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Medical Forum / General / Cardiology / October 2008

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Question about viral cardiomyopathy

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dudleybates - 25 Oct 2008 15:41 GMT
Hello ...

I have a question about acute (not chronic) viral cardiomyopathy.

I have had a puzzling course of events over the past two months, and
as I'm on Medicare, the sheer number of doctors I've had to see hasn't
helped.

I was exposed to Coxsackie B in August of 2008.  September 1 I was
rushed to the hospital with crushing left substernal chest pain, which
was relieved with sublingual nitroglycerin and profound shortness of
breath, orthopnea and classic paroxysmal dyspnea (PND).  I stayed in
the cardiac unit for three days, with intermittent chest pain.  I also
developed severe flu-type symptoms most GI.  Nuclear stress testing
and contrast CT were negative, and after three days I was discharged.
On the day of discharge I then developed the typical pleuritic chest
pain of Coxsackie B-this time in the right side of the chest, not the
left, which lasted another ten days.  A three day break with no
symptoms, then resumption of pleurisy, this time with fever, for an
additional ten days, put on doxycycline.  My blood tested positive for
Coxsackie B1 viral infection.

I had weakness and shortness of breath but no cardiac-type chest pain
until October 4, at which point my left retrosternal chest pain,
orthopnea and PND returned.  I was referred to cardiology.  It took
another month, but I was told an echocardiogram and angiogram were
eventually "essentially negative" or "not that bad."

I know Coxsackie can affect the heart, and I know that many cases of
viral myocarditis are asymptomatic.  Is it possible that my
retrosternal chest pain could have been caused by the Coxsackie virus,
without evidence of physical degeneration on subsequent tests?  If so,
I thankfully seem to be one of the lucky ones who turned around right
afterwards.

Thank you so much for any light you might shed on this.

best, Helen
Andrew B. Chung, MD/PhD - 26 Oct 2008 22:32 GMT
>Hello ...
>
[quoted text clipped - 23 lines]
>another month, but I was told an echocardiogram and angiogram were
>eventually "essentially negative" or "not that bad."

It has not been a month since October 4.  Perhaps you meant to write
September 4.

>I know Coxsackie can affect the heart, and I know that many cases of
>viral myocarditis are asymptomatic.  Is it possible that my
>retrosternal chest pain could have been caused by the Coxsackie virus,
>without evidence of physical degeneration on subsequent tests?

Yes.

> If so,
> I thankfully seem to be one of the lucky ones who turned around right
> afterwards.

No such thing as luck (Proverbs 16:33).

>Thank you so much for any light you might shed on this.
>
>best, Helen

Laus Deo

<><

"... no one can say 'Jesus is LORD' except by the Holy Spirit." (1 Cor
12:3)

http://groups.google.com/group/sci.med.cardiology/msg/43acbc5ea248ceee?
dudleybates - 28 Oct 2008 18:58 GMT
On Oct 26, 3:32 pm, "Andrew B. Chung, MD/PhD" <ach...@emory.edu>
wrote:

> >I know Coxsackie can affect the heart, and I know that many cases of
> >viral myocarditis are asymptomatic.  Is it possible that my
[quoted text clipped - 21 lines]
>
> http://groups.google.com/group/sci.med.cardiology/msg/43acbc5ea248ceee?-

Thank you very much for your input!  I was exposed to Coxsackie B1
during the month of August, specifically between August 10 and August
21.  My symptoms started September 1 with sharp/crushing left
retrosternal chest pain, paroxysmal nocturnal dyspnea, orthopnea,
profound weakness, headache and GI flu symptoms.  The retrosternal
chest pain--relieved by nitroglyerin--became intermittent and resolved
after three days, after which it was replaced by right chest pleurisy
(epidemic pleurodynia typical for Coxsackie B), with intermittent
fever for the next 20 days.  There was one more episode of
intermittent left retrosternal chest pain which lasted for several
days (October 4), again responsive to nitro.  PND was instantly
responsive to furosemide.  However, both angiogram and echocardiogram
were normal, with normal left ventricular ejection fraction.

The cardiologist told me the retrosternal chest pain was not related
to the Coxsackie at all ... however, everything I've read tells me it
probably was, and I felt I could probably find the truth here.

I am left with the paroxysmal nocturnal dyspnea, which is terrifying.
The cardiologist stopped the furosemide, because I have a normal LV
ejection fraction.  I am therefore exploring the possibility that the
PND could be related to pulmonary causes, and will discuss it with my
new primary MD.

Thank you all very much for your help.

best, Helen
Andrew B. Chung, MD/PhD - 29 Oct 2008 09:15 GMT
> Andrew, in the Holy Spirit, boldly wrote:
> > neighbor Helen wrote:
[quoted text clipped - 19 lines]
>
> Thank you very much for your input!

Again, Laus Deo :-)

> I was exposed to Coxsackie B1
> during the month of August, specifically between August 10 and August
[quoted text clipped - 9 lines]
> responsive to furosemide.  However, both angiogram and echocardiogram
> were normal, with normal left ventricular ejection fraction.

Suspect the problem has been diastolic dysfunction.

> The cardiologist told me the retrosternal chest pain was not related
> to the Coxsackie at all ... however, everything I've read tells me it
[quoted text clipped - 5 lines]
> PND could be related to pulmonary causes, and will discuss it with my
> new primary MD.

It is likely that the PND is related to diastolic dysfunction in the
setting of a normal left ventricular ejection fraction.

> Thank you all very much for your help.

Again, Laus Deo :-)

Prayerfully in the awesome name of our Messiah, LORD Jesus Christ,

Andrew <><
--
"... no one can say 'Jesus is LORD' except by the Holy Spirit." (1 Cor
12:3)

http://groups.google.com/group/sci.med.cardiology/msg/43acbc5ea248ceee?
dudleybates - 27 Oct 2008 22:30 GMT
> I have a question about acute (not chronic) viral cardiomyopathy.

argh ... make that acute viral myocarditis, of course, not viral
cardiomyopathy.  mea culpa.
asiandollno1@gmail.com - 28 Oct 2008 09:54 GMT
Your retrosternal chest pain might have been caused by the Coxsackie B
virus as its symptoms include fever, headache, sore throat,
gastrointestinal distress, as well as chest and muscle pain. If you
are suffering from chest pain I encourage you to see a doctor
immediately because viruses in the Coxsackie B family progress to
myocarditis or pericarditis, which can result in permanent heart
damage or death. The incubation period for the Coxsackie B viruses is
highly variable, ranging from 2 to 35 days, and illness may last for
up to two weeks, but may resolve as quickly as two days. Infection
usually occurs between the months of June and October.

For your information as of 2008, there is no well-accepted treatment
for the Coxsackie B viruses, although there are homeopathic remedies
which may treat the infection. Palliative care is available, however,
patients suffering chest pain or stiffness of the neck should be
examined for signs of cardiac or central nervous system involvement,
respectively. Some measure of prevention can usually be achieved by
basic sanitation on the part of food-service workers, though the
viruses are highly contagious. Care should be taken in washing ones
hands and in cleaning the body after swimming. In the event of
Coxsackie-induced myocarditis or pericarditis, antiinflammatories can
be given to reduce damage to the heart muscle.

AsianDoll

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