Medical Forum / General / Dentistry / November 2005
Autoimmune disease and dental problems
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thedogzoo - 03 Feb 2005 23:51 GMT Hello.I was wondering if any of the dentists here know of any correlation between an autoimmune disease and dental problems?Despite having followed my dentist's advice most of my life, I am still facing dentures in the next month or so.I know that in the past I have been told that autoimmune diseases effect your healing time and can cause hypersensitivity to pain, but, can they actually encourage dental disease despite proper dental maintenance?
thedogzoo
Joel M. Eichen - 04 Feb 2005 00:34 GMT >Hello.I was wondering if any of the dentists here know of any >correlation between an autoimmune disease and dental problems? No there are none.
>Despite >having followed my dentist's advice most of my life, I am still facing [quoted text clipped - 4 lines] > >thedogzoo Advocate147 - 04 Feb 2005 00:55 GMT Dr. Joel,
I am amazed. All my words are down the drain. No question that an autoimmune disease can affect the teeth. especially if crohns or Ulcerative Colitis. These have to be the most misunderstood illnesses in recent times. Tony Bad sent some link awhile back showing the link of teeth problems to crohns. Can't find it for the moment, so maybe Tony will cite it again. I love you, but I have to differ with you. Maybe this will be the impetus for dentists to KNOW that oral problems can be caused by crohns as well as ANY OTHER problem that does not seem to be connected. Symptoms to crohns are subtle Not all, illness of course,belong to crohns. The majority are legitimate illnesses. But crohns is weird and acts like no other illness because it is a reaction to stimulants. As I have said before, a dentist only knows what he sees and cannot connect problems to crohns. Perhaps other oral problems are connected to legitimate illnesses such as Diabetes, etc. as was pointed out to me. and those can be recognized by the dentist. but crohns is another matter. As I said just today, it is subtle with unrecognizable symptoms belonging to crohns. More than ever, this illness should be known for what it is. (a disabling, stupid illness that pervades our society) Twice in one day, that is a record. Is there a better way to put it. Gail
Joel M. Eichen - 04 Feb 2005 01:20 GMT >Dr. Joel, > >I am amazed. All my words are down the drain. That's just my fast answer. It may be right, it may be wrong!
Joel
> No question that an >autoimmune disease can affect the teeth. especially if crohns or Ulcerative [quoted text clipped - 17 lines] >Is there a better way to put it. >Gail Joel M. Eichen - 04 Feb 2005 01:21 GMT >Dr. Joel, > [quoted text clipped - 7 lines] >caused by crohns as well as ANY OTHER problem that does not seem to be >connected. I had enough trouble keeping up with the newfangled tooth carpentry stuff so I left Crohn's to the medical men.
Joel
> Symptoms to crohns are subtle Not all, illness of course,belong to >crohns. The majority are legitimate illnesses. But crohns is weird and acts [quoted text clipped - 9 lines] >Is there a better way to put it. >Gail Advocate147 - 04 Feb 2005 01:37 GMT Not to down dentists for not knowing crohns can affect teeth. After all, nothing but the existing condition is apparent and that does not disclose the source of the problem. Medical men have slightly more awareness of the problem. They have a stubborn insistence that the cause I speak of is unscientific. So it goes on and on. sometimes undetected until surgery reveals the cause.
Gail
Joel M. Eichen - 04 Feb 2005 01:23 GMT Gail,
Have you tried MedKB?
Its a simple way to log into sci.med.dentistry!
www.medKB.com
Is this you? Or are there three steves and two gails?
"Gail L via MedKB.com" <forum@MedKB.com>
Joel
>Dr. Joel, > [quoted text clipped - 19 lines] >Is there a better way to put it. >Gail Jan - 04 Feb 2005 07:25 GMT >Subject: Re: Autoimmune disease and dental problems >From: advocate147@aol.com (Advocate147) [quoted text clipped - 4 lines] > >I am amazed. Evidently you just now seen the stupidity and lies of Joel.
> No question that an >autoimmune disease can affect the teeth. especially if crohns or Ulcerative [quoted text clipped - 19 lines] >Is there a better way to put it. >Gail You are much to kind to Joel, he's a blathering idiot.
Jan
Joel M. Eichen - 04 Feb 2005 12:50 GMT >Dr. Joel, > >I am amazed. All my words are down the drain. No question that an >autoimmune disease can affect the teeth. It is possible that the teeth and the autoimmune system interact.
Many times people have told me their teeth itch.
Joel
Tony Bad - 04 Feb 2005 13:28 GMT > Dr. Joel, > [quoted text clipped - 19 lines] > Is there a better way to put it. > Gail Gail,
I checked on Google, and here is the message you are referring to...
By the way, in checking for this on Google, I see Jan said we dentists are all useless and would never respond...that is a second apology Jan owes me that I am sure I'll never get. As we can see, she'd rather be nasty than accurate.
----------------------------------------------------------------------- Tony Bad Nov 19 2004, 9:58 am hide options
Newsgroups: sci.med.dentistry From: "Tony Bad" <SpamSpamS...@bakedbeans.spam> - Find messages by this author Date: Fri, 19 Nov 2004 17:58:19 GMT Local: Fri, Nov 19 2004 9:58 am Subject: Re: Cavitating cowards Reply to Author | Forward | Print | Individual Message | Show original | Report Abuse
"Advocate147" <advocate...@aol.com> wrote in message
news:20041119124656.06291.00000475@mb-m26.aol.com...
> Not in relation to this topic, but there are things that ONE individual can
> stumble upon. Your education far surpasses mine, and I am not saying you are
> stupid, but where in the study of dentistry, do we connect other body defaults
> to the teeth. > I will ask you, because I really don't know, does diabetes affect the teeth,
> does cancer or any other illness affect the teeth. > Never gave it any thought, and would really appreciate an answer. What other
> illnesses can affect the teeth.
> Thank You > Gail Your teeth, while alive in the sense they have a blood supply, are fully formed when you are a child, and will not show signs of disease the way other tissues may reveal. If there is a compromised saliva flow due to some systemic condition, teeth will be broken down at an accelerated rate. That said, other tissues of the oral cavity will often show signs of systemic disease. The lower jaw is one of if not the most common sites for metastatic tumors. Oral tissues are often the first to show signs of inadequate nutrition or metabolic disorders.
Here is a link to an article that can provide you with far more information than I can write up in an e-mail...
http://www.emedicine.com/derm/topic887.htm
I didn't mean to jump on you...but as I said, many people assume that all dentists are just tooth cobblers, not health care providers. Are their dentists who will ignore common and easy to detect signs of pathology? Sadly, we here cases like that quite often, but this is because people ignore or forget what they learned, not that they didn't learn it.
T
clintonz@prodigy.net - 04 Feb 2005 20:10 GMT > > Dr. Joel, > > > > I am amazed. All my words are down the drain. No question that an > > autoimmune disease can affect the teeth. especially if Obviously antything that can affect other systems can effect the teeth which are living tissue. For example, I understand (not from personal experience) that Aids can cause chronic jaw conditions such as osteomyeltis.
> Your teeth, while alive in the sense they have a blood supply, are fully > formed > when you are a child, and will not show signs of disease the way other > tissues > may reveal. If there is a compromised saliva flow due to some systemic > condition, teeth will be broken down at an accelerated rate. What would cause that? Failure to wash the bacteria off the teeth? What affect if any does saliva flow have on the hardness or chemical composition of the teeth?
