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Medical Forum / General / Cardiology / March 2005

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Waist Circumference, BMI, and Cardiac Risk

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Don Kirkman - 24 Feb 2005 18:47 GMT
I had seen news reports similar to this before, but a recent study
apparently concludes that waist circumference is a better indicator of
cardiac risk than body mass index.  According to the report on Medscape,
this is true for lipid profiles, blood pressure, and glucose levels; the
correlation holds across three ethnic groups.
http://www.medscape.com/viewarticle/499868
[Am J Clin Nutr 2005;81:409-415]
Signature

Don
"I do not feel obliged to believe that the same God who has endowed
us with senses, reason, and intellect has intended us to forgo their
use.                                --Galileo Galilei

elgoog - 24 Feb 2005 19:30 GMT
Same article available without the registration required at medscape.
http://news.yahoo.com/news?tmpl=story&u=/nm/20050221/hl_nm/waist_heart_dc_1

Here's another article from a different study, same conclusions.
http://my.webmd.com/content/article/50/40452?src=Inktomi&condition=Healthy%20Seniors

So my read on this is that men should have waists of no more than 35
inches (89 cm) and women waist sizes of no more than 33 inches (83 cm).

Any ideas how this could hold universally true without any
consideration of height, weight and maybe other factors like nutrition,
sleep and exercise?
Andrew B. Chung, MD/PhD - 24 Feb 2005 19:51 GMT
> Same article available without the registration required at medscape.
> http://news.yahoo.com/news?tmpl=story&u=/nm/20050221/hl_nm/waist_heart_dc_1
[quoted text clipped - 8 lines]
> consideration of height, weight and maybe other factors like nutrition,
> sleep and exercise?

By God's design.


At His service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?L26062048
(2) http://makeashorterlink.com/?O2F325D1A
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
elgoog - 24 Feb 2005 19:35 GMT
My favorite Galileo quote,
"'You cannot teach a man anything; you can only help him to find it
within himself."
    - Galileo Galilei
Andrew B. Chung, MD/PhD - 24 Feb 2005 19:51 GMT
> My favorite Galileo quote,
> "'You cannot teach a man anything; you can only help him to find it
> within himself."
>      - Galileo Galilei

“With man this is impossible, but with God all things are possible.”
      - Lord Jesus Christ

At His service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?L26062048
(2) http://makeashorterlink.com/?O2F325D1A
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
William Wagner - 24 Feb 2005 19:52 GMT
> My favorite Galileo quote,
> "'You cannot teach a man anything; you can only help him to find it
> within himself."
>      - Galileo Galilei

Educare to bring out.  A lot different then placing in, I guess it is
the old blank slate argument vis intrinsic intelligence.
I?m with Galileo  and Su Tunpo  on this one.

Oh  Your quote warms my heart so we be on topic.  ;))

Bill

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Zone 5 S Jersey USA Shade
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Andrew B. Chung, MD/PhD - 24 Feb 2005 19:51 GMT
> I had seen news reports similar to this before, but a recent study
> apparently concludes that waist circumference is a better indicator of
[quoted text clipped - 5 lines]
> --
> Don

As has been discussed before here in SMC, for most folks there is a
strong correlation between weight/BMI and waist circumference.  This is
why when folks lose weight, they generally find their clothes fitting
more loosely around the waist and when they gain, the clothes are
tighter around the waist.

> "I do not feel obliged to believe that the same God who has endowed
> us with senses, reason, and intellect has intended us to forgo their
> use.                                --Galileo Galilei

In truth,  nowhere in the holy Bible are there instructions to not use
the abilities He has given us.  

At His service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?L26062048
(2) http://makeashorterlink.com/?O2F325D1A
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
Don Kirkman - 25 Feb 2005 23:41 GMT
It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
article <1109274360.8e31efaa3a53bbd4dbfb846d3fd314ed@teranews>:

>> I had seen news reports similar to this before, but a recent study
>> apparently concludes that waist circumference is a better indicator of
[quoted text clipped - 3 lines]
>> http://www.medscape.com/viewarticle/499868
>> [Am J Clin Nutr 2005;81:409-415]

>As has been discussed before here in SMC, for most folks there is a
>strong correlation between weight/BMI and waist circumference.  This is
>why when folks lose weight, they generally find their clothes fitting
>more loosely around the waist and when they gain, the clothes are
>tighter around the waist.

Yes, but apparently a stronger correlation between WC and cardiac risk
than between BMI and cardiac risk, which is what the study was looking
at.

>In truth,  nowhere in the holy Bible are there instructions to not use
>the abilities He has given us.  

And yet so many religious (and non-religious) people live as though
there were.
Signature

Don
"I do not feel obliged to believe that the same God who has endowed
us with senses, reason, and intellect has intended us to forgo their
use.                                --Galileo Galilei

Andrew B. Chung, MD/PhD - 26 Feb 2005 13:25 GMT
> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
> article <1109274360.8e31efaa3a53bbd4dbfb846d3fd314ed@teranews>:
[quoted text clipped - 16 lines]
> than between BMI and cardiac risk, which is what the study was looking
> at.

