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Medical Forum / Diseases and Disorders / Prostate Cancer / January 2008Question re: PSA numbers
I was diagnosed with Pca in August,2007. My numbers are: Age-60 PSA 3.17 (Had doubled in 18 months) Stage T1c Gleason 6 (3+3) Bone Scan & CAT Scan-Negative Active Surveillance I will be getting another PSA next week. Can the PSA go down? If so, why? Thanks, Sy > I was diagnosed with Pca in August,2007. > [quoted text clipped - 13 lines] > > Sy Sy...With PCa anything is possible. Perhaps you had an infection (infection "is" cell death, when the cell wall dissolves, the cell contents - including PSA - leak more easily into the bloodstream) last time which has since cleared up. Maybe you had done something that "massaged" the prostate (which could cause it to leak additional PSA into the bloodstream) prior to your last test. A lab error is also a possibility. Good luck with the next PSA!..Best wishes and good health, ron >> I was diagnosed with Pca in August,2007. >> [quoted text clipped - 22 lines] > possibility. Good luck with the next PSA!..Best wishes and good > health, ron To underscore: I had a PSA reading of 11.7 at one hospital's lab over a year ago, and a reading of 9.7 less than two weeks later. The number by itself is not that significant. > I was diagnosed with Pca in August,2007. > [quoted text clipped - 9 lines] > I will be getting another PSA next week. Can the PSA go down? If so, > why? PSA can vary for quite a few reasons, some of which ron described. So it could go down. For exasmple, in my case, my PSA went from 3.3 to 4.5 over a period of about a year, and then on retesting it dropped to 3.8. But I had already had a biopsy and been diagnosed with prostate cancer, so thee exact value of the PSA was moot. Your situation seems similar to mine in that you already know that you have prostate cancer. If your PSA drops a bit on your next test, that won't change the situation much. It is true that the PSA value is one factor in deciding what to do next, but it is highly unlikely to drop enough to change the situation. The Gleason score and other information obtained from the biopsy already provides enough information. > Thanks, > > Sy Your situation is very similar to mine back in 2005, I was 65 by then. Early detection gives you all the advantage you need to win that battle Don't wait for too long Best of luck and speedy recovery RR >> I was diagnosed with Pca in August,2007. >> [quoted text clipped - 26 lines] >> >> Sy > I was diagnosed with Pca in August,2007. > [quoted text clipped - 9 lines] > I will be getting another PSA next week. Can the PSA go down? If so, > why? If you have a PSAD of 18 months, you can expect a PSA next week of somewhere around 4.00. You can guess at a PSAD with only two measurements. You cannot really know what your PSAD is until you have had three or more. Therefore, you can have a PSA next week of 5.00 and determine that your PSAD is really only a year. Or, you might have a slight rise and find that your PSAD is really two years. To further complicated things, your PSAD can change. However, to answer your question more directly, yes, it can go down. I don't know why it does. You would think that with a group of untreated cancer cells that are reproducing and causing havoc, each all the while producing a fairly constant amount of PSA, that the PSA could never decrease. But, in fact, sometimes it does. And, I suspect if anyone knew why, they'd be much closer to a cure than they are. Could be the "blood sample" or the sensitivity of the test, or the lab that does the test also. A Dr. told me that PSA test results can vary depending on the lab.......... Anyway, getting a PSA test, and with your prior lab work done, may give you more information that will help you make a decision toward dealing with prostate cancer. This was a difficutl time for me as well, and I had many thoughts, and treatment options to dwell about. I do wish you the best direction. jloomis >> I was diagnosed with Pca in August,2007. >> [quoted text clipped - 26 lines] > decrease. But, in fact, sometimes it does. And, I suspect if anyone knew > why, they'd be much closer to a cure than they are. |
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