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Medical Forum / Diseases and Disorders / Cancer / February 2005sigmoid carcinoma
Hello all, I posted my questions few days ago with regard to sigmoid colon cancer of my mother, living in Ukraine. Here are more details: My mother was fistly diagnosed with carcinoma 2 years ago. The tumor was resected. Last summer another tumor was discovered roughly on the same place- i.e in the vicinity of the resected area of the sigmoid colon. There is 1 methastastic tumor right in the "wall of peritoneum" (I don't know the exact translation of this term - this is a word-to-word translation). In October the sigmoid colon was resected again and that tumor was successfully removed. Unfortunately, the secondary (that one in the peritoneum) tumor turned out to be unremovable- it grew through the wall and was "not movable" (again, literally what Dr's said) . Size of this timor is about 60 mm X 60 mm The questions are following: 1) Would the High Frequency hyper-thermy therapy be of any help in the given circumstances? 2) chemo is still the same - 5FU. does it make any sense if the tumor is in the different place now? In priciple radiation therapy is available, but the Dr's said it is not recommended as it would damage (burn) surrounding healthy colon tissue. Dima > Hello all, > [quoted text clipped - 15 lines] > 1) Would the High Frequency hyper-thermy therapy be of any help in the > given circumstances? No > 2) chemo is still the same - 5FU. does it make any sense if the tumor is > in the different place now? Chemo is not the appropriate treatment. What do you expect it to achieve? > In priciple radiation therapy is available, but the Dr's said it is not > recommended as it would damage (burn) surrounding healthy colon tissue. If the residual disease is causing symptoms, local radiotherapy is exectly the correct treatment. Unfortunately, nothing is likley to cure this situation > Dima Thanks to everyone who responded, > Chemo is not the appropriate treatment. What do you expect it to achieve? I think Dr's are trying to slow down further growth of the tumor. Althogh I assume I don't know all the details. Dima > I posted my questions few days ago with regard to sigmoid colon cancer > of my mother, living in Ukraine. [quoted text clipped - 9 lines] > the wall and was "not movable" (again, literally what Dr's said) . > Size of this timor is about 60 mm X 60 mm Hello Dima, I'm sorry to read that the cancer seems unstoppable. Can you get a second opinion from a radiation oncologist? (see Steph's reply) Please keep in touch J Hello everyone, Just general questions with regard to Photo-Dynamic Therapy: How widely is it used in North America? Is it effective at all? Was there any considerable progress in the research in this field in the recent years? I have background in laser physics myself. Now , due to very sad circumstances, I became interested in it ... Dima > Hello everyone, > [quoted text clipped - 8 lines] > > Dima Take a look here: http://cis.nci.nih.gov/fact/7_7.htm http://www.cancerbacup.org.uk/Treatments/Photodynamictherapy/PhotodynamicTherapy http://www.cancer.org/docroot/ETO/content/ETO_1_3X_Photodynamic_Therapy.asp Jerry > Hello everyone, > [quoted text clipped - 8 lines] > > Dima What for? It has very limited usefulness > "D" <dboldovsky@yahoo.com> wrote in message >>I have background in laser physics myself. Now , due to very sad >>circumstances, I became interested in it ... >> >>Dima > > What for? It has very limited usefulness I know. Just general interest. A long time ago I was about to enter a PDT research project. Apparently it has not much been of a progress since then.. Dima TARGET .. the .. iron .. http://herbivore.7h.com/cancerpost.html Nutr Cancer. 2004;48(1):1-5. Related Articles, Links A hypothesis: interaction between supplemental iron intake and fermentation affecting the risk of colon cancer. The Iowa Women's Health Study. Lee DH, Jacobs Jr DR, Folsom AR. Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA. Fermentation in the large intestine can increase absorption of ferrous iron, which is the main form in supplements, because the solubility of ferrous iron is enhanced in the mildly acidic environments caused by fermentation. We therefore hypothesized that higher supplemental iron intake would increase the risk of colon cancer among those who consume large amounts of fermentable substrates, namely, dietary fiber and resistant starch. Among 34,708 postmenopausal women, supplemental iron was unrelated to proximal colon cancer in all women and to distal colon cancer among those consuming below the median of fermentable substrates. However, supplemental iron was positively associated with distal colon cancer among women who consumed above the median of fermentable substrates (P for interaction %lt; 0.01); the adjusted relative risks across categories of supplemental iron (0 g/day, 1-19 g/day, 20-49 g/day, and > or = 50 g/day) were 1.0, 1.24, 1.78, and 3.78 (P for trend < 0.01). This hypothesis needs confirmation in other cohort studies because, despite the significant trend, only nine cases were included in the top category of > or = 50 mg supplemental iron, and this finding could have arisen by chance. Copyright 2004 Lawrence Erlbaum Associates, Inc. PMID: 15203371 [PubMed - indexed for MEDLINE] -------------------------------------------------------------------------------- J Natl Cancer Inst. 2004 Mar 3;96(5):403-7. Related Articles, Links Heme iron, zinc, alcohol consumption, and colon cancer: Iowa Women's Health Study. Lee DH, Anderson KE, Harnack LJ, Folsom AR, Jacobs DR Jr. Department of Preventive Medicine, College of Medicine, Kyungpook National University, Daegu, Korea. We examined associations among colon cancer incidence and dietary intake of heme iron, a possible prooxidant, zinc, a possible antioxidant, and alcohol, a disruptor of iron homeostasis. During 15 years of follow-up, 34 708 postmenopausal women, aged 55-69 years at baseline who completed a food-frequency questionnaire for the Iowa Women's Health Study, were followed for incident colon cancer. After adjusting for each micronutrient, the relative risks for proximal colon cancer increased more than twofold across categories of heme iron intake (P(trend) =.01) and the corresponding relative risks decreased more than 50% across categories for zinc intake (P(trend) =.01). The positive association with heme iron and the inverse association with zinc intake were stronger among women who consumed alcohol than among those who did not. Zinc intake was also associated with a decreased risk of distal colon cancer (P(trend) =.03), regardless of alcohol or heme iron consumption. Our results suggest that intake of dietary heme iron is associated with an increased risk of proximal colon cancer, especially among women who drink, but that intake of dietary zinc is associated with a decreased risk of both proximal and distal colon cancer. PMID: 14996862 [PubMed - indexed for MEDLINE] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice > TARGET .. the .. iron .. --- "Iron excess causes diabetes, renal/kidney disease, mental illness and especially *free radicals*. THIS is why Jesus espoused *vegetarianism*." Tom Hennessy, 1997/05/07: rec.food.veg [Now ironjustice@aol.com] >> TARGET .. the .. iron .. > > --- > "Iron excess causes diabetes, renal/kidney disease, mental illness > and especially *free radicals*. THIS is why Jesus espoused *vegetarianism*." > Tom Hennessy, 1997/05/07: rec.food.veg [Now ironjustice@aol.com] In Tom's quack remedy he states iron causes cancer and must be removed from the patient with bloodletting. The Austrian faith healer, R.A. Hoffmann, in his quack remedy The Iron Cancer Cure, the patient must take doses of iron to cure cancer. Much of alt med is full of similar contradictions. I wish the alt med lunatics would at least read up before they announce their miraculous discovery. They might see that someone else has already exploited that angle. They might also save themselves a lot of embarrassment. Jerry http://herbivore.7h.com/cancerpost.html Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking I notice you didn't say a whole helluva lot about signoid carcinoma .. Eh .. 'J' .. How's that .. feel .. To BE .. such .. a .. friggin .. loser .. Eh .. Heh .. heh .. Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking |
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