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Medical Forum / General / Cardiology / November 2004

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CRESTOR ????

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Gary - 25 Nov 2004 15:48 GMT
My cousin's doctor has put him on 10mg of Crestor. I am saying its not smart
to do that in light of the negative discussion going on about that statin.
Even the FDA has Crestor under scrutiny. Therefore, I wonder why the doctor
is pushing Crestor unless he's being influenced by the manufacturer. Is that
possible? If not, why would a physician prescribe a medication that is under
the gun?

Am I right in questioning the use of Crestor, even at a low doses?

Reasoning: There have been reports of excessive cases of kidney damage at
80mg, which is a dose they dropped. Fine. But that does not make me feel
confident that a safer dose, of a potentially harmful drug at a higher dose,
is any better at lower doses, given the cumulative effect of build up in the
body.

Opinion???
outrider - 25 Nov 2004 19:08 GMT
> My cousin's doctor has put him on 10mg of Crestor. I am saying its not smart
> to do that in light of the negative discussion going on about that statin.
[quoted text clipped - 12 lines]
>
> Opinion???

Indeed. Why would a physician prescribe this drug which has no track
record? One reason could be that physicians are being paid to prescribe
it.

Go here and read the article on Crestor:

http://tinyurl.com/3vvj2

http://www.medicationsense.com/articles/july_sept_04/crestor_truth.html

And here re physicians being paid to recruit for pharma:

from the Montreal Gazette.
Tuesday » February 24 » 2004

Cozying up to drug firms disturbs some physicians
Heart doctor complained to professional order after
being invited to refer
patients to clinical trial

CHERYL CORNACCHIA
The Gazette
Tuesday, February 24, 2004

Cardiologist Colin Rose, who also teaches medicine at
McGill, says close
relationships to drug firms undermine doctors'
willingness to try
non-pharmaceutical treatments for their patients.

When a company contacted Colin Rose and offered to pay
him $6,000 to refer
patients to a drug study, they had the wrong doctor.

Rose, a cardiologist at the Montreal General Hospital,
not only said no, but
he passed the written offer to the Collège des
médecins du Québec,
suggesting it investigate the ethics of paying doctors
to refer patients.

"I'm about the last one on Earth they should have
contacted," Rose said
yesterday.

It turns out that the physicians' college doesn't
investigate those kinds of
cases, but the doctor is no less upset by the offer to
send patients to the
study, which was sponsored by Merck Frosst.

Rose, who is also an assistant professor of medicine
at McGill University,
is outspoken about what he sees as an increasingly
cozy relationship between
doctors and drug companies. He says it undermines
doctors' will to suggest
alternatives like lifestyle changes instead of
prescription drugs.

The hypercholesterolemia and coronary heart disease
study to which Rose
referred is being conducted by the Clinical Research
Consultant Group at the
Seaforth Medical Building on Côte des Neiges Rd .

The group's letter to Rose, dated Nov. 18, 2003,
detailed how he would
receive an honorarium of $6,000 if he referred at
least one patient being
treated for high cholesterol and heart disease. He
would have been required
to perform a physical exam of the patients at the
beginning and end of the
study and write the initial prescription. Nurses
employed by the group would
do the rest - seeing patients throughout the 12-week
study.

The study is evaluating the cholesterol-lowering
efficacy of a 10-milligram
dose of a drug called Ezetimibe when given with a
10-milligram or
20-milligram dose of Atorvastatin, another
cholesterol-lowering drug. Both
drugs are approved for use in Canada.

Rose later received an e-mail from Bernice Pynn, the
lead researcher of the
drug study, saying "at this time there is no
discussion of publication" of
the study results. Pynn, a biochemist, was unavailable
for comment
yesterday. However, an assistant at the clinical
research group confirmed
the multisite study is sponsored by Merck Frosst. So
far, she said, 15
patients are enrolled in Montreal.

Vincent Lamoureux, a spokesperson for Merck Frosst in
Kirkland, said doctors
are sometimes compensated for their time. However, he
said, he was
unfamiliar with the study Rose cited, even though
"there definitely seems to
be a link to some of what we do."
Dr. Andrew B. Chung, MD/PhD - 26 Nov 2004 12:56 GMT
> My cousin's doctor has put him on 10mg of Crestor. I am saying its not smart
> to do that in light of the negative discussion going on about that statin.
[quoted text clipped - 12 lines]
>
> Opinion???

Would suggest you let your cousin discuss his/her concerns with his/her
doctor just as s/he would probably let you do the same.


Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/

**
Who is the humblest person in the universe?
http://makeashorterlink.com/?L26062048

What is all this about?
http://makeashorterlink.com/?R20632B48

Is this spam?
http://makeashorterlink.com/?N69721867
outrider - 28 Nov 2004 00:44 GMT
Sure he could Andrew. But people on the patient side of medications
have to get the other side somewhere. Why not from a willing relative
with the time and compassion to do some research and present it, for
his cousin to make the decision? Many people are overwhelmed with the
idea of illness, as well as the effects, let alone having to do all the
research themselves at a stressful time.

I wish I had had someone like Gary to help me out when I needed it. I
may not have ended up in the Baycol mess that brought me here.

Zee
Dr. Andrew B. Chung, MD/PhD - 28 Nov 2004 12:41 GMT
> Sure he could Andrew. But people on the patient side of medications
> have to get the other side somewhere. Why not from a willing relative
[quoted text clipped - 7 lines]
>
> Zee

The concern is that a jaundiced eye is unable to see clearly.

May God bless you on this Lord's day, dear Zee whom I love, in Christ's
precious name.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/

**
Who is the humblest person in the universe?
http://makeashorterlink.com/?L26062048

What is all this about?
http://makeashorterlink.com/?R20632B48

Is this spam?
http://makeashorterlink.com/?N69721867
Gary - 29 Nov 2004 14:21 GMT
I can see what Harvard Medical School is saying. I can see what FDA is
saying in Senate hearing about 7 medication, Crestor being one of them. I
can see where VIOXX was FDA approved and later dropped. So these eyes can
see that having FDA approval is not a guarantee. In statins, there is
choice.

I have a simple question for you.

When you have a fasting blood test, and you get a report with a few things
scrawled on it, like TC, Trig, LDL, HDL, and all the usual culprits, where
is the liver test results. or is that a separate test?

> > Sure he could Andrew. But people on the patient side of medications
> > have to get the other side somewhere. Why not from a willing relative
[quoted text clipped - 31 lines]
> Is this spam?
> http://makeashorterlink.com/?N69721867
Dee Randall - 29 Nov 2004 02:42 GMT
>>Why not from a willing relative
with the time and compassion to do some research and present it, for
his cousin to make the decision? Many people are overwhelmed with the
idea of illness, as well as the effects, let alone having to do all the
research themselves at a stressful time.

I agree.  I don't know what a certain relative of mine would do without his
son to inquire about his medications, keep track of medications he is taking
by putting them in pill boxes, etc etc etc.  God Bless these thoughtful
people.
Dee
 
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