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Medical Forum / Diseases and Disorders / Cancer / May 2005c reactive protein and lymphoma
Does c reactive protein become elevated in lymphoma? I had a high crp of 54 one week. The next week it was 1.1 which was in the normal range. I had a fever before each test. Why would this be? > Does c reactive protein become elevated in lymphoma? I had a high crp > of 54 one week. The next week it was 1.1 which was in the normal range. > > I had a fever before each test. Why would this be? It's an entirely non-specific test. Are there any tests you haven't had? What do you mean it is non specific? What do you mean "are there any I have not had"? > What do you mean it is non specific? > > What do you mean "are there any I have not had"? Rather than post an endless list of questions about tests, why don't you tell us your medical problem and what the doctors you have seen have said? Hello, I am glad that the next value of CRP was not elevated.It is not usually elevated in lymphoma,CRP shows the degree of inflammatory processes in the body.What about CBC(complete blood count)?Was it normal?ESR?Do you have any more scheduled tests?If you have reccurent flu-like episodes,obviously that you must be thorougly medically examined,and that the cause of such condition must be found.I sincerely hope all goes wel.Best of luck. So CRP is not elevated in lymphoma? I will explain my situation: I am 33 and male. In December of 2003, I weighted about 210. I got a case of the flue and it knocked me in bed for about 5 days. After this was over, I started eating a low carbohydrate diet. I noticed about 2 or three months after that that I developed a fever, got cold and had aches and chills just like the flu. It would come on suddenly and last about a day. The next day I would feel fine. This would happen every three to 4 months. I really just though my system was figting a bug or something. It happened again two weeks ago and I went to the doctor. They did a cbc tested me for hiv, rocky mountain spotted fever, epstein bar virus,cytomegalo virus. It all came back negative with the exception of my c reactive protein which was very high, it was 54 with 0 to 4 being normal. My percentage of lympochtes were a little low and my granuocytes were a little high. My white count was 9.8 which was in the normal range but I guess the high side of normal. This was on a Thursday. The following Monday (this past Monday) I saw an infectious disease doctor. I still had a fever when she checked me of 99.7. She took blood and did another crp and also checked for histoplasmosis. The crp was now normal at 1.1. (The hysto has not come back yet.) She immediately said because of my age she was worried about lympoma. I am scheduled for a gallium scan on Monday. The other thing that bothers me is I have been off that diet for sometime now and I still seem to be losing weight. I weighted 173 or so at my mom's today. To be fair I have not ate much this week because I am worried about all this but that is alot of weight. This is what the cbc looks like: Patient Limits 3 Wbc 9.8 x10^3/uL 4.5-10.5 LY 14.1 L % 20.5-51.1 MO 2.7 3 % 1.7-9.3 GR 83.2 3H % 42.2-75.2 LY# 1.4 x10^3/UL 1.2-3.4 MO# 0.3 3 x10^3/uL 0.1-0.6 GR# 8.2 3H x10^3/uL 1.4-6.5 RBC 4.78 x10^6/uL 4.0-6.0 Hgb 14.1 g/dl 11.0-18.0 Hct 42.1 % 35.0-60.0 MCV 87.9 fl 80.0-99.9 MCH 29.5 pg 27.0-31.0 MCHC 33.5 g/dl 33.0-37.0 RDW 13.7 % 11.6-13.7 PLT 171 x10^3/uL 150-450 MPV 7.9 fL 7.8-11.0 Any help is appreciated! This is indeed a substantial weight loss.But,weight loss could indicate number of conditions,not just cancer.Before your troubles started,have you been exposed to some infectious agent that you know of?Do you have any GI symptoms?Regarding CBC-it is a normal CBC,slightly lower Ly number is not worrying.ESR(erythrocyte sedimentation rate)?Did they check it?Regarding Gallium scan-yes,they can see enlarged lymph nodes.The precise name of the exam is Gallium-67 whole-body scintigraphy(it is a specific type of exam for the diagnosis of lymphoma).I keep my fingers crossed for you,I would like to know the outcome.One advice:try to calm down,excessive stress can lead to weight loss.If Ga scan is negative,which I hope it is,than further tests should be done. Sorry, i just saw your other postings regarding your problem.First of all,Gallium scan is a specific type of test to check for lymphoma(of course,there is something better,called PET san,but it is very expensive type of test).CT and Magnetic resonance imaging can also be done.Nevertheless,Ga-67 scintigraphy is specific for lymphoma,your doctors know what they do!!Secondly,if you have had colonoscopy,no need to wory about the rectal lump-that certainly can not be lymphoma.More likely that it is due to haemorrhoids.It seems to me that you are very scared,and that you are searching for some signs of lymphoma-my advice,don't do it,because it will exhaust you mentally.Wait for Ga scan results,and try to relax in the meantime. I guess they did not do a sedimintation rate. What is that? The lump was not there during the colonoscopy. It appeared about 5 months later. What do you mena "exposed to infectious agents?" Not that I am aware op. I am scared. I have a wife, 5 year old daughter and 4 month old son, I am only 33. I am so scared! 