In other words say person X has soft teeth, and person Y (who has the same amount of fluoride and everything else) has hard teeth, what causes the difference?
silverblue001@hotmail.com - 04 Feb 2005 21:22 GMT > > > Dr. Joel, > > > [quoted text clipped - 24 lines] > (who has the same amount of fluoride and everything else) > has hard teeth, what causes the difference? Well, I don't *really* know the answer to this, but I'm going to try anyway ...I'm sure someone will correct me. :p
Tooth decay is caused by acids in your mouth (bacteria feed on carbohydrates and produce acids as by-products). If there is a sufficient amount of saliva present, acids are diluted, buffered, and removed. Saliva also contains calcium, phosphate, and fluoride which are important in the remineralization process (from what I understand, if the processes of demineralization and remineralization are in equilibrium, the tooth does not decay). Lastly, saliva contains immunoglobins, which work against bacteria. So, if the amount of saliva in your mouth is reduced, the rate of breakdown will increase.
I don't know about the hardness of the teeth. Although I do know that dentin is softer than enamel. Taking that into account, one could say that if the enamel is broken down (which is more likely with a decreased flow of saliva), the teeth will be softer. But again, I don't know!
Advocate147 - 05 Feb 2005 12:34 GMT One post to T was sent prematurely accidentally.
If dogzoo would follow up on dental his condition, hoping to have improved it by email, everyone would be interested to know if he is better informed as to his condition thereby being better prepared to cope with it.
Gail
silverblue001@hotmail.com - 04 Feb 2005 21:28 GMT > > > Dr. Joel, > > > [quoted text clipped - 24 lines] > (who has the same amount of fluoride and everything else) > has hard teeth, what causes the difference? Well, I'm not sure I know the answer to this, but I'm going to try anyway ... someone will correct me if I'm wrong. :p
Tooth decay is caused by acids in your mouth (bacteria feed on carbohydrates and produce acids as by-products). If there is a sufficient amount of saliva present, acids are diluted, buffered, and removed. Saliva also contains calcium, phosphate, and fluoride which are important in the remineralization process (from what I understand, if the processes of demineralization and remineralization are in equilibrium, the tooth does not decay). Lastly, saliva contains immunoglobins, which work against bacteria. So, if the amount of saliva in your mouth is reduced, the rate of breakdown will increase.
Anyway, I'm procrastinating! Gotta go!
thedogzoo - 04 Feb 2005 22:10 GMT Have you been diagnosed with 'auto-immune' disease ?
If so which one ?
-- W_B
wubbabubb...@RBAGEyahoo.com Take out the G'RBAGE
I was diagnosed with autoimmune uveitis 16 years ago.
thedogzoo - 04 Feb 2005 22:17 GMT Dr. Joel,
Ok maybe I was too general in the way that I asked me question. I didn't mean it as in "Diabetes causes cavities". I meant more along the lines that it seems logical that having a systemic disease would mean that your teeth would feel the impact of the disease too. The same blood that circulates through your gums, circulates through your other organs.I also was not thinking about typical cavities as much as I was thinking about a general failure to heal from dental procedures, i.e. repeated failed root canals and apico's, recurring infections, inflammation, etc. Why do some people seem to do just fine with these procedures and others seem to have bodies that "reject" every root canal and seem to have dental infections that do not respond to antibiotics, ultimately leading to extraction of the tooth for pain relief?If an autoimmune disease is essentially a body fighting itself, wouldn't it make sense that it would fight off any other foreign matter? I'm not trying to irritate anyone...just trying to figure this out in my head. thedogzoo
Joel M. Eichen - 05 Feb 2005 03:24 GMT >Dr. Joel, > [quoted text clipped - 11 lines] >antibiotics, ultimately leading to extraction of the tooth for pain >relief? Better root canal treatment often helps!
>If an autoimmune disease is essentially a body fighting itself, >wouldn't it make sense that it would fight off any other foreign >matter? What is foreign?
A tooth is still a tooth. The obturation point, the hole that is sealed is perhaps 0.25 mm in diameter at most, if peoperly done!
Joel
> I'm not trying to irritate anyone...just trying to figure this >out in my head. thedogzoo Jan - 05 Feb 2005 02:29 GMT >Subject: Re: Autoimmune disease and dental problems >From: "Tony Bad" spamspamspam@bakedbeans.spam [quoted text clipped - 40 lines] >By the way, in checking for this on Google, I see Jan said we dentists are >all useless and would never respond. Best recheck, or arre you lying on purpose?
>.that is a second apology Jan owes me >that I am sure I'll never get. Best recheck, or arre you lying on purpose?
Could be you are in such a habit if twisting things, you did it again.
LOL.
Do recheck YOUR being accurate, then you can apoligize.
Jan
Joel M. Eichen - 05 Feb 2005 03:25 GMT >>By the way, in checking for this on Google, I see Jan said we dentists are >>all useless and would never respond. > >Best recheck, or arre you lying on purpose? We are lying on purpose ......
>>.that is a second apology Jan owes me >>that I am sure I'll never get. [quoted text clipped - 4 lines] > >LOL. Advocate147 - 05 Feb 2005 12:19 GMT Advocate147 - 05 Feb 2005 12:27 GMT T,
I, for one, plus millions and millions of others think dentists are great. Certainly Jan does too. After all, where would we all be without you. Your information on the link has been tremendous. We all look for things that will confirm our beliefs. My belief being so odd, and confirmation of it in any way is extremely welcome. Too bad there is such a strange manner in which people can be harmed with almost no clue as to the cause because it is an almost unbelievable one. Someone said to me, "find a cure for cancer, then you will be believed" Flattery or insult?, it is a tossup.
Gail
Sdores - 04 Feb 2005 17:58 GMT Joel there is. With Crohn's disease or other intestinal problems absorption is a problem especially if like me surgery is done. UM MOM Susan
>>Hello.I was wondering if any of the dentists here know of any >>correlation between an autoimmune disease and dental problems? [quoted text clipped - 9 lines] >> >>thedogzoo Joel M. Eichen - 04 Feb 2005 22:09 GMT >Joel there is. With Crohn's disease or other intestinal problems absorption >is a problem especially if like me surgery is done. UM MOM Susan Thanks.
Joel
>>>Hello.I was wondering if any of the dentists here know of any >>>correlation between an autoimmune disease and dental problems? [quoted text clipped - 9 lines] >>> >>>thedogzoo Jeff and Mary - 06 Feb 2005 14:10 GMT Hi Susan!
Joel,
Susan is right. My husband has Crohn's. After his first major flare-up, his teeth weakened. It seems that he was breaking one or two a yr. Up until the flare up his teeth were very healthy, maybe had one cavity his whole life. He also has problems with mouth sore that are related to the crohns. His dentist is a believer.
Mary
> >Joel there is. With Crohn's disease or other intestinal problems absorption > >is a problem especially if like me surgery is done. UM MOM Susan [quoted text clipped - 16 lines] > >>> > >>>thedogzoo Dr. Steve - 06 Feb 2005 18:35 GMT >Hi Susan! > [quoted text clipped - 29 lines] >> >>> >> >>>thedogzoo Teeth do not break due to autoimmune diseases. .. Stephen Mancuso, D.D.S. Troy, Michigan, USA
I am writing on a Tablet-PC,so forgive me if the PC misreads my handwriting.
Joel M. Eichen - 06 Feb 2005 18:57 GMT >>> >>>disease despite proper dental maintenance? >>> >>> >>> >>>thedogzoo > >Teeth do not break due to autoimmune diseases. REPLY
I agree, but the townspeople are gathering and their torches are getting nearer .....
>.. >Stephen Mancuso, D.D.S. >Troy, Michigan, USA > >I am writing on a Tablet-PC,so forgive me if the PC misreads my handwriting. Sdores - 06 Feb 2005 19:37 GMT They break because of malabsorption issues due to IBD and maybe other diseases. I just know crohn's and I lost most of my teeth because of malabsorption problems. UM MOM Susan
>>Hi Susan! >> [quoted text clipped - 38 lines] > I am writing on a Tablet-PC,so forgive me if the PC misreads my > handwriting. Joel M. Eichen - 06 Feb 2005 20:36 GMT >They break because of malabsorption issues due to IBD and maybe other >diseases. I just know crohn's and I lost most of my teeth because of >malabsorption problems. UM MOM Susan How is this possible?
