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Medical Forum / Diseases and Disorders / Prostate Cancer / January 2008

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The meaning of PAP, CgA and CEA numbers

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WhiteSoxFan - 04 Jan 2008 23:03 GMT
Are the results of PAP (Prostatic Acid Phosphatase) , CgA
(Chromogranin A) and CEA (Carcinoembryonic antigen) tests meaningful
by themselves or are multiple tests needed to track  velocity or
changes in values necessary for meaningful diagnostic purposes? I
just recently asked my oncologist for these tests because of my
elevated Gleason (4+4=8) at time of RP. Its been two years since my RP
with consistent <0.10 PSAs but after reading some stuff regarding high
Gleasons and lower than usual PSA readings, I sort of wanted to be a
little more aggressive with the diagnostics. It would have been nice
to have had them done at the time but I was not knowledgeable enough
then to request them. Just for the record, my PAP was 0.7, my CgA was
8.8 and my CEA was 1.1 and I have no idea what those numbers mean.

Thanks,

WhiteSoxFan
Steve Jordan - 04 Jan 2008 23:51 GMT
On January 4, WSF wrote:

> Are the results of PAP (Prostatic Acid Phosphatase) , CgA
> (Chromogranin A) and CEA (Carcinoembryonic antigen) tests meaningful
> by themselves or are multiple tests needed to track  velocity or
> changes in values necessary for meaningful diagnostic purposes?

It is my understanding that tests of these markers will give one a
snapshot of where he stands. I do not know of any reason similar to PSA
tracking to track the results over time, but OTOH what harm is there in
doing so?

(su-nip)

> Just for the record, my PAP was 0.7, my CgA was
> 8.8 and my CEA was 1.1 and I have no idea what those numbers mean.

And likely the medic doesn't either, more's the pity.

PAP = prostatic acid phosphatase, normal range 0-3.5.
CGA = chromogranin-alpha, normal range < 14.3.
CEA = carcino-embryonic antigen, normal range < 4.0

It appears unlikely to this amateur that WSF has much to worry about re:
neuroendocrine PCa.

Relax. Have a drink. Find a medic who understands PCa.

Regards,

Steve J
 
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