Medical Forum / General / Dentistry / February 2005
LOW LEVELS-Mercury Exposure
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Jan - 18 Oct 2004 02:09 GMT Research in molecular biology has elucidated mechanisms that may underlie the toxic effects of mercury.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
Joel M. Eichen - 18 Oct 2004 04:20 GMT >Mercury is one of the most toxic substances commonly encountered, and according >to Government agencies causes adverse health effects in large numbers of people [quoted text clipped - 4 lines] >the low mercury vapor pressure and galvanic current induced by mixed metals in >the mouth. RECOMMENDATIONS: Wildlife should get composites not mercury fillings .......
Jan - 18 Oct 2004 04:56 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: Joel M. Eichen joeleichen@yahoo.com [quoted text clipped - 16 lines] > >RECOMMENDATIONS: You read and stop blathering.
>he average amalgam >>filling has more than ½ gram of mercury, and has been documented to >>continuously leak mercury into the body of those with amalgam fillings due >to>the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
John Chewter - 18 Oct 2004 06:30 GMT This is an anonymous 'report' from a self appointed bunch of activists and no author, credentials or date is provided.
Brave fellows aren't they.
a.. The Florida League of Conservation Voters (FLCV) has for 27 years served as the non-partisan advocacy and educational arm of the environmental/conservation movement in Florida.
a.. FLCV is an informal coalition of activists and leaders from environmental and conservation organizations throughout Florida.
a.. The FLCV Advisory Board currently consists of more than 100 environmental activists from organizations and communities around the state.
> >Subject: Re: LOW LEVELS-Mercury Exposure >>From: Joel M. Eichen joeleichen@yahoo.com [quoted text clipped - 204 lines] > methylmercury result in dopamine and norepinephrine brain neurotransmitter > changes. Jan - 18 Oct 2004 06:52 GMT >From: "John Chewter" Stomping his feet and covering his eyes.
Whine, whine, whine =====
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to>the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
John Chewter - 18 Oct 2004 13:25 GMT Anybody could have written that. Doesn't say if it was a Dentist or Janitor. I am assuming Janitor.
You may be danger of being regarded, in some less understanding circles, as an irresponsible ranting poster...........
ROTFLMAO!
Dora - 18 Oct 2004 17:08 GMT >Anybody could have written that. Doesn't say if it was a Dentist or Janitor. >I am assuming Janitor. See the movie "Good Will Hunting". lol - genius janitor -
>You may be danger of being regarded, in some less understanding circles, as >an irresponsible ranting poster........... > >ROTFLMAO! Jan - 19 Oct 2004 02:22 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: eldorsvgb@yahoo.com (Dora) >Date: 10/18/2004 8:08 AM Pacific Standard Time >Message-id: <4173eb28.3863880@news.infostations.com> Research in molecular biology has elucidated mechanisms that may underlie the toxic effects of mercury.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
Dora - 18 Oct 2004 17:08 GMT >Anybody could have written that. Doesn't say if it was a Dentist or Janitor. >I am assuming Janitor. The dentist has the disadvantage of dental college indoctrination. The janitor, the toxicologist, the lawmaker, the old lady, any five year old can easily be more objective on the topic of mercury fillings than the dentist.
>You may be danger of being regarded, in some less understanding circles, as >an irresponsible ranting poster...........
>ROTFLMAO! Jan - 19 Oct 2004 02:23 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: eldorsvgb@yahoo.com (Dora) >Date: 10/18/2004 8:08 AM Pacific Standard Time >Message-id: <4173eb2e.3869626@news.infostations.com> Research in molecular biology has elucidated mechanisms that may underlie the toxic effects of mercury.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
John Chewter - 25 Oct 2004 00:03 GMT The janitor, the toxicologist, the lawmaker, the old lady, any five year old can easily be more objective on the topic of mercury fillings than the dentist.
This is errant nonsense. If your baby is dieing you go to a top paediatrician for advice - even if the 'five year old' could be more objective. Jeesh!
Jan - 25 Oct 2004 03:26 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: "John Chewter" john@LESS_SPAMchewter.f9.co.uk [quoted text clipped - 8 lines] >paediatrician for advice - even if the 'five year old' could be more >objective. Jeesh! Research in molecular biology has elucidated mechanisms that may underlie the toxic effects of mercury.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
Joel M. Eichen - 25 Oct 2004 11:59 GMT >Research in molecular biology has elucidated mechanisms that may underlie the >toxic effects of mercury. MOLECULAR .... four syllables ...... a record for the JanSter.