3 years ago I started having abdominal bloating and contipation all of a sudden. Last year I had a colonic transit study where they took an abdominal x ray every day for 4 days. It showed i have slow transit in my ascending colon. Erythrocyte sedimentation rate is a blood test that is indicator for inflammation,possibly cancer,and numerous other conditions.When I said exposed to infectious agents,I meant-did you maybe have a bad meal,kissed some pet,swim in lake.Infectious agents(blood,tissue or intestinal parasites or pathogenic bacteria or viruses) sometimes can provoke these responses,ie. fever.It is important that you developed abdominal bloating and constipation,very important information.Lets wait for Ga scan results,I do believe it would be negative.If so,regarding that you do have GI complaints(how did I know about that,ask yourself-I am not magician),further testing would be necessary.Try to relax,I am pretty convinced you don't have cancer.I know that you are scared for your family,but try to relax-no bad findings so far.Good luck tomorrow. Why is the constipation important? I have had a normal colonoscopy and barium enema. Thanks for hte reasurring talk. You are a nice person to talk to. Why do you think I dont have it? Do you know what polycythemia is? My grandfather died of it at 67, he had it for about 15 years. He died before I was born. Am I prone to lymphoma because of that? But an infectious agent like that would not cause a periodic fever for over a year would it? The only thing I can think that happened after two of the fevers were they came on after workig hard outside, once, after working in my yard and waxing my wife's car and one time (this last time) at my mom's trying to take off a stuck part on my dad's bushhog by hitting it with a large railroad tie. But , I have had many other fevers that came suddenly when I was not working outside I think. You are welcome,I know what fear is,specially regarding the fact that you have a wife and two children.I don't think you have lymphoma because,to be true,there would be more signs.Did they do simple chest X-ray?Lymph nodes can be seen on that X-ray,as well as on abdominal and pelvic ultrasound. You don't have polycythemia.It can be clearly seen from your CBC(your RBC, Hgb and Platelet count are normal,not elevated),and there is no link between polycythemia and lymphoma.There could be other signs of it(like splenomegaly-enlarged spleen),but you probably had a decent physical exam to rule that out-spleen can be palpated.Did you tell your doctor about your grandfather? Infectious causes would be able to cause symptoms like these,and GI symptoms may be linked to it.Lets just wait for Ga scan results,and than other steps may be considered.Best of luck. > So CRP is not elevated in lymphoma? > [quoted text clipped - 49 lines] > > Any help is appreciated! I really dpon't see anything which suggests you have lymphoma Thanks for the input guys and gals. I have not had a chest x ray since 99. I did put on my form about my grandfather. The weight loss really has me scared. I am so upset right now. I showed up at the hospital for my gallium scan and they did not have the right type of gallium the docotr wanted me to have. So, they will have to inject me tomorrow which means it will be another week before I know anything. Why cant I just have a ct scan? WOuld it show the same thing? Not necessarily.You see,Gallium-67 whole body scintigraphy detects possible lymphoma in the whole body,while CT detects it only in the area of scanning(and,besides that,even with the newest multislice CT scanners you get huge amount of radiation).I am sorry that you have to wait for another week,but,as I said,I really don't believe that you have lymphoma.There is now available newest MRI scanner,"Magnetom avanto" at 1.5T that can scan the whole body,from head to toe,with one dose of gadolinium contrast,in just 12 minutes,but not many Clinical Centers in the world has it.I suggest that you wait,and we will see the outcome,I am pretty sure that everything is Ok and you don't have cancer. Thinking about going to my family doc and having a chest x ray to ease my fears. (Maybe). WOuld this be prudent? Because you are so upset over the whole thing(and I can understand that),that may be the good idea.You can ask him to do a chest X-ray(to be sincere,I am a bit surprised that your doctor didn't perform it in the first place).Thoracic lymph nodes,mediastinal lymph nodes can be easily seen that way.I think you will ease your fears.Let me know what is going on.In the mean time,try to relax a bit. Welll, I dont know if I feel better or not. I went to a general family doc. I explained that I had a cought and sore throat, (which I do right now). When I went in I had a fever of 100. I did not know I STILL had a fever. I also explained my worry about the lymphoma and asked for a chest x ray. He had someone take me into the x ray room and had me stand with my chest against a board. They took a picture. Then I stood with my side against the board with my hands up in the air and took a picture. I was escourted back to a room and they shut the door. I heard the doctor talkign into a recorder looking at my x ray (he used my name when he was talking). All I heard him say was my name and something about the lungs being "full of breath or air". I heard the recorder be clicked off. A