1: Herz. 2006 Dec;31 Suppl 3:24-30. Links
Prevention of cardiovascular diseases and highly concentrated n-3
polyunsaturated fatty acids (PUFAs).
Weber HS , Selimi D , Huber G.

30 years ago the observation of a lower incidence of cardiovascular
diseases in Inuits (Eskimos) was related to the higher fish
consumption when compared to the residual Danish population. Clinical
studies confirmed this finding. It was explained by the higher content
of polyunsaturated fatty acids (PUFA) in fish, especially of omega-3
PUFAs. Experimental studies in cell cultures and also in animals with
and without infarction models verified the anti-arrhythmic effect of
omega-3 PUFAs among other possible contributing factors when compared
to other fatty acids. In clinical studies a significant reduction (ca.
40%) of sudden cardiac deaths (SCD) could be found in patients after
an acute myocardial infarction, if they were treated with at least 1 g
omega-3 PUFAs daily, either by consumption of fish twice weekly or of
a highly purified preparation omega-3 PUFAs in capsules. These
findings led to recommendations of the American Heart Association and
the European Society of Cardiology to a higher fish consumption and/or
the daily intake of 1 g omega-3 PUFAs for primary and especially for
secondary prevention of cardiovascular diseases. The much fewer side-
effects, and the standardised dosage on one hand and the negative
effect of the sometimes higher mercury content of fish make the intake
of omega-3 PUFAs as capsules the better choice.

Perhaps a better sales force?  Thanks Vince
PMID: 17575803 [PubMed - in process]
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