Dora - 18 Oct 2004 17:08 GMT >You may be danger of being regarded, in some less understanding circles, as >an irresponsible ranting poster........... Jan is always a lady.
>ROTFLMAO! carabelli - 18 Oct 2004 17:10 GMT > >You may be danger of being regarded, in some less understanding circles, as > >an irresponsible ranting poster........... > > Jan is always a lady. Well count me out for double checking that one.
carabelli
Jan - 19 Oct 2004 02:23 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: eldorsvgb@yahoo.com (Dora) >Date: 10/18/2004 8:08 AM Pacific Standard Time >Message-id: <4173eb38.3880463@news.infostations.com> Research in molecular biology has elucidated mechanisms that may underlie the toxic effects of mercury.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
Dr Steve - 19 Oct 2004 13:44 GMT Jan, I think your software "burped" as your post was repeated 3-4 times.
 Signature ~+--~+--~+--~+--~+-- Stephen Mancuso, D.D.S. Troy, Michigan, USA ....................................................
This posting is intended for informational or conversational purposes only. Always seek the opinion of a licensed dental professional before acting on the advice or opinion expressed here. Only a dentist who has examined you in person can diagnose your problems and make decisions which will affect your health. ......................
> >Subject: Re: LOW LEVELS-Mercury Exposure >>From: eldorsvgb@yahoo.com (Dora) [quoted text clipped - 180 lines] > methylmercury result in dopamine and norepinephrine brain neurotransmitter > changes. Steven Fawks - 19 Oct 2004 15:26 GMT You are too kind.
Fawks
> J**, I think your software "burped" as your post was repeated 3-4 times. W_B - 19 Oct 2004 16:25 GMT >Jan, I think your software "burped" as your post was repeated 3-4 times. You have assumed the wrong end of the alimentary tract. --
W_B
Take out the G'RBAGE wubbabubbazG@RBAGEyahoo.com
Joel M. Eichen - 19 Oct 2004 20:50 GMT >>Jan, I think your software "burped" as your post was repeated 3-4 times. > >You have assumed the wrong end of the alimentary tract. Just my thouights too!
That post SMELLED ,,,, actually the proper word is stank.
Jan - 19 Oct 2004 23:28 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: "Dr Steve" nospam@home.net >Date: 10/19/2004 4:44 AM Pacific Standard Time >Message-id: <o_7dd.10438$q71.7071@newssvr16.news.prodigy.com> > >Jan, I think your software "burped" as your post was repeated 3-4 times No, it didn't burp, I will continue to do that when the new stalker John comes on with his insulting or the usual blathering from both W_B and Joel.
Joel M. Eichen - 20 Oct 2004 00:13 GMT >>Subject: Re: LOW LEVELS-Mercury Exposure >>From: "Dr Steve" nospam@home.net [quoted text clipped - 5 lines] >No, it didn't burp, I will continue to do that when the new stalker John comes >on with his insulting or the usual blathering from both W_B and Joel. I will continue to continue .......
Its BALTHERING .......
Jan - 20 Oct 2004 01:13 GMT >LEVELS-Mercury Exposure >From: Joel M. Eichen Research in molecular biology has elucidated mechanisms that may underlie the toxic effects of mercury.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
John Chewter - 20 Oct 2004 00:20 GMT You need professional help.
> >Subject: Re: LOW LEVELS-Mercury Exposure >>From: "Dr Steve" nospam@home.net [quoted text clipped - 6 lines] > comes > on with his insulting or the usual blathering from both W_B and Joel. Jan - 20 Oct 2004 01:14 GMT >LEVELS-Mercury Exposure >From: "John Chewter"
>You This is about me, it's about the lies told here. LOW LEVELS of mercury cause damage.
Research in molecular biology has elucidated mechanisms that may underlie the toxic effects of mercury.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
John Chewter - 20 Oct 2004 06:38 GMT It is about time this newsgroup was moderated.
You continually flout all net rules
> >LEVELS-Mercury Exposure >>From: "John Chewter" [quoted text clipped - 184 lines] > methylmercury result in dopamine and norepinephrine brain neurotransmitter > changes. Jan - 20 Oct 2004 07:12 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: "John Chewter" john@LESS_SPAMchewter.f9.co.uk >Date: 10/19/2004 9:38 PM Pacific Standard Time >Message-id: <cl4tk0$lcj$1@sparta.btinternet.com> > >It is about time this newsgroup was moderated. LOL!!!!!
>>You >> [quoted text clipped - 181 lines] >> methylmercury result in dopamine and norepinephrine brain neurotransmitter >> changes. John Chewter - 20 Oct 2004 10:12 GMT >It is about time this newsgroup was moderated. It can be done. If ever I saw a site that needed moderating - it is this one.
