Medical Forum / General / Cardiology / July 2007
Is water more effective than statins in preventing heart disease mortality?
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Juhana Harju - 30 Jul 2007 11:14 GMT If patients were adviced to drink at least 5 glasses of water per day would that reduce heart disease mortality more than statin medication?
http://aje.oxfordjournals.org/cgi/reprint/155/9/827.pdf
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Andrew B. Chung, MD/PhD - 30 Jul 2007 12:00 GMT > If patients were adviced to drink at least 5 glasses of water per day would > that reduce heart disease mortality more than statin medication? > > http://aje.oxfordjournals.org/cgi/reprint/155/9/827.pdf It is likely that folks who are drinking 5 or more glasses of water per day instead of non-water beverages are more health conscious overall and that the latter behavior is what has resulted in a reduction in CVD for these Seventh Day Adventists.
Be hungry... be healthy... be blessed:
http://HeartMDPhD.com/PressRelease
Prayerfully in Jesus' awesome love,
Andrew <>< -- Andrew B. Chung, MD/PhD Cardiologist
Andy is Evil - 30 Jul 2007 13:46 GMT >> If patients were adviced to drink at least 5 glasses of water per day >> would that reduce heart disease mortality more than statin medication? [quoted text clipped - 5 lines] > overall and that the latter behavior is what has resulted in a > reduction in CVD for these Seventh Day Adventists. From the study itself: Our study has strengths and limitations. As an observational study, potential confounding always needs to be considered. Could fluid consumption be a marker of other risk factors not included in the model? Few candidate confounding variables are obvious. Those subjects who drink more water may be more health conscious in other less clearly defined ways. Drinking more water may be a marker of higher physical activity or those with higher energy intake. However, a two-tailed Pearson’s correlation test showed no correlation between water and energy intakes (r 0.08, p < 0.01 and r 0.06, p < 0.01 for males and females, respectively) and, when exercise and energy consumption are included in the multivariate model, the effect of water consumption remained.
> Be hungry... be healthy... be blessed: > > http://HeartMDPhD.com/PressRelease SCAM ALERT SPAM SITE
Still waiting for the peer review of the 2PD "approach".
Andy is Evil
MarilynMann - 30 Jul 2007 13:46 GMT > If patients were adviced to drink at least 5 glasses of water per day would > that reduce heart disease mortality more than statin medication? [quoted text clipped - 3 lines] > -- > Juhana This study would seem to be hypothesis-generating at best. Have you looked to see if anything else has been done on this?
Marilyn
Juhana Harju - 30 Jul 2007 15:53 GMT >> If patients were adviced to drink at least 5 glasses of water per >> day would that reduce heart disease mortality more than statin [quoted text clipped - 3 lines] >> > This study would seem to be hypothesis-generating at best. Sure. But the study gave a legitimate reason to ask a polemical question.
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William Wagner - 30 Jul 2007 16:47 GMT > >> If patients were adviced to drink at least 5 glasses of water per > >> day would that reduce heart disease mortality more than statin [quoted text clipped - 5 lines] > > Sure. But the study gave a legitimate reason to ask a polemical question. Sorry I misspelled your name in a recent post.
Bill
This viscosity or SPG aka Specific gravity idea sorts of resonates with me as it very physical and less chemical in nature way of looking at health issue. Years ago working in a chemical factory when having to give urine samples the scuttle butt was the less bubbles the better.
Meanwhile what is a good Specific gravity of blood for most folks?
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MarilynMann - 30 Jul 2007 18:17 GMT Whether high blood viscosity is a bad thing and whether drinking 5 glasses of water a day lowers blood viscosity are two different questions. There have been a couple of studies where having people drink more water didn't really have much of an effect on blood viscosity, except for transient effects.
As Jim said, it would be pretty hard to do a study with clinical endpoints. I don't see how you could blind the participants, for one thing. Also, you would likely have big problems getting people to stick to the treatment. You would end up with the treatment and control groups drinking pretty close to the same amount of water.
Not that I am claiming to know much about the issues.
Marilyn
MarilynMann - 30 Jul 2007 18:30 GMT International Journal of Urology Volume 14 Issue 5 Page 470-472, May 2007
To cite this article: Kimio Sugaya, Saori Nishijima, Masami Oda, Minoru Miyazato, Yoshihide Ogawa (2007) Change of blood viscosity and urinary frequency by high water intake International Journal of Urology 14 (5), 470-472.