Teeth are pretty hard! One a tooth is formed, nothing is absorbed or unabsorbed!
Joel
>>>Hi Susan! >>> [quoted text clipped - 38 lines] >> I am writing on a Tablet-PC,so forgive me if the PC misreads my >> handwriting. Dr. Steve - 06 Feb 2005 20:51 GMT >They break because of malabsorption issues due to IBD and maybe other >diseases. I just know crohn's and I lost most of my teeth because of >malabsorption problems. UM MOM Susan Nope
>>>Hi Susan! >>> [quoted text clipped - 38 lines] >> I am writing on a Tablet-PC,so forgive me if the PC misreads my >> handwriting. .. Stephen Mancuso, D.D.S. Troy, Michigan, USA
I am writing on a Tablet-PC,so forgive me if the PC misreads my handwriting.
Sdores - 06 Feb 2005 22:54 GMT Yes part of it was from surgeries and I had to wait a time to get any dental work done. My teeth died at the bone up. We take some medications too that aren't good for things like this. This is what I have been told and since I have lost all my teeth but 6 of them since 2000 when prior to getting sick my teeth where in excellent condition there is no other reason for the teeth to die all of a sudden. UM MOM Susan
>>They break because of malabsorption issues due to IBD and maybe other >>diseases. I just know crohn's and I lost most of my teeth because of [quoted text clipped - 55 lines] > I am writing on a Tablet-PC,so forgive me if the PC misreads my > handwriting. Dr. Steve - 07 Feb 2005 00:34 GMT >Yes part of it was from surgeries and I had to wait a time to get any dental >work done. My teeth died at the bone up. We take some medications too that [quoted text clipped - 62 lines] >> I am writing on a Tablet-PC,so forgive me if the PC misreads my >> handwriting. Sorry, teeth break for excessive force ( parafunction), trauma and decay. Once a tooth is formed, disease (excluding decay) does not effect it. Disease can effect saliva, antibodies, host resistance, bony support, etc. NOT the teeth themselves. .. Stephen Mancuso, D.D.S. Troy, Michigan, USA
I am writing on a Tablet-PC,so forgive me if the PC misreads my handwriting.
W_B - 07 Feb 2005 01:16 GMT >Sorry, teeth break for excessive force ( parafunction), trauma and >decay. Once a tooth is formed, disease (excluding decay) does not >effect it. Disease can effect saliva, antibodies, host resistance, >bony support, etc. NOT the teeth themselves. >.. >Stephen Mancuso, D.D.S. Right-O
-- W_B
wubbabubbazG@RBAGEyahoo.com Take out the G'RBAGE
Sdores - 07 Feb 2005 12:57 GMT Ok point taken! UM MOM Susan
>>Yes part of it was from surgeries and I had to wait a time to get any >>dental [quoted text clipped - 79 lines] > I am writing on a Tablet-PC,so forgive me if the PC misreads my > handwriting. W_B - 07 Feb 2005 01:11 GMT >Yes part of it was from surgeries and I had to wait a time to get any dental >work done. Yep untreated decay only progresses. Delaying dental treament leads to bigger problems.
-- W_B
wubbabubbazG@RBAGEyahoo.com Take out the G'RBAGE
Sdores - 07 Feb 2005 12:59 GMT Had no choice but to wait till I was healed. Cut from top to pelvic bone. Lots of healing needed. But you are right, waiting did cause problems. UM MOM Susan
>>Yes part of it was from surgeries and I had to wait a time to get any >>dental [quoted text clipped - 8 lines] > wubbabubbazG@RBAGEyahoo.com > Take out the G'RBAGE Jan - 07 Feb 2005 00:47 GMT http://www.google.com
Web Results 1 - 10 of about 115,000 for Autoimmune disease and dental problems. (0.57 seconds)
W_B - 07 Feb 2005 01:05 GMT >They break because of malabsorption issues due to IBD What's Investors Business Daily have to do with it ?
>diseases. I just know crohn's and I lost most of my teeth because of >malabsorption problems. Very, very doubtful.
>UM MOM Susan -- W_B
wubbabubbazG@RBAGEyahoo.com Take out the G'RBAGE
James Goforth - 06 Feb 2005 20:43 GMT I have an autoimmune disorder, Cogan's Syndrome. Each time the disease went into the acute stage, I would ba prescribed very high doses of corticosteroids (Decadron, Prednesone). Then my incidence of cavities went way up. I thought the steroids were to suppress my immune system and hence lowered my resistance to cavities. But the steroids gave me a voracious appetite, especially for sweets. In other words, I had an autoimmune disease and then a lot of tooth decay --but what caused the cavities: the disease? the cure? side-effect of the cure? etc. Noam sayin'?
Joel M. Eichen - 06 Feb 2005 21:51 GMT > I thought the steroids were to suppress my immune system and hence >lowered my resistance to cavities. > But the steroids gave me a voracious appetite, especially for sweets. > In other words, I had an autoimmune disease and then a lot of tooth >decay This makes sense. Bacteria love sugar!
Joel
Dr. Steve - 07 Feb 2005 00:35 GMT side-effect of the cure .. Stephen Mancuso, D.D.S. Troy, Michigan, USA
I am writing on a Tablet-PC,so forgive me if the PC misreads my handwriting.
W_B - 07 Feb 2005 01:08 GMT > I thought the steroids were to suppress my immune system and hence >lowered my resistance to cavities. [quoted text clipped - 4 lines] >the cure? etc. > Noam sayin'? It was the sugar.
-- W_B
wubbabubbazG@RBAGEyahoo.com Take out the G'RBAGE
James Goforth - 07 Feb 2005 02:11 GMT With regard to the ongoing contention that amalgam/mercury fillings are harmful: I was diagnosed with Cogan's Syndrome, an autoimmune disorder, at Mayo Clinic in Rochester, MN. It is very rare and one of those "no known cause, no real cure." I was thoroughly examined, visiting an opthalmologist, neurologist, rheumatologist, ear nose & throat doctor, among others, before it was determined what I had. And I have a LOT of mercury fillings in my mouth--about as much as you can have--and nothing was said about this rare and mysterious malady being brought about by mercury. In that Mayo is generally quite highly regarded as being on the cutting edge, I would think it to be a rather glaring omission for them to not even consider mercury as playing any part in my autoimmune disorder--especially one with no known cause otherwise--and in a person with a conspicuous amount of it in his mouth, no less. In other words, their position obviously is that mercury/amalgam wouldn't cause this. And why would I doubt those people; they're obviously very good at what they do. Given the sheer number of highly specialized doctors they had examine me, they're nothing if not thorough.
Advocate147 - 06 Feb 2005 20:59 GMT Dr. Steve,
"Teeth do not break due to autoimmune diseases."
You are right in one respect. Perhaps teeth do not break due to autoimmune diseases. But on the other hand, I do not think Crohns or Ulcerative Colitis are autoimmune diseases. They are weird illnesses and are not known to be of any certain characteristics that can be definitely called autoimmune. Crohns is a subject of much debate, in all aspects of its many features. It originally was probably an unrecognized illness, (still is in many, many, instances) then named Ileitis, and also called Regional Enteritis, all part of the alimentary canal involvement. Then as recognition of the symptoms grew, Dr. Burrill crohns name replaced the others covering the entire spector of symptoms. Teeth are affected as well as any other part of the body, the weakest parts of the body usually being the first to be affected.
Thedogzoo says he has uveitis. eye inflammation. This is a symptom of crohns also whether the doctor realizes it or not. Others with crohns have eye problems, including Jeff, Mary's husband, who as Mary said has crohns and other problems that are not of the intestinal type. Doctors did not realize those problems were crohns until later. Nothing can be dismissed with crohns as it has no regular plan or direction of symptoms. I did write to Thedogzoo by email with the hope that he was helped. crohns group is waiting for James Stein to say whether he has had surgery. I hope he has not. That is the quickest and easiest way out, but not always the necessary one. One day it will be understood for what it is. a strange phenomenom that defies science. A manmade illness. Of course not every symptom is due to crohns. The same symptoms can be of a real natural cause, but as Jan says, if in doubt, rule out crohns. It would be equally unfortunate to attribute symptoms to crohns when they are not. It is sometimes difficult to know the difference.