That way you get to say what you want. Once.
:) Jan - 20 Oct 2004 19:54 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: "John Chewter" john@LESS_SPAMchewter.f9.co.uk [quoted text clipped - 9 lines] > >:) Guess you would need to shut up.
I post studies and dangers of amalgams.
John Chewter - 20 Oct 2004 20:55 GMT You are a ranting, harpy.
> >Subject: Re: LOW LEVELS-Mercury Exposure >>From: "John Chewter" john@LESS_SPAMchewter.f9.co.uk [quoted text clipped - 13 lines] > > I post studies and dangers of amalgams. Jan - 20 Oct 2004 22:44 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: "John Chewter" john@LESS_SPAMchewter.f9.co.uk >Date: 10/20/2004 11:55 AM Pacific Standard Time >Message-id: <cl6fr7$8tv$1@titan.btinternet.com> > >You are a ranting, harpy. This isn't about me.
Joel M. Eichen - 20 Oct 2004 08:06 GMT >>LEVELS-Mercury Exposure >>From: "John Chewter" [quoted text clipped - 3 lines] >This is about me, it's about the lies told here. LOW LEVELS of mercury cause >damage. Break Dancing story coming on ......
John Chewter - 20 Oct 2004 00:22 GMT Repeating stuff 10 times does not make it more true. But it can make you look stupid and nagging.
> >Subject: Re: LOW LEVELS-Mercury Exposure >>From: "Dr Steve" nospam@home.net [quoted text clipped - 6 lines] > comes > on with his insulting or the usual blathering from both W_B and Joel. Jan - 20 Oct 2004 01:15 GMT >From: "John Chewter" <snip whining>
Research in molecular biology has elucidated mechanisms that may underlie the toxic effects of mercury.
Studies of the effects of mercury on the immune system in rodents have enhanced knowledge of the mechanisms whereby mercury affects the immune system. Clinical studies of occupationally exposed employees have objectively confirmed subclinical influence of mercury on the immune system at low levels of mercury exposure.
The thyroid has been identified as the target organ for the toxic effect of mercury in occupational exposure to mercury vapour in low doses.
Clinical studies of the effects of mercury on occupationally exposed workers, using modern diagnostic methods, have elucidated the connection between dose and effect. They have also identified and quantified neuropsychological symptoms at low exposure levels.
Relation between symptoms and mercury concentrations in saliva after chewing. The Tübingen amalgam study could establish in the especially examined group of 21-40 year old persons a statistically significant relation between mercury levels in saliva and symptoms. Only symptoms which are characteristic of subacute or chronic mercury exposure in the low-level range were studied.
Low-level chronic exposures to mercury may affect the peripheral nervous system resulting in polyneuropathies (reduced sensory and motor nerve function) and neuropsychological effects (visual alterations, sensory loss, stress) (ATSDR 1989); these effects correlate to tissue levels of 20 to 40 µg/g. Neuropsychological effects were also reported by Smith et al. (1970) for occupational exposure to mercury levels of > 0.1 mg/m3. Mercury concentrations below this value did not appear to cause observable effects. Kishi et al. (1993) reported that neurobehavioral and motor function effects persisted in ex-mercury miners more than 10 years after cessation of exposure.
Once inhaled, elemental mercury is mostly converted to an inorganic divalent or mercuric form by catalase in the red blood cells. This inorganic form has similar properties to organic mercury. Small amounts of non-oxidized elemental mercury continue to persist and account for CNS toxicity.
Elemental mercury, as a vapor, which escapes from fillings, penetrates the blood-brain-barrier and enters the CNS, where it's ionized and trapped, attributing to its significant toxic effects
http://www.floridalcv.org/FLCVEdFund/environmental_effect_of_dental_a.htm
Environmental Effect of Dental Amalgam
Mercury is one of the most toxic substances commonly encountered, and according to Government agencies causes adverse health effects in large numbers of people in the U.S.[1] The extreme toxicity of mercury can be seen from documented effects on wildlife by very low levels of mercury exposure. The average amalgam filling has more than ½ gram of mercury, and has been documented to continuously leak mercury into the body of those with amalgam fillings due to the low mercury vapor pressure and galvanic current induced by mixed metals in the mouth.
