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Medical Forum / General / Cardiology / March 2008

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N-acetylcysteine helps the kidneys remove homocysteine?

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Pramesh Rutaji - 30 Mar 2008 19:39 GMT
I recently came accross information that seems to say that
N-acetylcysteine is effective in modifying homocysteine and consequently
 facilitating it's remove by the kidneys.  Anyone have any information
or experienced with this?

I'm also trying to find out if L-tryptophan can increase homocystiene
given that "Methionine is one of only two amino acids encoded by a
single codon (AUG) in the standard genetic code (tryptophan, encoded by
UGG, is the other)." http://en.wikipedia.org/wiki/Methionine

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Pramesh Rutaji

p297tongue6221@newsguy.com - remove tongue to reply

Marshall Price - 30 Mar 2008 21:38 GMT
> I recently came accross information that seems to say that
> N-acetylcysteine is effective in modifying homocysteine and consequently
[quoted text clipped - 5 lines]
> single codon (AUG) in the standard genetic code (tryptophan, encoded by
> UGG, is the other)." http://en.wikipedia.org/wiki/Methionine

I just took some n-acetylcysteine last night to see whether I could do
more pushups without fatigue.  I tried this morning, and I think it
helped, but I can't say for sure yet.  The bottle of pills I have is
past its expiration date.

...

I did about five sets of ten this morning, and just did another set of
ten pushups, and I think it felt better than usual.

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Marshall Price of Miami
Known to Yahoo as d021317c

trigonometry1972@gmail.com | - 31 Mar 2008 00:33 GMT
> > I recently came accross information that seems to say that
> > N-acetylcysteine is effective in modifying homocysteine and consequently
[quoted text clipped - 19 lines]
> Marshall Price of Miami
> Known to Yahoo as d021317c

The very fact you are taking it in tablets or capsules suggests a tiny
to small dose. I doubt that NAC has any problem when past the
so-called expiration date. Expiration dates are based in regs
and broad generalities and not the specifics of this chemical.

And to the first poster, I'll suggest methionine getting combined
in a polypeptide takes it out of the homocysteine cycle for at least
a span of time. If you're worried add in some betaine (N-
trimethylgylcine)
to your intake as that will keep the homocysteine levels low and it
isn't dependent on
having good genetics involved with the handling of folic acid.
I don't think tryptophan will raise or lower homeocysteine levels much
on first blush response.
Marshall Price - 31 Mar 2008 11:59 GMT
>>> I recently came accross information that seems to say that
>>> N-acetylcysteine is effective in modifying homocysteine and consequently
[quoted text clipped - 22 lines]
> so-called expiration date. Expiration dates are based in regs
> and broad generalities and not the specifics of this chemical.

The bottle says that the tablets contain 600mg each of
"N-Acetyl-L-Cysteine."  I just took one, on an empty stomach, as the
bottle suggests.  It also suggests taking one to four tablets a day, "or
as directed by your qualified health consultant."

One of the first things that really worried me (recently) about my
health was that I found it hard to wield a hammer overhead.  When I was
young, it was never a problem.  I could keep it up all day.  But one day
about six months ago (after not having done that kind of work for
years), I found a muscle in my arm getting sore very quickly --
alarmingly so!

The quoted text from that article from newsrx.com (which I can't find
online) was the first hint to me that N-acetylcysteine might help.  I've
never heard of "fatigue therapy" before.

I hope they're not going to patent that information.  There's been a lot
of controversy about such things recently.  (Michael Crighton
contributed an op-ed essay to the New York Times in which he illegally
divulged a simple scientific fact, if I recall correctly.)

Incidentally, I've done a few more sets of pushups since, and though
this transient muscle soreness problem seems to come and go by itself,
it's definitely gone now.

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Marshall Price of Miami
Known to Yahoo as d021317c


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