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Medical Forum / General / Cardiology / December 2007

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High-fat, high-carb meals more harmful to obese, oxidative stress and     inflammation

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aria - 29 Dec 2007 00:14 GMT
High-fat, high-carb meals more harmful to obese

Dec 28, 2007

Eating a high-fat, high-carb fast food meal produces damaging cellular
changes that are greater and longer-lasting in obese people than in
normal-weight people, a new study shows.

Dr. Paresh Dandona and colleagues from Kaleida Health in Buffalo, New
York looked at inflammation and oxidative stress, which occurs when
levels of normal byproducts of metabolism known as free radicals
exceed the body's ability to neutralize them.

In previous research they found that obese individuals have higher
levels of v than normal-weight individuals. They also demonstrated
that eating a high-fat, high-carb meal increased oxidative stress and
inflammation in normal-weight people.

To test whether these increases might be greater in obese people,
Dandona and his team had 10 normal-weight and 8 obese people eat a
1,800-calorie meal consisting of a large hamburger, a large serving of
fries, a large cola, and a slice of apple pie.

Both groups showed increases in oxidative stress two hours after
eating the meal. By three hours, oxidative stress had returned to
baseline levels in the normal-weight individuals, but it continued to
climb in the obese individuals. The same pattern was seen for
inflammation.

"If obese people who already have oxidative and inflammatory stress
take the same meal, they get far greater and more prolonged levels of
oxidative and inflammatory stress," Dandona told Reuters Health.
"Since oxidative and inflammatory stress predispose you to
atherosclerosis (hardening of the arteries), heart attack and stroke,
this risk is far greater in obese people."

In another study, Dandona and his colleagues demonstrated that a high-
fruit, high-fiber meal with the same calorie content as the fast food
meal tested in the current study produced no increase in oxidative or
inflammatory stress.

The findings provide yet more evidence that people should avoid high-
fat, high carb fast food meals and consume as much fruit and
vegetables as possible, Dandona said.

SOURCE: The Journal of Clinical Endocrinology & Metabolism, November

Copyright © 2007 Reuters Limited.
Andrew B. Chung, MD/PhD - 29 Dec 2007 01:16 GMT
> High-fat, high-carb meals more harmful to obese
>
[quoted text clipped - 3 lines]
> changes that are greater and longer-lasting in obese people than in
> normal-weight people, a new study shows.

Yes, overeating is harmful for everyone so that it remains wiser for
everyone to eat less, down to the optimal amount to become healthier
(hungrier) than ever:

http://HeartMDPhD.com/EatLess

> Dr. Paresh Dandona and colleagues from Kaleida Health in Buffalo, New
> York looked at inflammation and oxidative stress, which occurs when
[quoted text clipped - 10 lines]
> 1,800-calorie meal consisting of a large hamburger, a large serving of
> fries, a large cola, and a slice of apple pie.

A large hamburger would weigh 14 to 16 ounces.

A large serving of fries would weigh 8 to 12 ounces.

A large cola would be 20 ounces.

A slice of apple pie would weigh 4 to 6 ounces.

This would be a total of 46 to 54 ounces of food for one meal, which
is clearly excessive.

The optimal amount is 32 ounces for the entire day.

> Both groups showed increases in oxidative stress two hours after
> eating the meal.

Not surprising.

> By three hours, oxidative stress had returned to
> baseline levels in the normal-weight individuals, but it continued to
[quoted text clipped - 12 lines]
> meal tested in the current study produced no increase in oxidative or
> inflammatory stress.

No **decrease** either, however.

> The findings provide yet more evidence that people should avoid high-
> fat, high carb fast food meals and consume as much fruit and
> vegetables as possible, Dandona said.

Wiser to eat less, down to the optimal amount, in order to
**decrease** oxidative stress thereby become healthier (hungrier) in
order to lose the VAT and cure the insulin resistance (IR/MetS) and
possibly type-2 diabetes if already present:

http://HeartMDPhD.com/EatLess

May you and other dear neighbors, friends, and family have a blessedly
wonderful New Years ...

... by being hungrier:

http://TruthRUS.org/BeRight

Hunger is wonderful :-)

It's how we know what GOD wants, which is what is good.

Yes, hunger is our knowledge of good versus evil that Adam and Eve
paid for with their and our immortal lives.

