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Medical Forum / Diseases and Disorders / Prostate Cancer / April 2008PSA Readings
Greetings from the Art Deco capital of the world - Napier, New Zealand I have been diagnosed with Prostate Cancer. I have had a biopsy which confirms the cancer. I have had a bone scan that confirms that the cancer is limited to the prostate. I am to be scheduled for surgery in June/July. Since I last saw my surgeon I have had another PSA Test. These are the results of all my PSA tests: FEB 04 4.9 OCT 06 6.4 MAY 07 8.7 NOV 07 8.0 FEB 08 7.7 APR 08 6.7 I would appreciate anyone making an observation as to the possible reason for the decline in my readings over the last year, and the significance thereof, if there is any. TIA > I have been diagnosed with Prostate Cancer. > I have had a biopsy which confirms the cancer. What was the Gleason score? This is vital. How many specimens were taken and how many of those specimens showed evidence of prostate cancer (PCa)? What is the clinical stage (CS)? This is expressed as the TNM (Tumor, Nodes, Metastases) score? Usually, at this early point, the CS is usually expressed as just the volume. For example, T2c, which means Tumor stage 2, involving both sides of the gland. > I have had a bone scan that confirms that the cancer is limited to the prostate. One hopes that that is accurate. The bone scan is notoriously crude. It will not detect micrometastases. > I am to be scheduled for surgery in June/July. > Since I last saw my surgeon I have had another PSA Test. [quoted text clipped - 5 lines] > FEB 08 7.7 > APR 08 6.7 What is the size of the prostate gland? The normal prostate produces PSA. The formula for computation of normal (benign) PSA is GV (gland volume) x 0.066 = benign PSA. Anything in excess requires explanation. Did the uro prescribe a course of treatment (tx) for possible infection? Cipro, for example. > I would appreciate anyone making an observation as to the possible reason > for the decline in my readings over the last year, and the significance > thereof, if there is any. The above record looks to me like an increase, not a decline. Without the Gleason information, it is simply impossible to understand the situation. I recommend that The Colonel join us at http://www.pcainaz.org/ which was for Arizona folks until the rest of the world discovered us. There is a fine contributor named "Chris" who is also an Enzed. Please join us on our international chat, accessible via the above site on what I think is Sunday AM in NZ. It's necessary to register, which is easy and will not result in spam. Regards, Steve J (Esteban) > TIA >> I have been diagnosed with Prostate Cancer. >> I have had a biopsy which confirms the cancer. [quoted text clipped - 12 lines] > One hopes that that is accurate. The bone scan is notoriously crude. It > will not detect micrometastases. The test of choice for this would be the CT scan. >> I am to be scheduled for surgery in June/July. >> Since I last saw my surgeon I have had another PSA Test. [quoted text clipped - 34 lines] > >> TIA Larry wrote, responding to me: (ka-snip) >> The above record looks to me like an increase, not a decline. Oops. Must have had my eyes crossed. Regards, Steve J On Apr 25, 5:33 pm, "Colonel Saunders" <ColonelSand...@ihug.co.nz> wrote: > Greetings from the Art Deco capital of the world - Napier, New Zealand > [quoted text clipped - 15 lines] > thereof, if there is any. > TIA Hi Colonel...It could be normal variation, a lab error, or something else. Perhaps the following questions might help point to something: 1) are all measurements from the same lab? 2) any new meds or supplements? 3) do you have a history of prostatitis, or any other UTI's? 4) is your testosterone low or falling? ...ron > Greetings from the Art Deco capital of the world - Napier, New Zealand > [quoted text clipped - 14 lines] > for the decline in my readings over the last year, and the significance > thereof, if there is any. PSA values can jump around for a variety of reasons. But at this point, it is moot, if you have been diagnosed with prostate cancer through a biopsy. > TIA > Greetings from the Art Deco capital of the world - Napier, New Zealand > [quoted text clipped - 14 lines] > for the decline in my readings over the last year, and the significance > thereof, if there is any. Your biopsy should have given you more numbers, including Stage and Gleason, and what is your age? Based on your 2004, 2006, and 2007 PSAs, I'm wondering if your doctor was alarmed and has been treating your for another prostate problem. If so, especially if you were given new meds in May 2007, or maybe even statins or Celebrex for other problems, your PSA might have gone down. It matters not in the long run. You cancer is confirmed and will not leave your body on its own. Sorry to welcome you to our club.  SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA <.1 <.1 <.1 .27 .37 .75 PSAD 0.19 years EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 PSAD .056 years Lupron 07/03 (1 mo) 8/03 and every 4 months there after PSA .07 .05 .06 .09 .08 .132 .145 PSAD 1.4 years Casodex added daily 07/06 PSA <0.04, <0.05, <0.04, <0.04, <0.1 2/12/08 Non Illegitimi Carborundum Steve answered Colonel Saunders with: > ...especially if you were given new meds in May 2007, or maybe > even statins or Celebrex for other problems, your PSA might have > gone down. Steve, Is there somewhere I can look into the relationship between statins/celebrex (I've had both) and declining PSA? Joe N. ___ Blue Wave/QWK v2.12 |
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