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Medical Forum / General / Cardiology / July 2007

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Is water more effective than statins in preventing heart disease mortality?

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Juhana Harju - 30 Jul 2007 11:14 GMT
If patients were adviced to drink at least 5 glasses of water per day would
that reduce heart disease mortality more than statin medication?

http://aje.oxfordjournals.org/cgi/reprint/155/9/827.pdf

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Juhana

Andrew B. Chung, MD/PhD - 30 Jul 2007 12:00 GMT
> If patients were adviced to drink at least 5 glasses of water per day would
> that reduce heart disease mortality more than statin medication?
>
> http://aje.oxfordjournals.org/cgi/reprint/155/9/827.pdf

It is likely that folks who are drinking 5 or more glasses of water
per day instead of non-water beverages are more health conscious
overall and that the latter behavior is what has resulted in a
reduction in CVD for these Seventh Day Adventists.

Be hungry... be healthy... be blessed:

http://HeartMDPhD.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist
Andy is Evil - 30 Jul 2007 13:46 GMT
>> If patients were adviced to drink at least 5 glasses of water per day
>> would that reduce heart disease mortality more than statin medication?
[quoted text clipped - 5 lines]
> overall and that the latter behavior is what has resulted in a
> reduction in CVD for these Seventh Day Adventists.

From the study itself:
Our study has strengths and limitations. As an observational
study, potential confounding always needs to be considered.
Could fluid consumption be a marker of other risk
factors not included in the model? Few candidate confounding
variables are obvious. Those subjects who drink more
water may be more health conscious in other less clearly
defined ways. Drinking more water may be a marker of
higher physical activity or those with higher energy intake.
However, a two-tailed Pearson’s correlation test showed no
correlation between water and energy intakes (r  0.08, p <
0.01 and r  0.06, p < 0.01 for males and females, respectively)
and, when exercise and energy consumption are
included in the multivariate model, the effect of water consumption
remained.

> Be hungry... be healthy... be blessed:
>
> http://HeartMDPhD.com/PressRelease
SCAM ALERT
SPAM SITE

Still waiting for the peer review of the 2PD "approach".

Andy is Evil
MarilynMann - 30 Jul 2007 13:46 GMT
> If patients were adviced to drink at least 5 glasses of water per day would
> that reduce heart disease mortality more than statin medication?
[quoted text clipped - 3 lines]
> --
> Juhana

This study would seem to be hypothesis-generating at best.  Have you
looked to see if anything else has been done on this?

Marilyn
Juhana Harju - 30 Jul 2007 15:53 GMT
>> If patients were adviced to drink at least 5 glasses of water per
>> day would that reduce heart disease mortality more than statin
[quoted text clipped - 3 lines]
>>
> This study would seem to be hypothesis-generating at best.  

Sure. But the study gave a legitimate reason to ask a polemical question.

Signature

Juhana

William Wagner - 30 Jul 2007 16:47 GMT
> >> If patients were adviced to drink at least 5 glasses of water per
> >> day would that reduce heart disease mortality more than statin
[quoted text clipped - 5 lines]
>
> Sure. But the study gave a legitimate reason to ask a polemical question.

Sorry I misspelled  your name in a recent post.

Bill

This viscosity  or SPG aka Specific gravity  idea sorts of resonates
with me as it very physical and less chemical in nature way of looking
at health issue.   Years ago working in a chemical factory when having
to give urine samples the scuttle butt was the less bubbles the better.

Meanwhile what is a good Specific gravity of blood for most folks?

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S Jersey USA Zone 5 Shade  
http://www.ocutech.com/  High tech Vison aid
This article is posted under fair use rules in accordance with
Title 17 U.S.C. Section 107, and is strictly for the educational
and informative purposes. This material is distributed without profit.

MarilynMann - 30 Jul 2007 18:17 GMT
Whether high blood viscosity is a bad thing and whether drinking 5
glasses of water a day lowers blood viscosity are two different
questions.  There have been a couple of studies where having people
drink more water didn't really have much of an effect on blood
viscosity, except for transient effects.

As Jim said, it would be pretty hard to do a study with clinical
endpoints.  I don't see how you could blind the participants, for one
thing.  Also, you would likely have big problems getting people to
stick to the treatment.  You would end up with the treatment and
control groups drinking pretty close to the same amount of water.

Not that I am claiming to know much about the issues.

Marilyn
MarilynMann - 30 Jul 2007 18:30 GMT
International Journal of Urology
Volume 14 Issue 5 Page 470-472, May 2007

To cite this article: Kimio Sugaya, Saori Nishijima, Masami Oda,
Minoru Miyazato, Yoshihide Ogawa (2007)
Change of blood viscosity and urinary frequency by high water intake
International Journal of Urology 14 (5), 470-472.

