 |
 | Home | Contact Us | FAQ | Search & Site Map | Link to Us |
 | Sign In | Join | Other 45 Sites in Network |
Medical Forum / General / Cardiology / November 2006Sugar cane extract doesn't lower cholesterol
NEW YORK (Reuters Health) - A new study adds to growing evidence that an extract from Cuban sugar cane does not help lower cholesterol levels. A number of plant products work well for cutting cholesterol, such as plant sterols used in margarine and other foods, Dr. Peter J. H. Jones, Canada Research Chair in Nutrition and Functional Foods at the University of Manitoba, Winnipeg, told Reuters Health. But it looks increasingly as if Cuban sugar cane "policosanols" are not one of these products, he said. Jones and his colleague, Dr. Amira N. Kassis, had 21 healthy men and women with high cholesterol eat 10 milligrams of policosanols daily or a placebo for 28 days. After an additional 28-day "washout period," the study participants were switched to placebo or policosanols. Jones and Kassis found no effect of the policosanols on any measure of participants' cholesterol. While dozens of human and animal studies from one lab based in Cuba have shown dramatic cholesterol-lowering effects approaching those of statins for policosanols, studies done elsewhere have shown no effect, the researchers note in their report in the American Journal of Clinical Nutrition. Proponents have suggested that perhaps only Cuban sugar cane extracts will work, but Jones and Kassis used the same type employed by the Cuban lab, as have other researchers recently, without seeing results. It remains remotely possible that Cuban individuals have some sort of genetic difference that makes them react differently to policosanols, or that they eat so many policosanols in their normal diet that supplementation with the extract has more of an effect than it would in other people, Jones said. The current study, Jones said, underscores the need for more scrutiny of herbal product claims. The policosanol extract, he noted, is being sold for a dollar a pill around the world. SOURCE: American Journal of Clinical Nutrition, November 2006. : NEW YORK (Reuters Health) - A new study adds to growing evidence that : an extract from Cuban sugar cane does not help lower cholesterol [quoted text clipped - 15 lines] : Jones and Kassis found no effect of the policosanols on any measure of : participants' cholesterol. It is possible that the trial time is was too short. "Studies generally found that it can take up to two months to notice benefits." http://altmedicine.about.com/od/policosanol/a/policosanol.htm# : While dozens of human and animal studies from one lab based in Cuba : have shown dramatic cholesterol-lowering effects approaching those of [quoted text clipped - 17 lines] : : SOURCE: American Journal of Clinical Nutrition, November 2006. It is possible that the trial time is was too short. I have read that it can take two months before the effect of policosanol is seen.  SignatureJuhana >: NEW YORK (Reuters Health) - A new study adds to growing evidence that >: an extract from Cuban sugar cane does not help lower cholesterol [quoted text clipped - 45 lines] > It is possible that the trial time is was too short. I have read that it can > take two months before the effect of policosanol is seen. I tried it for 8 weeks with no effect. With all talk around here that statin studies are bogus because they may be pharma funded you would think that this comment (from your link) screams "case closed": "...almost all of the 80+ double-blind studies on sugarcane policosanol were conducted by a single research group in Cuba that owns the policosanol patent." L. > I tried it for 8 weeks with no effect. I know lots of folks who've tried it with no effect. Susan > > I tried it for 8 weeks with no effect. > > I know lots of folks who've tried it with no effect. In my clinical experience, policosanol will not work in folks who are overeating. My guess is that there are less folks overeating in Cuba than at the other centers where policosanol has been studied. May GOD continue to help us with our needs, dear neighbor Susan whom I love unconditionally. Prayerfully in Christ's amazing love, Andrew <>< -- Andrew B. Chung Cardiologist, Atlanta, Georgia, USA http://HeartMDPhD.com/HolySpirit As for knowing who are the very elect, these you will know by the unconditional love they have for everyone including their enemies (Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17). http://HeartMDPhD.com/Love "In my clinical experience, policosanol will not work in folks who are overeating. My guess is that there are less folks overeating in Cuba than at the other centers where policosanol has been studied." Do a medline for: "Long-term effects of policosanol on obese patients with Type II Hypercholesterolemia." Once again we find confirmation of a poor grasp of current literature, a non-scientific driven agenda which distorts the discussion, and a continuing reason to safely ignore