Gail
Joel M. Eichen - 06 Feb 2005 21:52 GMT >"Teeth do not break due to autoimmune diseases." > >You are right in one respect. Perhaps teeth do not break due to autoimmune >diseases. But on the other hand, I do not think Crohns or Ulcerative Colitis Actually too much TV causes rotted teeth. This is because people munch on candy while watching TV, so you could say TVs cause tooth decay.
Advocate147 - 06 Feb 2005 22:08 GMT Dr Joel says in a very profound statement
"Actually too much TV causes rotted teeth. This is because people munch on candy while watching TV, so you could say TV causes tooth decay."
Regular TV or cable or both? Please be specific. Thank You Gail
Joel M. Eichen - 07 Feb 2005 13:42 GMT >Dr Joel says in a very profound statement > [quoted text clipped - 5 lines] >Thank You >Gail Cable mainly.
Regular TV has commercials so you get up and exercise frequently.
Jeff and Mary - 08 Feb 2005 14:06 GMT t.v. or,
sitting at the computer?
cable wouldn't cause a problem for me. If there are no commercials, I don't go for the snacks.
Mary
> >"Teeth do not break due to autoimmune diseases." > > [quoted text clipped - 3 lines] > Actually too much TV causes rotted teeth. This is because people munch > on candy while watching TV, so you could say TVs cause tooth decay. Jan - 07 Feb 2005 00:51 GMT http://users.mrbean.net.au/~wlast/dental.html
http://tinyurl.com/5o68a
1: Neuro Endocrinol Lett. 2003 Feb-Apr;24(1-2):65-7. Related Articles, Links
Dental amalgam as one of the risk factors in autoimmune diseases.
Bartova J, Prochazkova J, Kratka Z, Benetkova K, Venclikova Z, Sterzl I.
Institute of Dental Research, lst Medical Faculty, Charles University and General Faculty Hospital Prague, Vinohradska 48, 120 60 Prague 2, Czech Republic. jirina.bart...@post.cz
BACKGROUND: Experimental and clinical data published recently show that dental amalgam can give rise to undesirable immunological responses in susceptible individuals. In genetically susceptible strains of experimental animals, mercury and silver can induce autoimmune responses. Sera of patients sensitive to mercury were found to have a higher incidence of autoantibodies relative to controls. OBJECTIVE: The aim of this study was to determine possible presence of antinuclear SSB/La autoantibodies after the in vitro stimulation of peripheral blood lymphocytes with HgCl2. METHODS: Lymphocytes were obtained from patients with autoimmune thyroiditis and increased response to mercury in vitro. Mononuclear cells were cultivated for 6 days with 100 microl HgCl2 solution or with pure medium and the levels of antinuclear autoantibodies SSB/La were assayed by a commercial SSB/La ELISA kit. RESULTS: Increased production of SSB/La autoantibodies in the media following stimulation of peripheral blood lymphocytes with HgCl2 was found in all cases. Using the Student's paired test, the results were significant on the p=0.05 significance level. CONCLUSION: Results imply that, in some patients with thyroiditis, mercury from dental amalgam can stimulate the production of antinuclear antibodies. Dental amalgam may be a risk factor in some patients with autoimmune disease.
PMID: 12743535 [PubMed - indexed for MEDLINE]
Jan - 07 Feb 2005 00:53 GMT http://www.thorne.com/townsend/oct/mercury.html
Is Mercury Toxicity an Autoimmune Disorder? by Keith W. Sehnert, M.D., Gary Jacobson, D.D.S., Kip Sullivan, J.D.
-------------------------------------------------------------------------- ------
Autoimmune Disorders The diagnostic arena now occupied by autoimmune disorders provides us with terms that could be best described as "alphabet soup." Such problems include RA (rheumatoid arthritis), HT (Hashimoto's thyroiditis), HAD (human adjuvant disease), MS (multiple sclerosis), ALS (amyotrophic lateral sclerosis or, more commonly, Lou Gehrig's disease) and MCTD (mixed connective tissue disease). Should we now add MT (mercury toxicity)? These conditions plus others, such as Crohn's disease, Raynaud's disease, systemic candidiasis, diabetes, and even Alzheimer's disease are now believed by many to be autoimmune disorders. When patients are afflicted with such disorders, they come into their physician's office with all, or some, of these symptoms: · generalized morning stiffness, · skin rashes, · dry eyes and mouth, · joint pain, · immune dysfunction, · axillary lymph node swelling, · subcutaneous nodules (skin bumps), · neurological symptoms (ringing in ears, burning and numbness sensations), · chronic fatigue, · depression and/or environmental sensitivities. The clinical assessment usually shows a connective tissue disorder, the result of the immune system attacking the tissues of the body. The immune elements of T-lymphocytes, B-cells and "PAC-man" cells, instead of attacking bacterial, viral and yeast fungal invaders, attack the cells of the thyroid (HT), joint surfaces (RA), peripheral vascular bed (Raynaud's) or the skin cells with patches across the nose and cheeks (lupus erythematosus). There are no simple answers for this perplexing group of problems, yet insights are beginning to arrive on the clinical horizon that may indicate why T-cell mediated lesions are developed and a screening questionnaire has been developed to help assess this problem (see Mercury/Toxic Metal Sensitivity Questionnaire). Patients who score more than five "yeses" should be referred to a dentist familiar with "silver" amalgam removal. Any filling in the mouth that looked silver when it was new and is gray or black now is probably 50% mercury, the rest being copper, silver, tin, and zinc. There are numerous amalgam mixes on the market. They have names like Dispersalloy®, Spheraloy®, Sybralloy®, and Tytin®. The mercury content ranges from 43 to 54%.1 Although these fillings are commonly called silver fillings because they look silver for the first few days of the eight to twelve years they survive in the average human head, mercury fillings would be a more accurate label. (And speaking of accurate labels, the origins of the word mercury are both interesting and provocative. Mercury was the God of Commerce in the Roman Empire and meant fabrication, trickery, thieving and slight of-hand.) In this article the more formal term "amalgam" is used. The name "amalgam" reflects the ability of mercury to bind or amalgamate powdered silver and other metals into a hard filling. Evidence that these fillings give systemic pathology as well as periodontal disease exists. In one study it was observed that when 50 subjects without amalgams were compared to 51 subjects with amalgams, there was a greater incidence of problems in the latter group. They experienced greater incidence of chest pains, tachycardia, anemia, fatigue and tendency to tire easily. They also had significantly higher blood pressure, lower heart rate and lower hemoglobin.2 A study in Canada has shown that pregnant sheep with new silver amalgams have elevated levels of mercury in their fetuses within two weeks of placement of the fillings. Further studies on monkeys showed the same findings. These studies were done by Vimy, Takahasi and Lorscheider at the University of Calgary, Faculty of Medicine.3 In addition to the reports from the United States, Canada and Japan, European researchers have observed many adverse reports concerning amalgams. On February 18, 1994, mercury fillings were banned in Sweden for children and youth 19 years of age because evidence showed them to be a trigger of autoimmune disorder. Although mercury fillings have been widely used in the decades since, research demonstrating that such fillings are safe has yet to be done. Research that has been done and reported in scientific literature demonstrates that: 1. Mercury escapes from fillings in the form of vapor created by chewing. It then enters the bloodstream and is delivered to all parts of the body, including the brain. (A recent autopsy of an 82-year old woman from St. Paul with confirmed Alzheimer's disease had studies done by the Mayo Heavy Metals Lab. Brain tissue examination showed 5.3 UGIG mercury (53 times normal levels). The pathologist reported "neurofibrillary tangle" in the brain sections that are common in such patients. She had multiple amalgams.) 2. People with mercury fillings have higher levels of mercury in their urine, blood and brain than people without fillings. Another significant European development about mercury amalgams was reported when Degussa AG, the largest producer of dental amalgams in Germany announced it would no longer provide such amalgams because of pending and future lawsuits. This was based on a Federal Court ruling that dentists who use such amalgams face legal liability.4 Next came a series of studies by Dr. Catherine Kousmine of France, who reported that illnesses like MS and chronic polyarthritis, both autoimmune diseases, are triggered by silver amalgams. This is outlined in her book, La Sclerosa and Plaques Est Guerissable (Multiple Sclerosis is Curable). One more European study on MS comes from Great Britain. It reports that the highest incidence of MS is found in Northern Ireland and the Scottish Island of Orkeny and Shetland. They also have the highest incidence of dental cavities and dental fillings. This provides more suspicion that mercury is a possible link to autoimmune dysfunction.
