> I'm barely taking any Cortef.. just 2mg a day even though my doc told me to
> take 15mg a couple weeks ago (as did the doc before him). I'm trying to work
> up, honestly. Its just a bit scary to think that my adrenals are really this
> bad and that I might need this for the rest of my life.
> x-no-archive: yes
>
[quoted text clipped - 5 lines]
> Have you had imaging studies of your adrenals and your pituitary with
> and without contrast?
I recently had a CT of my adreanals without contrast. It was clear of
anything grosly abnormal. I've also had a lot of blood tests like ACTH,
prolactin, aldosterone, DHEA, DHEAs, etc. all normal except when I'm taking
testosterone cream for low testosterone (then DHEA becomes elevated).
> > One thing I noticed today was that my eyes were very bloodshot, then just 30
> > minutes after taking 2mg of Cortef, they were completely clear. Somewhat
[quoted text clipped - 3 lines]
> exercise or anything else, like illness, for example. Have you had 24
> hour urine, saliva and serum testing?
Yes, I've had both saliva and 24-hour urine. The saliva test showed higher
than normal morning cortisol, and flag (near zero) for the rest of the day.
The 24-hour urine had a reference range of 0 to 50, mine was 4. Afternoon
serum cortisol was always 10% above the bottom of the reference range.
> > My aldosterone was normal and I don't have postural hypotension, so I guess
> > Florinef wouldn't help? My blood pressure is just constantly low (for me). I
[quoted text clipped - 7 lines]
> Cushing's patient (as I am) and dip very low when you stop oversecreting
> ACTH.
That's interesting. I will check that message board out.
Thanks,
Richard
> Susan
Susan - 08 May 2008 14:42 GMT
> I recently had a CT of my adreanals without contrast. It was clear of
> anything grosly abnormal.
It requires contrast for better accuracy. Even then, I know folks
who've had adrenalectomy and the glands the surgeons found were much
larger and more abnormal than imaging indicated.
I've also had a lot of blood tests like ACTH,
> prolactin, aldosterone, DHEA, DHEAs, etc. all normal except when I'm taking
> testosterone cream for low testosterone (then DHEA becomes elevated).
Here's the thing about ACTH; it's briefly pulsed, disappears from the
blood within minutes and requires extremely special handling by the lab
that they never do. It must be drawn into a chilled tube, placed
immediately into an ice water bath, centrifuged in a chilled bath and
frozen all within 7 minutes, no touching the tube with hands, might warm
it. It breaks down very quickly. Also, midnight serum and saliva
cortisol is very useful.
> Yes, I've had both saliva and 24-hour urine. The saliva test showed higher
> than normal morning cortisol, and flag (near zero) for the rest of the day.
> The 24-hour urine had a reference range of 0 to 50, mine was 4. Afternoon
> serum cortisol was always 10% above the bottom of the reference range.
You need midnight serum, and maybe 10 hour UFC (10pm to 8 a.m.).
>>Visit the message boards at cushings-help.com. There's more than just
>>Cushing's discussed, including Addison's. You may be a cylical
>>Cushing's patient (as I am) and dip very low when you stop oversecreting
>>ACTH.
>
> That's interesting. I will check that message board out.
Good luck.
My bp drops to 90/53 when I'm very low on cortisol, too.
Susan