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Medical Forum / General / Cardiology / May 2006

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What's a person to do???

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jd - 30 May 2006 04:01 GMT
Hubby had a heart attack 2 years ago.  59 yo /  low normal blood pressure  /
low normal cholesterol  /  very lean  /  very active (tradesman)  /  picture
of health most would say  /  good diet  / no smoke or booze.  Right coronary
artery blocked and had a stent implanted.  He's VERY lucky to be here.  1
1/2 years after his HA he had another event.  Stent implanted LAD.  The
angiogram shows the LAD to be clear when he had the stent implanted in his
RCA a year and a half before.  After a year and a half there was no room for
improvement in lifestyle.  He took the usual cocktail of meds after the HA
and was weaned off due to his doing so well.  Now, after the LAD stent he is
on Plavix, aspirin,  Niaspan, Lipitor, fish oils.  He is seeing a lipid
specialist/cardiologist.  His numbers are good, but they were before all
this too.
Now he just stopped his Lipitor due to severe muscle cramps and the doc
wrote him a script for Zetia.  He'll start that tomorrow.  I don't mind
telling you that I am not confident about the Zetia.  I hate that he is on
the cholesterol med, but afraid too.
I have been reading this NG for a long time and have studied nutrition /
various med problems / and meds for the past 30 years.
I have a somewhat wide macrobiotic practice myself.   The last time I was
tested, my cholesterol was UP  /  trigs WAY UP  /  HDL down.
So the conclusion I think I am coming to is that I don't know sh** from
shinola and neither does anybody else.  I apologize for the long rant, but I
felt the need tonight for some odd reason.  Thanks for listening.
jay1000 - 30 May 2006 04:49 GMT
> Hubby had a heart attack 2 years ago.  59 yo /  low normal blood pressure
> / low normal cholesterol  /  very lean  /  very active (tradesman)  /
[quoted text clipped - 19 lines]
> shinola and neither does anybody else.  I apologize for the long rant, but
> I felt the need tonight for some odd reason.  Thanks for listening.

I had muscle cramps and muscle twitching on Lipitor and then on Zocor.  I'm
now on Pravachol and no muscle problems.  According to my doc, it is
metabolized differently than the other statins.   It's not as effective as
Lipitor or Zocor in reducing cholesterol but it is good enough.  Total 150 &
LDL 80 on 20 mg dose.  I actually split the pill and take 10 mg in am and 10
mg in pm.  That keeps the blood serum concentration from peaking as much as
with a single dose (my theory).
jd - 30 May 2006 04:53 GMT
sounds like a good and reasonable theory  LOL.  Hubby had problems with
Zocor and then another one  /  I think it was atorvastatin?  Can't remember
right now.  So the Lipitor was his 3rd one.  All we can do is hope that the
Zetia does it's job.  I mean what's the alternative?  lol
William Wagner - 30 May 2006 10:51 GMT
> sounds like a good and reasonable theory  LOL.  Hubby had problems with
> Zocor and then another one  /  I think it was atorvastatin?  Can't remember
> right now.  So the Lipitor was his 3rd one.  All we can do is hope that the
> Zetia does it's job.  I mean what's the alternative?  lol

Here one.

Best

Bill

............................

VITAL SIGNS: NUTRITION; Red Grapefruit Earns a Star on Chole...
http://query.nytimes.com/gst/fullpage.html?sec=health&res=9F03E...
1 of 2 5/20/06 6:28 AM
VITAL SIGNS: NUTRITION; Red
Grapefruit Earns a Star on Cholesterol

By NICHOLAS BAKALAR
Published: February 21, 2006

VITAL SIGNS: NUTRITION; Red Grapefruit Earns a Star on Chole...
http://query.nytimes.com/gst/fullpage.html?sec=health&res=9F03E...
2 of 2 5/20/06 6:28 AM
More Articles in Health >

Grapefruit, especially the deep red star ruby variety, can help reduce
cholesterol in some patients who do not respond to statin drugs,
researchers in Israel are reporting.
The researchers tested 57 patients ages 39 to 72 who had undergone
coronary bypass surgery and had found that Zocor, or simvastatin, was
ineffective. They divided them randomly into three groups.
Each group consumed the same diet, except that one ate one red
grapefruit daily, the second ate one white grapefruit, and the third ate
no grapefruit at all. None took lipid-lowering drugs during the test.
After one month, there were no differences in the heart rate, blood
pressure or weight of the three groups. Antioxidant activity in both
white and red groups was increased compared with the group that ate
no grapefruit.
But the group that ate red grapefruit every day also had significantly
decreased blood levels of triglycerides.
The findings will be published in the March 22 issue of The Journal of
Agriculture and Food Chemistry.
Although it is well known that grapefruit and other citrus fruits contain
antioxidants that help control lipid levels, the researchers are unsure
exactly what components of red grapefruit make it so much more
effective than other varieties.
In any case, Shela Gorinstein of the Hebrew University of Jerusalem
School of Pharmacy, the study's lead author, said that eating red
grapefruit would ''most probably'' help anyone with high cholesterol,
not just heart patients.
The star ruby grapefruit has a yellow peel with a red blush and an
intensely red pulp. It is very sweet, and has few or no seeds.
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Joe Doe - 30 May 2006 20:16 GMT
> Now he just stopped his Lipitor due to severe muscle cramps and the doc
> wrote him a script for Zetia.  He'll start that tomorrow.  I don't mind
> telling you that I am not confident about the Zetia.  I hate that he is on
> the cholesterol med, but afraid too.

Zetia mechanism of action is different from the statins.  It works by
interfering with cholesterol absorption in the digestive tract while the
statins interfere with cholesterol synthesis.  Fiber in oatmeal etc.
works in an analogous way to Zetia.   While you may not like the idea of
drugs it is worth at least trying it to see if he can tolerate it.  

Best wishes.

Roland
 
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