History of the debate about mercury French dentists were the first to mix mercury with various other metals and plug the mixture into cavities in teeth. The first mixtures, developed in the early 1800s, had relatively little mercury in them and had to be heated to get the metals to bind. In 1819, a man named Bell in England developed an amalgam mix with much more mercury in it that bound the metals at room temperature. Taveau in France developed a similar mixture in 1826.5 When amalgams were introduced to the US in 1833 by two French entrepreneurs, the Crawcour brothers, amalgam use was denounced by a substantial number of American dentists. So strong was the opposition to amalgams that the American Society of Dental Surgeons, formed in 1840, required its members to sign pledges promising not to use them.6 It is an intriguing historical note that the common term for mercury in Germany in those years was "quick silver." The German pronunciation for "quick" is "quack." Thus, those dentists who used mercury were called "quacks." This term has now come to mean anyone who is an "ignorant pretender to medical skill" (The Random House Dictionary of The English Language). In 1848, the Society found 11 of its New York members guilty of "malpractice for using amalgam" and suspended them. Internal debate over this issue led to the demise of the Society in 1856. Its successor organization, the American Dental Association, sought to unite dentists and, in its early days, did not take a stand on the issue of amalgam safety. The Encyclopedia Britannica reports that "amalgams were not altogether in good repute until after 1895," which suggests that the ADA was supporting the use of amalgams by then. Despite the efforts of a few researchers in this country and Europe to call attention to the dangers of mercury fillings, most notably a German chemist named Dr. Alfred Stock who published numerous articles prior to World War II,7 and Hal Huggins, a Colorado dentist who has spoken out against amalgams for the last 20 years,8 debate about the safety of mercury fillings remained muffled until recently. The amalgam safety debate was revived in this country first by a 1989 Environmental Protection Agency declaration that amalgams are a hazardous substance under the Superfund law,9 and then a December 1990 broadcast of a program by "60 Minutes" that presented a devastating critique of amalgams. The program created a stir throughout the country. "Switchboards lit up at the state dental societies, dental schools, and the American Dental Association," said Consumer Reports.10 The American Dental Association got calls from two dozen reporters. The publicity was the apparent cause of the following activity in 1991: an FDA hearing; a conference sponsored by the National Institute of Dental Research; and a call for a review of the research by the US Public Health Service. The dental establishment was furious with CBS. The ADA attacked CBS in the January 7, 1991 edition of its newspaper for "the irresponsible ways in which viewers were led to the conclusion that amalgam fillings are unsafe." To the contrary, said the ADA, "scientific evidencesuggests mercury amalgam is safe to use." The ADA newspaper published statements by Dr. Harold Loe, director of National Institute of Dental Research, criticizing CBS for having "an obvious bias" against amalgams. Dentists all over the country received information packets from the ADA, including copies of the ADA newspaper and a 1986 article from Consumer Reports. The ADA also promoted its message in a two-minutes video news release sent to 700 TV stations on December 17, 1990, on its weekly radio show on December 18, 1990, and in its journal, the Journal of the American Dental Association. The 1986 article by Consumer Reports pooh-poohed those who criticize the use of mercury in fillings. The article concluded: "Dentists who purport to treat health problems by ripping out fillings are putting their own economic welfare ahead of their patients' welfare. Except for a few people with a genuine allergy to mercury we know of no one who's been harmed by them.''11 Consumer Reports published a similar article in May of 1991 which the ADA and the MN Dental Association have also distributed widely. This article criticized research showing that silver-mercury fillings are unsafe and concluded that "amalgam fillings are still your best bet.''12 "60 Minutes" and the anti-amalgam movement have other critics besides the ADA and Consumer Reports p; they include the Arthritis Foundation, the Multiple Sclerosis Society, and the ultra-right Accuracy in Media13 p; but no one has more credibility on this issue than the ADA and Consumer Reports. For that reason, it is important for anyone trying to understand this issue to understand the arguments of these two organizations and why their arguments fail. The positions of the ADA and Consumer Reports are strikingly similar. They cite the same sources to reach the same conclusion p; that critics have not shown conclusively that mercury amalgams are unsafe.
Some Other Facts About Mercury 1. Mercury is the most toxic non-radioactive element on earth. 2. A silver colored mercury amalgam filling normally contains 52% mercury. 3. On average, amalgam filling weighs 1 gram and contains 1/2 gram of mercury. 4. The typical adult carries ten amalgam fillings containing about 5 grams of mercury. 5. 1/2 gram of mercury in a ten acre lake would warrant issuance of a fish advisory for the lake. 6. Running shoes with mercury lights in their heels were banned by the Minnesota Legislature in 1994 because they contained a 1/2 gram of mercury in them and this was considered dangerous to public health. 7. The use of mercury amalgams has been banned and are on a scheduled phaseout in Germany, Austria, Denmark and Sweden. 8. A proposition passed in California in 1994 requires a warning in dental offices using mercury amalgam stating that "the people of the state of California have determined that the use of mercury in dental amalgam causes birth defects and other health problems." The proposition also requires that permission must be obtained from a patient before placing hazardous material in the mouth. (The new law is being contested by the ADA and California Dental Association, and is tied up in Federal Court). 9. Legislation is now being proposed in Minnesota for a similar "Informed Consent" legislation for all dental patients.
Conclusion It is our conclusion that mercury toxicity is an autoimmune disorder. This was summarized recently in an article in Advance magazine.l4 Its wide range of symptoms can only be accounted for by multiple adverse effects on the immune system, nerve tissue and connective tissue in general. The Mercury/Toxic Metal Sensitivity Questionnaire has now been tested on over 200 patients and will serve as a warning/alert to clinicians when patients have scores of "yes" in five or more of the questions. Such patients should then be referred to dentists with special knowledge of mercury amalgam removal and replacement with nontoxic composites and dental materials.