Perhaps across different individuals per the study but should be the
same degree of correlation in any *one* individual.

> >In truth,  nowhere in the holy Bible are there instructions to not use
> >the abilities He has given us.
>
> And yet so many religious (and non-religious) people live as though
> there were.

That would be their choice.


At His service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?L26062048
(2) http://makeashorterlink.com/?O2F325D1A
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
Don Kirkman - 26 Feb 2005 20:26 GMT
It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
article <1109424268.a7b5858b7394edb02f5244d2742e85f9@teranews>:

>> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
>> article <1109274360.8e31efaa3a53bbd4dbfb846d3fd314ed@teranews>:


>> >> I had seen news reports similar to this before, but a recent study
>> >> apparently concludes that waist circumference is a better indicator of
[quoted text clipped - 3 lines]
>> >> http://www.medscape.com/viewarticle/499868
>> >> [Am J Clin Nutr 2005;81:409-415]

>> >As has been discussed before here in SMC, for most folks there is a
>> >strong correlation between weight/BMI and waist circumference.  This is
>> >why when folks lose weight, they generally find their clothes fitting
>> >more loosely around the waist and when they gain, the clothes are
>> >tighter around the waist.

>> Yes, but apparently a stronger correlation between WC and cardiac risk
>> than between BMI and cardiac risk, which is what the study was looking
>> at.

>Perhaps across different individuals per the study but should be the
>same degree of correlation in any *one* individual.

Can you explain that, please?  You can't usually do statistics with one
individual.  Are you talking about correlating BMI to WC, which was not
the issue, or how both BMI and WC separately correlate to cardiac risk,
which was the issue?
Signature

Don
"I do not feel obliged to believe that the same God who has endowed
us with senses, reason, and intellect has intended us to forgo their
use.                                --Galileo Galilei

Andrew B. Chung, MD/PhD - 27 Feb 2005 01:38 GMT
> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
> article <1109424268.a7b5858b7394edb02f5244d2742e85f9@teranews>:
[quoted text clipped - 27 lines]
> the issue, or how both BMI and WC separately correlate to cardiac risk,
> which was the issue?

In truth, you can perform a statistical analysis of repeated measures
from a single individual to determine correlation with an independent
variable that is of interest.

At His service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?L26062048
(2) http://makeashorterlink.com/?O2F325D1A
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
Don Kirkman - 27 Feb 2005 19:46 GMT
It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
article <1109468267.230e6510c922cf559d3d633d91a66db4@teranews>:


>> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
>> article <1109424268.a7b5858b7394edb02f5244d2742e85f9@teranews>:


>> >> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
>> >> article <1109274360.8e31efaa3a53bbd4dbfb846d3fd314ed@teranews>:

>> >> >> I had seen news reports similar to this before, but a recent study
>> >> >> apparently concludes that waist circumference is a better indicator of
[quoted text clipped - 3 lines]
>> >> >> http://www.medscape.com/viewarticle/499868
>> >> >> [Am J Clin Nutr 2005;81:409-415]

>> >> >As has been discussed before here in SMC, for most folks there is a
>> >> >strong correlation between weight/BMI and waist circumference.  This is
>> >> >why when folks lose weight, they generally find their clothes fitting
>> >> >more loosely around the waist and when they gain, the clothes are
>> >> >tighter around the waist.

>> >> Yes, but apparently a stronger correlation between WC and cardiac risk
>> >> than between BMI and cardiac risk, which is what the study was looking
>> >> at.

>> >Perhaps across different individuals per the study but should be the
>> >same degree of correlation in any *one* individual.

>> Can you explain that, please?  You can't usually do statistics with one
>> individual.  Are you talking about correlating BMI to WC, which was not
>> the issue, or how both BMI and WC separately correlate to cardiac risk,
>> which was the issue?

>In truth, you can perform a statistical analysis of repeated measures
>from a single individual to determine correlation with an independent
>variable that is of interest.

As I asked before, can you **explain** that, please, instead of just
dropping off single-sentence pronouncements?  Exactly how does one go
about doing that in a way that shows how waist circumference and body
mass index each correlate individually to cardiac risk?  And how do you
correlate any results to population studies which are the norm in
clinical trials?
Signature

Don
"I do not feel obliged to believe that the same God who has endowed
us with senses, reason, and intellect has intended us to forgo their
use.                                --Galileo Galilei

Andrew B. Chung, MD/PhD - 27 Feb 2005 22:52 GMT
> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
> article <1109468267.230e6510c922cf559d3d633d91a66db4@teranews>:
[quoted text clipped - 37 lines]
> As I asked before, can you **explain** that, please, instead of just
> dropping off single-sentence pronouncements?

I can as needed.

> Exactly how does one go
> about doing that in a way that shows how waist circumference and body
> mass index each correlate individually to cardiac risk?

One can measure a surrogate marker such as hsCRP (or total cholesterol
to HDL ratio). This would be a measure of cardiac risk (dependent
variable) as the independent variable (either BMI or WC) varies.

> And how do you
> correlate any results to population studies which are the norm in
> clinical trials?