Abstract
Short Communication
Change of blood viscosity and urinary frequency by high water intake
Kimio Sugaya , Saori Nishijima , Masami Oda , Minoru Miyazato and
Yoshihide Ogawa Division of Urology, Department of Organ-oriented
Medicine, Faculty of Medicine, University of the Ryukyus, Okinawa,
Japan
Kimio Sugaya md phd, Division of Urology, Department of Organ-oriented
Medicine, Faculty of Medicine, University of the Ryukyus, 207 Uehara,
Nishihara, Okinawa 903-0215, Japan. Email: sugaya@med.u-ryukyu.ac.jp
Abstract
Abstract:  Physicians recommend a high water intake to prevent
cerebral infarction by decreasing blood viscosity. However, there is
no evidence that high water intake decreases viscosity, although it
increases urinary frequency. Therefore, we investigated the change of
blood viscosity and urinary frequency by high water intake. We
examined the change of blood viscosity after acute water intake, the
circadian rhythm of blood viscosity, and the change of early morning
blood viscosity and urinary frequency after high water intake for 1
week in healthy volunteers aged 31-75 years. Blood viscosity decreased
transiently by acute water intake, but remained within the range of
its circadian rhythm. Morning blood viscosity did not alter by high
water intake for 1 week, although urinary frequency increased. Because
excessive water intake increases urinary frequency without decreasing
blood viscosity, a high water intake should not be recommended in
persons with urinary frequency.
Jim Chinnis - 30 Jul 2007 19:58 GMT
MarilynMann <mannm@comcast.net> wrote in part:

>International Journal of Urology
>Volume 14 Issue 5 Page 470-472, May 2007
[quoted text clipped - 30 lines]
>blood viscosity, a high water intake should not be recommended in
>persons with urinary frequency.

Good find!
--
Jim Chinnis   Warrenton, Virginia, USA
William Wagner - 30 Jul 2007 20:38 GMT
Blood spg looks like it should be like water 1.0000 to me.

Bill whose blood is thicker by eye.

.....................

http://www.clinchem.org/cgi/content/abstract/20/5/615

Clinical Chemistry 20: 615-616, 1974;

Articles by Trudnowski, R. J.

Articles by Rico, R. C.

Clinical Chemistry, Vol 20, 615-616, Copyright (C) 1974 by the American
Association for Clinical Chemistry
Specific Gravity of Blood and Plasma at 4 and 37 ?C
Raymond J. Trudnowski 1 and Rodolfo C. Rico 1
1 Department of Anesthesiology, Roswell Park Memorial Institute, New
York State Department of Health, 666 Elm St., Buffalo, N. Y. 14203.

The specific gravity (relative density) of human whole blood and plasma
from 25 healthy volunteers was determined gravimetrically. For whole
blood it was found to be 1.0621 (95% confidence interval: 1.0652-1.0590)
at 4 ?C and 1.0506 (95% confidence interval: 1.0537-1.0475) at 37 ?C.
Plasma specific gravity was 1.0310 (95% confidence interval:
1.0324-1.0296) at 4 ?C and 1.0205 (95% confidence interval:
1.0216-1.0193) at 37 ?C. All of these values are referred to the density
of water at 4 ?C. We show the relationship between these values and
those given in the literature for measurements at 25 ?C. There was a
small increase in whole blood specific gravity with increasing
hematocrit, but it was not statistically significant over the 40-56
hematocrit range studied.

Submitted on January 28, 1974
Accepted on February 25, 1974

Signature

S Jersey USA Zone 5 Shade  
http://www.ocutech.com/  High tech Vison aid
This article is posted under fair use rules in accordance with
Title 17 U.S.C. Section 107, and is strictly for the educational
and informative purposes. This material is distributed without profit.

Don Kirkman - 31 Jul 2007 00:05 GMT
It seems to me I heard somewhere that Jim Chinnis wrote in article
<d6dsa3503p4beaa46ie2spm1fltio0thea@4ax.com>:

>MarilynMann <mannm@comcast.net> wrote in part:

>>International Journal of Urology
>>Volume 14 Issue 5 Page 470-472, May 2007

>>To cite this article: Kimio Sugaya, Saori Nishijima, Masami Oda,
>>Minoru Miyazato, Yoshihide Ogawa (2007)
>>Change of blood viscosity and urinary frequency by high water intake
>>International Journal of Urology 14 (5), 470-472.

>>Abstract
>>Short Communication
[quoted text clipped - 22 lines]
>>blood viscosity, a high water intake should not be recommended in
>>persons with urinary frequency.

>Good find!

As an anecdotal addendum to this, physical trainers have fairly recently
come to recognize that distance runners may over-hydrate during long
runs (particularly marathons or longer), thus inducing hyponatremia with
sometimes serious results.  They are beginning to advise caution about
the rote runner's advice to drink fluids at every opportunity during a
run.
Signature

Don Kirkman

Jim Chinnis - 30 Jul 2007 16:15 GMT
MarilynMann <mannm@comcast.net> wrote in part:

>> If patients were adviced to drink at least 5 glasses of water per day would
>> that reduce heart disease mortality more than statin medication?
[quoted text clipped - 8 lines]
>
>Marilyn

I agree. Unfortunately, the research is very hard to do. At best, a
randomized trial might be done with animals...
--
Jim Chinnis   Warrenton, Virginia, USA
 
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