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Medical Forum / General / Cardiology / June 2007

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Sub clinical Cushing's syndrome

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Susan - 29 Jun 2007 19:59 GMT
http://www.csrf.net/Articles2.htm#Treatment

"What populations are most likely to have subclinical Cushing's syndrome?
One might look for SCS in two main patient populations with the
expectation that making this diagnosis would lead to a beneficial
therapeutic intervention: 1) patients with an incidentally discovered
tumor that may inappropriately secrete cortisol (adrenal gland) or ACTH
(pituitary gland). Usually these lesions are called incidentalomas. 2)
patients that display non-specific pathologies that may be secondary to
hypercortisolism such as obesity, diabetes, hypertension, osteoporosis
etc.."

Susan
tauzinger - 29 Jun 2007 20:15 GMT
> x-no-archive: yes
>
[quoted text clipped - 11 lines]
>
> Susan

http://endocrine.niddk.nih.gov/pubs/cushings/cushings.htm
says "10-15 million a year", but it doesn't say if this is US or
worldwide.

http://en.wikipedia.org/wiki/Cushing's_syndrome
"Incidence of causes of Cushing's syndrome per million person-years:

   * Cushing's disease: 10
   * Primary adrenal: 3
   * Ectopic ACTH: 1.4"

Thanks,

Thomas
http://ecg.auzinger.org
Susan - 29 Jun 2007 20:52 GMT
>>x-no-archive: yes
>>
[quoted text clipped - 27 lines]
> Thomas
> http://ecg.auzinger.org

Considering how difficult it is for even the most florid cases to be
taken seriously and diagnosed, multiplying that by 10 probably wouldn't
be enough.

Susan
 
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