By predicting that an increase in the surrogate marker (s) with
increasing BMI/WC within one individual represents an increase in
cardiovascular risk just as seen across individuals.


At His service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?L26062048
(2) http://makeashorterlink.com/?O2F325D1A
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
Don Kirkman - 01 Mar 2005 01:18 GMT
It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
article <1109544764.64ec147b3f8b717bcec5620747d55966@teranews>:

>> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
>> article <1109468267.230e6510c922cf559d3d633d91a66db4@teranews>:

>> >> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
>> >> article <1109424268.a7b5858b7394edb02f5244d2742e85f9@teranews>:


>> >> >> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
>> >> >> article <1109274360.8e31efaa3a53bbd4dbfb846d3fd314ed@teranews>:

>> >> >> >> I had seen news reports similar to this before, but a recent study
>> >> >> >> apparently concludes that waist circumference is a better indicator of
[quoted text clipped - 3 lines]
>> >> >> >> http://www.medscape.com/viewarticle/499868
>> >> >> >> [Am J Clin Nutr 2005;81:409-415]

>> >> >> >As has been discussed before here in SMC, for most folks there is a
>> >> >> >strong correlation between weight/BMI and waist circumference.  This is
>> >> >> >why when folks lose weight, they generally find their clothes fitting
>> >> >> >more loosely around the waist and when they gain, the clothes are
>> >> >> >tighter around the waist.

>> >> >> Yes, but apparently a stronger correlation between WC and cardiac risk
>> >> >> than between BMI and cardiac risk, which is what the study was looking
>> >> >> at.

>> >> >Perhaps across different individuals per the study but should be the
>> >> >same degree of correlation in any *one* individual.

>> >> Can you explain that, please?  You can't usually do statistics with one
>> >> individual.  Are you talking about correlating BMI to WC, which was not
>> >> the issue, or how both BMI and WC separately correlate to cardiac risk,
>> >> which was the issue?

>> >In truth, you can perform a statistical analysis of repeated measures
>> >from a single individual to determine correlation with an independent
>> >variable that is of interest.

>> Exactly how does one go
>> about doing that in a way that shows how waist circumference and body
>> mass index each correlate individually to cardiac risk?

>One can measure a surrogate marker such as hsCRP (or total cholesterol
>to HDL ratio). This would be a measure of cardiac risk (dependent
>variable) as the independent variable (either BMI or WC) varies.

>> And how do you
>> correlate any results to population studies which are the norm in
>> clinical trials?

>By predicting that an increase in the surrogate marker (s) with
>increasing BMI/WC within one individual represents an increase in
>cardiovascular risk just as seen across individuals.

I appreciate you spelling it out, though I must confess I don't see any
criteria or protocol to measure whether BMI or WC more closely tracks
cardiac risk, which was the point of the study.  I assume by tracking
both independent variables against cardiac risk this would be obtained.
My remaining question, I suppose, is why bother to approach the issue
this way rather than directly from the population studies, which ISTM
would provide a curve from which individual probabilities could be
projected.  What can you do with studies from one individual that apply
to a patient population?
Signature

Don
"I do not feel obliged to believe that the same God who has endowed
us with senses, reason, and intellect has intended us to forgo their
use.                                --Galileo Galilei

Andrew B. Chung, MD/PhD - 01 Mar 2005 03:52 GMT
> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
> article <1109544764.64ec147b3f8b717bcec5620747d55966@teranews>:
[quoted text clipped - 63 lines]
> projected.  What can you do with studies from one individual that apply
> to a patient population?

Answer questions regarding the relationship(s) between variables within
single individuals.


At His service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?L26062048
(2) http://makeashorterlink.com/?O2F325D1A
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
Don Kirkman - 02 Mar 2005 00:05 GMT
It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
article <1109649297.aec20786c7821d2789e589333ce5f7a2@teranews>:

[. . .]

>> I appreciate you spelling it out, though I must confess I don't see any
>> criteria or protocol to measure whether BMI or WC more closely tracks
[quoted text clipped - 5 lines]
>> projected.  What can you do with studies from one individual that apply
>> to a patient population?

>Answer questions regarding the relationship(s) between variables within
>single individuals.

For developing a plan to lower risk and hopefully prevent an MI, or for
tracking results of treatment of a patent cardiac problem?

Thanks for your answers in this thread.
Signature

Don
"I do not feel obliged to believe that the same God who has endowed
us with senses, reason, and intellect has intended us to forgo their
use.                                --Galileo Galilei

Andrew B. Chung, MD/PhD - 02 Mar 2005 10:55 GMT
> It seems to me I heard somewhere that Andrew B. Chung, MD/PhD wrote in
> article <1109649297.aec20786c7821d2789e589333ce5f7a2@teranews>:
[quoted text clipped - 16 lines]
> For developing a plan to lower risk and hopefully prevent an MI, or for
> tracking results of treatment of a patent cardiac problem?

Either question or others such as whether what is learned about the
relationship(s) of these variables in the population is actually
applicable to the individual.

> Thanks for your answers in this thread.

You are welcome :-)


At His service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?L26062048
(2) http://makeashorterlink.com/?O2F325D1A
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
 
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