minute or two latter I heard him say "Oh no!" A few minutes after this he came into my room and quickly said "looked normal". I said "that makes me feel better". He then said, "jest between me and you, you could probably go to xyz center and get that gallium scan quicker than by waiting on the Medical Center. I have the same trouble each time I send someone for a PET, Gallium, MRI, or whatever to The Medical Center. I bet xyz center could even get you in this week. I started feeling a little funny and I asked him again. "But the x rays were normal, right?" He said yes. I am probably splitting hairs, but would a doctor just tell someone that just because they knew they were going to get a scan from another doctor anyway, so that doctor did not have to deliver any "bad news"? Why do I still have a fever? Ok,I think that you are a bit overreacting now.What you have heard him saying,maybe was related to something else,not your X-ray.They have to tell you the truth-no one is entitled to hide the truth from the patient.Regarding fever-well,that is a question for which answer must be found,right?I suggest that you wait for the Gallium scan,I still think it will be OK.Try to relax a bit now,when you know Chest X-ray is normal. You are probably right. One thing the doctor told me when I asked about c reactive protein is he said it is always elevated in lymphoma. I have heard on the web the opposite. Do most lymphmas begin in the chest? Not necessarily,but very frequently.C-reactive protein is showing just a degree of inflammation,it is not specific regarding lymphoma.I suggest you try to ease up now,since lymph nodes in the chest are not enlarged.In case of lymphoma,they would have been enlarged,at least some of them.I understand that you are concerned because of your family,but I also believe that panic leads nowhere-in fact,it is a shortcut to hell.Take care,and best of luck. What do you mean "shortcut to hell"? Not literally,but panic can exhaust you mentally,and that is road to hell.Calm down,no need for panic. I am just scared. I still have a fever and feel crappy. I am sick at my stomach too. Is there an easy way to tell if that rectal lump is or is not a lympre node? I know yhat you are scared,but,as I told you,no need to be scared that much.I believe that your family wouldn't like to see pater familias scared.Yes,there is an easy way for the rectal lump-visit gastroenterologist,and he will palpate it with the finger.Besides,in the area( as much as I can understand,it is not rectal,but perianal lump) there are not lymph nodes which can generate lymphoma. Your sickness at stomach resembles me to some infectious agent.If your Gallium scan is negative,visit infectious dieases doctor,tell him about your stomach discomfort,and ask for 3 consecutive stool samples for Ova and parasites to be done,collected in liquid fixative.Also stool culture.Best of luck. So, these lymph nodes are outside the anal opening? I went to a gastroenterologist last year. Explained the lump. He looked with an anoscope but could not see it he said. It is about tinches up the anal cannal I think. Went for Gallium scan today. It showed all my internal organs. They said might be able to see the lymph nodes tomorrow. Can your lympth nodes hurt after being injected with that stuff? Why would that be? On a side note this may not be related to anything, but I went through a period of where I could take very few drinks of alchol and it would flush my face and turn it red. Would that be related to my current problem? I am sorry for getting all worked up. I thought I found a swollen lympth node last night and broke down and cried. How do you know so much about lympthphoma? Just curious. Please,just try to relax.Your bloodwork is really not indicative on lymphoma,and you are just trying to find anything that may look like enlarged lymph node-you are not a doctor,you don't know how lymph node is palpated!Wait for the Gallium scan results,it will give your doctors some clues,possibly regarding further testing.You will not alleviate your symptoms by driving yourself into extreme anxiety,neither you will help your family. I am just scared. I have been having nite sweats too. I appreciate your pateints and any prayer you could offer. How do you know so much about lymphoma? I will pray for you,I think everything will go well.Never mind about my knowledge-does it matter?I am not here to brag about anything,but to help if I can.You are having nite sweats?That could be due to anxiety.Did you tell your doctor about it?You should tell the doctor about nite sweats,it is very important information.Just try to relax a bit,panic attacks really aren't helpful. Why are night sweats important information? I have had them before but they seem worse recently. They are never "soaking" like I have read about with lymphoma. Do you still feel the Gallium scan will be negative? It may be that nite sweats have nothing to do with lymphoma(to be sincere,once again,there is not a single indication that you have lymphoma),but all the symptoms must be reported to the doctor.Yes,I feel that Gallium scan will be negative. > It may be that nite sweats have nothing to do with lymphoma(to be > sincere,once again,there is not a single indication that you have > lymphoma),but all the symptoms must be reported to the doctor.Yes,I > feel that