Correspondence: Keith W. Sehnert, M.D. 6200 Excelsior Blvd., Suite 101 Minneapolis, Minnesota 55416 USA
References 1. Public Health Service, US Department of Health and Human Services, Dental Amalgams: A Scientific Review and Recommended Public Health Service Strategy for Research, Education and Regulation, January 1993, Washington, DC, p. 1. 2. Ziff, M. F. "Documented clinical side effect to dental amalgams." Adv. Dent. Res. 1992;1(6):131-134. 3. Vimy, J.D. Takahasi, Y., Lorscheider, F. L. "Maternal-fetal distribution of mercury released from dental amalgam fillings." Am. J. Physiol. 1990;258:939-945. 4. Brake, M. "Sweden bans amalgams." The international DAMS newsletter; Spring 1994: 1. 5. Mackert, Jr., J. Rodway, "Dental Amalgam and Mercury," Journal of the American Dental Association 122: 54-61 (1991) p. 54. 6. "Dentistry," Encyclopedia Britannica, Encyclopedia Britannica, Inc., Chicago, 1960, Vol. 7, p. 225. The US Public Health Service states: "Questions regarding its [i.e., amalgam's] safety has been raised virtually from the time of its first use." 7. Hanson, M. and Pelva, J., "The Dental Amalgam Issue: A Review," Experientia 47: 9-22 (1991). 8. Huggins, Hal H., It's All in Your Head: Diseases Caused by Silver-Mercury Fillings, 4th Ed., Life Sciences Press, 1990. 9. "Amalgam declared hazardous," Dentistry Today, February 1989, p. 1. 10. "Mercury in your mouth," Consumer Reports, May 1991, p. 316. 11. "The mercury scare" Consumer Reports, March 1986, 150-152, p. 152. 12. "The mercury in your mouth," Consumer Reports, May 1991, 316-319, p. 319. 13. "MS, arthritis groups get amalgam calls," ADA News, January 7, 1991; "CBS spurs false hopes, false fears," Accuracy in Media press release, January-B, 1991. 14. Sehnert, K. W. "Autoimmune Disorders, "Advance, January 1995, p. 47-48.
Jan - 07 Feb 2005 00:54 GMT http://www.home.earthlink.net/~berniew1/indexa.html
DENTAL AMALGAM FILLINGS PAGE
Bernie Windham- Ed.
The papers that can be linked to on this page have over 1000 medical studies or Government Agency studies that document that:
1. Dental Amalgam Fillings are the largest source of mercury in most people, and largest source of methyl mercury as well since other forms of mercury are methylated to methyl mercury in the body by bacteria, etc.
2. Most people with several fillings get significant daily exposures to mercury that exceed Government Health Guidelines for Mercury Exposure.
3. The main reasons for common high exposures of mercury and other toxic metals from amalgam are mercury's negative vapor pressure which means that it is constantly vaporizing plus the galvanic currents(battery effect) created in the mouth by mixed metals that pumps mercury into the gums, jawbone, oral mucosa, and systemically is carried throughout the body by the blood and nerves. Additionally electromagnetic fields(EMF) from appliances such as computer monitors and motors create currents in metal in the mouth that increases galvanism and exposure to metals such as mercury.
4. Mercury is extremely toxic and the most toxic substance with common significant exposures. No safe level where there are not measurable adverse effects has ever been documented. However not all people receiving the same exposure are equally effected and mercury toxicity effects depend on susceptibility factors such as immune reactivity, systemic detoxification and metal excretion ability, other synergistic exposures, etc. , as well as dose.
5. Mercury vapor or organic mercury readily crosses the blood-brain barrier and the placenta to a fetus, and accumulates to significant levels in the brain, CNS, motor neurons, hormone glands, and major organs such as the heart, kidneys, and liver in direct proportion to the number of amalgam filling surfaces. Mercury is documented to be extremely cytotoxic(kills cells), neurotoxic, and immunotoxic, as well as inducing immune reactivity in large numbers of people.
6. Mercury and other toxic, immune reactive, and carcinogenic metals like nickel form strong bonds with the hydroxyl radical(SH) in amino acids which are the body's main building blocks and cellular level fuel, disrupting the basic metabolic processes such as the conversion of cysteine to sulfates, taurine, and glutathione. The incomplete conversion of such amino acids results in toxic metabolites such as beta-casamorphine and sulfites as well as immune and autoimmune conditions.
Mercury also accumulates in the brain and CNS and damages nerve cells involved in Parkinson's and ALS through free radical formation and oxidative damage.
Some of the autoimmune condtions documented to be commonly caused by mercury(and other toxic metals) include oral lichen planus, Chronic Fatigue Syndrome(CFS), Fibromyalgia(FM), MS, Lupus, Lou Gehrig's Disease(ALS), Parkinson's, diabetes, etc.
7. Thousands of medical studies on humans and animals have confirmed the mechanisms by which mercury(and other toxic metals) cause over 40 serious or chronic health conditions including neurological, hormonal, reproductive, immune, autoimmune, cardiovascular, & birth defects and developmental effects on infants.
8. There are many thousands of clinical cases of cure or significant improvement in these conditions after proper amalgam replacement and treatment, as followed and documented by doctors. Some of the conditions that mercury has been documented to cause and which people have been documented to recover from after proper amalgam replacement or treatment include: periodontal disease, oral keratosis(pre cancer)), immune system, autoimmune problems , allergies, asthma, lupus, sinus problems, chronic headaches/ migraines, multiple chemical sensitivities, epilepsy, blood conditions, chron's disease, stomach problems, dizzyness/vertigo, arthritis, Multiple Sclerosis (MS), Lou Gehrig's Disease(ALS), Parkinson's/ muscle tremor, Alzheimer's, muscular/joint pain/fibromyalgia , infertility, depression , autism, schizophrenia, ADD, depression, insomnia, anger, anxiety & mental confusion , susceptibility to infections , antibiotic resistant infection, endometriosis , Chronic Fatigue Syndrome(CFS) , tachycardia and heart problems , memory disorders , cancer(breast,etc./ leukemia, neuropathy/paresthesia, alopecia/hair loss , tinnitus, chronic eye conditions: inflamation/iritis/ astigmatism/myopia /cataracts/macula degeneration , vision disturbances, eczema, psoriasis, skin conditions , urinary/prostrate problems, hearing loss, candida, PMS, diabetes, etc. The majority of those treated for most of these condtions showed significant improvement for most of these conditions.
9. Root canals and cavitations(incompletely healed tooth extraction sites) have been documented to often over time accumulate extremely toxic anaerobic bacteria which give off toxins that can have similar toxic effects in disrupting enzymatic processes as mercury and to be a factor in some autoimmune cases such as Parkinson's, MS, ALS, Alzheimer's, etc. Clinical trials have found infections of locally asymptomatic root-canaled teeth and cavitations to be extremely common, occurring in over 50% of root-canaled teeth and wisdom tooth extraction sites tested. New tests are available for testing for such conditions, which are commonly factors in chronic health conditions. Many are documented to have recovered from such conditions after treatment. See www.altcorp.com
10. Dental Amalgam Mercury Syndrome, Inc.(DAMS) (Florida) National web site(www.amalgam.org) is a patients support organization for those with chronic mercury conditions or who need advise about dental biocompatibilty/toxicity issues. They have lists of specially trained dentists in dealing with mercury and biocompatibility issues, and have issued several fact sheets documenting and summarizing common mercury exposure levels, adverse health and environmental effects of mercury from amalgam and other mercury sources.
11. Mercury and other toxic chemicals are accumulating in fish and wildlife to dangerous levles. The number of lakes in the U.S. with warnings regarding eating fish and wildlife has been growing rapidly and has reached over 50,000 (20% of all U.S. significant lakes), along with 7% of all U.S. river miles, all Great Lakes, and many coastal bays and estuaries. The fish and wildlife subject to these exposures are showing serious and sometimes catastropic hormonal and reproductive problems related to the accumulation of mercury and other endocrine disrupting chemicals to those at the top of the food chain such as wading birds, alligators, Florida Panthers, minks, polar bears, seals, beluga and orca whales, etc. People are also having widespread neurological, immune, hormonal, and reproductive problems related to these common exposures. Mercury from dental office and human excretion from those with amalgam fillings has been found to be a significant source of mercury into the rivers and lakes significant enough to result in warnings regarding mercury levels in fish, to the extent that the mercury levels from amalgam results in higher levels of mercury in the water of home sewers of those with amalgams and in most U.S. sewer systems higher than the EPA guideline mercury level developed to avoid accumulation in fish and wildlife and adopted by some areas for this purpose. Thus the Environmental Effects of Amalgam Dental Fillings are seen to be affecting everyone.
Home Page
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DAMS Page- Florida Chapter, Technical Documentation Page
FDA Amalgam Docket Review Page
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Jan - 07 Feb 2005 00:56 GMT http://www.dentalmaterial.gov.se/Mercury.pdf.
