Medical Forum / General / Dentistry / February 2005
Osteo Necrotic Jaws ... (?)
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Joel M. Eichen - 06 Feb 2005 00:39 GMT If you mean NICO, there is absolutely no record of that disease on Pub Med, the Natrional Library of Medicine! Do we accept the word of established researchers, or do we accept the word of alternative, quack, money-grubbing practitioners?
Joel M. Eichen DDS
Sarah's Email <ser46@cox.net> wrote: Dear Doctor,
Your posts about Osteo necrotic jaws, are very disturbing to a patient who has suffered chronic OM in my mandible for 17months now! Here we are, sick as dogs, and you dentists make jokes and act like children. I am a 58yr old grandmother, and am a medical care giver, as a Physical Therapist, and Ive never read such disrespectful attitudes toward a group of people who are ill, and hurting!
My husband also has Prostate Cancer, and on our support forum alone, we have had three men who have contracted ONJ due to taking bisphosphonates, and having dental procedures during their treatments. Treatmentes aimed at keeping them from getting osteoporosis while on Hormone therapy. World renowned prostate researcher and oncologist, Dr. Snuffy Myers has warned all of his patients, that while taking Fosamax, or other brands of bishphosphonates, they should NOT have any dental surgery, or invasive dental treatments! WE are not amused with the lack of help, knowledge, and zero research being done by the ADA to help patients with ONJ/ Osteo Necrotic Jaws!!
Sadly,
Sarah Raber
NW Arkansas
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Joel M. Eichen - 06 Feb 2005 00:43 GMT What do you guys suggest we do?
Make up diseases and treat you for same, just so you will be h-a-a-a-a-p-p-p-p-y?
Sounds like redecorating the family room, not anything to do with dentistry!
Joel
>If you mean NICO, there is absolutely no record of that disease on Pub >Med, the National Library of Medicine! Do we accept the word of [quoted text clipped - 29 lines] > >NW Arkansas clintonz@prodigy.net - 06 Feb 2005 03:43 GMT > What do you guys suggest we do? > [quoted text clipped - 5 lines] > > Joel Where is J Boquot?
Jawbone cavities and trigeminal and atypical facial neuralgias.
Ratner EJ, Person P, Kleinman DJ, Shklar G, Socransky SS.
Oral Surg Oral Med Oral Pathol 1979 Jul;48(1):3-20
http://www.ncbi.nlm.nih.gov/entrez/PubMed&list_uids=287984&dopt=Abstract
The possible role of dental and oral disease in the etiology of idiopathic trigeminal and atypical facial neuralgias has been examined.
Among thirty-eight patients with idiopathic trigeminal neuralgia and twenty-three patients with atypical facial neuralgia, there was in nearly all instances a close relationship between pain experienced and the existence of cavities in alveolar bone and jawbone of the patients.
The cavities were at the sites of previous tooth extractions and, although at times more than 1 cm. in a given diameter, were usually not
detectable by x-rays. A new method for their detection and localization
was developed empirically, based on the observation that peripheral infiltration of local anesthetic into or very close to the bone cavity rapidly abolished trigger and pain perception by patients during persistence of the anesthetic action. Histopathologic examination of bone removed from cavities by curettage revealed, in both idiopathic trigeminal and atypical facial neuralgias, a similar pattern characterized by a highly vascular abnormal healing response of bone. Some lesions presented a mild chronic inflammatory (lymphocytic) infiltration. Preliminary microbiologic studies of material from the walls of the cavities showed the existence within them of a complex, mixed polymicrobial aerobic and anaerobic flora. Treatment consisted of
vigorous curettage of the bone cavities, repeated if necessary, plus administration of antibiotics to induce healing and filling-in of the cavities by new bone. Responses of patients to the above treatment consisted of marked to complete pain remissions, the longest of which has been for 9 years. Complete healing leads to complete and persistent
pain remissions. It was concluded that in both idiopathic trigeminal and atypical facial neuralgias, dental and oral pathoses may be major etiologic factors.
