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Medical Forum / General / Cardiology / August 2007

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Cardiac abnormalities as a new manifestation of nonalcohlic fatty liver disease: ecchocardiographic and tissue doppler imaging assessment.

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DrABO - 26 Aug 2007 22:53 GMT
The authors of this study examined heart function in38
patients with non-alcoholic fatty liver disease(NAFLD) who were<55
y.,had a normal  exercise test, and didn't had  metabolic
syndrome,diabetes,  hypertention,or a body mass  index of>40.Compared
with an age and sex match groop,NAFLD patients had a mild alteration
of left ventricle geometry and early left vent. dysfunction. Goland
S,Shimoni S,Zornitzki T et al. Kaplan Medical Center,Jerusalem,Israel.
J Clin Gastroentrol 2006,40:949-55.
Andrew B. Chung, MD/PhD - 26 Aug 2007 23:12 GMT
> The authors of this study examined heart function in38
> patients with non-alcoholic fatty liver disease(NAFLD) who were<55
> y.,had a normal  exercise test, and didn't had  metabolic
> syndrome

Incorrect.

Folks with NAFLD, which is a manifestation of VAT, essentially have
metabolic syndrome (MetS).

Source:

http://tinyurl.com/24g44o

Nonalcoholic fatty liver disease (NAFLD) is linked to the metabolic
syndrome. The aim of the present study is to determine the effect of
the metabolic syndrome on left ventricular (LV) geometry and function
using as a model patients with NAFLD. Thirty-eight patients with
NAFLD, less than 55 years of age and with a normal exercise test, were
compared with an age and sex-matched control group. Patients with
diabetes mellitus, hypertension, and body mass index>40 were excluded.
A complete echocardiographic study including tissue Doppler imaging
(TDI) was performed. The following parameters were assessed by echo
Doppler: peak velocities of early (E) and late (A) diastolic filling,
E/A ratio, flow propagation velocity (Vp). Using TDI early diastolic
velocity (E'), and systolic velocity (S') of mitral annulus were
obtained. The patients with NAFLD had a significantly higher body mass
index (31.4+/-5 vs. 26.4+/-4 kg/m, P=0.01), higher glucose (100.6+/-13
vs. 83.0+/-10 mg/dL, P=0.01), and triglyceride levels (126.5+/-44 vs.
206.5+/-67 mg/dL, P<0.001). Increased thickness of the
intraventricular septum, posterior wall (11.03+/-2.2 vs. 8.9+/-2.9 mm,
P=0.001; 8.5+/-1.7 vs. 9.7+/-2.3 mm, P=0.04), and larger LV mass and
LV mass/height (160.7+/-58.7 vs.115.3+/-35.4 g, P=0.001 and
92.6+/-29.5 vs. 69.2+/-19.8 g/m, P=0.001, respectively) were found in
NAFLD group. LV systolic function was similar in both groups. Patients
with NAFLD had a lower E (73.6+/-11.0 vs. 86.4+/-20.0 cm/s, P<0.006)
and E/A ratio (1.0+/-0.3 vs. 1.76+/-0.8 P<0.0001). Moreover, the Vp
and the E' on TDI were significantly lower compared with the control
group (49.0+/-9.7 vs. 74.7+/-18.4 cm/s, P<0.0001 and 10.3+/-2.0 vs.
13.8+/-1.7 cm/s, P<0.0001, respectively). On multivariate analysis the
E' on TDI was the only independent parameter associated with NAFLD. In
conclusion, patients with NAFLD in the absence of morbid obesity,
hypertension, and diabetes have mildly altered LV geometry and early
features of left ventricular diastolic dysfunction. Early diastolic
velocity on TDI was found to be the only index that could identify the
patients with NAFLD and metabolic syndrome.

PMID: 17063117 [PubMed - indexed for MEDLINE]

VAT is bad.

Truly, it is only when we are hungry (stomachs singing and
laughing :-) that our bodies get rid of the VAT.

Hunger is wonderful.

GOD should know...

"Blessed are you who hunger NOW for you will be satisfied." -- LORD
Jesus Christ (Luke 6:21)

Amen.

Be hungry... be healthy... be hungrier... be blessed:

http://TheWellnessFoundation.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist
truth@is-better.com - 26 Aug 2007 23:25 GMT
Our atlanta friend obsessed once again:

"VAT is bad.

Truly, it is only when we are hungry (stomachs singing and
laughing :-) that our bodies get rid of the VAT."

Vat is normal and universal to all humans.  It plays a role in normal
energy metabolism as a source of hormones.  You have it this very second
and have had it all your life and will have it until the day you die.
It is vat at greatly higher then normal levels that can pose a problem.

So it is stomach sounds that prompts vat, or not?  Or is it more
accurate to say that hunger and stomach sounds are the tail of the dog
and not the dog?

This bit of sophistry is like saying sun rises cause sun burns.

God bless.
Flying Rat - 26 Aug 2007 23:34 GMT
> Hunger is wonderful.
>
> GOD should know...

as he is issuing new commandments, does that not mean Chung is again
setting himself up as a prophet? The messenger of God?

   "But a prophet who presumes to speak in my name anything I have not
commanded him to say, or a prophet who speaks in the name of other gods,
must be put to death."

   "You may say to yourselves, 'How can we know when a message has not
been spoken by the Lord?' If what a prophet proclaims in the name of the
Lord does not take place or come true, that is a message the Lord has
not spoken. That prophet has spoken presumptuously. Do not be afraid of
him" (Deuteronomy 18:20-22 NIV).

So as Chung prophesied earthquakes, nuclear wars, the destruction of
Tehran (complete with dates) and the rest, that qualifies him firmly as
a false prophet. No doubt his St Chung the Baptist fantasy will continue
unabated.

FR
 
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