: 8621985 [PubMed - indexed for MEDLINE]
4:  Bouquot JE, Christian J. Related Articles, Links  
Long-term effects of jawbone curettage on the pain of facial
neuralgia.
J Oral Maxillofac Surg. 1995 Apr;53(4):387-97; discussion 397-9.
PMID: 7699492 [PubMed - indexed for MEDLINE]
5:  Bouquot JE. Related Articles, Links  
Ischemia and infarction of the jaws--the "phantom" pain of NICO.
Cranio. 1994 Jul;12(3):138-9. No abstract available.
PMID: 7813023 [PubMed - indexed for MEDLINE]
6:  Bouquot JE, Roberts AM, Person P, Christian J. Related Articles,
Links  
Neuralgia-inducing cavitational osteonecrosis (NICO). Osteomyelitis
in 224 jawbone samples from patients with facial neuralgia.
Oral Surg Oral Med Oral Pathol. 1992 Mar;73(3):307-19; discussion
319-20. Review.
PMID: 1545963 [PubMed - indexed for MEDLINE]

**

>If you mean NICO, there is absolutely no record of that disease on Pub
>Med, the Natrional Library of Medicine! Do we accept the word of
[quoted text clipped - 29 lines]
>
>NW Arkansas
Joel M. Eichen - 06 Feb 2005 00:47 GMT
This study thirteen years ago!

**

Joel

**

Oral Surg Oral Med Oral Pathol. 1992 Mar;73(3):307-19; discussion
319-20. Related Articles, Links  

Comment in:
Oral Surg Oral Med Oral Pathol. 1992 Sep;74(3):348-50.

Neuralgia-inducing cavitational osteonecrosis (NICO). Osteomyelitis in
224 jawbone samples from patients with facial neuralgia.

Bouquot JE, Roberts AM, Person P, Christian J.

Department of Oral Surgery, West Virginia University School of
Dentistry.

A somewhat obscure etiologic theory for facial neuralgias presumes a
low-grade osteomyelitis of the jaws that produces neural degeneration
with subsequent production of inappropriate pain signals. Animal
investigations and treatment successes with human patients based on
this theory lend it credence. The present study examined 224 tissue
samples removed from alveolar bone cavities in 135 patients with
trigeminal neuralgia or atypical facial neuralgia. All tissue samples
demonstrated clear evidence of chronic intraosseous inflammation. The
most common microscopic features included dense marrow fibrosis or
"scar" formation, a sprinkling of lymphocytes in a relative absence of
other inflammatory cells (especially histiocytes), and smudged,
nonresorbing necrotic bone flakes. Very little healing or new bone
formation was visible. These lesions were able to burrow several
centimeters to initiate distant cavities. The present preliminary
investigation cannot prove etiology, but the presence of intraosseous
inflammation in every single jawbone specimen in these patients and
certain clinical and treatment aspects of these lesions (to be
reported later) has led the authors to recommend the term
neuralgia-inducing cavitational osteonecrosis or NICO for these
lesions.

Publication Types:
Review
Review of Reported Cases

PMID: 1545963 [PubMed - indexed for MEDLINE]

**

>If you mean NICO, there is absolutely no record of that disease on Pub
>Med, the Natrional Library of Medicine! Do we accept the word of
[quoted text clipped - 29 lines]
>
>NW Arkansas
Joel M. Eichen - 06 Feb 2005 00:50 GMT
Of course, these conditions must be ruled out!

If the doctor is treating you without ruling out this etiology, he
needs to go back to dental school!

If he is treating symptoms, then he could be a real quacker.

Joel

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**

>If you mean NICO, there is absolutely no record of that disease on Pub
>Med, the Natrional Library of Medicine! Do we accept the word of
[quoted text clipped - 29 lines]
>
>NW Arkansas
Joel M. Eichen - 06 Feb 2005 13:36 GMT
Sarah replied,

"'Mr Joel Eichen'" <joeleichen@yahoo.com>
Subject: RE: Reading post on Dentist-forum.net
Date: Sat, 5 Feb 2005 19:04:26 -0600

   
NO, I am accepting the word of my local dentist, Dr. Adair, my oral
surgeon, Dr. Deatherage, my orthopedic doctor, Dr. Mertz, my ENT, Dr.
Mellon, and my Infectious Disease physician, Dr. Hennigan.  What are
YOU offering?



Sarah R.

>If you mean NICO, there is absolutely no record of that disease on Pub
>Med, the Natrional Library of Medicine! Do we accept the word of
[quoted text clipped - 29 lines]
>
>NW Arkansas
 
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