I'd be very interested to hear your scientific respone to this
Joel M. Eichen - 06 Feb 2005 13:27 GMT >> What do you guys suggest we do? >> [quoted text clipped - 7 lines] > >Where is J Boquot? West Virginny.
Another guy is Kularz who is in Mt. Kisco, New York.
Joel
>Jawbone cavities and trigeminal and atypical facial neuralgias. > [quoted text clipped - 40 lines] > >I'd be very interested to hear your scientific respone to this clintonz@prodigy.net - 06 Feb 2005 18:12 GMT > >> What do you guys suggest we do? > >> [quoted text clipped - 11 lines] > > Another guy is Kularz who is in Mt. Kisco, New York. On the study I posted. I thought you said they were all done by JB. I'm beginning to understand how the dental establishment works. They don't look for stuff then say there is no proof its there. But they've been at this since 1979?!
Joel M. Eichen - 06 Feb 2005 19:01 GMT >> >> What do you guys suggest we do? >> >> [quoted text clipped - 17 lines] >then say there is no proof its there. But they've been >at this since 1979?! Bouquot is the only researcher who publishes papers. Kularz as far as I know has not published anything.
Check the publications and you will see no double-blind studies.
Its all observational.
This is like describing crop patterns attributed to aliens. I do not mean from the Former Soviet Union, I mean interplanetary aliens.
Joel
clintonz@prodigy.net - 06 Feb 2005 19:30 GMT 1 cm area of mixed polymicrobial flora. I get it, If you observe something not sanctioned by the economic interestes of the ADA it can't be so?
I guess a plant could grow up through your nose, but LOW and behold the ADA sayeth it can't be!
Who the heck is going to do jaw surgery on someone who may not have this condition, or not do surgery on someone who does have infection?
Yeah, your jaw is infected and it MAY be causing you pain, but we can't tell you if we are actually going to do surgery or just drill into your jaw for the fun of it because your response may be psychosomatic.
NOte the existence of what the authors call cavitations or do you think they fooled themselves into imaging those. BE CAREFUL they got pictures..
On the other hand where are the studies done to rule out the condition. Let's see any studies done on it.
Joel M. Eichen - 06 Feb 2005 20:38 GMT >1 cm area of mixed polymicrobial flora. I get it, If you observe >something not >sanctioned by the economic interestes of the ADA it can't be so? a.k.a. Ye Goode Olde Boye and Girle Clubbe ... according to the Janster.
Joel
>I guess a plant could grow up through your nose, but LOW and behold >the ADA sayeth it can't be! Yup, the ADA sayeth it cannoteth beeth.
>Who the heck is going to do jaw surgery on someone who may not have >this condition, or not do surgery on someone who does have infection? [quoted text clipped - 10 lines] >On the other hand where are the studies done to rule out the condition. >Let's see any studies done on it. MC60614 - 07 Feb 2005 02:55 GMT Hey Joel, I will take several room makeovers if you got em. I need a partial because of tooth lose from Vanna Whites tooth witening junk and two new permanant teeth and a crown.. I want everything porcelein vennered and i need it for free. Expert work only please...MC
Joel M. Eichen - 07 Feb 2005 13:44 GMT >Hey Joel, I will take several room makeovers if you got em. I need a partial >because of tooth lose from Vanna Whites tooth witening junk and two new >permanant teeth and a crown.. I want everything porcelein vennered and i need >it for free. Expert work only please...MC You got it!
Joel M. Eichen - 06 Feb 2005 00:46 GMT Six studies ,,, all from Jerry Bouquot!
