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Medical Forum / General / Cardiology / January 2005High Triglycerides but low Chlorest?
I just had a annual "lab work" blood test done and observed that my triglycerides are slightly out of range, higher than normal (300 or so) while my Chloresterol is 180. The lab results do not delineate "good" or "bad" cholesterol. I am healthy in all aspects and work out and walk routinely. No fast foods. Is this something to worry about? Is a stroke/heart attack/end of the world pending? How can one reduce triglycerides? It could signal the beginning of the metabolic syndrom. It is often related to overeating and overweight. Triglycerides are made by the liver and are a fat product that becomes stored as body fat. Did your doc do a blood glucose set of tests also? High glucose often goes with higher trigs as symptoms. Diet and weight control and exercise is the best way short of drugs to control them. >I just had a annual "lab work" blood test done and observed that my >triglycerides are slightly out of range, higher than normal (300 or so) [quoted text clipped - 8 lines] > >How can one reduce triglycerides? > "Steve" <billpritjr@spamhole.com> wrote in message > How can one reduce triglycerides? If it's VLDL triglycerides, reduce your *simple* sugar intake (all the sweet stuff). Complex carbs, and to some degree, refined carbs are ok. does beer/wine intake raise VLDL ? "Pouta" <aquarius_122@hotmail.com> wrote in message > does beer/wine intake raise VLDL ? Alcohol is an exception to the 'simple carb' rule, so beer (unless it has extra sugar added) and wine won't raise VLDL. > "Pouta" <aquarius_122@hotmail.com> wrote in message > > does beer/wine intake raise VLDL ? > :: > Alcohol is an exception to the 'simple carb' rule, > so beer (unless it has extra sugar added) and wine > won't raise VLDL. All alcohol will raise triglycerides and people should refrain from drinking alcohol before doing lipid panels. >"Robert" <RobertJ@hotmail.com> wrote > [quoted text clipped - 7 lines] > All alcohol will raise triglycerides and people should refrain from drinking > alcohol before doing lipid panels. There are 'good' and 'bad' triglycerides. Pouta was inquiring about VLDL, which alcohol WON'T raise, but in fact lowers, hence the favorable effect on CVD and blood glucose (in addition to polyphenols present in some alcoholic beverages). > >"Robert" <RobertJ@hotmail.com> wrote > > [quoted text clipped - 13 lines] > hence the favorable effect on CVD and blood glucose (in > addition to polyphenols present in some alcoholic beverages). Alcohol raises VLDL1. High risk profile includes a VLDL1 +2 greater than 20 mg/dl Also a VLDL3 small remnant fraction of greater than 10 mg/dl. VAP profile expanded lipid testing. > does beer/wine intake raise VLDL ? Yes. At His service, Andrew -- Andrew B. Chung, MD/PhD Board-Certified Cardiologist ** Suggested Reading: (1) http://makeashorterlink.com/?L26062048 (2) http://makeashorterlink.com/?O2F325D1A (3) http://makeashorterlink.com/?X1C62661A (4) http://makeashorterlink.com/?U1E13130A (5) http://makeashorterlink.com/?K6F72510A (6) http://makeashorterlink.com/?I24E5151A (7) http://makeashorterlink.com/?I22222129 > > does beer/wine intake raise VLDL ? > [quoted text clipped - 3 lines] > > Andrew I agree as stated above. One should obstain from alcohol for lipid profile testing. VLDL is calculated from triglyceride levels and LDL is calculated from incorporating a calculated VLDL. There are three subfractions of VLDL. Large buoyant 1 and 2 and small remnant VLDL3. Br J Nutr. 2000 Jun;83(6):597-604. Related Articles, Links Ethanol with a mixed meal increases postprandial triacylglycerol but decreases postprandial non-esterified fatty acid concentrations. Fielding BA, Reid G, Grady M, Humphreys SM, Evans K, Frayn KN. Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, UK. barbara.fielding@oxlip.ox.ac.uk Plasma triacylglycerol concentrations increase after the acute ingestion of alcohol (specifically ethanol). However, the effect of ethanol when consumed with a mixed meal has not been well studied. The objective of the present study was to determine the perturbations of lipid metabolism that occur after ingestion of ethanol in combination with a mixed meal of specific fatty acid composition. Blood samples were taken from seven healthy male subjects before and after a mixed meal, with and without ethanol. The specific fatty acid composition of the test meal allowed the fatty acids to be traced into the plasma non-esterified fatty acid pool during the postprandial period. Statistical analysis by repeated measures ANOVA showed significant effects of ethanol. For example, postprandial lipaemia was enhanced after the ethanol test meal compared with the control (P < 0.05), mainly due to increases in triacylglycerol-rich lipoproteins in the flotation range Sf 60-400 (VLDL1) (P < 0.05); those in the range Sf 20-60 (VLDL2) and also Sf > 400 (chylomicrons) were not significantly affected. The later postprandial increase in plasma non-esterified fatty acid concentrations was reduced after the ingestion of ethanol (P < 0.001), but the proportions of palmitoleic acid (a marker of fatty acid content of the test meal) and of linoleic acid (a marker of endogenous lipolysis) were not affected. The results suggest a primary effect of ethanol on the stimulation of secretion of large VLDL particles, which then compete for clearance with chylomicrons by lipoprotein lipase. The results do not support an effect of ethanol on the release of non-esterified fatty acid into the plasma. The suppression of plasma non-esterified fatty acid concentrations during the postprandial period may contribute towards the beneficial effects of moderate ethanol consumption. Publication Types: Clinical Trial Randomized Controlled Trial PMID: 10911767 [PubMed - indexed for MEDLINE] > -- > Andrew B. Chung, MD/PhD [quoted text clipped - 9 lines] > (6) http://makeashorterlink.com/?I24E5151A > (7) http://makeashorterlink.com/?I22222129 > > does beer/wine intake raise VLDL ? > > Yes. I agree as stated above. One should obstain from alcohol for lipid profile testing. VLDL is calculated from triglyceride levels and LDL is calculated from incorporating a calculated VLDL. There are three subfractions of VLDL. Large buoyant 1 and 2 and small remnant VLDL3. Br J Nutr. 2000 Jun;83(6):597-604. Related Articles, Links Ethanol with a mixed meal increases postprandial triacylglycerol but decreases postprandial non-esterified fatty acid concentrations. Fielding BA, Reid G, Grady M, Humphreys SM, Evans K, Frayn KN. Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, UK. barbara.fielding@oxlip.ox.ac.uk Plasma triacylglycerol concentrations increase after the acute ingestion of alcohol (specifically ethanol). However, the effect of ethanol when consumed with a mixed meal has not been well studied. The objective of the present study was to determine the perturbations of lipid metabolism that occur after ingestion of ethanol in combination with a mixed meal of specific fatty acid composition. Blood samples were taken from seven healthy male subjects before and after a mixed meal, with and without ethanol. The specific fatty acid composition of the test meal allowed the fatty acids to be traced into the plasma non-esterified fatty acid pool during the postprandial period. Statistical analysis by repeated measures ANOVA showed significant effects of ethanol. For example, postprandial lipaemia was enhanced after the ethanol test meal compared with the control (P < 0.05), mainly due to increases in triacylglycerol-rich lipoproteins in the flotation range Sf 60-400 (VLDL1) (P < 0.05); those in the range Sf 20-60 (VLDL2) and also Sf > 400 (chylomicrons) were not significantly affected. The later postprandial increase in plasma non-esterified fatty acid concentrations was reduced after the ingestion of ethanol (P < 0.001), but the proportions of palmitoleic acid (a marker of fatty acid content of the test meal) and of linoleic acid (a marker of endogenous lipolysis) were not affected. The results suggest a primary effect of ethanol on the stimulation of secretion of large VLDL particles, which then compete for clearance with chylomicrons by lipoprotein lipase. The results do not support an effect of ethanol on the release of non-esterified fatty acid into the plasma. The suppression of plasma non-esterified fatty acid concentrations during the postprandial period may contribute towards the beneficial effects of moderate ethanol consumption. Publication Types: Clinical Trial Randomized Controlled Trial PMID: 10911767 [PubMed - indexed for MEDLINE] > At His service, > [quoted text clipped - 13 lines] > (6) http://makeashorterlink.com/?I24E5151A > (7) http://makeashorterlink.com/?I22222129 Hi Steve, I know exactly how you feel, scary isn't it? I am 50 years old and was diagnosed with High Colestrol, High Blood Pressure and Type 2 Diabetes only 2 months ago, don't panic, worst thing you can do. My doctor prescribed Natrilix SR for my blood pressure, Diabex to lower the glucose level and I cut out anything with sugar in it.Also he suggested a off prescription product called Transfer Factor Plus and TF Cardio. I get a little exercise walking but since taking the Transfer Factor products I bounced back into good health with mountains of energy I have not had since my early 40's.My last patholgy test showed all my levels back to normal.If you would like to know more just drop me a line I'd love to help you if you would like, I feel on top of the world now.JJ "Steve" <billpritjr@spamhole.com> wrote in part: >I just had a annual "lab work" blood test done and observed that my >triglycerides are slightly out of range, higher than normal (300 or so) [quoted text clipped - 8 lines] > >How can one reduce triglycerides? Very high triglycerides (which yours are!) can actually mask high cholesterol. Conventional tests will report your cholesterol to be lower, possibly much lower, than it actually is, based on particle counts. Related to that, high triglycerides are generally a good indicator that HDL is low and that the LDL particle distribuions are more dangerous than normal ("Pattern B"). Reducing carbohydrates, eating fatty fish or taking fish oil supplements, losing weight if you have any excess body fat, etc. can reduce TG. You should follow up with your physician. -- Jim Chinnis Warrenton, Virginia, USA > I just had a annual "lab work" blood test done and observed that my > triglycerides are slightly out of range, higher than normal (300 or so) Not optimal. > while my Chloresterol is 180. The lab results do not delineate "good" > or "bad" cholesterol. That would be unusual since you have been given a triglycerides reading. > I am healthy in all aspects and work out and walk routinely. No fast > foods. > > Is this something to worry about? You might have metabolic syndrome (MetS). > Is a stroke/heart attack/end of the > world pending? If you have MetS, you would be at higher risk for the former two. > How can one reduce triglycerides? By having your MetS addressed. Would suggest you consult your doctor about this possibility. At His service, Andrew -- Andrew B. Chung, MD/PhD Board-Certified Cardiologist ** Suggested Reading: (1) http://makeashorterlink.com/?L26062048 (2) http://makeashorterlink.com/?O2F325D1A (3) http://makeashorterlink.com/?X1C62661A (4) http://makeashorterlink.com/?U1E13130A (5) http://makeashorterlink.com/?K6F72510A (6) http://makeashorterlink.com/?I24E5151A (7) http://makeashorterlink.com/?I22222129 |
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