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Medical Forum / General / Cardiology / January 2007

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Stress Echo Results

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mtstreet@mchsi.dot.com - 21 Jan 2007 00:24 GMT
I had aortic valve replacement and aneurysm repair in 1999 - take
coumadin, Tegretol (for complex partial seizures) and Crestor.

I was sent for a stress echo last week following two episodes of near
syncope, which my primary care doctor said was probably vasovagal
syncope. I have been dealing with some pretty bad fatigue for over a
year now but all blood work is fine.  Cholesterol is slightly elevated
but my "good cholesterol" is 105. I check my BP on ocassion and it's
almost always fine.  

The first part of the echo was normal, though the doctor noted
"borderline left atrium enlargement."  I was confused by this as the
LA measurement was 3.1 and normal size should be less than 4.0.  The
doctor also commented that there was "no evidence of exercise induced
myocardial ischemia."  

The treadmill part, however, noted this abnormality: "Patient reached
adequate heart rate. She developed 0.5mm horizontal ST depression and
T-wave inversion in leads II,III,aVF and V4,5,6. In these leads there
is baseline ST/T abnormality."

I understand that a diagnosis can't be given over the net but nothing
was really explained to me about what this meant and I can't get an
appointment to see the cardio until late next month.  Can someone tell
me what this might mean?  Everything else looked so good I don't
understand why the doctor concluded that the test was "abnormal."

Thanks in advance for any info.
Andrew B. Chung, MD/PhD - 21 Jan 2007 01:01 GMT
> I had aortic valve replacement and aneurysm repair in 1999 - take
> coumadin, Tegretol (for complex partial seizures) and Crestor.
[quoted text clipped - 9 lines]
> "borderline left atrium enlargement."  I was confused by this as the
> LA measurement was 3.1 and normal size should be less than 4.0.

It is possible that by the cardiologist's eye your left atrium looked
bigger than what the tech measured.

> The
> doctor also commented that there was "no evidence of exercise induced
> myocardial ischemia."

That should be reassuring.

> The treadmill part, however, noted this abnormality: "Patient reached
> adequate heart rate. She developed 0.5mm horizontal ST depression and
> T-wave inversion in leads II,III,aVF and V4,5,6. In these leads there
> is baseline ST/T abnormality."

This suggests that there might be some ischemia.

> I understand that a diagnosis can't be given over the net but nothing
> was really explained to me about what this meant and I can't get an
> appointment to see the cardio until late next month.  Can someone tell
> me what this might mean?  Everything else looked so good I don't
> understand why the doctor concluded that the test was "abnormal."

The EKG part was abnormal.

> Thanks in advance for any info.

You are welcome.

Andrew <><
--
Andrew B. Chung, MD/PhD
http://EmoryCardiology.com
mtstreet@mchsi.dot.com - 21 Jan 2007 01:51 GMT
>> The treadmill part, however, noted this abnormality: "Patient reached
>> adequate heart rate. She developed 0.5mm horizontal ST depression and
[quoted text clipped - 10 lines]
>
>The EKG part was abnormal.

Thanks for the info. What is the chance of a stress test being wrong?
I do have a mechanical aortic valve and wonder if that could be a
factor in this showing up as abnormal. However, with the fatigue and
weakness I've been feeling ischemia would somehow make sense.
However, there are a billion causes for fatigue.

Thanks again.
Andrew B. Chung, MD/PhD - 21 Jan 2007 01:57 GMT
neighbor mtstr...@mchsi.dot.com wrote:
> Andrew, in the Holy Spirit, boldly wrote:
>
[quoted text clipped - 14 lines]
>
> Thanks for the info.

You are welcome :-)

> What is the chance of a stress test being wrong?

There is a possibility.  Determining how probable would require knowing
the rest of your history and examining you.

> I do have a mechanical aortic valve and wonder if that could be a
> factor in this showing up as abnormal.

It would not cause the change with exercise stress.

> However, with the fatigue and
> weakness I've been feeling ischemia would somehow make sense.
> However, there are a billion causes for fatigue.

Medicine remains an art.

> Thanks again.

Again, you are welcome.

Andrew <><
--
Andrew B. Chung, MD/PhD
http://EmoryCardiology.com
Port@nospam.invalid - 21 Jan 2007 15:13 GMT
mtstreet wrote:
>What is the chance of a stress test being wrong?

I'm not a doctor. But here's my experience.
When my Angina symptoms appeared (classic textbook symptoms I might
add), my Primary doc did an EKG, which was normal, but sent me to a
Cardiologist anyway. The Cardio guy did a Stress Echo which turned out
completely "Normal".  I asked for a Cath but, due to the S/E test
results plus my complete lack of "CVD risk factors", I was advised
against it.  I got a second opinion (2nd Cardiologist) which agreed
with the first and was told that the Stress Echo was 98% accurate and,
in my case, there was no question that my pain had to be muscular or
skeletal and definitely NOT heart related. The advice from all three
docs (Primary & 2 Cardiologists) was to maintain my lifestyle running,
biking, etc and I'd never have to worry about heart probs. So for
three years, that's what I did, ignoring the pain (and asking for a
Cath at each annual Physical).

Finally, after a 30 mile bike ride in May '05, I couldn't take it any
more. I went to my Primary guy and deMANded a Cath. He did an EKG that
was a little "different" than before and sent me to a 3rd Cardiologist
who, after much arm twisting, agreed to do the Cath. That Cath showed
up numerous blockages and resulted in a CABGx5 the next day.

A few days later, in the hospital hallway, I bumped into my Primary
Physician. He was pretty sheepish and his first words were "Well,
that's the last time I'll trust one of those damn Stress Echos".  LoL!