Jan - 07 Feb 2005 00:58 GMT http://www.toxicteeth.org/old_web_site/facts.html
Filling A Need For Mercury-Amalgam Facts By Jeff Clark & Sandy Duffy Consumers for Dental Choice NW (download printable PDF version of this article)
Dentistry has perpetrated an uncontrolled multi-generational mercury experiment on the American people. Mercury-amalgam dental fillings have never been subjected to the kind of regulatory scrutiny and approval process demanded of all modern drugs and medical devices to prove safety. Only in the last few years have controlled experiments with animals been conducted by non-dentists in an attempt to estimate what we humans have already been experiencing over the past 150+ years of mercury-amalgam.
The American Dental Association's (ADA) origin derives from the controversy of using mercury for tooth fillings. Before mercury-amalgam became the standard of dental practice only the rich could afford gold fillings -- the rest of us went to the barber for tooth extraction. Mercury-amalgam enabled dentists to place many more much lower costing tooth fillings per day. This efficiency produced an ever-widening number of people who could afford professional dental services.
The division that killed the original dental association and formed today's ADA was between those who were concerned for the public's health from the poisonous mercury release, and those who had dollar signs in their eyes [1]. Money won.
Until this day dentistry has used marketing, political influence, and control of regulatory boards at all levels to impose its self-serving economic view that mercury-amalgam is completely safe. The science that proves safety is still not forthcoming from the ADA, nor from dental schools, nor from mercury-amalgam manufacturers.
Marketing has long been dentistry's first line of defense for its use of mercury. The true nature of mercury-amalgam has been disguised with the soothing label "silver filling". Efforts to gain the public's trust and confidence have imposed high psychological barriers. For many people conditioned to trusting, it is too unbelievable, too egregious to even consider the possibility that their dentist has been poisoning them with mercury.
Science has not been the driving force behind the ADA's public information on mercury release. When asked about the safety of mercury amalgam the response one always heard previously, and can still hear today in many dental offices is: "once set, the mercury becomes completely stable and locked up, it doesn't leak out". After it was unequivocally demonstrated that mercury vapor continuously escapes from mercury-amalgam fillings the ADA repositioned itself and now claims: "the small amount of mercury released from amalgam restorations, especially during placement and removal, has not been shown to cause any adverse health effects." [2]
This last position statement made in 1997 is the one we are living under today, adopted by the dentists at the ADA, FDI World Dental Federation, and the World Health Organization in a consensus agreement.
This position is at odds with what scientists independent of the dental industry have been learning by studying amalgam mercury exposure and uptake in humans and animals.
Mercury escapes from amalgam and is taken up by the human as metallic vapor, metallic vapor and ionic mercury dissolved in saliva, and as unknown mercury species directly through the tooth pulp and root into the bloodstream.[3] Ionic mercury in saliva is converted to methylmercury.[4]
The more competent human studies on exposure have looked at the amount of mercury vapor in an individual's mouth, mercury in their saliva, mercury in their urine and feces, and compared that to individuals who have never had any mercury-amalgam fillings. There is an extreme range of dental mercury exposure and uptake from person to person. The high end of the range reaches 100 micrograms of mercury uptake per day in a single individual. That any individuals can be found with such high daily mercury exposure and uptake from their mercury-amalgam dental fillings is cause for alarm.[5] [6] [7] [8]
Animal experiments with amalgam produce further cause for alarm. There are genetically determined susceptibilities to mercury-caused systemic illness. Some animal strains are highly sensitive with quite noticeable trace mineral disturbances and immune system activation after mercury-amalgams are placed into their teeth. Other strains are highly resistant with only small pathological changes observed in response to mercury-amalgam.[9]
In genetically susceptible animals mercury concentrations in the same range as received from mercury-amalgams have been found to cause autoimmune disease, inhibiting and disturbing immune system functions.[10] [11] [12] [13] [14]
Mercury concentrations as received from mercury-amalgam are toxic to human brain cells forming neurofibrillar tangles, amyloid placques and causing tau phosphorylation in susceptible tissue cultures. [15] [16] [17] These three phenomena are the primary diagnostic characteristics a pathologist looks for in a deceased person's brain to confirm a diagnosis of Alzheimer's disease.
Mercury travels from amalgam fillings into the jaw, gut, liver, kidneys, glands and brain, crosses the placenta to the fetus, and is found in mother's milk.[18] [19] [20] [21] [22]
Dental mercury exposure in the genetically diverse and free living human population has been an uncontrolled experiment. This makes it presently difficult to prove in the absolute scientific sense that dental amalgam directly causes human health conditions beyond contact allergy and oral lichen planus. [23] [24]
This situation will change over time as genetic markers are identified for predisposition to autoimmune diseases such as MS [25], ALS [26], Lupus [27], and degenerative diseases such as Alzheimers [28] -- allowing meaningful mercury -amalgam case-control studies to be conducted within these susceptible sub-populations of humans.
New diagnostic tests characterizing human immune cells are already showing a strong correlation between immune activation against dental mercury and chronic fatigue syndromes.[29]
Young athletes that die suddenly from Idiopathic Dilated Cardiomyopathy have been shown to have 22,000 times as much mercury in their heart tissues as do patients with other cardiac conditions. [30]
Meanwhile there is an ever growing number of case reports of people receiving spontaneous remissions from a wide range of idiopathic maladies -- primarily by having mercury-amalgam dental fillings safely removed from their teeth. These experiences have led to the formation of patients' groups such as "Dental Amalgam Mercury Syndrome" (DAMS). [31]
These case reports and the current scientific evidence cry out that there is a grievous problem with mercury-amalgam dental fillings. The Hippocratic Oath commits all dentists to the conservative approach of "first do no harm". Mercury-amalgam dentistry has systematically not been living up to this pledge. The ADA cannot now reverse its position on safety without admitting fault and incurring enormous financial liability for itself and its members. Dentistry's self-serving negligence and dishonesty with mercury-amalgam "silver" fillings has put us and our children at risk.
The United States needs to pass laws to ban mercury dental fillings as soon as possible. Until that legislation is signed, the public must have the right to know about the mercury before it is placed into their teeth, to choose non-mercury fillings, and to pay the same out of pocket fee for non-mercury fillings as they would for a mercury-amalgam.
