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Medical Forum / General / Cardiology / December 2005

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Triglyceride/ HDL ratio

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tedw2@earthlink.net - 23 Dec 2005 05:34 GMT
Ive had 2 doctors look at my triglycerid level and HDL ratio and have
them tell me its fine. However, I was reviewing my blood tests tonight
and I noticed something they didnt see or more likely their education
is faulty.

My most recent HDL level was 51 which is above the reference range of
40.

My triglicerides level was 105 which is considerably less than the 150
reference range.

So they concluded they were ok.

However, tonight I was reading Dr. Atkins Age-defying diet ( a good
book in my opinion) and I read the following. in the section HIGH
TG/Low hdl: a deadly combination.

He says " Ideally  you want a ratio approaching 1:1  with your
triglycerides lower than your HDL. If your ratio is 2:1 with your
triglycerides higher than your HDL, your on the borderling of normal.
Anything higher than 2:1 begins to be serious.....your asking for
trouble"

Since I am already on a low carbohydrate diet and get plenty of
exercise (5-10 miles biking 5 days a week). I think Im going to try and
raise my HDL with non-prescription niacin. Anybody have any experience
with this?
Robert - 23 Dec 2005 07:58 GMT
> Ive had 2 doctors look at my triglycerid level and HDL ratio and have
> them tell me its fine. However, I was reviewing my blood tests tonight
> and I noticed something they didnt see or more likely their education
> is faulty.

Education faulty?

> My most recent HDL level was 51 which is above the reference range of
> 40.
[quoted text clipped - 3 lines]
>
> So they concluded they were ok.

Looks ok to me although HDL is more ideal over 60. The ratio is
2.05888235294

You are over the normal ratio of 2 by 0.0588235235294

Contrast this with a 37 year old female who presented with chest pain to the
hospital with the labs below.

TC 410
HDL 38
LDL141
TG 1501

TG/HDL ratio of 39.5

If your ratio is bad then this lady is in deep sh.t.

Lets not over react to numbers. Ratios are serrogates to something not being
tested. The ratio in this case is a serrogate for LDL particle size. The
higher the ratio the smaller the LDL particle and the more atherogenic.
It is always better to measure something which is what the VAP test does. It
reports the particle size and not simply a quantitative number but
qualitative also.

> However, tonight I was reading Dr. Atkins Age-defying diet ( a good
> book in my opinion) and I read the following. in the section HIGH
[quoted text clipped - 5 lines]
> Anything higher than 2:1 begins to be serious.....your asking for
> trouble"

There is a valid debate on whether HDL raising is more appropriate for
ladies vs LDL lowering for men.
My guess is that female hormones is somewhat protective under conditons of
adequate HDL levels. When HDL is low that protection is lost and when
menapause comes along then that places them in similar situations as men
with LDL being significant and or HDL levels being equally important.
I have trouble when somebody reduces everything into one single number or
ratio. It should be the opposite. You are looking at risk assement. The more
numbers the better an assessment can be made.

> Since I am already on a low carbohydrate diet and get plenty of
> exercise (5-10 miles biking 5 days a week). I think Im going to try and
> raise my HDL with non-prescription niacin. Anybody have any experience
> with this?

I had to drop it because of headaches. There are many benefits of exercise
beyond coronary risk and the same goes for eating well.
Andrew B. Chung, MD/PhD - 23 Dec 2005 11:07 GMT
<snip>
> > Since I am already on a low carbohydrate diet and get plenty of
> > exercise (5-10 miles biking 5 days a week). I think Im going to try and
[quoted text clipped - 3 lines]
> I had to drop it because of headaches. There are many benefits of exercise
> beyond coronary risk and the same goes for eating well.

Wiser to eat less down to the optimal amount if there is significant
visceral adiposity especially if low HDL is a concern (ie metabolic
syndrome).