Moral of the story: A Stress Echo CAN be wrong.  If you feel in your
gut something's not right, stay on your doc's butt until you get an
answer that makes sense to YOU. Just remember, NObody is as concerned
about your health as YOU are.

Port
Andrew B. Chung, MD/PhD - 21 Jan 2007 16:00 GMT
> mtstreet wrote:
> >What is the chance of a stress test being wrong?
[quoted text clipped - 30 lines]
>
> Port

Actually, the moral to your story is that neither athleticism nor being
physical fit will keep you from developing occlusive coronary disease.

However, eating the optimal amount thereby staying optimally healthy
sans VAT will prevent CV disease:

http://groups.google.com/group/sci.med.cardiology/msg/352546a7bf4a81ee?

Andrew <><
--
Andrew B. Chung, MD/PhD
http://EmoryCardiology.com
mtstreet@mchsi.dot.com - 21 Jan 2007 17:22 GMT
> mtstreet wrote:
>>What is the chance of a stress test being wrong

>Moral of the story: A Stress Echo CAN be wrong.  If you feel in your
>gut something's not right, stay on your doc's butt until you get an
>answer that makes sense to YOU. Just remember, NObody is as concerned
>about your health as YOU are.
>
>Port

My gut feeling is indeed that something's wrong.  However, the main
symptom I'm having is bad fatigue, which can also be caused by any
number of non-cardiac reasons. I don't show any signs of a blood sugar
or thyroid problem, though.

Still, fatigue was the only reason I went to the doctor back in 1999
and I ended up with aortic valve replacement/aneurysm repair just
three or four months later. I had no idea anything was wrong.  Since
I'm dealing with fatigue again I immediately worry that something's
wrong with my heart.  I do get SOB every so often but that might be an
allergy I'm unaware of or sinus problems.  

I walk every day so yeah, just because you keep active doesn't mean
that your heart is going to be fine.

Anyway, I'm determined to get to the bottom of this.

Cheers!
William Wagner - 21 Jan 2007 18:00 GMT
>  fatigue

Myopathy is the most common side effect with symptoms ranging from
fatigue, weakness, and pain to symptoms associated with rhabdomyolysis
which is a life-threatening condition.

.........................

1: Am J Physiol Cell Physiol. 2006 Dec;291(6):C1208-12. Epub 2006 Aug 2.
 Links
Statin-induced apoptosis and skeletal myopathy.
  ?  Dirks AJ, Jones KM.
Wingate University School of Pharmacy, Wingate, North Carolina 28174,
USA. adirks@wingate.edu
Over 100 million prescriptions were filled for statins
(3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) in 2004.
Statins were originally developed to lower plasma cholesterol in
patients with hypercholesterolemia and are the most effective drugs on
the market in doing so. Because of the discovered pleiotropic effects of
statins, the use has expanded to the treatment of many other conditions,
including ventricular arrythmias, idiopathic dilated cardiomyopathy,
cancer, osteoporosis, and diabetes. The elderly population is growing.
Therefore, it is estimated that the number of statin users will also
increase. Fortunately, the use of statins is relatively safe with few
side effects. Myopathy is the most common side effect with symptoms
ranging from fatigue, weakness, and pain to symptoms associated with
rhabdomyolysis which is a life-threatening condition. The development of
statin-induced rhabdomyolysis is rare occurring in approximately 0.1% of
patients; however, the occurrence of less severe symptoms is
underreported and may be 1-5% or more. Physical exercise appears to
increase the likelihood for the development of myopathy in patients
taking statins. It is thought that as many as 25% of statin users who
exercise may experience muscle fatigue, weakness, aches, and cramping
due to statin therapy and potentially dismissed by the patient and
physician. The mechanisms causing statin-induced myopathy have not been
elucidated; however, research efforts suggest that apoptosis of
myofibers may contribute. The mitochondrion is considered a regulatory
center of apoptosis, and therefore its role in the induction of
apoptosis will be discussed as well as the mechanism of statin-induced
apoptosis and myopathy.
PMID: 16885396 [PubMed - in process]

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Andrew B. Chung, MD/PhD - 21 Jan 2007 18:44 GMT
> > neighbor mtstreet wrote:
>
[quoted text clipped - 23 lines]
>
> Anyway, I'm determined to get to the bottom of this.

You will be in my prayers.

Andrew <><
--
Andrew B. Chung, MD/PhD
http://EmoryCardiology.com
caged - 21 Jan 2007 19:28 GMT
Andrew B. Chung, MD/PhD felt the need to share this:

>> Anyway, I'm determined to get to the bottom of this.
>
> You will be in my prayers.

Mine too: Oh Jesus, you smelly old hippie, stop twisting your hair and
gazing at nude men for a few seconds and come help out this guy with a bad
heart.  Take all his problems and give them to Chung.  Nobody cares if
Chung has a bad heart.  After all, he's a cardiologist so he can just fix
his problems himself, right?  Right.  Thanks Jesus.  You f.cking suck, but
we'd never say that to your face because we love you.  Amen.
Father Haskell - 21 Jan 2007 21:12 GMT
> Andrew B. Chung, MD/PhD felt the need to share this:
>
[quoted text clipped - 7 lines]
> Chung has a bad heart.  After all, he's a cardiologist so he can just fix
> his problems himself, right?  Right.

He'll use a kitten as a stent, and everything will be just fine.

> Thanks Jesus.  You f.cking suck, but
> we'd never say that to your face because we love you.  Amen.

I would.  If there WAS a jesus.
WhewAustralopithicus - 21 Jan 2007 21:27 GMT
>> Andrew B. Chung, MD/PhD felt the need to share this:
>>
[quoted text clipped - 15 lines]
>
> I would.  If there WAS a jesus.

Does the jesus soap on a rope count?
 
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