Welcome, Joseph K. You gave me a little start. My brother's name is Joseph
and he's kinda secretive about his ailments. Since he is only 11 months my
junior, I expect any day to hear that he has been Dx'd. But, onto your
problem....
At first when I saw this, it didn't make any sense to me. So, I graphed it
in Excel. It still doesn't. It is the strangest trend I think I've seen --
good or bad.
First, you experienced a significant drop after RT. That is common, but
some oncologists prefer a slower, more drawn out drop. But then it goes up,
levels out, then goes up again, levels out again. If you hadn't had Brachy,
I would have said it sounds more like BHP than PCa.
I can tell you that after Brachy, you want PSA to be less than 2.0. Better
if it's less than 1.0. Less the 4.0 doesn't count in the post-treatment
arena. That's for pre-treatment prostates and even then is becoming
somewhat of a myth.
What does your doctor say? Assuming he's giving you these numbers and not
telling you anything, my advice would be to seek out another urologist or
oncologist that is experienced in Prostate Cancer.

Signature
Prostate Cancer Survivor (so far), not a doctor
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000
PSA .1 .1 .1 .3 .4 .8
EBRT 05-07/2002 @ 47
PSA .3 .2 .2 .2 .3
Erection 05/12/2003 @ 48
HTbegins 07/21/2003 @ 48
PSA .1
Lupron 7/03, 8/03, 12/03
>
> PSA
[quoted text clipped - 17 lines]
> Had 88 seeds. I read different theories on PSA bounce. Should I hope for
> the PSA numbers to slowly decline, or be happy to stay under the 4 level?
Hello Joseph -- FYI and for comparison, here are my PSA numbers following
brachytherapy. I was seeded in October, 1999. I would be happy to send
you the Excel graphical version of my numbers via regular email.
Also, table 4 at
http://www.oncura.com/PDF/ijr0131_Grimm_10_year_survival.pdf shows how psa
seems to decline after brachytherapy in a lot of cases. I am no expert, but
it does seem that yours did not decline in the typical way.
Cheers,

Signature
John Hanley
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-------------------------------------------------
JPH PSA Results
4/97 5.2
2/98 9.5
3/98 5.4
6/98 5.5
6/99 7.4
11/99 6.7 <========== seeded 10/99
1/00 3.3
4/00 1.8
7/00 1.2
9/00 1.1
10/00 1.1
5/01 0.4
1/02 0.2
8/02 0.4
2/03 0.8
5/03 0.7
8/03 0.5
11/03 0.3
---------------------------------------
> PSA
>
[quoted text clipped - 16 lines]
> Had 88 seeds. I read different theories on PSA bounce. Should I hope for
> the PSA numbers to slowly decline, or be happy to stay under the 4 level?