Joel
1: Adams WR, Spolnik KJ, Bouquot JE. Related Articles, Links Maxillofacial osteonecrosis in a patient with multiple "idiopathic" facial pains. J Oral Pathol Med. 1999 Oct;28(9):423-32. PMID: 10535367 [PubMed - indexed for MEDLINE] 2: Glueck CJ, McMahon RE, Bouquot JE, Triplett D, Gruppo R, Wang P. Related Articles, Links Heterozygosity for the Leiden mutation of the factor V gene, a common pathoetiology for osteonecrosis of the jaw, with thrombophilia augmented by exogenous estrogens. J Lab Clin Med. 1997 Nov;130(5):540-3. PMID: 9390643 [PubMed - indexed for MEDLINE] 3: Gruppo R, Glueck CJ, McMahon RE, Bouquot J, Rabinovich BA, Becker A, Tracy T, Wang P. Related Articles, Links The pathophysiology of alveolar osteonecrosis of the jaw: anticardiolipin antibodies, thrombophilia, and hypofibrinolysis. J Lab Clin Med. 1996 May;127(5):481-8. PMID: 8621985 [PubMed - indexed for MEDLINE] 4: Bouquot JE, Christian J. Related Articles, Links Long-term effects of jawbone curettage on the pain of facial neuralgia. J Oral Maxillofac Surg. 1995 Apr;53(4):387-97; discussion 397-9. PMID: 7699492 [PubMed - indexed for MEDLINE] 5: Bouquot JE. Related Articles, Links Ischemia and infarction of the jaws--the "phantom" pain of NICO. Cranio. 1994 Jul;12(3):138-9. No abstract available. PMID: 7813023 [PubMed - indexed for MEDLINE] 6: Bouquot JE, Roberts AM, Person P, Christian J. Related Articles, Links Neuralgia-inducing cavitational osteonecrosis (NICO). Osteomyelitis in 224 jawbone samples from patients with facial neuralgia. Oral Surg Oral Med Oral Pathol. 1992 Mar;73(3):307-19; discussion 319-20. Review. PMID: 1545963 [PubMed - indexed for MEDLINE]
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>If you mean NICO, there is absolutely no record of that disease on Pub >Med, the Natrional Library of Medicine! Do we accept the word of [quoted text clipped - 29 lines] > >NW Arkansas Joel M. Eichen - 06 Feb 2005 00:47 GMT This study thirteen years ago!
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Joel
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Oral Surg Oral Med Oral Pathol. 1992 Mar;73(3):307-19; discussion 319-20. Related Articles, Links
Comment in: Oral Surg Oral Med Oral Pathol. 1992 Sep;74(3):348-50.
Neuralgia-inducing cavitational osteonecrosis (NICO). Osteomyelitis in 224 jawbone samples from patients with facial neuralgia.
Bouquot JE, Roberts AM, Person P, Christian J.
Department of Oral Surgery, West Virginia University School of Dentistry.
A somewhat obscure etiologic theory for facial neuralgias presumes a low-grade osteomyelitis of the jaws that produces neural degeneration with subsequent production of inappropriate pain signals. Animal investigations and treatment successes with human patients based on this theory lend it credence. The present study examined 224 tissue samples removed from alveolar bone cavities in 135 patients with trigeminal neuralgia or atypical facial neuralgia. All tissue samples demonstrated clear evidence of chronic intraosseous inflammation. The most common microscopic features included dense marrow fibrosis or "scar" formation, a sprinkling of lymphocytes in a relative absence of other inflammatory cells (especially histiocytes), and smudged, nonresorbing necrotic bone flakes. Very little healing or new bone formation was visible. These lesions were able to burrow several centimeters to initiate distant cavities. The present preliminary investigation cannot prove etiology, but the presence of intraosseous inflammation in every single jawbone specimen in these patients and certain clinical and treatment aspects of these lesions (to be reported later) has led the authors to recommend the term neuralgia-inducing cavitational osteonecrosis or NICO for these lesions.
Publication Types: Review Review of Reported Cases
PMID: 1545963 [PubMed - indexed for MEDLINE]
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>If you mean NICO, there is absolutely no record of that disease on Pub >Med, the Natrional Library of Medicine! Do we accept the word of [quoted text clipped - 29 lines] > >NW Arkansas Joel M. Eichen - 06 Feb 2005 00:50 GMT Of course, these conditions must be ruled out!