However, there are crazy folks, who have rejected this knowledge and
are perishing as predicted by the prophecy of 2 Thessalonians
2:9-11...

http://HeartMDPhD.com/Convicts/CrazyOne

Be hungry... be healthy... be hungrier... be blessed:

http://HeartMDPhD.com/HolySpirit/BeBlessed

"Blessed are you who hunger NOW...

... for you will be satisfied." -- LORD Jesus Christ (Luke 6:21)

Amen.

Prayerfully in the infinite power and might of the Holy Spirit,

Andrew <><
--
Andrew B. Chung, MD/PhD
Lawful steward of http://EmoryCardiology.com
Bondservant to the KING of kings and LORD of lords.
J666 - 29 Dec 2007 01:33 GMT
On Dec 28, 7:16 pm, "Andrew B. Chung
> It's how we know what GOD wants, which is what is good.

If that is the GOD who is not critical of your comments in:

http://groups.google.com/group/sci.med.cardiology/browse_thread/thread/62ffd3c0b
9d7247c/05695702c16bd4f7#05695702c16bd4f7


then, the GOD in your statement, does not know what is meant as good.

Shame shame shame on you Chung.
Andrew B. Chung, MD/PhD - 29 Dec 2007 01:35 GMT
http://HeartMDPhD.com/Convicts/Rebukesatan

<><

May everyone else have a blessedly wonderful New Years ...

... by being hungrier:

http://TruthRUS.org/KnowingGOD

Hunger is wonderful :-)

It's how we know what GOD wants, which is what is good.

Yes, hunger is our knowledge of good versus evil that Adam and Eve
paid for with their and our immortal lives.

However, there are crazy folks, who have rejected this knowledge and
are perishing as predicted by the prophecy of 2 Thessalonians
2:9-11...

http://HeartMDPhD.com/Convicts/CrazyOne

Be hungry... be healthy... be hungrier... be blessed:

http://HeartMDPhD.com/HolySpirit/BeBlessed

"Blessed are you who hunger NOW...

... for you will be satisfied." -- LORD Jesus Christ (Luke 6:21)

Amen.

:-)))
J666 - 29 Dec 2007 01:43 GMT
On Dec 28, 7:35 pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> http://HeartMDPhD.com/Convicts/Rebukesatan
>
[quoted text clipped - 30 lines]
>
> :-)))

Shame shame shame. Chung you have no human decency or are crazy.  Your
true persona has shown through for all to see.  Multiple posts will
not change a thing.
Andrew B. Chung, MD/PhD - 29 Dec 2007 01:55 GMT
http://HeartMDPhD.com/Convicts/Rebukesatan

<><

May everyone else have a blessedly wonderful New Years ...

... by being hungrier:

http://TruthRUS.org/KnowingGOD

Hunger is wonderful :-)

It's how we know what GOD wants, which is what is good.

Yes, hunger is our knowledge of good versus evil that Adam and Eve
paid for with their and our immortal lives.

However, there are crazy folks, who have rejected this knowledge and
are perishing as predicted by the prophecy of 2 Thessalonians
2:9-11...

http://HeartMDPhD.com/Convicts/CrazyOne

Be hungry... be healthy... be hungrier... be blessed:

http://HeartMDPhD.com/HolySpirit/BeBlessed

"Blessed are you who hunger NOW...

... for you will be satisfied." -- LORD Jesus Christ (Luke 6:21)

Amen.

:-)))
J666 - 29 Dec 2007 02:20 GMT
On Dec 28, 7:55 pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> http://HeartMDPhD.com/Convicts/Rebukesatan
>
[quoted text clipped - 30 lines]
>
> :-)))

Pathetic repetitive response.  You either do not understand what you
did or do not have the decency to apologize.
Andrew B. Chung, MD/PhD - 29 Dec 2007 03:40 GMT
http://HeartMDPhD.com/Convicts/Rebukesatan

<><

May everyone else have a blessedly wonderful New Years ...

... by being hungrier:

http://TruthRUS.org/KnowingGOD

Hunger is wonderful :-)

It's how we know what GOD wants, which is what is good.

Yes, hunger is our knowledge of good versus evil that Adam and Eve
paid for with their and our immortal lives.

