My wife has labile blood pressure that spikes really high. Her
physican prescribed Toprol XL which didn't seem to help much until she
stopped using Vitamin E supplements when the blood pressure suddenly
stabilized. We found one refence online (University of Maryland
website) theorizing that Vitamin E inhibits the effect of beta blockers
like Toprol, but have been unable to verify that information.
Last night, her blood pressure spiked again, after she had been eating
a lot of blueberries for a couple of days. Is it possible that the
antioxidant effect of blueberries is acting the same as the vitamin E
in reducing the effect of Toprol? Are there any studies that might
shed more light on this effect including other foods to be avoided?
Thank you very much.
> My wife has labile blood pressure that spikes really high. Her
> physican prescribed Toprol XL which didn't seem to help much until she
[quoted text clipped - 8 lines]
> in reducing the effect of Toprol? Are there any studies that might
> shed more light on this effect including other foods to be avoided?
Toprol XL is a substrate for CYP450:D6 which is subject to a lot of
interindividual variability. It is certainly possibly that your wife's
CYP450:D6 system is activated ny antioxidants such as vitamin E and
similar compounds in the blueberries.
> Thank you very much.
You are welcome.
All thanks and praises belong to the LORD, Whom I love with all my
being.
Prayerfully in Christ's amazing love,
Andrew B. Chung
Cardiologist, Atlanta, Georgia, USA
http://tinyurl.com/frep8