If the doctor is treating you without ruling out this etiology, he needs to go back to dental school!
If he is treating symptoms, then he could be a real quacker.
Joel
Items 1 - 20 of 33 Next 1: Bagan JV, Murillo J, Jimenez Y, Poveda R, Milian MA, Sanchis JM, Silvestre FJ, Scully C. Related Articles, Links Avascular jaw osteonecrosis in association with cancer chemotherapy: series of 10 cases. J Oral Pathol Med. 2005 Feb;34(2):120-3. PMID: 15641993 [PubMed - in process] 2: Tanvetyanon T. Related Articles, Links Re: Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J Natl Cancer Inst. 2005 Jan 5;97(1):70; author reply 70-1. No abstract available. PMID: 15632382 [PubMed - indexed for MEDLINE] 3: Atanasov DT, Indjov SI, Lalabonova HK, Neichev DS. Related Articles, Links Sarcomas of the mandible. Literature review and case reports. Folia Med (Plovdiv). 2004;46(2):31-5. Review. PMID: 15506548 [PubMed - indexed for MEDLINE] 4: Lugassy G, Shaham R, Nemets A, Ben-Dor D, Nahlieli O. Related Articles, Links Severe osteomyelitis of the jaw in long-term survivors of multiple myeloma: a new clinical entity. Am J Med. 2004 Sep 15;117(6):440-1. No abstract available. PMID: 15380503 [PubMed - indexed for MEDLINE] 5: Carlson ER, Monteleone K. Related Articles, Links An analysis of inadvertent perforations of mucosa and skin concurrent with mandibular reconstruction. J Oral Maxillofac Surg. 2004 Sep;62(9):1103-7. PMID: 15346361 [PubMed - indexed for MEDLINE] 6: Tarner IH, Schneidewind A, Linde HJ, Schubert T, Scholmerich J, Gluck T, Muller-Ladner U. Related Articles, Links Maxillary actinomycosis in an immunocompromised patient with longstanding vasculitis treated with mycophenolate mofetil. J Rheumatol. 2004 Sep;31(9):1869-71. No abstract available. PMID: 15338517 [PubMed - indexed for MEDLINE] 7: Perez-Garcia S, Berini-Aytes L, Gay-Escoda C. Related Articles, Links Ossifying fibroma of the upper jaw: Report of a case and review of the literature. Med Oral. 2004 Aug-Oct;9(4):333-9. English, Spanish. PMID: 15292873 [PubMed - in process] 8: Harvey BR, Ephros H, Defalco RJ. Related Articles, Links Tetracycline bone labeling in surgical management of chronic osteomyelitis: a case report. J Oral Maxillofac Surg. 2004 Jun;62(6):752-4. No abstract available. PMID: 15170293 [PubMed - indexed for MEDLINE] 9: Feng BG. Related Articles, Links [Treatment of osteomyelitis of the jaw with hyperbaric oxgen] Shanghai Kou Qiang Yi Xue. 1997 Jun;6(2):109-10. Chinese. No abstract available. PMID: 15159947 [PubMed - in process] 10: Chaudhary S, Kalra N, Gomber S. Related Articles, Links Tuberculous osteomyelitis of the mandible: a case report in a 4-year-old child. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 May;97(5):603-6. PMID: 15153873 [PubMed - indexed for MEDLINE] 11: Loh FC, Ling SY. Related Articles, Links Acute osteomyelitis of the maxilla in the newborn. J Laryngol Otol. 1993 Jul;107(7):627-8. Review. PMID: 15125285 [PubMed - indexed for MEDLINE] 12: Ruggiero SL, Mehrotra B, Rosenberg TJ, Engroff SL. Related Articles, Links Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases. J Oral Maxillofac Surg. 2004 May;62(5):527-34. PMID: 15122554 [PubMed - indexed for MEDLINE] 13: Bilgili H, Kurum B. Related