However, there are crazy folks, who have rejected this knowledge and
are perishing as predicted by the prophecy of 2 Thessalonians
2:9-11...

http://HeartMDPhD.com/Convicts/CrazyOne

Be hungry... be healthy... be hungrier... be blessed:

http://HeartMDPhD.com/HolySpirit/BeBlessed

"Blessed are you who hunger NOW...

... for you will be satisfied." -- LORD Jesus Christ (Luke 6:21)

Amen.

:-)))
BusinessAccountEmail@gmail.com - 29 Dec 2007 05:00 GMT
On Dec 28, 9:40 pm, "Andrew B. Chung, MD/PhD"
<heartdo...@emorycardiology.com> wrote:
> http://HeartMDPhD.com/Convicts/Rebukesatan
>
[quoted text clipped - 30 lines]
>
> :-)))

This does seem to be another example that Chung's Brain is a bot.
Andrew B. Chung, MD/PhD - 29 Dec 2007 08:55 GMT
satan via a sockpuppet (corporeal demon) hissed:
> Andrew, in the Holy Spirit, boldly wrote:
>
[quoted text clipped - 34 lines]
>
> This does seem to be another example that Chung's Brain is a bot.

<><
aria - 29 Dec 2007 09:43 GMT
> > To test whether these increases might be greater in obese people,
> > Dandona and his team had 10 normal-weight and 8 obese people eat a
[quoted text clipped - 11 lines]
> This would be a total of 46 to 54 ounces of food for one meal, which
> is clearly excessive.

According to McDonald's USA, http://app.mcdonalds.com/bagamcmeal
a Big Mac is total serving weight 7.5 oz (540 cal),
a large fries is 6 oz (570 cal),
an apple pie 2.7 oz (270 cal)
a large Coke is 32 fl-oz (310 cal)

This "meal" would equal 1,700 cal at 16 oz avdp, plus soda carb value
about 3 oz sugar. 72 grams fat, inc 19 grams sat fat. 237 grams carbs.
33 grams protein. 14 grams fiber, and 1580 mg sodium.

a
Andrew B. Chung, MD/PhD - 29 Dec 2007 10:06 GMT
> Andrew, in the Holy Spirit, boldly wrote:
>
[quoted text clipped - 16 lines]
> According to McDonald's USA, http://app.mcdonalds.com/bagamcmeal
> a Big Mac is total serving weight 7.5 oz (540 cal),

Depends on the person fixing the Big Mac for you.  If s/he likes you,
you will get more food :-)

> a large fries is 6 oz (570 cal),

Again, it depends on the person serving you.

> an apple pie 2.7 oz (270 cal)

This is not a "slice of apple pie."

> a large Coke is 32 fl-oz (310 cal)

This will depend on the amount of ice.

Nonetheless, this adds up to 48.2 ounces of food, which is within the
range of 46 - 54 ounces given earlier.

Again, this is excessive because 32 ounces of food is optimal for the
**whole** day:

http://HeartMDPhD.com/EatLess

> This "meal" would equal 1,700 cal at 16 oz avdp, plus soda carb value
> about 3 oz sugar. 72 grams fat, inc 19 grams sat fat. 237 grams carbs.
> 33 grams protein. 14 grams fiber, and 1580 mg sodium.

The calories are meaningless because they are crudely estimated rather
than directly measured as would be meal weight for those who are using
the 2PD-OMER Approach to eat less down to the optimal amount:

http://HeartMDPhD.com/EatLess

May you and other dear friends, brethren, and neighbors have a
blessedly wonderful New Years ...

... by being hungrier:

http://TruthRUS.org/BeRight

Hunger is wonderful :-)

It's how we know what GOD wants, which is what is good.

Yes, hunger is our knowledge of good versus evil that Adam and Eve
paid for with their and our immortal lives.

However, there are crazy folks, who have rejected this knowledge and
are perishing as predicted by the prophecy of 2 Thessalonians
2:9-11...

http://HeartMDPhD.com/Convicts/CrazyOne

Be hungry... be healthy... be hungrier... be blessed:

http://HeartMDPhD.com/HolySpirit/BeBlessed

"Blessed are you who hunger NOW...

... for you will be satisfied." -- LORD Jesus Christ (Luke 6:21)

Amen.

Prayerfully in the infinite power and might of the Holy Spirit,

Andrew <><
--
Andrew B. Chung, MD/PhD
Lawful steward of http://EmoryCardiology.com
Bondservant to the KING of kings and LORD of lords.
 
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