the source because the truth is not in it. > "In my clinical experience, policosanol will not work in folks who are > overeating. [quoted text clipped - 6 lines] > "Long-term effects of policosanol on obese patients with Type II > Hypercholesterolemia." http://tinyurl.com/yh2ug6 Here's the abstract: Both hypercholesterolemia (HC) and obesity are coronary risk factors. Clinical studies have shown the benefits of lowering elevated plasma levels of low-density lipoprotein-cholesterol (LDL-C) on clinical end-points. Policosanol is a cholesterol-lowering drug purified from sugar cane wax with a therapeutic range from 5 to 20 mg/day. This randomised, double-blinded, placebo-controlled study was undertaken to investigate the long-term efficacy and safety of policosanol in obese patients (BMI>or =30) with Type II hypercholesterolemia. After 5 weeks on step one cholesterol-lowering diet, 129 patients were randomised to policosanol 5 mg or placebo tablets taken once daily with the evening meal for 3 years. Lipid profile variables, safety indicators, adverse events (AE) and compliance with diet counselling and study medications were assessed. Study patiens showed a high frequency of other coronary risk factors, hypertension being the most common. Both groups were well matched at randomisation. After one year on treatment, policosanol significantly (p < 0.01 vs placebo) lowered serum LDL-C, the primary efficacy variable (24.3 %) and total cholesterol (TC) (15.8 %), whereas increased high-density lipoprotein-cholesterol (HDL-C) (21.9 %). Changes of lipid variables in placebo were not significant. Treatment effects were persistent, even slightly enhanced, during the trial. At study completion, policosanol had lowered (p < 0.00001) LDL-C (31.8 %) and TC (20.1 %), while markedly raised (p < 0.00001) HDL-C (24.6 %). Thirty patients (18 placebo, 12 policosanol) discontinued the study: 15 (11 placebo, 4 policosanol) due to AE and 12 (9 placebo, 3 policosanol) due to serious adverse events (SAE), most vascular. Policosanol was safe and well tolerated, not impairing significantly any safety indicator. Average body weight was slightly reduced over the study, indicating a general acceptable compliance with dietary recommendations, but policosanol did not show any drug effect on body weight. Overall, 28 placebo and 26 policosanol patients reported some mild or moderate AE during the study. It is concluded that policosanol was effective for lowering cholesterol in obese patients with type II hypercholesterolemia, being also safe and well tolerated. **** End Abstract **** Yes, the reduction is average body weight does mean that the obese study subjects were eating less during the 3 year study period as per the study design. Many thanks, much praise, and all the glory to GOD for compelling you to provide this citation to confirm what HE has led me to write despite your intention to discredit. Laus Deo ! > Once again we find confirmation of a poor grasp of current literature, a > non-scientific driven agenda which distorts the discussion, and a > continuing reason to safely ignore the source because the truth is not > in it. Actually, you are not safe opposing the truth, Who is LORD Jesus Christ. Simply see above. May GOD continue to keep your heart beating (unless you choose unwisely to curse HIM as did Sigmund Freud when he died in excruciating pain, unsettling anxiety, and teeth gnashing panic) dear neighbor whom I love unconditionally. Prayerfully in Christ's amazing love, Andrew <>< -- Andrew B. Chung Cardiologist, Atlanta, Georgia, USA http://HeartMDPhD.com/HolySpirit As for knowing who are the very elect, these you will know by the unconditional love they have for everyone including their enemies (Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17). http://HeartMDPhD.com/Love >> "In my clinical experience, policosanol will not work in folks who are >> overeating. [quoted text clipped - 12 lines] > >Both hypercholesterolemia (HC) and ob Shuttup, spammer. Follow this and see why this source is not to be relied upon for science and medical advice, mr. chung offered his opinion: >> "In my clinical experience, policosanol will not work in folks who are >> overeating. [quoted text clipped - 10 lines] > >Here's the abstract: Good to see you come down from the mountain and attempt to do some real science, but alas: "Average body weight was slightly reduced over the study, indicating a general acceptable compliance with dietary recommendations, but policosanol did not show any drug effect on body weight." and: "It is concluded that policosanol was effective for lowering cholesterol in obese patients with type II hypercholesterolemia, being also safe and well tolerated." Mr. chung spins and twirls: "Yes, the reduction is average body weight does mean that the obese study subjects were eating less during the 3 year study period as per the study design." No as the above conclusions clearly say, and the truth is not in you. Your grasp of