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References
1 Hardy James E, D.M.D.; "Dentistry: Stepping Out of the 1830'S"; http://www.davidhoward.com.au/Article4.html
2 ADA Statement on Dental Amalgam; http://www.ada.org/prof/prac/issues/statements/amalgam.html
3 Engqvist et al.,"Speciation of mercury excreted in feces from individuals with amalgam fillings.", Arch Environ Health, 53(3):205-13, (May-Jun 1998)
4 Leistevuo J et al., "Dental amalgam fillings and the amount of organic mercury in human saliva.", Caries Res, 35(3):163-6 (2001 May-Jun)
5 Skare et. al, "Human exposure to mercury and silver released from dental amalgam", Archives of Environmental Health: 49(5):384-94, (Sept-Oct.,1994)
6 Weiner JA, Nylander M., "An estimation of the uptake of mercury from amalgam fillings based on urinary excretion of mercury in Swedish subjects", Sci Total Environ, 168(3):255-65, (Jun 30, 1995)
7 Barregard L, et al., "People with high mercury uptake from their own dental amalgam fillings."; Occup Environ Med, 52(2):124-8, (Feb, 1995)
8 Langworth S, Stromberg R., "A case of high mercury exposure from dental amalgam", Eur J Oral Sci, 104(3):320-1, (Jun 1996)
9 Hultman et al, "Activation of the immune system and systemic immune-complex deposits in Brown Norway rats with dental amalgam restorations", J Dent Res, 77(6):1415-25, (Jun 1998)
10 Abedi-Valugerdi M, Hansson M, Moller G., "Genetic control of resistance to mercury-induced immune/autoimmune activation", Scand J Immunol, 54(1-2):190-7 (Jul-Aug 2001)
11 Bigazzi PE., "Metals and kidney autoimmunity", Environ Health Perspect, 107 Suppl 5:753-65, (Oct 1999)
12 Bagenstose LM, et al, "Murine mercury-induced autoimmunity: a model of chemically related autoimmunity in humans", Immunol Res, 20(1):67-78, (1999)
13 Johansson U, et al, "The genotype determines the B cell response in mercury-treated mice", Int Arch Allergy Immunol, 116(4):295-305, (Aug 1998)
14 Moszczynski P, "Mercury compounds and the immune system: a review", Int J Occup Med Environ Health, 10(3):247-58, (1997)
15 Olivieri G, et al, "Mercury induces cell cytotoxicity and oxidative stress and increases beta-amyloid secretion and tau phosphorylation in SHSY5Y neuroblastoma cells", J Neurochem, 74(1):231-6, (Jan 2000)
16 Pendergrass JC, Haley BE, "Inhibition of brain tubulin-guanosine 5'-triphosphate interactions by mercury: similarity to observations in Alzheimer's diseased brain", Met Ions Biol Syst, 34:461-78, (1997)
17 Pendergrass JC, et al., "Mercury vapor inhalation inhibits binding of GTP to tubulin in rat brain: similarity to a molecular lesion in Alzheimer diseased brain", Neurotoxicology, 18(2):315-24, (1997)
18 Vimy MJ, et al., "Mercury from maternal "silver" tooth fillings in sheep and human breast milk. A source of neonatal exposure", Biol Trace Elem Res, 56(2):143-52, (Feb 1997)
19 Takahashi Y, et al., "Release of mercury from dental amalgam fillings in pregnant rats and distribution of mercury in maternal and fetal tissues" Toxicology, 21;163(2-3):115-26, (Jun 2001)
20 Hahn LJ, et al., "Whole-body imaging of the distribution of mercury released from dental fillings into monkey tissues", FASEB J, 4(14):3256-60, (Nov 1990)
21 Vimy MJ, et al., "Maternal-fetal distribution of mercury (203Hg) released from dental amalgam fillings", Am J Physiol, 258(4 Pt 2):R939-45, (Apr 1990 )
22 Hahn LJ, et al., "Dental "silver" tooth fillings: a source of mercury exposure revealed by whole-body image scan and tissue analysis", FASEB J, 3(14):2641-6, (Dec 1989)
23 Kanerva L, et al., "A multicenter study of patch test reactions with dental screening series", Am J Contact Dermat, 12(2):83-7, (Jun 2001)
24 McGivern B, et al., "Delayed and immediate hypersensitivity reactions associated with the use of amalgam", Br Dent J, 22;188(2):73-6, (Jan 2000)
25 Xu C, et al., "Linkage analysis in multiple sclerosis of chromosomal regions syntenic to experimental autoimmune disease loci", Eur J Hum Genet, 9(6):458-63, (Jun 2001)
26 Robberecht W, "Genetic markers of ALS", Amyotroph Lateral Scler Other Motor Neuron Disord, 1 Suppl 2:S57-9, (Jun 2000)
27 Graham RR, et al., "Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus", Arthritis Res, 3(5):299-305, 2001
28 Poduslo SE, Yin X, "Chromosome 12 and late-onset Alzheimer's disease", Neurosci Lett, 14;310(2-3):188-90, (Sep 2001)
29 McGivern B, et al.,"Delayed and immediate hypersensitivity reactions associated with the use of amalgam", Br Dent J, 22;188(2):73-6 (Jan 2000)
30 MELISA Medica Foundation; http://www.melisa.org
31 Frustaci A, et al., "Marked elevation of myocardial trace elements in idiopathic dilated cardiomyopathy compared with secondary cardiac dysfunction", J Am Coll Cardiol, 33(6):1578-83, (May 1999)
32 Dental Amalgam Mercury Syndrome (DAMS); http://www.amalgam.org/
W_B - 07 Feb 2005 00:59 GMT >can they actually encourage dental >>> >>>disease despite proper dental maintenance? [quoted text clipped - 4 lines] >.. >Stephen Mancuso, D.D.S. Absolutely correct.
-- W_B
wubbabubbazG@RBAGEyahoo.com Take out the G'RBAGE
Jan - 07 Feb 2005 01:07 GMT http://www.ummah.net.pk/dajjal/amalg1.html
Jan - 07 Feb 2005 01:10 GMT www.nel.edu/pdf_w/24_12/ NEL241203A09_Bartova--Sterzl_wr.pdf -
Sdores - 06 Feb 2005 19:36 GMT Hi Mary! Nice to see you here. I am way backed up on emails since surgery. I'll try to get one out this week if I can sit at the computer long enough. I hope you both are well and not too cold! UM MOM Susan
> Hi Susan! > [quoted text clipped - 29 lines] >> >>> >> >>>thedogzoo Jeff and Mary - 08 Feb 2005 14:07 GMT it's actually been pretty warm, about 45 degrees.
Mary
> Hi Mary! Nice to see you here. I am way backed up on emails since surgery. > I'll try to get one out this week if I can sit at the computer long enough. [quoted text clipped - 32 lines] > >> >>> > >> >>>thedogzoo Steven Bornfeld - 04 Feb 2005 02:57 GMT > Hello.I was wondering if any of the dentists here know of any > correlation between an autoimmune disease and dental problems?Despite [quoted text clipped - 5 lines] > > thedogzoo Specifically, Sjogren's syndrome is frequently considered to have an autoimmune basis. It causes (among other symptoms) dry mouth, which often leads to severe caries.
Steve
MC60614 - 07 Feb 2005 03:08 GMT You shouldnt have any problem at all with proper hygine. Make sure you are 100% satisfied with the way they and you look before the dentures are done.. Best Of Luck, MC
W_B - 04 Feb 2005 04:36 GMT >Hello.I was wondering if any of the dentists here know of any >correlation between an autoimmune disease and dental problems?Despite [quoted text clipped - 5 lines] > >thedogzoo Have you been diagnosed with 'auto-immune' disease ?
If so which one ?
-- W_B
wubbabubbazG@RBAGEyahoo.com Take out the G'RBAGE
trychs - 27 Nov 2005 09:40 GMT http://www.freedomtoexhale.com/clinical.pd
I'm not a medical worker but the symptoms of chrons seem to b covered in the above and I'd love the opinions on this of those wit more knowledge if anyone has the time to spare? :
kureforcrohns@sbcglobal.net - 28 Nov 2005 08:59 GMT Am unable to access the link, could you please give a brief summary of its subject and content. Am not a medical worker neither, but crohns is a familiar subject, and perhaps others can tell you how it relates to teeth. Infections can be common and do not heal as quickly when the immune system is affected and I believe that implants can be unnsuccessful in the worst cases. What is it you would like to know. There is a newsgroup alt.support.crohns-colitis where the subject of crohns covers all aspects by many who are experiencing crohns or Ulcerative Colitis. The subject of teeth can be a tricky one as are all the symptoms of crohns, but would like to know what the info on the link is. Thank You Gail Michael
> http://www.freedomtoexhale.com/clinical.pdf > > I'm not a medical worker but the symptoms of chrons seem to be > covered in the above and I'd love the opinions on this of those with > more knowledge if anyone has the time to spare? :) Sdores - 28 Nov 2005 13:59 GMT What questions do you have? I have crohn's, note the spelling, do you? If you want info about crohn's there is an excellent support group called alt.support.crohn's-colitis. I looked at the link but I am not feeling well and couldn't get through the whole thing. UM MOM Susan, NOT a dentist but have had dental problems due to crohn's.
> http://www.freedomtoexhale.com/clinical.pdf > > I'm not a medical worker but the symptoms of chrons seem to be > covered in the above and I'd love the opinions on this of those with > more knowledge if anyone has the time to spare? :)
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