Hi, I would really appreciate any feedback on my husband's psa test
results which are very concerning.

01/08/31      3.0
02/07/26      2.4
03/12/24     14.3  (age 52)

(same lab was used each time)

All other blood and urine work done at the same time as the latest psa
test is normal.

He has not had a free psa test yet, but will be seeing a urologist
this week, who will no doubt schedule more testing and biopsy.

At the time of his first psa he was diagnosed with BPH by his regular
doctor and has been on daily flomax since then for urinary problems.
DRE's  have revealed nothing, apart from an enlarged prostate and the
doctor insisted all was fine, and didn't even see a need for regular
testing.  Am I correct in thinking that the flomax should have no
effect on his test results? Could the flomax have masked symptoms that
might otherwise have prompted us to seek further treatment?

Is it really possible to have such an increase over 17 months and it
not be caused by cancer? From everything I have read about psa
velocity, it seems unlikely.  Also, both his father and brother have
had prostate cancer, so we
realize the higher risk from that.

I've read so much about false negatives and repeat biopsies, and
wonder is
it more difficult to detect cancer in an enlarged prostate?

Sorry for all the questions!  It feels like the uro visit and
subsequent test results will take forever, and it makes me feel better
to put down my thoughts.  Although he is well aware of the
possibilities that may lie ahead, my husband is not a worrier by
nature and takes it all in his stride. I am the one who stays up at
night researching and doing the worrying for both of us (although I do
a pretty good job of keeping cool on the outside!)

Thanks for being there,
Ann