1. Hg plasma concentration correlated with no.of amalgam fillings. http://tinyurl.com/cdb0 2003
2. Correlation between number of fillings and salivary Hg. http://tinyurl.com/cgs 2000
3. The amount of organic and inorganic mercury in paraffin-stimulated saliva was significantly higher in subjects with dental amalgam fillings http://tinyurl.com/cgs1 2001 4. Mercury vapour release increases with chewing, with absorption and uptake by the brain and kidneys. http://tinyurl.com/cczd 2002
5. Amalgam causes nerve cell toxicity in culture. http://tinyurl.com/ccyo 2003
6. Plasma concentrations of mercury before and after treatment supported the metal exposure to be causative for the ill health. http://tinyurl.com/ccyr 2002
7 None of the materials tested consistently prevented microleakage. http://tinyurl.com/cfcg 2002
8. In neither of the nonamalgam groups was this [wastewater] limit exceeded, but 20.5% in the amalgam group exceeded the limit http://tinyurl.com/ccyu 2002
9. I-Hg levels in placenta increased with an increasing number of maternal dental amalgam fillings (p < 0.001)... a substantial fraction of maternal blood I-Hg, probably as Hg(0), reached the fetus. http://tinyurl.com/cgrz 2002
10 Evidence of a pro-oxidant role of the amalgam Hg chronically released in saliva. http://tinyurl.com/cgrv 2002 11. Mercury released into air from dry abraded amalgam was shown to be above the recommended industrial limit http://tinyurl.com/cf7j 2002
http://www.chem-tox.com/pregnancy/mercury.htm
Low Level Mercury Causes Behavior Problems During Pregnancy
Subtle behavior problems were observed in mice offspring exposed to a single low level mercury dose.
In summarizing the results of their study, the researchers stated,
"This hypothesis generating study showed highly significant correlations between mood scores and most measures of low level Hg (mercury) exposure. The specific mood measures most associated with Hg exposure were tension, fatigue, and confusion. The strength of these associations suggests that mood should be included for investigation in future hypothesis-testing studies..... Among the cognitive and motor function tests, only the digit span and simple reaction time (nondominant hand) scores were associated with any measure of exposure...... Overall, and despite the small size of the study population, this investigation found some evidence of adverse preclinical effects at mercury doses averaging 36 ugs/l in urine. The mood and symptom results of this study agree with prior evaluations of both high and low urinary mercury doses. These preliminary survey findings support a critical evaluation of the adequacy of the 50 ug/g creatinine biologic threshold for mercury proposed by the World Health Organization This is the first U.S. dental study to detect potential behavioral deficits at such a low level of exposure. A larger and more comprehensive study is required to accurately determine a biologic threshold of adverse central and peripheral nervous system effects for elemental mercury."
Drs. Diana Echeverria, Nicholas J. Heyer, Michael D. Martin, Conrad A Naleway Depart. of Environ. Health, Univ. of Washington, School of Dentistry, Univ. of Washington Neurotoxicology and Teratology, Vol. 17(2):161-168, 1995
Dopamine Uptake in Brain Cells Changed By Methylmercury
Attention Deficit Disorder children were reported in other headings in this book as having altered dopamine levels. Several compounds, including alcohol, have been shown to alter dopamine levels in test animals. Now, researchers at Duke University Medical School have shown that even very low levels of methylmercury result in dopamine and norepinephrine brain neurotransmitter changes.
John Chewter - 20 Oct 2004 06:39 GMT Continually reposting the same thing makes you look even more silly.
> >From: "John Chewter" > [quoted text clipped - 179 lines] > methylmercury result in dopamine and norepinephrine brain neurotransmitter > changes. Jan - 20 Oct 2004 07:14 GMT >From: "John Chewter"
>you
> This is about me, it's about the lies told here. LOW LEVELS of mercury > cause [quoted text clipped - 179 lines] > methylmercury result in dopamine and norepinephrine brain neurotransmitter > changes. John Chewter - 20 Oct 2004 10:11 GMT >This is about me Its supposed to be about dentistry - not about you.
Jan - 20 Oct 2004 19:52 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: "John Chewter" john@LESS_SPAMchewter.f9.co.uk [quoted text clipped - 4 lines] > >Its supposed to be about dentistry - not about you. Indeed, glad you finally caught on.
Low levels of mercury exposure comes from amalgams and causes health problems. Dentists need to wake up to that fact, along with ruining the enviornment.
Way past time to ban amalgams, as we now have a mercury reduction act.
John Chewter - 20 Oct 2004 20:56 GMT At last.
:) I placed a post today supporting that.
> >Subject: Re: LOW LEVELS-Mercury Exposure >>From: "John Chewter" john@LESS_SPAMchewter.f9.co.uk [quoted text clipped - 12 lines] > > Way past time to ban amalgams, as we now have a mercury reduction act. Dr Steve - 20 Oct 2004 16:31 GMT But, it chisels away at your believability when you constantly re-post the exact same message (especially in the same thread).