the recent relevant literature is poor, you force unwarrented conclusions based on non-scientific agenda goals, your advice in this area can without hesitation be ignored, because the truth is not in it. Nymshifting neighbor CoonSkin shrieked: > Andrew, in the Holy Spirit, boldly wrote: > [quoted text clipped - 20 lines] > policosanol > did not show any drug effect on body weight." **emphasis** added. > and: > [quoted text clipped - 3 lines] > well > tolerated." Actually, based on the study design, these would be obese patients who have been compliant with instructions to lose weight. > Andrew, in the Holy Spirit, boldly writes: > [quoted text clipped - 9 lines] > advice in this area can without hesitation be ignored, because the truth > is not in it. See **emphasis** above. Where there is weight reduction, there has not been overeating. Overeating causes weight gain and not weight loss. Truth is simple. Bottomline: You remain consistently untruthful. May GOD continue to keep your heart beating (unless you choose unwisely to curse HIM) dear neighbor CoonSkin whom I love unconditionally. Prayerfully in Christ's amazing love, Andrew <>< -- Andrew B. Chung Cardiologist, Atlanta, Georgia, USA http://HeartMDPhD.com/HolySpirit As for knowing who are the very elect, these you will know by the unconditional love they have for everyone including their enemies (Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17). http://HeartMDPhD.com/Love >Nymshifting neighbor CoonSkin shrieked: Can you be any bigger of a hypocrite, Chunk? I think not. Mr. chung offeres an ever weakening opinion: "Actually, based on the study design, these would be obese patients who have been compliant with instructions to lose weight." Actually this is what happened: "Average body weight was slightly reduced over the study" "Slightly" is not significant when we arespeaking of "obese" folk, that term taken usually to mean a bmi of > 30 where 25 is the upper number for "normal". Your original claim was "normal" people only saw results with the substance, "slight" weight loss in "obese" subjects don't cut it, smile. I will consult the original paper in full if you think the numbers it will no doubt detail will help you, smile. Also happy to list the many studies done using this substance wherein the bmi was often noted, if you think that also will help you, smile. Only more confirmation for seeing poor grasp of current literature in this area, willingness to distort information in pursuit of non-scientific goals, added reason to ignore the source because the truth is not in it. Nymshifting neighbor (aka CoonSkin) wrote: > Andrew, in the Holy Spirit, boldly wrote: > [quoted text clipped - 4 lines] > > "Average body weight was slightly reduced over the study" Correct. This does indicate an effort to eat less. It remains my clinical experience that policosanol does not work in folks that are not making an effort to eat less. Like it or not, your cited reference supports my clinical experience to your dismay. All the praise and glory belongs to GOD, Whom I love with all my heart, soul, mind, and strength. Your embarrassing yourself is an adverse reaction to the awesome power of intercessory prayers by the brethren of LORD Jesus Christ made to our heavenly Father lifting up those like you who have been convicted by the Holy Spirit: http://HeartMDPhD.com/Convicts May GOD continue to keep your heart beating (unless you unwisely choose to curse HIM) dear neighbor CoonSkin whom I love unconditionally. Prayerfully in Christ's amazing love, Andrew <>< -- Andrew B. Chung Cardiologist, Atlanta, Georgia, USA http://HeartMDPhD.com/HolySpirit As for knowing who are the very elect, these you will know by the unconditional love they have for everyone including their enemies (Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17). http://HeartMDPhD.com/Love >Nymshifting neighbor (aka CoonSkin) wrote: Hypocrite. >> Andrew, in the Holy Spirit, boldly wrote: >> [quoted text clipped - 22 lines] > >http://redacted-kooklink Still spamming your kooklink, Chunk? > "Actually, based on the study design, these would be obese patients who > have been compliant with instructions to lose weight." > Actually this is what happened: > > "Average body weight was slightly reduced over the study" "Correct. This does indicate an effort to eat less. It remains my clinical experience that policosanol does not work in folks that are not making an effort to eat less. Like it or not, your cited reference supports my clinical experience to your dismay." We start with obese people, bmi > 30 and a slight weight loss occurs, meaning they remained obese at study end. Your claim was that only normal weight people found the substance effective, in other words your claims not clinically seen. In a desperate move you try now to say if they try to lose weight it works, truth matters. I'm happy for the truth to be seen repeatably that there can in the end remain no possible confusion that: Grasp of current