A good friend had external radiation without chemo 3 years ago. 35-40
treatments following an increasing PSA. At that time he was 80 years old.
I don't know what PSA dropped to after treatment. But after 1 1/2 years his
PSA has risen (every 6 months tested) to 15. At his age his Urologist has
not suggested doing anything saying "at your age it won't be cancer that
kills you". This man is in very good health, with a strong mind and a great
outlook (former pastor). Should the Urologist be treating this rise in PSA
with meds? Opinions please. I really don't have any more information to
pass along.

Signature
JerryK in Coastal South Carolina
I.P. Freely - 23 Feb 2009 13:34 GMT
> Should the Urologist be treating this rise in PSA with meds?
I can't think of a good reason to make his life worse. PSA is just a
number; ADT is REAL. Ask him which is more valuable to him ... a few
more happy years now or a few extra crappy months a few years from now
IF he's that lucky.
He can always go on ADT if mets ruin his QOL, but at that age ADT will
hit harder than with a younger man and its SEs will be much more likely
to be irreversible should he decide they're not worth it.
Even for a much younger man, the timing of ADT -- right after initial
treatment, when PSA rises, or when mets appear -- is highly debatable.
The older we get, the farther that scale tips towards "if it ain't broke
..."
I.P.
Steve Jordan - 23 Feb 2009 16:48 GMT
On February 23, 3Putt wrote:
> Should the Urologist be treating this rise in PSA with meds? Opinions please. I really
> don't have any more information to pass along.
Two points:
First, pay no attention to Mr. I P Chicken-Little, who knows zero about
how ADT would affect any particular individual and whose personal
experience is limited at best. He beats his anti-ADT drum at every
opportunity.
Second, I do not believe that a uro should be involved in the friend's
treatment. A uro is a surgeon, no more. It is possible, though, that
this particular uro might be one of the rare breed who actually knows
what he's doing outside the OR.
I recommend that the friend see a true cancer specialist, a medical
oncologist; preferably one who is familiar with treatment of PCa. A list
of PCa specialists in various fields will be found via this web portal
of the encyclopedic site of the Prostate Cancer Research Institute:
http://prostate-cancer.org/resource/find-a-physician.html
For the link to the list, scroll down about half way.
If a particular expert is inconveniently located (though I know of men
who travel thousands of miles to get the best treatment), I understand
that they are willing to work with a local med onc.
Regards,
Steve J
"I believe it is a mistake for many urologists to be involved in the
endocrine therapy of prostate cancer. Let me state why. Urologists are
surgeons and many times surgeons rush to a treatment without really
understanding what they are doing."
-- Stephen B. Strum, MD
Medical Oncologist
PCa Specialist
Steve Kramer - 23 Feb 2009 16:55 GMT
>A good friend had external radiation without chemo 3 years ago. 35-40
>treatments following an increasing PSA. At that time he was 80 years old.
[quoted text clipped - 5 lines]
>in PSA with meds? Opinions please. I really don't have any more
>information to pass along.
Yes.
Er, I mean no.
Oh, Hell. I don't know.
Your friend is in a precarious position, but you do not know nearly enough
of his history and condition to formulate an opinion.
Depending on how fast his PSA is rising, he is very definitely in danger of
dying from PCa. But, assuming he's been through initial treatment and/or
ADT and chemo and nothing is currently abating his cancer, then there are
few alternatives left in his war chest. If he can somehow reduce his PSA
(i.e., cancer), I would certainly do so, given QOL constraints, etc.
I would make one observation that he might be better treated by an
oncologist and would be surprised if he was not already.

Signature
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA <.1 <.1 <.1 .27 .37 .75 PSAD 0.19 years
EBRT 05-07/2002 @ 47
PSA .34 .22 .15 .21 .32 PSAD .056 years
Lupron 07/03 (1 mo) 8/03 and every 4 months there after
PSA .07 .05 .06 .09 .08 .132 .145 PSAD 1.4 years
Casodex added daily 07/06
PSA undetectable since, < 0.04 on 10/09/08
Illegitimati non carborundum
3Putt in Coastal SC - 23 Feb 2009 22:19 GMT
".> "3Putt in Coastal SC" <bogey@theswamp.com> wrote in message
> news:eaxol.227669$se4.23428@en-nntp-03.dc1.easynews.com...
>
[quoted text clipped - 11 lines]
>with the radiation Oncologist, and the cancer center in our community. I
>have passed these comments on to my friend.

Signature
JerryK in Coastal South Carolina
wrenden - 24 Feb 2009 14:53 GMT
>>A good friend had external radiation without chemo 3 years ago. 35-40
>>treatments following an increasing PSA. At that time he was 80 years old.
[quoted text clipped - 23 lines]
>I would make one observation that he might be better treated by an
>oncologist and would be surprised if he was not already.
Please define "QOL"
Thanks
wrenden
I.P. Freely - 24 Feb 2009 15:53 GMT
> Please define "QOL"
Quality of life.
I.P.
Steve Kramer - 24 Feb 2009 16:21 GMT
>>>A good friend had external radiation without chemo 3 years ago. 35-40
>>>treatments following an increasing PSA. At that time he was 80 years
[quoted text clipped - 33 lines]
>
> wrenden
Sorry. And welcome to ASCP.
QOL = Quality of Life and is generally supposed to be a very important
criterion when making decisions in the latter stages of cancer (or sometimes
earlier if side effects of meds are terrible).

Signature
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA <.1 <.1 <.1 .27 .37 .75 PSAD 0.19 years
EBRT 05-07/2002 @ 47
PSA .34 .22 .15 .21 .32 PSAD .056 years
Lupron 07/03 (1 mo) 8/03 and every 4 months there after
PSA .07 .05 .06 .09 .08 .132 .145 PSAD 1.4 years
Casodex added daily 07/06
PSA undetectable since, < 0.04 on 10/09/08
Illegitimati non carborundum