 Signature ~+--~+--~+--~+--~+-- Stephen Mancuso, D.D.S. Troy, Michigan, USA ....................................................
This posting is intended for informational or conversational purposes only. Always seek the opinion of a licensed dental professional before acting on the advice or opinion expressed here. Only a dentist who has examined you in person can diagnose your problems and make decisions which will affect your health. ......................
> >Subject: Re: LOW LEVELS-Mercury Exposure >>From: "Dr Steve" nospam@home.net [quoted text clipped - 6 lines] > comes > on with his insulting or the usual blathering from both W_B and Joel. Jan - 20 Oct 2004 20:05 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: "Dr Steve" nospam@home.net [quoted text clipped - 3 lines] >But, it chisels away at your believability when you constantly re-post the >exact same message (especially in the same thread). A truth’s initial commotion is directly proportional to how deeply the lie was believed…When a well-packaged web of lies has been sold gradually to the masses over generations, the truth will seem utterly preposterous and its speaker, a raving lunatic. -Dresden James
Adenosine - 20 Oct 2004 20:15 GMT >>Subject: Re: LOW LEVELS-Mercury Exposure >>From: "Dr Steve" nospam@home.net [quoted text clipped - 8 lines] >masses over generations, the truth will seem utterly preposterous and its >speaker, a raving lunatic. -Dresden James Maybe you should out-sell the liars?
You need to get some books on marketing from the library!
Adenosine
Jan - 20 Oct 2004 22:45 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: Adenosine adeno@nospam4u.org [quoted text clipped - 11 lines] >>A truth’s initial commotion is directly proportional to how deeply the lie >>was believed…When a well-packaged web of lies has been sold gradually to the
>>masses over generations, the truth will seem utterly preposterous and its >>speaker, a raving lunatic. -Dresden James [quoted text clipped - 4 lines] > >Adenosine Haven't the slighest interest in marketing.
John Chewter - 20 Oct 2004 22:47 GMT >You need to get some books on marketing from the library! I have a degree in Marketing. I expect you have a cat. Joel, of course, has a hot water bottle.
:) Adenosine - 20 Oct 2004 22:49 GMT >>You need to get some books on marketing from the library! > >I have a degree in Marketing. I expect you have a cat. Joel, of course, has >a hot water bottle. > >:) This post confuses me greatly.
Adenosine
StovePipe - 21 Oct 2004 05:07 GMT > >>You need to get some books on marketing from the library! > > [quoted text clipped - 6 lines] > > Adenosine Beware of low-flying Mercury... SP
 Signature Not a real Addy, yet
John Chewter - 25 Oct 2004 20:56 GMT SP is right on the money. Note that nobody contested it tho'
>> >>You need to get some books on marketing from the library! >> > [quoted text clipped - 3 lines] >> > >> >:) Adenosine - 25 Oct 2004 21:07 GMT >SP is right on the money. >Note that nobody contested it tho' Still confused.
Maybe it's a genetic thing...
Adenosine
John Chewter - 25 Oct 2004 23:57 GMT Or a Brit humour thing.
>>SP is right on the money. >>Note that nobody contested it tho' [quoted text clipped - 4 lines] > > Adenosine Adenosine - 26 Oct 2004 00:24 GMT >Or a Brit humour thing. I thought we were talking about mercury, not dead parrots.
Adenosine
Dr Steve - 26 Oct 2004 13:54 GMT That was a great skit!
 Signature ~+--~+--~+--~+--~+-- Stephen Mancuso, D.D.S. Troy, Michigan, USA ....................................................
This posting is intended for informational or conversational purposes only. Always seek the opinion of a licensed dental professional before acting on the advice or opinion expressed here. Only a dentist who has examined you in person can diagnose your problems and make decisions which will affect your health. ......................
> >>Or a Brit humour thing. > > I thought we were talking about mercury, not dead parrots. > > Adenosine John Chewter - 20 Oct 2004 22:45 GMT >A truth's initial commotion is directly proportional to how deeply the lie was believed.
Quoting rubbish does not make it true. That is an opinion expressed as fact.
He made mistakes. This is why he had an eraser on his pencil.
Jan - 21 Oct 2004 01:56 GMT >Subject: Re: LOW LEVELS-Mercury Exposure >From: "John Chewter" john@LESS_SPAMchewter.f9.co.uk [quoted text clipped - 7 lines] > >He made mistakes. This is why he had an eraser on his pencil. A truth’s initial comm
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