literature in this area is poor, that willfull distortions are made in pursuit of non-scientific agendas, that safely ignoring the source is called for because the truth is not in it. Nymshifting neighbor (aka CoonSkin) wrote: > > "Actually, based on the study design, these would be obese patients > who [quoted text clipped - 15 lines] > meaning they remained obese at study end. Your claim was that only > normal weight people found the substance effective No. "In my clinical experience, policosanol will not work in folks who are overeating." Google archive citation: http://groups.google.com/group/sci.med.cardiology/msg/11e730c8f083c93d? The Google archives are not a friend to the untruthful. Bottomline: You remain consistently untruthful. If your intent is to deceive, GOD will judge you to be a liar. May GOD continue to keep your heart beating (unless you unwisely choose to curse HIM) dear neighbor CoonSkin whom I love unconditionally. Prayerfully in Christ's amazing love, Andrew <>< -- Andrew B. Chung Cardiologist, Atlanta, Georgia, USA http://HeartMDPhD.com/HolySpirit As for knowing who are the very elect, these you will know by the unconditional love they have for everyone including their enemies (Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17). http://HeartMDPhD.com/Love >Nymshifting neighbor (aka CoonSkin) wrote: Hypocrite. > Andrew, in the Holy Spirit, boldly wrote: > > >Nymshifting neighbor (aka CoonSkin) wrote: > > Hypocrite. Hiding behind multiple pseudonyms is not my style. May GOD continue to keep your heart beating (unless you unwisely choose to curse HIM) dear neighbor Art whom I love unconditionally. Prayerfully in Christ's amazing love, Andrew <>< -- Andrew B. Chung Cardiologist, Atlanta, Georgia, USA http://HeartMDPhD.com/HolySpirit As for knowing who are the very elect, these you will know by the unconditional love they have for everyone including their enemies (Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17). http://HeartMDPhD.com/Love >>Nymshifting neighbor (aka CoonSkin) wrote: > >Hypocrite. You expected something else from Wang Chung? ESL! SignatureBookman -The Official Overseer of Kooks and Trolls in AFA-B Kazoo Konspirator #668 (The Neighbor of the Beast) Clue-Bat Wrangler Keeper of the Nickname Lists Despotic Kookologist of the New World Order Hammer of Thor award, October 2005 COOSN-266-06-89425 "I'd love to kill you in a ring" - Bartmo gets all touchy-feely "****SPV....... So yes I am an idiot." "ASK THE NWS, YOUR TAX DOLLAR GOES TO THEM NOT TO DR.TURI." - Mr. Turi explains how to accurately predict hurricanes Bookman is yet another Usenet fignuten, meaning naysayer and/or rusemaster of their incest cloned Third Reich. In other words, you're communicating with an intellectual if not a biological clone of Hitler. - Brad Guth tries to wax "scientific", but invokes Godwin, instead. WWFSMD? > We start with obese people, bmi > 30 and a slight weight loss occurs, > meaning they remained obese at study end. Your claim was that only > normal weight people found the substance effective "No. "In my clinical experience, policosanol will not work in folks who are overeating."" No, not clinically seen, but this rhetorical tap dancing behavior frequently clinically seen in other disorders. People who are obese, the tern used in the study, are overeating and the substance was reported to work, your anecdotal observations not clinically supported in science. Leading as before to: A poor grasp of the current literature on the subject, willfull distortions in pursuit of a non-scientific agenda, all the more reason to ignore the source because the truth is not in it. http://groups.google.com/group/sci.med.cardiology/msg/383fcc9d429f8b91? > > We start with obese people, bmi > 30 and a slight weight loss occurs, > > meaning they remained obese at study end. Your claim was that only [quoted text clipped - 15 lines] > distortions in pursuit of a non-scientific agenda, all the more reason > to ignore the source because the truth is not in it. Mr. chung offered this: Unable to answer, mr. chung can only offer:" http://groups.google.com/group/sci.med.cardiology/msg/383fcc9d429f8b91?" When he is defeated he posts links to other or previous versions of a thread. When he has nothing more original to add and realizes the corner into which he has put himself he stutters with links. Saving paper face at any cost is extremely important among those things that motivate him. When losing on the science he stutters, confirming: Poor grasp of recent literature in the area, willfull distortions in pursuit of a non-scientific goal, rhetoric in place of reason and logic, final confirmation to be at ease in ignoring the source because the truth is not in it. |
Reply to this Message |
 Sign In
 Join
 My Latest Posts My Monitored Threads My Blog My Photo Gallery My Profile My Homepage Start New Thread Enable EMail Alerts Rate this Thread
|
©2009 Advenet LLC Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.