Abstract Short Communication Change of blood viscosity and urinary frequency by high water intake Kimio Sugaya , Saori Nishijima , Masami Oda , Minoru Miyazato and Yoshihide Ogawa Division of Urology, Department of Organ-oriented Medicine, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan Kimio Sugaya md phd, Division of Urology, Department of Organ-oriented Medicine, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan. Email: sugaya@med.u-ryukyu.ac.jp Abstract Abstract: Physicians recommend a high water intake to prevent cerebral infarction by decreasing blood viscosity. However, there is no evidence that high water intake decreases viscosity, although it increases urinary frequency. Therefore, we investigated the change of blood viscosity and urinary frequency by high water intake. We examined the change of blood viscosity after acute water intake, the circadian rhythm of blood viscosity, and the change of early morning blood viscosity and urinary frequency after high water intake for 1 week in healthy volunteers aged 31-75 years. Blood viscosity decreased transiently by acute water intake, but remained within the range of its circadian rhythm. Morning blood viscosity did not alter by high water intake for 1 week, although urinary frequency increased. Because excessive water intake increases urinary frequency without decreasing blood viscosity, a high water intake should not be recommended in persons with urinary frequency.
Jim Chinnis - 30 Jul 2007 19:58 GMT MarilynMann <mannm@comcast.net> wrote in part:
>International Journal of Urology >Volume 14 Issue 5 Page 470-472, May 2007 [quoted text clipped - 30 lines] >blood viscosity, a high water intake should not be recommended in >persons with urinary frequency. Good find! -- Jim Chinnis Warrenton, Virginia, USA
William Wagner - 30 Jul 2007 20:38 GMT Blood spg looks like it should be like water 1.0000 to me.
Bill whose blood is thicker by eye.
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http://www.clinchem.org/cgi/content/abstract/20/5/615
Clinical Chemistry 20: 615-616, 1974;
Articles by Trudnowski, R. J.
Articles by Rico, R. C.
Clinical Chemistry, Vol 20, 615-616, Copyright (C) 1974 by the American Association for Clinical Chemistry Specific Gravity of Blood and Plasma at 4 and 37 ?C Raymond J. Trudnowski 1 and Rodolfo C. Rico 1 1 Department of Anesthesiology, Roswell Park Memorial Institute, New York State Department of Health, 666 Elm St., Buffalo, N. Y. 14203.
The specific gravity (relative density) of human whole blood and plasma from 25 healthy volunteers was determined gravimetrically. For whole blood it was found to be 1.0621 (95% confidence interval: 1.0652-1.0590) at 4 ?C and 1.0506 (95% confidence interval: 1.0537-1.0475) at 37 ?C. Plasma specific gravity was 1.0310 (95% confidence interval: 1.0324-1.0296) at 4 ?C and 1.0205 (95% confidence interval: 1.0216-1.0193) at 37 ?C. All of these values are referred to the density of water at 4 ?C. We show the relationship between these values and those given in the literature for measurements at 25 ?C. There was a small increase in whole blood specific gravity with increasing hematocrit, but it was not statistically significant over the 40-56 hematocrit range studied.
Submitted on January 28, 1974 Accepted on February 25, 1974
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Don Kirkman - 31 Jul 2007 00:05 GMT It seems to me I heard somewhere that Jim Chinnis wrote in article <d6dsa3503p4beaa46ie2spm1fltio0thea@4ax.com>:
>MarilynMann <mannm@comcast.net> wrote in part:
>>International Journal of Urology >>Volume 14 Issue 5 Page 470-472, May 2007
>>To cite this article: Kimio Sugaya, Saori Nishijima, Masami Oda, >>Minoru Miyazato, Yoshihide Ogawa (2007) >>Change of blood viscosity and urinary frequency by high water intake >>International Journal of Urology 14 (5), 470-472.
>>Abstract >>Short Communication [quoted text clipped - 22 lines] >>blood viscosity, a high water intake should not be recommended in >>persons with urinary frequency.
>Good find! As an anecdotal addendum to this, physical trainers have fairly recently come to recognize that distance runners may over-hydrate during long runs (particularly marathons or longer), thus inducing hyponatremia with sometimes serious results. They are beginning to advise caution about the rote runner's advice to drink fluids at every opportunity during a run.
 Signature Don Kirkman
Jim Chinnis - 30 Jul 2007 16:15 GMT MarilynMann <mannm@comcast.net> wrote in part:
>> If patients were adviced to drink at least 5 glasses of water per day would >> that reduce heart disease mortality more than statin medication? [quoted text clipped - 8 lines] > >Marilyn I agree. Unfortunately, the research is very hard to do. At best, a randomized trial might be done with animals... -- Jim Chinnis Warrenton, Virginia, USA
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