Would be more than happy to "glow" and chat about this and other things
like cardiology, diabetes and nutrition that interest those following
this thread here during the next on-line chat (12/29/05) from 6 to 7 pm
EST:

http://tinyurl.com/cpayh

For those who are put off by the signature, my advance apologies for
how the LORD has reshaped me:

http://tinyurl.com/bgfqt

Many Christmas blessings,

Andrew
http://tinyurl.com/b6xwk
tedw2@earthlink.net - 23 Dec 2005 19:32 GMT
Good idea but Im down to 2 meals a day now.and the meals generally
arent all that big.
Andrew B. Chung, MD/PhD - 23 Dec 2005 21:02 GMT
> Good idea but Im down to 2 meals a day now.and the meals generally
> arent all that big.

Even one meal can be excessive in amount of food.  The ability to
estimate the amount of food deteriorates with healthier appetites.

Would be more than happy to "glow" and chat about this and other things
like cardiology, diabetes and nutrition that interest those following
this thread here during the next on-line chat (12/29/05):

http://tinyurl.com/cpayh

For those who are put off by the signature, my advance apologies for
how the LORD has reshaped me:

http://tinyurl.com/bgfqt

In Christ's love always,

Andrew
http://tinyurl.com/b6xwk
Jim Chinnis - 23 Dec 2005 23:55 GMT
"tedw2@earthlink.net" <tedw2@earthlink.net> wrote in part:

>Ive had 2 doctors look at my triglycerid level and HDL ratio and have
>them tell me its fine. However, I was reviewing my blood tests tonight
[quoted text clipped - 23 lines]
>raise my HDL with non-prescription niacin. Anybody have any experience
>with this?

Eat more fatty fish or take fish oil supplements. That will drop the TG a
bit more. A glass of wine a day will boost HDL, if you are currently a
non-drinker.
--
Jim Chinnis   Warrenton, Virginia, USA
tedw2@earthlink.net - 24 Dec 2005 04:16 GMT
> "tedw2@earthlink.net" <tedw2@earthlink.net> wrote in part:
>
[quoted text clipped - 31 lines]
> --
> Jim Chinnis   Warrenton, Virginia, USA

Already take 18 fish oil capsules daily. Wine not an option:  Stage 3
liver disease due to hepatitis.
Jim Chinnis - 25 Dec 2005 04:10 GMT
"tedw2@earthlink.net" <tedw2@earthlink.net> wrote in part:

>> "tedw2@earthlink.net" <tedw2@earthlink.net> wrote in part:
>>
[quoted text clipped - 34 lines]
>Already take 18 fish oil capsules daily. Wine not an option:  Stage 3
>liver disease due to hepatitis.

Then niacin may be not an option, either. (Ask your doc.)
--
Jim Chinnis   Warrenton, Virginia, USA
tedw2@earthlink.net - 25 Dec 2005 05:17 GMT
Im going to try a combination of pantothenic acid and pantethine.  No
adverse effects noted to the liver.

Actually, Im finding that by doing my own research on internet I soon
know more than  the Doctors about a certain condtion. The last time I
went to Kaiser I was educating the Nurse in charge of my case about the
new treatments for hep C.

There is so much information out there they cannot possibly keep up
with it. And not having liver disease or hep C they are not as
motivated as I am.
Susan - 25 Dec 2005 18:51 GMT
> Im going to try a combination of pantothenic acid and pantethine.  No
> adverse effects noted to the liver.
[quoted text clipped - 7 lines]
> with it. And not having liver disease or hep C they are not as
> motivated as I am.

You may want to, if you haven't already, do some Medline research on
alpha lipoic acid (also referred to as thioctic acid), silymarin, and
n-acetylcysteine (sp?) for reversing liver damage.  Bring what you find
to discuss with your doc.

Susan
tedw2@earthlink.net - 25 Dec 2005 19:20 GMT
They already told me not to take milkthistle during the clinical trial.
Alpha lipoic acid is one of the supplements I take.
 
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