Articles, Links Treatment of fractures of the mandible and maxilla by mini titanium plate fixation systems in dogs and cats. Aust Vet J. 2003 Nov;81(11):671-3. PMID: 15086106 [PubMed - indexed for MEDLINE] 14: Hartley MP, Sanderson S. Related Articles, Links Use of antibiotic impregnated polymethylmethacrylate beads for the treatment of chronic mandibular osteomyelitis in a Bennett's wallaby (Macropus rufogriseus rufogriseus). Aust Vet J. 2003 Dec;81(12):742-4. PMID: 15080484 [PubMed - indexed for MEDLINE] 15: Song QG, Shi B, Huang X, Li S, Lu Y. Related Articles, Links [The influence to maxillary growth by exposed bone wound in hard palate of rat] Hua Xi Kou Qiang Yi Xue Za Zhi. 2004 Feb;22(1):13-5. Chinese. PMID: 15017689 [PubMed - indexed for MEDLINE] 16: de Jong B, Vander Poorten V, Smet M, Hermans R, Proesmans M, De Boeck K. Related Articles, Links A 1-year old girl with fever and a unilateral swelling of the jaw. Eur J Pediatr. 2004 Mar;163(3):179-80. Epub 2004 Jan 29. No abstract available. PMID: 14749926 [PubMed - indexed for MEDLINE] 17: Baltensperger M, Gratz K, Bruder E, Lebeda R, Makek M, Eyrich G. Related Articles, Links Is primary chronic osteomyelitis a uniform disease? Proposal of a classification based on a retrospective analysis of patients treated in the past 30 years. J Craniomaxillofac Surg. 2004 Feb;32(1):43-50. Review. PMID: 14729050 [PubMed - indexed for MEDLINE] 18: Rizzardi C, Maglione M, Tirelli G, Frezzini C, Melato M. Related Articles, Links Pathologic quiz case: a 70-year-old woman with an expansile lesion of the right anterior mandible. Periapical cemento-osseous dysplasia with superimposed chronic osteomyelitis. Arch Pathol Lab Med. 2003 Nov;127(11):e427-9. No abstract available. PMID: 14567735 [PubMed - indexed for MEDLINE] 19: Lee K, Kaneda T, Mori S, Minami M, Motohashi J, Yamashiro M. Related Articles, Links Magnetic resonance imaging of normal and osteomyelitis in the mandible: assessment of short inversion time inversion recovery sequence. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003 Oct;96(4):499-507. PMID: 14561978 [PubMed - indexed for MEDLINE] 20: Paim LB, Liphaus BL, Rocha AC, Castellanos AL, Silva CA. Related Articles, Links [Chronic recurrent multifocal osteomyelitis of the mandible: report of three cases] J Pediatr (Rio J). 2003 Sep-Oct;79(5):467-70. Portuguese. 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>If you mean NICO, there is absolutely no record of that disease on Pub >Med, the Natrional Library of Medicine! Do we accept the word of [quoted text clipped - 29 lines] > >NW Arkansas Joel M. Eichen - 06 Feb 2005 13:36 GMT Sarah replied,
"'Mr Joel Eichen'" <joeleichen@yahoo.com> Subject: RE: Reading post on Dentist-forum.net Date: Sat, 5 Feb 2005 19:04:26 -0600
NO, I am accepting the word of my local dentist, Dr. Adair, my oral surgeon, Dr. Deatherage, my orthopedic doctor, Dr. Mertz, my ENT, Dr. Mellon, and my Infectious Disease physician, Dr. Hennigan. What are YOU offering?
Sarah R.
>If you mean NICO, there is absolutely no record of that disease on Pub >Med, the Natrional Library of Medicine! Do we accept the word of [quoted text clipped - 29 lines] > >NW Arkansas
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