Gallium scan will be negative. Not much point having one if your feelings will do, is there? What is your problem?What should I say-that I feel that he does have lymphoma?Well,maybe...just maybe you are an oncologist-which certainly doesn't make you human.Go play with your toys....and leave me,"gifted amateur" alone(not even Ph. D's will do these days,I guess). I went for the gallium scan today. They want me to come back so they can focus on my abdomen. (Still had dye left over) Does anyone know are your lympth nodes supposed to show up on a gallium scan, even if there is nothing wrong with them? Steph, What is the Gallium immage supposed to look like in terms of the bone? Is your spine supposed to show? DO you know? > Steph, > > What is the Gallium immage supposed to look like in terms of the bone? > Is your spine supposed to show? DO you know? All a gallium scan shows is where white blood cells are collecting. Sure it can be positive in lymphoma, but in lots of other things too. Unlike idiot Danny suggests, it is NOT a specific test for lymphoma. http://my.webmd.com/hw/health_guide_atoz/hw214778.asp Oh,oh..someone is getting nasty..IS THERE BIGGER IDIOT HERE THAN YOU,YOU FILTHY CLOWN?? > Oh,oh..someone is getting nasty..IS THERE BIGGER IDIOT HERE THAN > YOU,YOU FILTHY CLOWN?? Grow up, you 8 year old Try to consult a shrink.Might help. > Try to consult a shrink.Might help. If you were intelligent, what would you post next? And,something more..I didn't suggest the Gallium scintigraphy is specific for lymphoma.I said in one of the previous postings that it picks up around 80% Hodgkins or Non-Hodgkins lymphomas.But,as you said,libel is a very dangerous toy.See you,very soon,on that account. > And,something more..I didn't suggest the Gallium scintigraphy is > specific for lymphoma.I said in one of the previous postings that it > picks up around 80% Hodgkins or Non-Hodgkins lymphomas.But,as you > said,libel is a very dangerous toy.See you,very soon,on that account. Bring it on, sonny Stryped, If you are smart, you will listen to Steph. Hes a doctor and smart. I have lymphoma. I was diagnosed in 2000. I had enlarged Lymph nodes along my intestinal track. NO where else. they found them by accident in a CT scan I had for abdominal pain (which was not related to the lymphoma). The only way the could determine if it was Lymphoma was having a Biopsy done on those enlarged lymph nodes. try and relax and wait for your reports. Best of luck to you. Rose Did you have a gallium scan? > Did you have a gallium scan? Do you understand what a gallium scan can and cannot do yet? No, could you explain to me the difference? (Between that and a gallium scan?) Ok, I know that a gianosis of lymphoma can only be done with biopsie. But cant the gallium scan show where the biopsie would be needed. Since they said I had a spot come up on my lung, could that be a lymph node on my lung? (Are there lymp nodes on the lung?) or WIll a gallium scan show an infection or other malady in the lung itself? I am slowly learning about this. I appreciate your education. If they did a ct scan of my lungs, what would that show that the gallium could not? First I had a Ct scan then I had a biopsy, then I had 6 months of chemo, then I had several more ct scans, then I had a PETscan. In my opinion the Pet scan is better than the Galluim. I have doctors that are kept very well informed and up to date. every visit they tell me there is something new I can try next time my Lymphoma starts growing again. Also you have Lymph nodes all over your body, It's called the Lymphatic system. they filter out germs and fight virus. Its part of your imune system. I had NO symtoms with my Lymphoma. as I stated before they found it by accident. Good luck. Rose How many lympth nodes were involved? Where were they? How old were you when you were diagnosed? <snip How many lympth nodes were involved? Where were they? How old were you when you were diagnosed? Stryped I never ask for a total count of enlarged lymph nodes. when your told you have Lymphoma you really dont give a dam. my lymph nodes that were involved were in my abdomin. I was almost 50 years old. Doc said I could have had these for years, I had no symtoms, and my Lymphoma is indolent t-cell which wouldnt mean anything to you unless you have researched ALL kinds of Lymphomas and understand what they are and do. You should be asking your doctor these questions. enlarged Lymph nodes doesnt mean Lymphoma, could be an infection somewhere. best of luck. Rose > I am just scared. I have been having nite sweats too. If you keep up this constant worrying you'll die a thousand deaths before you ever get any report back from the Dr. Sounds to me like you have/had a viral infection and not cancer. My sympathies to your wife. > Thinking about going to my family doc and having a chest x ray to ease > my fears. (Maybe). WOuld this be prudent? Who is ordering all the complicated investigations? > Thanks for the input guys and gals. > > I have not had a chest x ray since 99. I did put on my form about my > grandfather. But you're having a gallium scan? That's a.s-backwards. > The weight loss really has me scared. > [quoted text clipped - 4 lines] > > Why cant I just have a ct scan? WOuld it show the same thing? What do you mean? |
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